Tue.Oct 03, 2023

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WHO recommends cost-effective and easily deployable malaria vaccine

Drug Discovery World

The R21/Matrix-M malaria vaccine has been recommended for use by the World Health Organization’s Strategic Advisory Group of Experts (SAGE) and the Malaria Policy Advisory Group (MPAG). Developed by The University of Oxford and the Serum Institute of India, leveraging Novavax’s adjuvant technology, R21/Matrix-M malaria vaccine demonstrates high efficacy with a reassuring safety profile.

Vaccine 148
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Broad Clinical Labs established to expand clinical services

Broad Institute

Broad Clinical Labs established to expand clinical services By Leah Eisenstadt October 3, 2023 Breadcrumb Home Broad Clinical Labs established to expand clinical services Formerly the Clinical Research Sequencing Platform, the cutting-edge laboratory at the Broad Institute is poised to further accelerate clinical genomics. By Broad Communications October 3, 2023 The Broad's Clinical Research Sequencing Platform is now Broad Clinical Labs.

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Guide to using AAV vectors in gene therapy

Drug Discovery World

Earlier this year, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. The event aimed to help the audience understand the AAV workflow, from upstream methods for AAV production and validation to downstream analysis of the packaged product for enhanced therapeutic development.

Therapies 130
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Empowering patients: How to match to clinical trials

Antidote

Clinical trials are an integral part of the medical industry, as they are required for any new treatment to be approved. Every medicine used today, whether prescription or over the counter, is a result of the rigorous research process that is a clinical trial — and for these trials to take place, volunteers are vital.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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FDA pilot programme to boost rare disease therapies

Drug Discovery World

The US Food and Drug Administration (FDA) has announced a pilot programme with the aim of accelerating the development of novel drug and biological products for rare diseases. The agency is inviting a limited number of sponsors to participate in the programme, which allows for more frequent communication with FDA staff to address clinical development issues.

FDA 130
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How to Implement Schema.org in Sitecore

Perficient: Drug Development

In this blog, we will be discussing Schema.org, the role of schema.org in SEO, and how to implement Schema.org in Sitecore. What is Schema.org? Schema.org is a universal way to describe web pages with structured data. Search engines use this information to enrich the user experience on their search results and generate rich snippets. Structured data can impact Organic impressions, CTR, and keyword ranking.

More Trending

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An Introduction to Adenovirus

addgene Blog

In April 2022, physicians in Scotland began noticing unusual cases of acute hepatitis in the pediatric population. Once ~400 cases had amassed in places around the world, hypotheses began to develop that this illness was caused by either SARS-CoV-2, Adenovirus type 41 (AdV-41), or Adenovirus-Associated Virus type 2 (AAV2) – or some unprecedented combination of the three (Servellita et al., 2023).

Virus 110
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Streamline your drug development pathway

Drug Discovery World

In pharmaceutical development, collaborating with multiple Contract Development and Manufacturing Organisations (CDMOs) and Contract Research Organisations (CROs) poses potential hurdles – from poor communication to delays, errors, and inconsistent feedback during the progression from preclinical to formulation optimisation and clinical trials. Download this SGS guide to discover: How to collaborate in the fast-paced world of drug development The current challenges of working with different CDMO

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Instant evolution: AI designs new robot from scratch in seconds

Science Daily: Pharmacology News

Researchers developed the first AI to date that can intelligently design robots from scratch by compressing billions of years of evolution into mere seconds. It's not only fast but also runs on a lightweight computer and designs wholly novel structures from scratch — without human-labeled, bias-filled datasets.

Research 110
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Latest Guide: Streamline your drug development pathway

Drug Discovery World

In pharmaceutical development, collaborating with multiple Contract Development and Manufacturing Organisations (CDMOs) and Contract Research Organisations (CROs) poses potential hurdles – from poor communication to delays, errors, and inconsistent feedback during the progression from preclinical to formulation optimisation and clinical trials. Download this new guide from SGS to discover: How to collaborate in the fast-paced world of drug development The current challenges of working with diffe

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Lilly to enter radiopharmaceutical drug field with $1.4B Point buyout

BioPharma Drive: Drug Pricing

The deal will hand Lilly a pipeline of experimental radioligand therapies, including a potential rival to Novartis’ Pluvicto, as well as a valuable manufacturing plant.

