Science Daily: Pharmacology News
OCTOBER 10, 2024
Researchers developed a rating system to evaluate the plausibility of climate model simulations in the IPCC's latest report, and show that models that lead to potentially catastrophic warming are to be taken seriously.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- After Hurricane Helene knocked out a North Carolina production plant for a major supplier of IV fluids for U.S. hospitals, officials said the federal government is reaching out internationally to help restore supply.The.
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Science Daily: Pharmacology News
OCTOBER 10, 2024
A new study from The Neuro (Montreal Neurological Institute-Hospital) of McGill university, the University of Ottawa and the University of Zaragoza in Spain elaborates on bilingualism's role in cognition, showing increased efficiency of communication between brain regions.
BioPharma Drive: Drug Pricing
OCTOBER 10, 2024
In a letter to Pfizer’s board, the activist investor claimed former CEO Ian Read and CFO Frank D’Amelio were pressured to abandon a Starboard-led attempt to change the company’s direction.
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Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- More than 15.5 million U.S. adults have been diagnosed with ADHD, and nearly three-quarters of those taking medication to treat it say drug shortages are hampering their ability to get help, a new report finds. According.
Science Daily: Pharmacology News
OCTOBER 10, 2024
Skin pigmentation may act as a 'sponge' for some medications, potentially influencing the speed with which active drugs reach their intended targets, a pair of scientists report.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
OCTOBER 10, 2024
When three massive objects meet in space, they influence each other through gravity in ways that evolve unpredictably. In a word: Chaos. That is the conventional understanding. Now, a researcher has discovered that such encounters often avoid chaos and instead follow regular patterns, where one of the objects is quickly expelled from the system. This new insight may prove vital for our understanding of gravitational waves and many other aspects of the universe.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- Some people might have Long COVID symptoms because the coronavirus is still active inside their bodies, a new study finds.People with wide-ranging Long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in.
Science Daily: Pharmacology News
OCTOBER 10, 2024
The world's freshwater lakes are freezing over for shorter periods of time due to climate change. This shift has major implications for human safety, as well as water quality, biodiversity, and global nutrient cycles.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- It’s never too late for a person to quit smoking, even if they’re elderly, a new study finds.Dropping the smokes even as late as 75 can meaningfully increase a person’s life expectancy, researchers reported recently in the.
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Science Daily: Pharmacology News
OCTOBER 10, 2024
Scientists have discovered a low-cost method to significantly reduce this pollution from hydrogen internal combustion engines by improving the efficiency of their catalytic converters. The researchers found that infusing platinum in catalytic converters with a highly porous material called Y zeolites greatly enhances the reactions between nitrogen oxides and hydrogen, converting unhealthful nitrogen oxides into harmless nitrogen gas and water vapor.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct.10, 2024 -- Most boys treated with breakthrough gene therapy for a rare but deadly brain illness are faring well six years later, two new reports find.The 77 boys were treated for cerebral adrenoleukodystrophy (CALD), a formerly.
Science Daily: Pharmacology News
OCTOBER 10, 2024
Chemists have developed a new chemical reaction that will allow researchers to synthesize selectively the left-handed or right-handed versions of 'mirror molecules' found in nature and assess them for potential use against cancer, infection, depression, inflammation and a host of other conditions.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- A newly developed soft robotic finger with a sophisticated sense of touch could one day help your doctor perform routine office examinations, a new study suggests.The finger can take a person’s pulse and detect abnormal l.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Patent Watch
OCTOBER 10, 2024
China has emerged as a significant player in the global generic drug active pharmaceutical ingredient (API) market. The country’s vast production capacity, low costs, and strategic location have made it an attractive destination for pharmaceutical companies seeking to source APIs.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- Attention all 'know-it-alls."Folks who are sure they're right often believe they've got enough information to make up their minds, even if in reality they only have part of the picture, a new study finds.It’s a concept c.
Science Daily: Pharmacology News
OCTOBER 10, 2024
Materials researchers have created a new composite material that combines two incompatible properties: stiff yet with a high damping capacity.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- A new study finds persistent loneliness taking a toll on aging brains and significantly raising a person's odds for dementia.Research funded by the U.S. National Institute of Mental Health tracked self-reports of.
BioPharma Drive: Drug Pricing
OCTOBER 10, 2024
Seven young boys given Bluebird's Skysona later developed blood cancers, findings that could shape how doctors balance the gene therapy’s risks against its benefit.
