Wed.Nov 20, 2024

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U.S. Postpartum Depression Diagnoses Doubled in a Decade

Drugs.com

WEDNESDAY, Nov. 20, 2024 -- Rates of postpartum depression have more than doubled in little over a decade among American women, a new analysis shows. While about 1 in every 10 new moms (9.4%) suffered postpartum depression in 2010, that number rose.

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Flagship, Pfizer alliance yields two more startup deals

BioPharma Drive: Drug Pricing

Pfizer will work with Ampersand Biomedicines and Montai Therapeutics to find drugs for obesity and lung cancer, respectively, adding to collaborations it previously formed with other Flagship startups.

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Turning carbon emissions into methane fuel

Science Daily: Pharmacology News

Chemists have developed a novel way to capture and convert carbon dioxide into methane, suggesting that future gas emissions could be converted into an alternative fuel using electricity from renewable sources.

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Caring for Yourself While Caring for Others: Practical Tips for Caregivers

Antidote

Being a caregiver is one of the most selfless and demanding roles you can take on. Whether you're looking after a parent, spouse, child, or loved one, juggling all of the daily responsibilities that come with it can quickly feel overwhelming. With so much focus on taking care of others, it’s easy to put yourself and your needs on the back burner. While your focus is understandably on your loved one, it’s important to remember that your own well-being matters too.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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About 1 in 10 U.S. Adults Have High Cholesterol

Drugs.com

WEDNESDAY, Nov. 20, 2024 -- Nearly 1 in every 10 American adults is living with high levels of cholesterol in their arteries, according to the latest report from the U.S. Centers for Disease Control and Prevention.The data, from 2021 through 2023.

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Oldest known alphabet unearthed in ancient Syrian city

Science Daily: Pharmacology News

Researchers have discovered evidence of the oldest alphabetic writing in human history. The writing was etched onto clay cylinders discovered during a dig at an ancient Syrian city.

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Listening for early signs of Alzheimer's disease

Science Daily: Pharmacology News

People with Alzheimer's exhibit a loss of motor control along with cognitive decline, and one of the earliest signs of this decay can be spotted in involuntary eye movements known as saccades. These quick twitches of the eyes in Alzheimer's patients are often slower, less accurate, or delayed compared to those in healthy individuals. Researchers are exploring an alternative method using a more ubiquitous and less intrusive technology: earpiece microphones.

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Earlier Type 2 Diabetes Diagnoses Bring Higher Odds for Dementia

Drugs.com

WEDNESDAY, Nov. 20, 2024 -- A type 2 diabetes diagnosis before age 50 comes with a health risk that patients might not expect.Especially if they are obese, these folks are more likely to develop dementia later, new research warns."Our study.

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A bioinspired capsule can pump drugs directly into the walls of the GI tract

Science Daily: Pharmacology News

Inspired by the jets of water that squids use to propel themselves through the ocean, a team developed an ingestible capsule that releases a burst of drugs directly into the lining of the stomach or other organs of the digestive tract.

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Child-Teacher Bond in Early Education Could Have Lasting Impact

Drugs.com

WEDNESDAY, Nov. 20, 2024 -- Fostering good relationships with teachers in the early grades may have long-lasting benefits, new research suggests."These early connections significantly influence not only academic achievement, but also social and.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Synchronized movement between robots and humans builds trust, study finds

Science Daily: Pharmacology News

Trust between humans and robots is improved when the movement between both is harmonized, researchers have discovered.

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California Child Tests Positive for Bird Flu

Drugs.com

WEDNESDAY, Nov. 20, 2024 -- A child in California has tested positive for bird flu, despite having no known contact with infected animals, state officials reported Tuesday."California has identified a possible bird flu case in a child in Alameda.

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Mapping 1.6 million gut cells to find new ways treat disease

Science Daily: Pharmacology News

By combining 25 datasets, researchers have created the largest cohesive cell atlas of the human gut and uncovered a new way that stomach cells may play a role in Inflammatory Bowel Disease.

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Four Million Americans Could Lose Health Coverage Once ACA Credits Expire

Drugs.com

WEDNESDAY, Nov. 20, 2024 -- If Congress lets healthcare tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Researchers develop clinically validated, wearable ultrasound patch for continuous blood pressure monitoring

Science Daily: Pharmacology News

A re-engineered wearable ultrasound patch for continuous and noninvasive blood pressure monitoring has undergone comprehensive clinical validation on over 100 patients, marking a major milestone in wearable technology research. The soft, stretchy patch provides precise, real-time readings of blood pressure deep within the body. It could offer a simpler and more reliable alternative to current clinical methods.

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A-fib Plus Heart Failure a Dangerous Combo

Drugs.com

WEDNESDAY, Nov. 20, 2024 -- For the 4 in 10 patients with newly diagnosed heart failure who also have the heart rhythm disorder atrial fibrillation, the prognosis can be poor."Atrial fibrillation can make heart failure much more problematic, and.

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Healthy women have cells that resemble breast cancer

Science Daily: Pharmacology News

A new study finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods. The study discovered that at least 3% of normal cells from breast tissue in 49 healthy women contain a gain or loss of chromosomes, a condition known as aneuploidy, and that they expand

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Surgeon General Says U.S. Smoking Rates Have Tumbled, But Not for Everyone

Drugs.com

WEDNESDAY, Nov. 20, 2024 -- Although the United States has made significant headway in curbing cigarette smoking and secondhand smoke exposure, a new report finds deep divisions remain and they run along predictable fault lines.Disparities in.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Athletes have significantly better working memory than sedentary people

Science Daily: Pharmacology News

A recently published meta-analysis reveals an advantage in sports-related information processing compared to non-athletes. The data consisted of 21 studies involving a total of 1455 participants. Athletes had better working memory than non-athletes and this advantage was further enhanced when athletes were compared to sedentary people.

