Science Daily: Pharmacology News
JANUARY 26, 2024
Compared to robots, human bodies are flexible, capable of fine movements, and can convert energy efficiently into movement. Drawing inspiration from human gait, researchers from Japan crafted a two-legged biohybrid robot by combining muscle tissues and artificial materials. This method allows the robot to walk and pivot.
ASPET
JANUARY 26, 2024
Neuropathic pain is a pressing unmet medical need requiring novel non-opioid based therapeutic approaches. Using unbiased transcriptomic analysis, we found that the expression of Gpr31 , a G protein-coupled receptor, increased in the dorsal horn of the spinal cord in rats with traumatic nerve injury-induced neuropathic pain. Daily intrathecal injections of si Gpr31 reversed behavioral hypersensitivities in a time-dependent manner.
Antidote
JANUARY 26, 2024
Colorectal cancer (often shortened simply to colon cancer) is the fourth-most commonly diagnosed cancer in the United States, and it is estimated that around 150,000 Americans are diagnosed each year. While the average age of diagnosis is 66, young adults are getting diagnosed in higher numbers every year, and researchers are still unsure as to why.
Science Daily: Pharmacology News
JANUARY 26, 2024
An interdisciplinary team of researchers has developed a soft implantable device with dozens of sensors that can record single-neuron activity in the brain stably for months.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drug Target Review
JANUARY 26, 2024
Researchers from Columbia University and the US Department of Energy (DOE)’s Brookhaven National Laboratory have elucidated a method to produce large quantities of the receptor that the SARS-CoV-2 spike protein uses to bind to the surface of human cells. Coronaviruses use the homotrimeric spike glycoprotein, comprising a S1 subunit and S2 subunit in each spike monomer, on the envelope to bind to their cellular receptors.
Science Daily: Pharmacology News
JANUARY 26, 2024
Ground-penetrating radar on board NASA's Mars Perseverance rover has confirmed that the Jezero Crater, formed by an ancient meteor impact just north of the Martian equator, once harbored a vast lake and river delta. Over eons, sediment deposition and erosion within the crater shaped the geologic formations visible on the surface today. The discovery of lake sediments reinforces the hope that traces of life might be found in soil and rock samples collected by Perseverance.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
JANUARY 26, 2024
A new study found that graphene derived from metallurgical coke, a coal-based product, through flash Joule heating could serve not only as a reinforcing additive in cement but also as a replacement for sand in concrete.
Drugs.com
JANUARY 26, 2024
FRIDAY, Jan. 26, 2024 -- Too many American tourists looking for cheap cosmetic surgeries alongside their beach time are winding up dead in the Dominican Republic, a new report finds. Between 2009 and 2022, 93 people -- almost all young or.
SCIENMAG: Medicine & Health
JANUARY 26, 2024
Researchers in the RIKEN Center for Brain Science (CBS) examined the genetics of autism spectrum disorder (ASD) by analyzing mutations in the genomes of individuals and their families. They discovered that a special kind of genetic mutation works differently from typical mutations in how it contributes to the condition.
Drugs.com
JANUARY 26, 2024
FRIDAY, Jan. 26, 2024 -- “Stay in school” slogans tend to focus on the money, status and freedom that more education can provide.Now there’s another argument for getting as many degrees as you can -- having a longer life.The higher a.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
SCIENMAG: Medicine & Health
JANUARY 26, 2024
About 55 million people worldwide are living with dementia, according to the World Health Organization. The most common form is Alzheimer’s disease, an incurable condition that causes brain function to deteriorate. Credit: Courtesy University of Texas at Arlington About 55 million people worldwide are living with dementia, according to the World Health Organization.
Drugs.com
JANUARY 26, 2024
FRIDAY, Jan. 26, 2024 -- Women in poorer areas of the United States have experienced a dramatic increase in advanced cervical cancer, a new study shows.Late-stage cervical cancer cases and deaths have gone up in U.S. counties with an average.
Science Daily: Pharmacology News
JANUARY 26, 2024
TOI-1136, a dwarf star located more than 270 light years from Earth, is host to six confirmed exoplanets and a seventh as yet unconfirmed candidate. The system has provided a rich source of information on planet formation and evolution in a young solar system. Researchers used a variety of tools to compile radial velocity and transit timing variation readings to derive highly precise measurements of the exoplants' masses, orbital information and atmospheres.
Drugs.com
JANUARY 26, 2024
FRIDAY, Jan. 26, 2024 -- It’s long been thought that it takes more time for a woman to recover from a concussion than a man.But a new national study of U.S. college athletes refutes that notion, finding that women and men recover from.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
SCIENMAG: Medicine & Health
JANUARY 26, 2024
This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People’s Hospital). Credit: ©Science China Press This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People’s Hospital).
Drugs.com
JANUARY 26, 2024
FRIDAY, Jan. 26, 2024 -- If your preteen or teen skips school activities and social events, it may be more than the typically moody behavior of adolescence, new research warns.Being socially withdrawn and having physical discomforts such as.
Cytel
JANUARY 26, 2024
Innovations in the process of designing adaptive clinical trials have unlocked new possibilities for designing and executing more efficient, cost-effective, and ethical clinical trials. As more adaptive methods are introduced, biostatisticians struggle to optimize the growing number of interdependent trial parameters and ensure control over various execution assumptions.
