Mon.Jul 22, 2024

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Smell of human stress affects dogs' emotions leading them to make more pessimistic choices

Science Daily: Pharmacology News

Dogs experience emotional contagion from the smell of human stress, leading them to make more 'pessimistic' choices, new research finds. Researchers tested how human stress odors affect dogs' learning and emotional state.

Research 131
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Ionis plots next steps for Angelman drug Biogen passed on

BioPharma Drive: Drug Pricing

The company plans to start a late-stage study next year, after a smaller trial found its drug offered “robust and consistent” benefits on communication, cognition and motor function.

Drugs 117
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Chimpanzees gesture back and forth quickly like in human conversations

Science Daily: Pharmacology News

When people are having a conversation, they rapidly take turns speaking and sometimes even interrupt. Now, researchers who have collected the largest ever dataset of chimpanzee 'conversations' have found that they communicate back and forth using gestures following the same rapid-fire pattern.

Research 129
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Daily Supplements May Slow 'Dry' Form of Macular Degeneration

Drugs.com

MONDAY, July 22, 2024 -- Daily supplements can slow loss of vision related to late-stage “dry” age-related macular degeneration (AMD), a new study finds.The rate of dry AMD progression into a key eye region slowed by about 55% over an average three.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Breakthrough in skeletal muscle regeneration

Science Daily: Pharmacology News

In a finding that opens the door to the development of targeted therapies for various muscle disorders, newly published research identifies key mechanisms of skeletal muscle regeneration and growth of muscles following resistance exercise.

Therapies 128
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CDC Warns of Listeria Outbreak Tied to Deli Meats

Drugs.com

MONDAY, July 22, 2024 -- At least 28 people have been hospitalized and two have died in a multi-state outbreak of listeria linked to deli meat, U.S. health officials warned.In an investigation notice posted Friday, the U.S. Centers for Disease.

Hospitals 111

More Trending

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Scientists May Have Stopped a Form of Inherited Blindness in Dogs

Drugs.com

MONDAY, July 22, 2024 -- In her youth, Shola, an English Shepherd Dog, was a member of the Edale Mountain Rescue Team, a corps of U.K. pooches charged with helping hurt and stranded hikers. But Shola was retired as part of the Rescue Team after a.

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Are AI-chatbots suitable for hospitals?

Science Daily: Pharmacology News

Large language models may pass medical exams with flying colors but using them for diagnoses would currently be grossly negligent. Medical chatbots make hasty diagnoses, do not adhere to guidelines, and would put patients' lives at risk. A team has systematically investigated whether this form of artificial intelligence (AI) would be suitable for everyday clinical practice.

Hospitals 124
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Dogs Can Smell Your Stress and Make Choices Based on It

Drugs.com

MONDAY, July 22, 2024 -- Dogs can sniff out whether a human is stressed or relaxed, new research suggests, and that sensory feedback appears to influence canine emotions and choices.The dog doesn't even have to know the human well to interpret odor.

Research 105
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Deep-ocean floor produces its own oxygen

Science Daily: Pharmacology News

An international team of researchers has discovered that metallic minerals on the deep-ocean floor produce oxygen -- 13,000 feet below the surface. Discovery challenges long-held assumptions that only photosynthetic organisms generate Earth's oxygen. Minerals at the abyssal seafloor appear to act like geobatteries to produce oxygen in a process that does not require sunlight.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Money Worries Keep Depressed Americans From Mental Health Care

Drugs.com

MONDAY, July 22, 2024 -- Medical debt is significantly more common among people with a mood disorder, and these money woes can keep them from getting the help they need, a new study says.Among people with depression or anxiety, those with medical.

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An over- or under-synchronized brain may predict psychosis

Science Daily: Pharmacology News

Is it possible to assess an individual's risk of psychosis? Identifying predictive markers is a key challenge in psychiatry. A team now shows that overly strong or weak interconnections between certain brain areas could be a predictive marker of the disease.

Disease 117
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The Role of Data Monitoring Committees (DMC) in Clinical Trials

Quanticate

Throughout the conduct of a clinical trial, ensuring patient safety and maintaining the integrity of the study are vital. This is where, Data Monitoring Committees (DMC) are used to support patient safety and integrity.

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Development of 'living robots' needs regulation and public debate

Science Daily: Pharmacology News

Researchers are calling for regulation to guide the responsible and ethical development of bio-hybrid robotics -- a ground-breaking science which fuses artificial components with living tissue and cells.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Two More Bird Flu Cases Reported in Colorado Poultry Workers

Drugs.com

MONDAY, July 22, 2024 -- Two more cases of bird flu have been reported in Colorado poultry workers, but reassuring research finds the virus doesn't seem to be fueling silent infections, U.S. health officials report.The two additional H5N1 avian flu.

Virus 104
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Astrophysicists uncover supermassive blackhole/dark matter connection in solving the 'final parsec problem'

Science Daily: Pharmacology News

Researchers have found a link between some of the largest and smallest objects in the cosmos: supermassive black holes and dark matter particles. Their new calculations reveal that pairs of supermassive black holes (SMBHs) can merge into a single larger black hole because of previously overlooked behavior of dark matter particles, proposing a solution to the longstanding 'final parsec problem' in astronomy.