Science Daily: Pharmacology News
OCTOBER 10, 2024
They say that hindsight is 20/20, and though the theory of ecological speciation -- which holds that new species emerge in response to ecological changes -- seems to hold in retrospect, it has been difficult to demonstrate experimentally, until now. Biologists have identified a key connection between ecology and speciation in Darwin's finches, famous residents of the Galapagos Islands, Ecuador.
BioPharma Drive: Drug Pricing
OCTOBER 10, 2024
The offering will fund testing of a potential rival to Amgen’s Tezspire and is already the sixth for an immune drug developer this year, the most since 2021.
Science Daily: Pharmacology News
OCTOBER 10, 2024
A new solution deposition process for semiconductors yields high-performing transistors by introducing more defects, counterintuitively. Researchers used these devices to construct high- speed logic circuits and an operational high-resolution inorganic LED display.
BioPharma Drive: Drug Pricing
OCTOBER 10, 2024
Data readouts over the next six months could set expectations for how the highly lucrative market for weight loss therapies will look in the future.
Science Daily: Pharmacology News
OCTOBER 10, 2024
When lightning cracks on Earth, especially high-energy electrons may fall out of Earth's inner radiation belt, according to a new study -- an electron 'rain' that could threaten satellites, and even humans, in orbit.
BioPharma Drive: Drug Pricing
OCTOBER 10, 2024
The offering will fund testing of a potential rival to Amgen’s Tezpire and is already the sixth for an immune drug developer this year, the most since 2021.
Covalent Modifiers
OCTOBER 10, 2024
Póti, Á.L., Bálint, D., Alexa, A. et al. Nat Commun 15 , 8607 (2024). [link] For mitogen-activated protein kinases (MAPKs) a shallow surface—distinct from the substrate binding pocket—called the D(ocking)-groove governs partner protein binding. Screening of broad range of Michael acceptor compounds identified a double-activated, sterically crowded cyclohexenone moiety as a promising scaffold.
addgene Blog
OCTOBER 10, 2024
Addgene has updated our useful CRISPR guide to include PRIME editing, new enzymes, and more!
Covalent Modifiers
OCTOBER 10, 2024
Bálint, D., Póti, Á.L., Alexa, A. et al. Nat Commun 15, 8606 (2024). [link] There has been a surge of interest in covalent inhibitors for protein kinases in recent years. Despite success in oncology, the off-target reactivity of these molecules is still hampering the use of covalent warhead-based strategies. Herein, we disclose the development of precision-guided warheads to mitigate the off-target challenge.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- Inflammatory bowel conditions such as Crohn’s disease and colitis cause intense financial pressure as well as physical distress, a new study shows.More than 40% of people with inflammatory bowel disease have made s.
Drug Target Review
OCTOBER 10, 2024
What are the risks of over-reliance on healthy donor material in early-stage research, and how can decision-makers ensure a balanced integration of diseased material to avoid potential gaps when transitioning to clinical trials? Developing cell therapies exclusively with healthy donor material introduces substantial risks that can hinder clinical translation and jeopardise the entire program.
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024b -- There's a small but significant increased of certain cancers in people battling multiple sclerosis (MS), new research shows.Those malignancies include cancers of the bladder, brain and cervix, said a team from Rennes.
BioPharma Drive: Drug Pricing
OCTOBER 10, 2024
Attorneys argue Khan and two other commissioners are biased against pharmacy benefit managers and should recuse themselves from an ongoing lawsuit against the middlemen.
LifeSciVC
OCTOBER 10, 2024
By Jonathan Montagu, CEO of HotSpot Therapeutics, as part of the From The Trenches feature of LifeSciVC HotSpot’s trip to Barcelona for the recent European Society of Medical Oncology (ESMO) Annual Meeting was no ‘European Vacation,’ but it was certainly teeming with excitement. At the congress, we were thrilled to share some of the clinical data emerging from our Phase 1 program , an ongoing study evaluating our potent and selective investigational CBL-B inhibitor, HST-1011, in patients with ad
BioPharma Drive: Drug Pricing
OCTOBER 10, 2024
The FDA has authorized nearly 1,000 medical devices with artificial intelligence features as companies including GE Healthcare and Siemens Healthineers build out their AI efforts.
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