Fri.Jan 12, 2024

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A 'Universal' COVID Vaccine Could Save Billions If Another Pandemic Strikes

Drugs.com

FRIDAY, Jan. 12, 2024 -- A universal coronavirus vaccine could have saved millions of lives and billions of dollars if one had been available prior to the pandemic, a new study argues. Further, a universal vaccine -- one that targets parts of the.

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Living with PSC: What to know about primary sclerosing cholangitis

Antidote

An estimated 1 in 10,000 people have primary sclerosing cholangitis (PSC) , a condition that impacts the bile ducts that run between the liver, the gallbladder, and the small intestine. The liver produces bile to transport to the gallbladder for storage, or to the small intestine where it aids in the digestion of fats. In the case of PSC, there is inflammation in the bile ducts (cholangitis) which leads to scarring (sclerosis) that narrows the ducts.

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COVID Can Threaten Sickle Cell Patients, But Too Few Are Vaccinated

Drugs.com

FRIDAY, Jan. 12, 2024 -- Sickle cell disease is one of many chronic health conditions that dramatically increases the risk of hospitalization and death in people infected by COVID-19.Unfortunately, folks with sickle cell disease are much less.

Vaccine 141
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Backed by billionaires, a new biomedical institute tests an unorthodox approach

BioPharma Drive: Drug Pricing

Arena BioWorks, which will be led by Harvard University scientist Stuart Schreiber, seeks to blend academic and venture capital drug research models.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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How AI is accelerating the future of precision medicine

Drug Target Review

How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? Most drugs do not work in all people. This one size fits all approach to drug prescribing still pervades in mostly all therapy areas except oncology. So, knowing an individual and something about their profile, whether that be biomarkers such as genomic data, blood-based markers or even transcriptomics of tissues or blood, p

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Biotech Venture Ecosystem: Quick Health Check

LifeSciVC

Biotech feels like it’s got some wind in its sails here at the start of 2024, with positive sentiments from the JPM conference. Indeed, the public equity markets feeling somewhat buoyant for the first time in ages. With the close out of 2023, it’s time to take stock of the health of the private venture ecosystem. Analyzing Pitchbook data for venture funding into US-based biopharma companies, at least four themes are worth highlighting related to overall funding, startup creation, mega-rounds, an

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More Trending

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Kessler Foundation scientist awarded prestigious federal grant for novel, mixed-method study on Latinos with multiple sclerosis

SCIENMAG: Medicine & Health

East Hanover, NJ – January 12, 2024 – A research scientist at Kessler Foundation has been awarded a highly competitive Mentored Patient-Oriented Research Career Development Award (K23) from the National Institute on Minority Health and Health Disparities, a part of the National Institutes of Health (NIH).

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Soy, Nuts, Beans May Help Prevent Breast Cancer's Return

Drugs.com

FRIDAY, Jan. 12, 2024 -- Women who've survived breast cancer may want to up their dietary intake of soy, nuts, beans and whole grains, a new analysis finds.A higher intake of soy compounds called isoflavones was especially tied to better odds that.

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Building trust and saving lives: A community approach to genetic education

SCIENMAG: Medicine & Health

Changes to DNA, known as mutations, can increase the likelihood of developing cancer. Specifically, people with mutations in their BRCA 1 and 2 genes are substantially more likely to develop hereditary breast and ovarian cancers. But how do people know if they have these mutations? Credit: Medical University of South Carolina. Photograph by Sarah Pack.

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Race Still Plays Role in U.S. Cancer Death Rates

Drugs.com

FRIDAY, Jan. 12, 2024 -- While cancer death rates have fallen among Americans generally over the past two decades, a new study finds Black Americans are still more likely than whites to die from the disease. There has been some improvement in.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Novel approach for lymph node metastasis treatment

SCIENMAG: Medicine & Health

Researchers at Tohoku University have discovered a new approach for treating lymph node metastasis. Anticancer drugs are administered directly into the LNs under ultrasound guidance (Lymphatic Drug Delivery System or LDDS) to target sentinel lymph nodes (LNs) and generate antitumor effects locally, preventing distant metastasis.

