Tue.Sep 26, 2023

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Webinar: How AI is transforming drug discovery

Drug Discovery World

This webinar supported by Thermo Fisher Scientific and presented by Generate:Biomedicines will be free to attend on 12 October 9am EDT / 2pm BST / 3pm CEST. The webinar, hosted by DDW, will feature the expertise of Adam Root, Vice President, Protein Sciences at Generate:Biomedicines who will discuss how an integrated approach of using Cryo-EM with ML methods has the capability to program novel proteins which holds promise for bringing new medicines to patients faster, cheaper, and better tailore

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Common Plastics Chemical Tied to Higher Odds for Postpartum Depression

Drugs.com

TUESDAY, Sept. 26, 2023 -- Moms with higher prenatal levels of plastics chemicals known as phthalates may face a slightly increased risk of postpartum depression, according to a new study.

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Webinar on benefits and innovation in AI and lab automation

Drug Discovery World

Hosted by DDW and co-sponsored by Benchling and Proscia, “AI and Lab Automation: What are the key benefits and latest innovations?” will be free to attend on 10 October at 7AM PDT / 10AM EST / 3PM BST / 4PM CET. Join this free webinar to learn about the key benefits and latest innovations to be aware of in AI and lab automation. In his presentation, Jeremy Skillington will speak about how Poolbeg Pharma has yielded significant breakthroughs in its AI-led programmes targeting influenza and RSV us

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Intercept, after biotech rollercoaster ride, agrees to buyout by Alfasigma

BioPharma Drive: Drug Pricing

Once valued at more than $7 billion, the liver drug company couldn’t secure a long-sought FDA approval in NASH and last month said it would abandon that research.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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AACR Cancer Progress Report with spotlight on cancer immunotherapy 

Drug Discovery World

On 13 September 2023, the American Association for Cancer Research (AACR) released the AACR Cancer Progress Report 2023: Advancing the Frontiers of Cancer Science and Medicine. This report chronicles how basic, translational, clinical cancer research, and cancer-related population sciences — supported by federal investments in the National Institutes of Health (NIH) and the National Cancer Institute (NCI)—remain vitally important to improving health and saving lives.

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Perficient Principal’s Articles on Composable Featured in CMS Wire

Perficient: Drug Development

In the ever-evolving realm of digital transformation, staying ahead of the curve is paramount. This is where Composable Architecture steps in, reshaping the way businesses construct and manage their digital landscapes. We’re excited to introduce you to two illuminating articles recently featured on CMSWire.com, “The Heart of Composable Architecture,” and “Navigating the Long Tail of Composable in the Martech Landscape” Both articles were penned by Perficient’s own

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Humans Outperform AI in Interpreting Chest X-Rays

Drugs.com

TUESDAY, Sept. 26, 2023 -- AI tools may help boost radiologists’ confidence in their diagnoses, but they can't be relied on to identify common lung diseases on chest X-rays, a new study says. Researchers pitted 72 radiologists against four.

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In depth eReport on Synthetic Biology: Is it the next big thing?

Drug Discovery World

Synthetic biology has shown significant potential to the drug discovery sector. Although not a new area of science, the prominence of this technology and its applications – evident during the Covid-19 pandemic – have increased of late. This has created advances in the development of new medicines and our ability to find solutions for unmet medical needs.

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Immunovant data show potential for autoimmune disease drug

BioPharma Drive: Drug Pricing

Much anticipated clinical trial data for Immunovant’s experimental FcRn inhibitor could catalyze business development decisions for its parent, Roivant Sciences.

Disease 109
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Teen Boys With High Blood Pressure Face Danger Decades Later

Drugs.com

TUESDAY, Sept. 26, 2023 -- Teenage boys who have high blood pressure may find themselves on the road to serious heart problems in adulthood. Swedish researchers found that boys who had high blood pressure at 18 were at risk for heart failure, heart.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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What clinical trial statistics tell us about the state of research today

Antidote

Recruiting patients for a clinical trial can be a challenging process. Studies show that many patients report having little or no knowledge of clinical trials , and sponsors and researchers often report having difficulties finding and enrolling patients in studies. However, once patients understand more about the medical research process, many individuals do want to participate in a clinical trial.