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Chasing new ‘checkpoints,’ startup Valora emerges from a Nobel winner’s lab

BioPharma Drive: Drug Pricing

Built around research by Stanford scientist Carolyn Bertozzi and MIT researcher Jessica Stark, Valora Therapeutics is designing drugs to target glyco-immune checkpoints.

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Thanksgiving special: Dinosaur drumsticks and the story of the turkey trot

Science Daily: Pharmacology News

Wings may be the obvious choice when studying the connection between dinosaurs and birds, but a pair of paleontologists prefer drumsticks. That part of the leg, they say, is where fibular reduction among some dinosaurs tens of millions of years ago helped make it possible for peacocks to strut, penguins to waddle, and turkeys to trot.

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Sage’s string of research failures continues

BioPharma Drive: Drug Pricing

Negative results from a Huntington’s trial add to a calamitous year for Sage, which last month decided to overhaul its research, reconfigure its executive team and lay off a third of its staff.

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An innovative antibiotic for drug-resistant bacteria

Science Daily: Pharmacology News

Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs -- so they don't work well, or even at all -- means new ones are urgently needed. Researchers have demonstrated a potential antibacterial treatment from a modified darobactin, a compound originally from a bacterium. The team reports proof-of-concept animal trials on infections caused by bacteria, including E. coli, that are known to develop drug resistance.

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New Draft Guidance Provides Detailed (and Burdensome) Recommendations for Chemical Assessments to Support Medical Device Biocompatibility

FDA Law Blog: Biosimilars

By Adrienne R. Lenz, Principal Medical Device Regulation Expert & Kristy Katzenmeyer-Pleuss, Regulatory and Biological Safety Consultant* — FDA recently issued a draft guidance, Chemical Analysis for Biocompatibility Assessment of Medical Devices , which describes chemical characterization methods that may be used to demonstrate biocompatibility of a medical device as an alternative to conducting certain biological testing.

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Superior photosynthesis abilities of some plants could hold key to climate-resilient crops

Science Daily: Pharmacology News

Scientists discovered a stretch of DNA in both C3 plants, like wheat and soybeans, and C4 plants, like corn and sorghum, that is responsible for optimizing C4 plant photosynthesis and making them better at withstanding heat and drought. The findings are insightful in understanding how some plants evolved to be more efficient, and may now be used as a springboard for turning C4 photosynthesis on in C3 plants -- an important step for creating sustainable crop populations in the face of climate cha

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Adaptive by Design: The Promise of Generative Interfaces

Perficient: Drug Development

Imagine a world where digital interfaces anticipate your needs, understand your preferences, and adapt in real-time to enhance your experience. This is not a futuristic daydream, but the promise of generative interfaces. Generative interfaces represent a new paradigm in user experience design, moving beyond static layouts to create highly personalized and adaptive interactions.

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Human immune system is 'ready to go' long before birth

Science Daily: Pharmacology News

The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, autoimmunity, and cancer.

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Quantum Computing and Cybersecurity: Preparing for a Quantum-Safe Future

Perficient: Drug Development

Quantum computing is rapidly transitioning from theory to reality, using the principles of quantum mechanics to achieve computational power far beyond traditional computers. Imagine upgrading from a bicycle to a spaceship—quantum computers can solve complex problems at extraordinary speeds. However, this leap in computing power poses significant challenges, particularly for cybersecurity, which forms the backbone of data protection in our digital world.

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Sweet tooth- Ethiopian wolves seen feeding on nectar

Science Daily: Pharmacology News

For the first time, Ethiopian wolves have been documented feeding on the nectar of Ethiopian red hot poker flowers. This is the first large carnivore species ever to be documented feeding on nectar. In doing so, the wolves may act as pollinators -- perhaps the first known plant-pollinator interaction involving a large carnivore.

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How Technology Advances Can Streamline Development and Manufacturing

Fierce BioTech

How Technology Advances Can Streamline Development and Manufacturing Explore how advancements in technology are revolutionizing the development and manufacturing of antibody-drug conjugates (ADCs), enabling faster, more efficient oncology breakthroughs with enhanced safety and efficacy. Download now. smarcus Wed, 11/20/2024 - 11:05 Explore how advancements in technology are revolutionizing the development and manufacturing of antibody-drug conjugates (ADCs), enabling faster, more efficient oncol

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Researchers catalog the microbiome of US rivers

Science Daily: Pharmacology News

Scientists have detailed both broad and specific information about the presence and function of microorganisms in rivers covering 90% of the watersheds in the continental U.S. Cataloging the microbiome of these rivers is the result of a years-long participatory science effort.

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Navigating the Complex Landscape: Key Challenges in Biosimilar Development

Drug Patent Watch

The pharmaceutical industry is constantly evolving, and one of the most exciting areas of growth is the development of biosimilars. These biological products, designed to be highly similar to existing approved biologics, offer the promise of more affordable treatment options for patients. However, the journey from concept to market is fraught with challenges.

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Early skeleton map reveals how bones form in humans

Science Daily: Pharmacology News

Full view of how bones and joints form in the first trimester uncovers cells and pathways that could help diagnose and treat skeletal conditions in the future.

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