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Science confirms it: Love leaves a mark on the brain

Science Daily: Pharmacology News

The brain produces more of the pleasure-inducing hormone dopamine when we're longing for or hanging out with our partner, new research suggests. But when we break up, their unique 'chemical imprint' fades away. The study centers around prairie voles, which have the distinction of being among the 3 percent to 5 percent of mammals that form monogamous pair bonds.

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Healthy Hearts for Women event marks 10 years of raising awareness

SCIENMAG: Medicine & Health

LEXINGTON, Ky. (Jan. 12, 2024) — The University of Kentucky will mark a decade of raising awareness and continuing its effort to warn women about the dangers of heart disease with the annual Healthy Hearts for Women Symposium. Credit: Peera_Sathawirawong, iStock/Getty Images Plus LEXINGTON, Ky. (Jan.

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Repairing the Patient Journey: How Pharma Can Fix the Obvious–and Not So Obvious–Breaking Points of Nonadherence

Drug Channels

Today’s guest post comes from Maria Kirsch, President, Patient Services, Krista Pinto, President, Deployment Solutions, and Mike Scott, Senior Vice President, Specialty Consulting at EVERSANA. Maria, Krista, and Mike discuss the key reasons why patients abandon drug therapy. They then describe EVERSANA’s approach for helping manufacturers and healthcare providers improve adherence and health outcomes.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Goldstein selected to help lead statewide task force addressing heart disease and stroke

SCIENMAG: Medicine & Health

LEXINGTON, Ky. (Jan. 12, 2024) — Larry Goldstein, M.D., chair of the University of Kentucky Department of Neurology, has been selected to serve as co-chair of The Kentucky Heart Disease and Stroke Prevention (KHDSP) Task Force representing stroke systems of care across the state. Credit: Photo by Shaun Ring. LEXINGTON, Ky. (Jan. 12, 2024) — Larry Goldstein, M.D.

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FDA Finds No Link to Suicide With Drugs Like Wegovy, Ozempic

Drugs.com

FRIDAY, Jan. 12, 2024 -- Drugs like Wegovy and Ozempic, which have become a wildly popular way to lose weight or battle diabetes, show no link to suicidal thoughts or actions, the U.S. Food and Drug Administration said Thursday.“Our preliminary.

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Uncovering the link to combating muscle atrophy caused by ageing and immobility

SCIENMAG: Medicine & Health

The loss of muscle mass, or muscle atrophy, is a relatively common condition in today’s aging and increasingly sedentary societies. While the disuse of muscles is the most frequent catalyst for muscle atrophy, there are several other possible causes, including chronic diseases, injury, and exposure to low-gravity environments, such as in spaceships.

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Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging

Science Daily: Pharmacology News

Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Carvedilol May Help Childhood Cancer Survivors Avoid Later Heart Failure

Drugs.com

FRIDAY, Jan. 12, 2024 -- Childhood cancer survivors are at increased risk of developing heart failure later in life, due to the chemotherapy that was used to save their lives. But an already approved drug might help reduce that risk, according to a.

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Study uncovers potential origins of life in ancient hot springs

Science Daily: Pharmacology News

A research team investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including fatty acids stretching up to 18 carbon atoms in length.

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Fish as Model Organisms in Scientific Research

biobide

Fish serve as fascinating models in scientific research, offering valuable insights across various fields such as genetics, toxicology, developmental biology, and environmental studies. Among the diverse species studied, zebrafish, fathead minnow, carp, Japanese medaka, guppies, and bluegills stand out for their unique characteristics and contributions to scientific exploration.

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Recursion’s Chris Gibson on AI in biotech, competition and ‘virtuous cycles’

BioPharma Drive: Drug Pricing

Showing reporters and industry veterans a demonstration of its new drug development software, Recursion said at J.P. Morgan it is now licensing its work to buyers.