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Nurses, Health Care Staff Face Higher Suicide Risks

Drugs.com

TUESDAY, Sept. 26, 2023 -- Nurses, health technicians and health care support workers face a higher risk of suicide than the general U.S. population does, an alarming new study shows. Researchers pointed out these workers have to perform stressful.

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Decreasing biodiversity may promote spread of viruses

Science Daily: Pharmacology News

How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Researchers have now described one piece of that puzzle, showing that the destruction of tropical rainforests harms the diversity of mosquito species. At the same time, more resilient species of mosquitoes become more prevalent -- which also means the viruses they carry are more abundant.

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About 1 in 14 U.S. Adults Have Had Long COVID

Drugs.com

TUESDAY, Sept. 26, 2023 -- One in every 14 American adults has suffered from long COVID, a new federal survey has found. About 7% of adults have ever had long COVID and more than 3% still have it, according to the 2022 National Health Interview.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Study sheds new light on strange lava worlds

Science Daily: Pharmacology News

In a new study, scientists have shown that sweeping molten oceans have a large influence on the observed properties of hot rocky Super-Earths, such as their size and evolutionary path.

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Buying Marijuana Online Easy for Minors, Study Finds

Drugs.com

TUESDAY, Sept. 26, 2023 – The lax enforcement of age limits by many online marijuana dispensaries makes it easier for minors to buy weed, claims new research that looked at online weed sales in 32 states. “It is imperative to require strict.

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How to be an excellent trainee

addgene Blog

We’ve all either been there or are going to be there – undergraduate students, rotation students, joining a new lab at any career stage, learning a new technique while visiting a lab, or maybe even training on a new technique with a coworker. Being a new trainee (even if you ’ re an oldbe trainee!) can be pretty nerve-wracking. So how can you be the best trainee possible?

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Blood Tests for Long COVID Could Lead to Better Treatments

Drugs.com

TUESDAY, Sept. 26, 2023 -- People who develop long COVID have distinct abnormalities in their immune and hormonal function that can be picked up with blood tests, researchers have found.

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The Trust Fall: Building Successful & Diverse Trials Outside the U.S.

H1 Blog

Breaking Down Barriers to International Clinical Trials Global Disruptions, Health Equity & Data Sharing As the U.S. ramps up for release of the latest COVID-19 vaccine booster, the Centers for Disease Control and Prevention (CDC) recommends that all Americans aged 6 months and older receive the updated COVID booster amid rising cases and hospitalizations across the country.

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Stigma, Even Harm Common When Transgender People Meet With Doctors

Drugs.com

TUESDAY, Sept. 26, 2023 -- Transgender people have a tough time receiving adequate medical care due to issues like voyeurism, being treated as abnormal and even being denied care due to their gender identity, a new study finds. “I would say what I.

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Dreamforce Takeaways: DATA + AI + CRM for Manufacturers

Perficient: Drug Development

Dreamforce 2023 was hyper-focused on generative AI and the ways Salesforce is making it easy to take advantage of the benefits – especially for manufacturers. Oftentimes, the thought of artificial intelligence (AI) is accompanied by fears of the unknown and insecurities around data sharing. Salesforce is helping demystify those notions and build trust with the launch of Einstein 1 – bringing the power of Einstein AI into the fold of the secure CRM platform you already trust, powered by data you

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Strike a Pose: Yoga Helps Heart Failure Patients

Drugs.com

TUESDAY, Sept. 26, 2023 -- Heart failure can make everyday activities and exercise tough to carry out, but yoga might be a beneficial add-on to standard care. A new study from India finds this ancient practice improves quality of life and cardio.

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Hyman, Phelps & McNamara, P.C. Names Jeff Grizzel Chief Marketing Officer

FDA Law Blog: Biosimilars

Hyman, Phelps & McNamara, P.C. (HP&M), a leader in providing legal and regulatory support to the life sciences industries, today announced the appointment of Jeff Grizzel to the newly created position of Chief Marketing Officer (CMO). Grizzel will oversee the marketing organization, with responsibility for continuing and enhancing HP&M’s brand and expanding its business development activities.

