Thu.Aug 29, 2024

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Cell and gene therapy investment, once booming, is now in a slump

BioPharma Drive: Drug Pricing

Far fewer venture funding rounds were closed by cell and gene therapy developers over the first six months of 2024 than in prior years. Experts say there are several factors.

Therapies 356
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Scientists discover how starfish get 'legless'

Science Daily: Pharmacology News

Researchers have made a groundbreaking discovery about how sea stars (commonly known as starfish) manage to survive predatory attacks by shedding their own limbs. The team has identified a neurohormone responsible for triggering this remarkable feat of self-preservation.

Research 317
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First Cluster of Cases of Human Bird Flu Detected at Colorado Poultry Facilities

Drugs.com

THURSDAY, Aug. 29, 2024 (HeathDay News) -- The first known U.S. cluster of cases of bird flu in humans has been recorded at two poultry facilities in Colorado, the Centers for Disease Control and Prevention (CDC) reported Thursday.The nine infected.

Disease 290
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Study reveals crucial role of mixing Atlantic and Arctic waters in global ocean circulation

Science Daily: Pharmacology News

A new study sheds light on the vital role that the mixing of Atlantic and Arctic waters plays in sustaining the Atlantic Meridional Overturning Circulation (AMOC), which is crucial for regulating Earth's climate.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Migraine Drug Ubrelvy May Stop Headaches Before They Start

Drugs.com

THURSDAY, Aug. 29, 2024 -- A migraine drug can help stop the devastating headaches in their tracks, allowing sufferers to go about their daily lives with little to no symptoms, a new clinical trial has found.People who took ubrogepant (Ubrelvy).

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Keytruda fails lung and skin cancer trials, limiting further expansion

BioPharma Drive: Drug Pricing

The trial setbacks for Merck’s best-selling drug, which faces patent expiration in 2028, are a blow to the company’s plans for further indication expansion.

Trials 265
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Gene therapy gets a turbo boost

Science Daily: Pharmacology News

For decades, scientists have dreamt of a future where genetic diseases, such as the blood clotting disorder hemophilia, could be a thing of the past. Gene therapy, the idea of fixing faulty genes with healthy ones, has held immense promise. But a major hurdle has been finding a safe and efficient way to deliver those genes. Researchers have now made a significant breakthrough in gene editing technology that could revolutionize how we treat genetic diseases.

Therapies 309
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Six More Deaths in Listeria Outbreak Tied to Boar's Head Deli Meats

Drugs.com

THURSDAY, Aug. 29, 2024 -- The death toll from listeria linked to tainted Boar's Head deli meats has risen to nine, with six more fatalities reported Wednesday by the Centers for Disease Control and Prevention.Deaths have now occurred in Florida.

Disease 264
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New process vaporizes plastic bags and bottles, yielding gases to make new, recycled plastics

Science Daily: Pharmacology News

Chemists have developed a catalytic process that turns the largest component of today's plastic waste stream, polyolefin plastic bags and bottles, into gases -- propylene and isobutylene -- that are the building blocks of polypropylene and other types of plastics. The process uses inexpensive solid catalysts that can be scaled to industrial production, making this a potentially viable means of creating a circular economy for these throw-away plastics.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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PBM executives threatened with fines for alleged perjury in House hearing

BioPharma Drive: Drug Pricing

Testimony from the heads of Express Scripts, Optum Rx and Caremark in July defending pharmacy benefit managers’ business practices could be coming back to bite them.

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Scientist's method could give months' warning of major earthquakes

Science Daily: Pharmacology News

The public could have days or months of warning about a major earthquake through identification of prior low-level tectonic unrest over large areas, according to research by scientists who analyzed two major quakes in Alaska and California.

Research 302
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Experts Warn of Unsafe Fake Children's Car Seats Sold Online

Drugs.com

THURSDAY, Aug. 29, 2024 -- Jillian Davis was pleased to be gifted a car seat during her pregnancy, from a family member who bought it online from a major retailer.But following the delivery of her daughter in late June, a car seat tech at her Salt.

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Dancing galaxies make a monster at the cosmic dawn

Science Daily: Pharmacology News

Astronomers have spotted a pair of galaxies in the act of merging 12.8 billion years ago. The characteristics of these galaxies indicate that the merger will form a monster galaxy, one of the brightest types of objects in the Universe.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Just Cutting Down on Smoking Won't Help Your Heart, Study Finds

Drugs.com

THURSDAY, Aug. 29, 2024 -- Smokers who quit the habit soon after being diagnosed with heart disease saw their odds for heart attack or death drop by almost half over the next five years, a new report found.However, those who simply cut back on.