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More than skin deep: A molecular look at the mechanisms behind pigmentation variation

Science Daily: Pharmacology News

Researchers have discovered key insights into the molecular basis of skin color variations among African populations. Their findings broaden the understanding of human evolution and the genetics underpinning contemporary human skin color diversity.

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Targeting Microbiota 2024: Shaping the future of medicine – International leaders unite at the 11th World Congress

SCIENMAG: Medicine & Health

The International Society of Microbiota (ISM) is pleased to announce its 11th World Congress, Targeting Microbiota 2024. This congress is scheduled to take place on October 17-18 in Malta, and will convene international leading experts, researchers, and professionals to explore and discuss the latest advancements in the field of microbiota.

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Which pharmaceutical companies have the most drug patents in Luxembourg?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Luxembourg. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical companies have the most drug patents in Luxembourg? appeared first on DrugPatentWatch - Make Better Decisions.

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EPA finalizes TSCA SNUR for inactive PFAS

Agency IQ

The Environmental Protection Agency has finalized a Significant New Use Rule for 329 per- and polyfluoroalkyl substances (PFAS) currently designated as inactive on the Toxic Substances Control Act Inventory. Those subject to the new rule must notify and receive approval from the agency before manufacturing, importing, or processing these chemical substances for a significant new use.

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New patent expiration for Gilead Sciences drug STRIBILD

Drug Patent Watch

Annual Drug Patent Expirations for STRIBILD Stribild is a drug marketed by Gilead Sciences Inc and is included in one NDA. It is available from one supplier. There are eleven… The post New patent expiration for Gilead Sciences drug STRIBILD appeared first on DrugPatentWatch - Make Better Decisions.

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CDER’s latest novel drug approvals report shows how the pandemic is still affecting some drug approvals

Agency IQ

According to a report released this week describing CDER’s approval of 55 novel drugs in 2023, the agency failed to meet its goal dates under the Prescription Drug User Fee Act (PDUFA) Commitment Letter for 11% of applications – a record high. Here, AgencyIQ analyzes the root causes of these delays, and whether a trend could emerge in the coming years.

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New patent expiration for Gilead drug TRUVADA

Drug Patent Watch

Annual Drug Patent Expirations for TRUVADA Truvada is a drug marketed by Gilead and is included in one NDA. It is available from one supplier. There are four patents protecting… The post New patent expiration for Gilead drug TRUVADA appeared first on DrugPatentWatch - Make Better Decisions.

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New roadmap sets out U.K. device regulation timelines

Agency IQ

To kick off 2024, the British device regulator offered its medical device and IVD plans for this year and next, promising public action on the post-market surveillance regulation by mid-2024 and on the core regulations in late 2024 or early 2025. Stakeholders need to be prepared to incorporate the new requirements into their systems, though the regulator does promise there will be a transition period, similar to what the E.U. has done.

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New patent expiration for Gilead Sciences drug COMPLERA

Drug Patent Watch

Annual Drug Patent Expirations for COMPLERA Complera is a drug marketed by Gilead Sciences Inc and is included in one NDA. It is available from one supplier. There are eight… The post New patent expiration for Gilead Sciences drug COMPLERA appeared first on DrugPatentWatch - Make Better Decisions.

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EPA issues new chemicals decision framework to assess eye irritation and corrosion

Agency IQ

The EPA has issued a decision framework to be used when assessing eye irritation and corrosion hazards for new chemicals under the Toxic Substances Control Act. The framework supports EPA’s mandate to develop and implement alternative test methods and strategies, or new approach methodologies (NAMs), that do not require vertebrate animal testing for assessing risk of injury to health or the environment.

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New patent expiration for Gilead Sciences drug ATRIPLA

Drug Patent Watch

Annual Drug Patent Expirations for ATRIPLA Atripla is a drug marketed by Gilead Sciences and is included in one NDA. It is available from one supplier. There are seven patents… The post New patent expiration for Gilead Sciences drug ATRIPLA appeared first on DrugPatentWatch - Make Better Decisions.

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