Drugs.com
JANUARY 26, 2024
FRIDAY, Jan. 26, 2024 -- Exposure to toxic heavy metals could cause middle-aged women to have more health problems as they grow older, a new study finds.The study links toxic metal exposure to women having fewer eggs in their ovaries as they.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
JANUARY 26, 2024
Physicists discovered stars near the edge of the Milky Way travel more slowly than those closer to its center -- a surprise suggesting our galaxy's gravitational core may have less dark matter than previously thought.
Drugs.com
JANUARY 26, 2024
FRIDAY, Jan. 26, 2024 -- The old saying “feed a cold, starve a fever” is baloney, doctors say.People fighting off a seasonal respiratory virus need adequate nutrition, regardless of their symptoms, according to advice from the Baylor College of.
SCIENMAG: Medicine & Health
JANUARY 26, 2024
Traumatic brain injury (TBI) and ischemic stroke are major public health concerns and leading causes of death and disability worldwide.
BioPharma Drive: Drug Pricing
JANUARY 26, 2024
The EMA’s drugs committee again recommended rescinding an OK for Translarna, which was cleared in 2014 despite questions about its benefit.
SCIENMAG: Medicine & Health
JANUARY 26, 2024
To improve the care coordination competency of nurses involved in the management of critically ill patients on life support, an electronic app—NCCCS—was developed by Associate Professor Chie Takiguchi of Toho University and Professor Tomoko Inoue of International University of Health and Welfare. Credit: Dr.
Perficient: Drug Development
JANUARY 26, 2024
In today’s rapidly evolving digital landscape, the promise of Generative Artificial Intelligence (GenAI) looms large, offering enticing opportunities for innovation, efficiency, and growth. However, alongside its transformative potential, AI brings with it a host of complexities and challenges that can give even the most seasoned executives pause.
Agency IQ
JANUARY 26, 2024
As drug shortages have made headlines over the past few years, the FDA has announced the extension of expiration dates on a variety of drug products. And just last week, the agency announced an extended expiration date for the opioid reversal agent, Narcan. Though regulations guide some aspects of how expiration dates are determined, the agency has but limited power to extend those dates unilaterally.
thought leadership
JANUARY 26, 2024
The FDA's Biologics License Application (BLA) approvals in 2023 have marked a significant chapter in medical innovation, embodying precision and transformative therapies. A closer examination of the approvals, their numbers, and the trends they reveal unveils a dynamic landscape in biologics.
Agency IQ
JANUARY 26, 2024
MICHAL FREEDHOFF, assistant administrator of the Office of Chemical Safety and Pollution Prevention, testified in front of the Senate Environment and Public Works Committee on January 24, 2024. The assistant administrator faced a variety of positive and negative questions from senators on both sides of the aisle. Fill out the form to read the full article.
NIOSH Science Blog: Drugs
JANUARY 26, 2024
The importance of developing a tracking system for occupational fatalities, injuries and illnesses was recognized in the original Occupational Safety and Health (OSH) Act of 1970. The Secretary of Labor at that time elected to delegate responsibility to collect, compile, and analyze occupational safety and health statistics. Despite the authority in the OSH Act to cover all workers, the Bureau of Labor Statistics (BLS) in the Department of Labor decided to base their data collection program on a
Agency IQ
JANUARY 26, 2024
The FDA’s Center for Devices and Radiological Health (CDRH) has issued a new draft guidance specifically laying out the types of information it would want to see in pre-market submission for orthopedic devices with specific coating types. The guidance appears to be explaining current review processes, rather than updating the agency’s existing policies; once finalized it would supersede a guidance from 1995.
Sygnature Discovery
JANUARY 26, 2024
Here at Sygnature Discovery, we offer specialised expertise in early-stage drug formulation. Leveraging years of experience, we efficiently advance your compounds through preclinical studies and reduce risks as you move into clinical development. Our talented team of scientists can assist you in crafting robust pre-clinical development strategies. These strategies are tailored to the unique characteristics of each individual Active Pharmaceutical Ingredient (API).
Agency IQ
JANUARY 26, 2024
As many have been expecting, the Commission just proposed a second extension to the transitional period of the European IVD regulation, in response to manufacturer data showing marked unpreparedness, along with continued delays in rolling out tools like EUDAMED that are needed to implement the regulation. But medical device manufacturers also need to take a look at the proposal, since it would affect them, too.
Sygnature Discovery
JANUARY 26, 2024
In today’s pharmaceutical landscape, poorly soluble and/or permeable compounds are common challenges. Our team excels in developing formulations that address these issues, enhancing bioavailability and stability for your candidate compound. With our combined expertise in solid form and formulation, we aim to significantly de-risk your molecule, paving the way for successful clinical drug product formulation.
Agency IQ
JANUARY 26, 2024
The Environmental Protection Agency has released its draft Scientific Integrity Plan that lays out a grand plan for preserving scientific integrity at the agency. The agency’s goals, however, conflict with the actual enforceability of the policy going forward. Fill out the form to read the full article.
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