Disease 246
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Can fungi turn food waste into the next culinary sensation?

Science Daily: Pharmacology News

Fungi can transform plant and animal products into delicious foods like cheese, miso and beer. A researcher argues that a type of filamentous mold -- Neurospora intermedia -- could also turn food waste into culinary treats. Currently, only Indonesians have discovered this secret; they grow the mold on leftover soy pulp from making tofu to create oncom.

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Evidence Supports Classroom Cellphone Bans, Expert Says

Drugs.com

THURSDAY, Aug. 29, 2024 -- Classroom cellphone bans should help improve learning environments in schools, a child development expert says.Keeping the devices out of classrooms would help focus attention, improve problem-solving and -- by allowing.

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Researchers unveil scalable graphene technology to revolutionize battery safety and performance

Science Daily: Pharmacology News

Researchers have developed a pioneering technique for producing large-scale graphene current collectors. This breakthrough promises to significantly enhance the safety and performance of lithium-ion batteries (LIBs), addressing a critical challenge in energy storage technology.

Research 298
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Another Unwanted Gift From Climate Change: More Salmonella

Drugs.com

THURSDAY, Aug. 29, 2024 -- Climate change will increase people’s risk of salmonella poisoning from contaminated food, a new study warns.Increased humidity will make it more likely that leafy greens like lettuce will suffer from bacterial diseases, s.

Disease 242
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Number of fish species at risk of extinction fivefold higher than previous estimates, according to a new prediction

Science Daily: Pharmacology News

Researchers predict that 12.7% of marine teleost fish species are at risk of extinction, up fivefold from the International Union for Conservation of Nature's prior estimate of 2.5%. Their report includes nearly 5,000 species that did not receive an IUCN conservation status due to insufficient data.

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Why Breast Feeding May Be Even Healthier for Heavier New Moms

Drugs.com

THURSDAY, Aug. 29, 2024 -- Breastfeeding helps women shed those extra pounds of "pregnancy weight," a new study finds, and the effect is even more pronounced for moms who were overweight before their pregnancy. Among women who exclusively breastfed.

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New model to enhance extreme rainfall prediction

Science Daily: Pharmacology News

Scientists have developed new guidance and tools that could significantly improve the prediction of life-threatening flash flooding.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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BioMarin to lay off over 200 employees

BioPharma Drive: Drug Pricing

The company has reshuffled its executive team, cut back spending and trimmed its drug pipeline this year, changes aimed at refocusing its resources.

Drugs 148
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Seeing the future: Zebrafish regenerates fully functional photoreceptor cells and restores its vision

Science Daily: Pharmacology News

Blinding diseases lead to permanent vision loss by damaging photoreceptor cells, which humans cannot naturally regenerate. While researchers are working on new methods to replace or regenerate these cells, the crucial question is whether these regenerated photoreceptors can fully restore vision. By studying zebrafish, an animal naturally capable of photoreceptor regeneration, a team showed that regenerated photoreceptors are as good as original ones and regain their normal function, allowing the

Disease 284
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Pregnancy After 'Tubes Tied' Sterilization Is More Common Than Thought

Drugs.com

THURSDAY, Aug. 29, 2024 -- Women are becoming pregnant after having their tubes tied, even though the procedure is considered a “permanent” form of birth control, a new study warns.Between 3% and 5% of U.S. women who underwent tubal ligation later r.

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Ancient sea cow attacked by a crocodile and sharks sheds new light on prehistoric food chains

Science Daily: Pharmacology News

A new study showing how a prehistoric sea cow was preyed upon by not one, but two different carnivores -- a crocodilian and a shark -- is revealing clues into both the predation tactics of ancient creatures and the wider food chain millions of years ago.

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Weekend Catch-Up Sleep Could Do Your Heart Good

Drugs.com

THURSDAY, Aug. 29, 2024 -- Like to sleep in on the weekends?You’re probably doing your heart a world of good, a new study shows.Weekend “catch-up” sleep can lower a person’s risk of heart disease by up to 20%, according to findings to be presented T.

Disease 130