Therapies 102
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Key benefits and latest innovations in AI and lab automation

Drug Discovery World

Hosted by DDW and co-sponsored by Benchling and Proscia, “AI and Lab Automation: What are the key benefits and latest innovations?” will be free to attend on 10 October at 7AM PDT / 10AM EST / 3PM BST / 4PM CET. Join this free webinar to learn about the key benefits and latest innovations to be aware of in AI and lab automation. In his presentation, Jeremy Skillington will speak about how Poolbeg Pharma has yielded significant breakthroughs in its AI-led programmes targeting influenza and RSV us

Trials 130
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Artificial intelligence model revolutionises breast cancer surgery

Drug Target Review

A collaboration between the University of North Carolina’s Department of Surgery, the Joint UNC-NCSU Department of Biomedical Engineering, and the UNC Lineberger Comprehensive Cancer Center has given birth to an AI model capable of determining whether cancerous tissue has been completely excised during breast cancer surgery. Their remarkable findings were recently published in the prestigious Annals of Surgical Oncology.

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Regeneron, Intellia target neurological diseases in expanded gene editing deal

BioPharma Drive: Drug Pricing

The longtime partners believe that, by combining their technologies, they can create “in vivo” genetic medicines for nervous system and muscular disorders.

Disease 104
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Four Crucial Questions about the Humira Biosimilar Price War (rerun)

Drug Channels

This week, I’m rerunning some popular posts while I put the finishing touches on our new 2023-24 Economic Report on Pharmaceutical Wholesalers and Specialty Distributors. Since I published the article below in July 2023 , there have been three notable market develpoments: IQVIA has reported that as as of mid-2023, there was almost no adoption of Amgen's Amjevita, the first Humira biosimilar.

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A prehistoric cosmic airburst preceded the advent of agriculture in the Levant

Science Daily: Pharmacology News

Agriculture in Syria started with a bang 12,800 years ago as a fragmented comet slammed into the Earth’s atmosphere. The explosion and subsequent environmental changes forced hunter-gatherers in the prehistoric settlement of Abu Hureyra to adopt agricultural practices to boost their chances for survival.

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Announcing Ideas Matter

Codon

Words are the best way to turn ideas to realities. Writing on the internet helped Dan Goodwin raise millions to launch a climate biotechnology nonprofit. One-off blogs have formed the ideological basis of startup companies. The Not Boring blog grew to 60,000 subscribers and then raised $8 million to launch a venture fund. An article in STAT (which Sharon Begley spent more than a year reporting) about an “Alzheimer’s cabal” questioned, and then shifted, the priorities of a resea

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Drug Discovery Industry Roundup with Barry Bunin — October 3, 2023

Collaborative Drug

Drug Discovery Industry Roundup with Barry Bunin — October 3, 2023 The New York Times coverage of the Nobel Prize in Physiology or Medicine being awarded.

Drugs 89
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Large mound structures on Kuiper belt object Arrokoth may have common origin

Science Daily: Pharmacology News

A new study posits that the large, approximately 5-kilometer-long mounds that dominate the appearance of the larger lobe of the pristine Kuiper Belt object Arrokoth are similar enough to suggest a common origin. The study suggests that these “building blocks” could guide further work on planetesimal formational models.

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How biotech IPOs performed in the third quarter

BioPharma Drive: Drug Pricing

Only two of the eight biotech companies that priced offerings since July 1 trade at or above their debut share price, according to data from BioPharma Dive.

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Study quantifies satellite brightness, challenges ground-based astronomy

Science Daily: Pharmacology News

The ability to have access to the Internet or use a mobile phone anywhere in the world is taken more and more for granted, but the brightness of Internet and telecommunications satellites that enable global communications networks could pose problems for ground-based astronomy. Scientists confirm that recently deployed satellites are as bright as stars seen by the unaided eye.

