Broad Institute

JANUARY 19, 2024

Study reveals how some bacterial infections become chronic By Leah Eisenstadt January 19, 2024 Breadcrumb Home Study reveals how some bacterial infections become chronic Scientists uncover mutations that allow Salmonella to fly under the immune system’s radar for years By Leah Eisenstadt January 19, 2024 Credit: James Archer, Medical Illustrator, Courtesy of CDC/ Antibiotic Resistance Coordination and Strategy Unit A 3D, computer-generated image of non-typhoidal Salmonella bacteria.

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Immune Response Treatment Disease Research 119

BioPharma Drive: Drug Pricing

JANUARY 19, 2024

Phase 3 trial results showed Lutathera cut the risk of disease progression or death by 72% as initial treatment for gastroenteropancreatic neuroendocrine tumors, or GEP-NETs.

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Trials Treatment Disease Drugs 118

Perficient: Drug Development

JANUARY 19, 2024

Many retailers are embarking on a digital transformation to modernize and scale their order management system (OMS) solution. Built on a modern architecture, the solution wraps Docker containers around order management business services. This architecture streamlines application management and the release of new functionality. The container technology also supports varying levels of technical acumen, business continuity, security, and compliance.

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Compliance Marketing Licensing Licensing 118

Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 19, 2024 -- People coming off antidepressants often struggle with emotional and social turmoil, especially if they quit their meds cold turkey, a new study reports.Challenges reported by patients quitting antidepressants included.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Perficient: Drug Development

JANUARY 19, 2024

In the world of Generative Artificial Intelligence (AI), a new era of large language models has emerged with the remarkable capabilities. ChatGPT , Gemini , Bard and Copilot have made an impact in the way we interact with mobile device and web technologies. We will perform a comparative analysis to highlight the capabilities of each tool. ChatGPT Gemini Bard Copilot Training Data Web Web Web Web Accuracy 85% 85% 70% 80% Recall 85% 95% 75% 82% Precision 89% 90% 75% 90% F1 Score 91% 92% 75% 84% Mu

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Packaging Marketing 115

Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 19, 2024 -- Your office chair could be a killer.New research shows that folks who spent most of their workday sitting were 16% more prone to an early death, compared to folks in non-sitting jobs. The Taiwanese study did offer workers a.

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Research 111

Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 19, 2024 -- Folks who drop pounds to help control their diabetes receive other substantial heath benefits for all their efforts, a new study says.Substantial weight loss that led to even a short-lived remission in type 2 diabetes also.

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Disease 105

Drug Target Review

JANUARY 19, 2024

Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My journey in the field of science has been highly enriching and gratifying. However, when I started my career in the pharma field, it was a male-dominated industry with minimal opportunities for women to grow and advance as leaders. I started working as a trainee immediately after submitting my PhD thesis in Analytical chemistry to Pune university in India but initially felt immense pressur

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Synthetic Chemistry Analytical Chemistry Pharmaceuticals Pharma Companies 105

Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 18, 2024 -- Getting bored with your treadmill or exercise bike?Picking up a couple dumbbells instead of lacing up your running shoes once in a while won’t do your heart any harm, a new study reports.Splitting the recommended amount.

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Fierce BioTech

JANUARY 19, 2024

While much attention has been given to the novel science behind cell and gene therapies (CGTs), the success of every precision medicine starts and ends with the patient. | Cell and gene therapy patients often require support throughout their treatment journey. Learn key considerations for developing patient support programs.

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Therapies Science Treatment 91

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 19, 2024 -- Cases of salmonella linked to recalled charcuterie meats have doubled in just over two weeks, triggering an expansion of the recall, the U.S. Centers for Disease Control and Prevention announced Thursday. "Since the last.

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Disease 105

Science Daily: Pharmacology News

JANUARY 19, 2024

Researchers have found a new way to supply the body with insulin. The medication that can be taken orally has already been tested on baboons, in which it was found to lower the blood sugar levels without causing hypoglycemia. The new insulin is ready to be tested on humans in 2025. If all goes well, diabetics are facing an easier life without injections.

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Research 95

SCIENMAG: Medicine & Health

JANUARY 19, 2024

One in three children who suffer from bacterial meningitis live with permanent neurological disabilities due to the infection. This is according to a new epidemiological study led by Karolinska Institutet and published in leading medical journal JAMA Network Open.

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International 81

Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 19, 2024 -- Folks with life-threatening chronic illnesses can receive effective support over the telephone as they manage their condition day by day, a new clinical trial finds.Seriously ill veterans living with lung or heart disease.

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Clinical Trials Trials Disease 81

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

SCIENMAG: Medicine & Health

JANUARY 19, 2024

The most important support person for women to succeed in their ambition to breastfeed is the new mother’s partner. The partner also needs to be included through more support from healthcare professionals.

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Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 19, 2024 -- The effects of climate change could be shaving half a year off your life, a new study warns.Increases in temperature and rainfall -- and the public health problems that come with them -- are projected to decrease average.

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SCIENMAG: Medicine & Health

JANUARY 19, 2024

There are approximately 425 million people worldwide with diabetes. Approximately 75 million of these inject themselves with insulin daily. Now they may soon have a new alternative to syringes or insulin pumps. Scientists have found a new way to supply the body with smart insulin.