Research 114
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As Days Heat Up, More Seniors Skip Doc Appointments

Drugs.com

MONDAY, July 22, 2024 -- More folks, especially seniors, are missing doctors’ appointments due to extreme weather, a new study shows.The rate of missed primary care appointments increases 0.64% for every 1-degree increase in temperatures 90 degrees.

Doctors 103
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Converting captured carbon to fuel: Study assesses what's practical and what's not

Science Daily: Pharmacology News

A new analysis sheds light on major shortfalls of a recently proposed approach to capture CO2 from air and directly convert it to fuel using electricity. The authors also provide a new, more sustainable, alternative.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Private biotech M&A surges amid difficult IPO market

BioPharma Drive: Drug Pricing

Private biotech company acquisitions are on their fastest pace in years, a trend some in the industry say is driven by the abundance of mature, but not yet public, drug startups.

Marketing 101
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Scientists use AI to predict a wildfire's next move

Science Daily: Pharmacology News

Researchers have developed a new model that combines generative AI and satellite data to accurately forecast wildfire spread.

Research 121
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To address the fentanyl crisis, greater access to methadone Is needed

National Institute on Drug Abuse: Nora's Blog

To address the fentanyl crisis, greater access to methadone Is needed area Mon, 07/22/2024 - 12:43 Nora's Blog July 29, 2024 By Nora D. Volkow, National Institute on Drug Abuse Image ©Getty images/ seb_ra Over the past several years, the increasing prevalence of fentanyl in the drug supply has created an unprecedented overdose death rate and other devastating consequences.

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Team develops safe and long-cyclable lithium metal battery for high temperatures

Science Daily: Pharmacology News

In recent years, batteries have become ubiquitous in consumers' daily lives. However, existing commercial battery technologies, which use liquid electrolytes and carbonaceous anodes, have certain drawbacks such as safety concerns, limited lifespan, and inadequate power density particularly at high temperatures.

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Breakthroughs in immunotherapy: glycoproteins as predictive biomarkers for therapeutic response

BioPharma Drive: Drug Pricing

Serum-based glycoproteins demonstrate success in predicting immune checkpoint inhibitor therapy outcomes.

Therapies 111
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Controlling mosquito populations through genetic breeding

Science Daily: Pharmacology News

Researchers have found a new way to identify genetic targets useful for control of mosquito populations, potentially offering an alternative to insecticides. Their study focused on the genetic basis of species incompatibility. They crossed Ae. aegypti, a major global arboviral disease vector, and its sibling species, Ae. mascarensis, from the Indian Ocean.

Disease 80
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Drug Discovery Industry Roundup with Barry Bunin — July, 22 2024

Collaborative Drug

How A.I. Is Revolutionizing Drug Development. Holy Grail for Weight-Loss Drugs Is Sleep Apnea? DNA Discovery that Could Help Find Pancreatic Cancer Cure.

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US government declines to clear Bluebird fertility support for Zynteglo patients

BioPharma Drive: Drug Pricing

The Health and Human Services' inspector general issued a "negative opinion" on Bluebird's request one week after Vertex sued the federal government over access to fertility preservation services.

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Cracking the Biosimilar Code: A Deep Dive into Effective IP Strategies

Drug Patent Watch

In the rapidly evolving landscape of biosimilars, intellectual property (IP) strategy is paramount.

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Birds need entertainment during avian flu lockdowns

Science Daily: Pharmacology News

Birds need varied activities during avian flu lockdowns, new research shows.

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Halfway there: Novel drug approvals and their supportive clinical trials so far in 2024

Agency IQ

BY AMANDA CONTI In the first half of 2024, the FDA’s Center for Drug Evaluation and Research (CDER) approved 21 novel drug products. AgencyIQ has analyzed those approvals, revealing the extent to which FDA is approving products reliant upon just a single pivotal trial – and in some cases, trials with remarkably little racial or ethnic diversity. AgencyIQ reviews drug approvals from the Center for Drug Evaluation and Research (CDER) and the Center for Biologics Evaluation and Research (CBER).

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Male elephants signal 'let's go' with deep rumbles

Science Daily: Pharmacology News

Male elephants use infrasonic rumbles to signal group departures, revealing complex vocal coordination and strong social bonds.

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The 103 regulations the EPA is currently working on

Agency IQ

BY WALKER LIVINGSTON, ESQ On July 5, 2024, the EPA published its Spring 2024 Unified Agenda, which reveals what regulations the agency is planning on releasing by the end of the year and beyond. The document mostly contains information that has already been released in previous editions, with a few interesting updates – and many updated release timelines.

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Common Sickle Cell Drug, Hydroxyurea, Won't Harm Female Fertility

Drugs.com

MONDAY, July 22, 2024 -- A drug called hydroxyurea has long been used to fight sickle cell disease, but some female patients may have shied away from it due to concerns that it could harm future fertility. Those fears may be unfounded: A new study.

Drugs 59
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Facing headwinds, FDA moves ahead on diagnostics policy implementation but faces Congressional, legal, and judicial questions

Agency IQ

BY LAURA DIANGELO, MPH In April 2024, the FDA issued a final rule to update its regulatory approach to certain test products known as Laboratory Developed Tests (LDTs). While the agency has been working to implement its rule, which has broad-reaching impacts for diagnostics and drug developers, other moves by the Supreme Court and legislators could impact the agency’s next steps.

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