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New patent for Cody Labs drug NUMBRINO

Drug Patent Watch

Annual Drug Patent Expirations for NUMBRINO Numbrino is a drug marketed by Cody Labs Inc and is included in one NDA. It is available from one supplier. The generic ingredient… The post New patent for Cody Labs drug NUMBRINO appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 59
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Bursts of star formation explain mysterious brightness at cosmic dawn

Science Daily: Pharmacology News

In the James Webb Space Telescope’s (JWST) first images of the universe’s earliest galaxies, the young galaxies appear too bright, too massive and too mature to have formed so soon after the Big Bang. Using new simulations, a team of astrophysicists now has discovered that these galaxies likely are not so massive after all. Although a galaxy’s brightness is typically determined by its mass, the new findings suggest that less massive galaxies can glow just as brightly from irregular, brilliant bu

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Announcing Ideas Matter

Codon

Words are the best way to turn ideas to realities. Writing on the internet helped Dan Goodwin raise millions to launch a climate biotechnology nonprofit. One-off blogs have formed the ideological basis of startup companies. The Not Boring blog grew to 60,000 subscribers and then raised $8 million to launch a venture fund. An article in STAT (which Sharon Begley spent more than a year reporting) about an “Alzheimer’s cabal” questioned, and then shifted, the priorities of a resea

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Q&A: Broad’s newly renamed clinical lab marks a turning point for the institute’s Genomics Platform

Broad Institute

Q&A: Broad’s newly renamed clinical lab marks a turning point for the institute’s Genomics Platform By Leah Eisenstadt October 3, 2023 Breadcrumb Home Q&A: Broad’s newly renamed clinical lab marks a turning point for the institute’s Genomics Platform Niall Lennon of the Genomics Platform explains how the new name, Broad Clinical Labs, reflects how genomics is becoming more clinical.

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Addressing Hidden Patient Populations During Clinical Trials Using Predictive Intelligence

Fierce BioTech

Addressing Hidden Patient Populations During Clinical Trials Using Predictive Intelligence By directly engaging with physicians and their care teams, researchers are better positioned to find the right patients – and build a cohort more representative of the general population. Download here! jsabatino Tue, 10/03/2023 - 17:10 By directly engaging with physicians and their care teams, researchers are better positioned to find the right patients – and build a cohort more representative of the gene

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Apple vs Meta: The Illusion of Privacy

Perficient: Drug Development

Apple vs Meta: The Illusion of Privacy I recently saw the buzz around the new Threads app, Its an, Meta’s new text, video, image sharing app which gained millions of subscribers within a few hours of launch. The onboarding was so simple that… I started to mindlessly tap “Next” until… I noticed a weird step They say “How Threads works”, but… How Thread Works: It’s almost as if they did not really want me to read “how it works” In fact the

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Equitable Clinical Trial Access for Women & Minorities

Fierce BioTech

Equitable Clinical Trial Access for Women & Minorities The underrepresentation of women and minority groups in clinical trials remains a pressing concern. Discover how a top 10 pharma company is making strides in addressing this disparity by harnessing the power of H1's diversity insights to build an equitable clinical trial for cardiovascular disease.

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Perficient Expands Executive Leadership Team

Perficient: Drug Development

We are proud to announce the expansion of our executive leadership team with the promotion of seven colleagues to senior vice president – Susan Adomite, Bill Davis, Ed Hoffman, Hari Madamalla, Santhosh Nair, Patrick Schwierking, and Kevin Sheen. The announcement comes just days after Tom Hogan assumed the role of Perficient’s Chief Executive Officer on Oct. 1, 2023.

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J&J, retreating from infectious disease, partners with Sanofi on E. coli vaccine

BioPharma Drive: Drug Pricing

The French vaccine giant will pay J&J $175 million to share rights to the experimental inoculation, which is currently in Phase 3 testing.

Vaccine 57
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Physician Blogs: How to Position Your Physicians as Thought-Leaders

Perficient: Drug Development

When people need to find a doctor, most of them turn to the internet. That means your organization’s physicians must find ways to stand out in this hyper-connected, hyper-competitive marketplace. As a healthcare marketer, you’re in a unique position to help your physicians find their voice. Physician blogs are a great way to get your physicians’ messages out to the public.

Doctors 52
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Unique voice print in parrots

Science Daily: Pharmacology News

Individual voice could help birds be recognized in a flock, no matter what they say.

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Despite increasing rates of tuberculosis in prisons across the globe, current WHO TB prevention guidelines fail to reach incarcerated populations

SCIENMAG: Medicine & Health

Despite increasing rates of tuberculosis in prisons across the globe, current WHO TB prevention guidelines fail to reach incarcerated populations. Programs should instead prioritize them, argue a group of researchers from Stanford, Harvard, UCL and a range of other global institutions. Credit: Jason Andrews (CC-BY 4.

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Which pharmaceutical companies have the most solution dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most solution dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most solution dosed drugs… The post Which pharmaceutical companies have the most solution dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.