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Crown Bioscience

JANUARY 19, 2024

Q: How are organoids prepared for High-Throughput Screening (HTS)? A: Organoids are cultured and maintained in a hydrogel/Matrigel as multi-cellular structures that need to be mechanically sheared to split them into fragments and seeded at approximately 300 organoid fragments (5-20 cells per structure) per well. But this can vary based on the organoid type and how quickly the organoids grow within the timeframe of the assay.

Drugs 71

Drugs 71

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

BioPharma Drive: Drug Pricing

JANUARY 19, 2024

The Senate HELP committee, which is seeking testimony from J&J's Joaquin Duato and Merck's Robert Davis, hasn't issued a subpoena since 1981.

Testimonials 64

Testimonials Drugs 64

Drug Patent Watch

JANUARY 19, 2024

Orphan drug exclusivity is granted to drugs addressing rare ‘orphan diseases’ — those affecting fewer than 200,000 Americans. The protection granted to orphan drugs is quite strong. The FDA is… The post Pharmaceutical companies with the most orphan drugs appeared first on DrugPatentWatch - Make Better Decisions.

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Pharmaceutical Companies Pharmaceuticals Drugs FDA 59

Agency IQ

JANUARY 19, 2024

The EMA and FDA are implementing revisions to an important quality guideline, addressing viral safety for products derived from human or animal cell lines (ICH Q5A R(2)). The revisions provide important updates to the 1999 version, acknowledging a field that’s grown and changed significantly in the interval. The final version includes some extensive updates to a 2022 draft revision, to include reduced use of animals in testing and development of these products.

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FDA Production 59

Drug Patent Watch

JANUARY 19, 2024

Annual Drug Patent Expirations for RAVICTI Ravicti is a drug marketed by Horizon Therap Us and is included in one NDA. It is available from one supplier. There are sixteen… The post New patent for Horizon Therap drug RAVICTI appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Agency IQ

JANUARY 19, 2024

The EPA has published a finalized version of its policy assessment for oxides of nitrogen and sulfur, as well as particulate matter. The agency’s final policy assessment recommends maintaining current secondary standards for some substances like PM2.5 and offers policy options for consideration to amend others. Fill out the form to read the full article.

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Drug Patent Watch

JANUARY 19, 2024

Annual Drug Patent Expirations for TAZVERIK Tazverik is a drug marketed by Epizyme Inc and is included in one NDA. It is available from one supplier. There are twenty-four patents… The post New patent for Epizyme Inc drug TAZVERIK appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Agency IQ

JANUARY 19, 2024

The FDA today issued a funding opportunity announcement seeking to fund work that explores how real-world data sources could couple with artificial intelligence (AI)/machine learning (ML) algorithms to compare clinical outcomes between complex generic and brand-name products. The work could represent early steps toward modernizing one part of FDA’s regulation of this complicated product class.

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FDA Research Regulations Production 59

Drug Patent Watch

JANUARY 19, 2024

Annual Drug Patent Expirations for XYOSTED+%28AUTOINJECTOR%29 Xyosted (autoinjector) is a drug marketed by Antares Pharma Inc and is included in one NDA. It is available from one supplier. There are… The post New patent for Antares Pharma drug XYOSTED (AUTOINJECTOR) appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Agency IQ

JANUARY 19, 2024

This week, the EMA released its 2023 New Medicines Highlights report, providing insights into the number of opinions provided and the types of products reviewed. Here AgencyIQ analyzes this new report against those from previous years, identifying notable changes in the total number and types of reviews, with an apparent return to pre-pandemic volume.

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Production 59

Drug Patent Watch

JANUARY 19, 2024

Annual Drug Patent Expirations for HALAVEN Halaven is a drug marketed by Eisai Inc and is included in one NDA. It is available from two suppliers. There are two patents… The post New patent expiration for Eisai Inc drug HALAVEN appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Agency IQ

JANUARY 19, 2024

The Commission has long aspired to realize its one substance, one assessment concept in the EU’s chemical regulatory regime. With the publication of three proposed legal acts, this concept is one step closer to streamlining the way the bloc regulates chemicals. Fill out the form to read the full article.

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Packaging Regulations 59

Drug Patent Watch

JANUARY 19, 2024

Annual Drug Patent Expirations for VIMOVO Vimovo is a drug marketed by Horizon and is included in one NDA. It is available from two suppliers. There are three patents protecting… The post New patent for Horizon drug VIMOVO appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 19, 2024 -- People are more prone to coming down with a common gastrointestinal infection on hot, humid days, new research shows.The British study suggests that climate change and global warming could increase cases of diarrheal.

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Research 59

Drug Patent Watch

JANUARY 19, 2024

Annual Drug Patent Expirations for RYZUMVI Ryzumvi is a drug marketed by Ocuphire and is included in one NDA. The generic ingredient in RYZUMVI is phentolamine mesylate. Additional details are… The post New patent for Ocuphire drug RYZUMVI appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Drugs.com

JANUARY 19, 2024

FRIDAY, Jan. 19, 2024 -- Electric scooters might seem a fun way to zip about, but they’re also a pricey hazard to riders’ health, a new study argues.Orthopedic treatment for 82 patients injured in e-scooter wrecks averaged more than $28,400 per.

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