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Keeping Baby Safe: Follow These Tips to Lower Sleep Risks

Drugs.com

TUESDAY, Sept. 26, 2023 -- It’s always a good time to check your baby’s sleep space. The U.S. Consumer Product Safety Commission (CPSC) has released its annual report on the topic, showing that risks associated with nursery products continue to.

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When data are not there, what do we do? A multi-step approach to occupational health inequity research

NIOSH Science Blog: Drugs

When we have a research question but cannot find a dataset to answer it, what should we do? This situation happens quite often in new areas of research, such as occupational health inequities. One approach is to get funding to do primary research so that you can collect the data you need to answer the research question. This is easier said than done because without some assurance that the question is worth asking (i.e.

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Novo Nordisk, Evotec partner in metabolic disease drug discovery pact

BioPharma Drive: Drug Pricing

Hunting for more metabolic disease drugs, Novo plans to work with Evotec to shape early academic research into new development programs.

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Unlocking Sales Excellence: How Personalized Learning Elevates Pharma Training ROI

ACTO

The Life Science Industry is a complex and competitive landscape where the right knowledge and the right skills can make all the difference. Organizations are constantly seeking ways to enhance field team performance. One of the most promising avenues to achieve this is through personalized learning. In this blog, we'll explore how personalized learning can significantly impact training return on investment (ROI).

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Diving Deeper into Test Case Studio’s Advanced Functionality

Perficient: Drug Development

Test Case Studio is a tool that not only simplifies the testing process but also offers a range of advanced features that elevate your testing capabilities to a new level. If you haven’t already, we recommend checking out our previous blog on “Efficient Test Case Creation with TestCase Studio”, which provides insights into how this tool streamlines test case creation.

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Patients who quit smoking after percutaneous coronary intervention do as well as non-smokers – unless they had smoked heavily

SCIENMAG: Medicine & Health

Patients who quit smoking after undergoing percutaneous coronary intervention (PCI) for narrowed arteries have similar outcomes as non-smokers during four years of follow-up after the procedure, according to a large study published in the European Heart Journal [1] today (Wednesday). However, if they had been heavy, long-term smokers, no improvement was seen.

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AI Business Strategy: Low-Cost, High benefit

Perficient: Drug Development

What should an AI business strategy be, and how should it implement AI tooling? Many entities struggle , finding cost, security, and benefits failing to square. Problems like the inability to collect and mobilize internal data, and cost/workflow hurdles with years of work hold companies back. If desiring a custom implementation leveraging the power of AI and minimizing those pitfalls, Perficient can help.

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A novel role discovered for vagus nerve

SCIENMAG: Medicine & Health

The vagus nerve, known for its role in ‘resting and digesting’, has now been found to have an important role in exercise, helping the heart pump blood, which delivers oxygen around the body.

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Unlocking Potential: Brain Training Apps for Cognitive Disabilities

Perficient: Drug Development

In today’s fast-paced world, technology has become an integral part of our lives, serving as a powerful tool for communication, entertainment, and productivity. However, it’s important to recognize that technology can also be a game-changer for individuals facing cognitive disabilities. Brain training apps, a subset of assistive technologies, have emerged as a promising solution to help individuals with cognitive disabilities enhance their cognitive abilities, improve their quality o

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Aston University research pioneers making renewable hydrogen and propane fuel gases from glycerol

SCIENMAG: Medicine & Health

Credit: Aston University’s Energy and Bioproducts Research Institute. Research shows way forward for making renewable hydrogen from glycerol Crude glycerol from biodiesel production plants cheap and abundant Could benefit the environment and reduce reliance on fuel imports.

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Empowering All Learners: Interactive Learning Tools as Assistive Technology

Perficient: Drug Development

Assistive technology has transformed the educational landscape by ensuring that individuals with disabilities have equal access to learning opportunities. Among the various forms of assistive technology, interactive learning tools stand out as versatile and powerful aids. These tools are designed to accommodate a wide range of learning styles and abilities, making education more inclusive and accessible.