BioPharma Drive: Drug Pricing
AUGUST 29, 2024
Far fewer venture funding rounds were closed by cell and gene therapy developers over the first six months of 2024 than in prior years. Experts say there are several factors.
Drugs.com
AUGUST 29, 2024
THURSDAY, Aug. 29, 2024 (HeathDay News) -- The first known U.S. cluster of cases of bird flu in humans has been recorded at two poultry facilities in Colorado, the Centers for Disease Control and Prevention (CDC) reported Thursday.The nine infected.
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Science Daily: Pharmacology News
AUGUST 29, 2024
Chemists have developed a catalytic process that turns the largest component of today's plastic waste stream, polyolefin plastic bags and bottles, into gases -- propylene and isobutylene -- that are the building blocks of polypropylene and other types of plastics. The process uses inexpensive solid catalysts that can be scaled to industrial production, making this a potentially viable means of creating a circular economy for these throw-away plastics.
Drugs.com
AUGUST 29, 2024
THURSDAY, Aug. 29, 2024 -- A migraine drug can help stop the devastating headaches in their tracks, allowing sufferers to go about their daily lives with little to no symptoms, a new clinical trial has found.People who took ubrogepant (Ubrelvy).
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
AUGUST 29, 2024
The trial setbacks for Merck’s best-selling drug, which faces patent expiration in 2028, are a blow to the company’s plans for further indication expansion.
Science Daily: Pharmacology News
AUGUST 29, 2024
The public could have days or months of warning about a major earthquake through identification of prior low-level tectonic unrest over large areas, according to research by scientists who analyzed two major quakes in Alaska and California.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
AUGUST 29, 2024
Researchers predict that 12.7% of marine teleost fish species are at risk of extinction, up fivefold from the International Union for Conservation of Nature's prior estimate of 2.5%. Their report includes nearly 5,000 species that did not receive an IUCN conservation status due to insufficient data.
BioPharma Drive: Drug Pricing
AUGUST 29, 2024
Testimony from the heads of Express Scripts, Optum Rx and Caremark in July defending pharmacy benefit managers’ business practices could be coming back to bite them.
Science Daily: Pharmacology News
AUGUST 29, 2024
Astronomers have spotted a pair of galaxies in the act of merging 12.8 billion years ago. The characteristics of these galaxies indicate that the merger will form a monster galaxy, one of the brightest types of objects in the Universe.
Perficient: Drug Development
AUGUST 29, 2024
For most businesses, the holiday season is a critical time that often accounts for a significant portion of annual sales. To properly capitalize on this opportunity, companies must ensure their product information is accurate, consistent, and compelling across all channels. This is where Product Information Management (PIM) systems come into play.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
AUGUST 29, 2024
A new study sheds light on the vital role that the mixing of Atlantic and Arctic waters plays in sustaining the Atlantic Meridional Overturning Circulation (AMOC), which is crucial for regulating Earth's climate.
Drugs.com
AUGUST 29, 2024
THURSDAY, Aug. 29, 2024 -- Jillian Davis was pleased to be gifted a car seat during her pregnancy, from a family member who bought it online from a major retailer.But following the delivery of her daughter in late June, a car seat tech at her Salt.
Science Daily: Pharmacology News
AUGUST 29, 2024
Fungi can transform plant and animal products into delicious foods like cheese, miso and beer. A researcher argues that a type of filamentous mold -- Neurospora intermedia -- could also turn food waste into culinary treats. Currently, only Indonesians have discovered this secret; they grow the mold on leftover soy pulp from making tofu to create oncom.
Drugs.com
AUGUST 29, 2024
THURSDAY, Aug. 29, 2024 -- Smokers who quit the habit soon after being diagnosed with heart disease saw their odds for heart attack or death drop by almost half over the next five years, a new report found.However, those who simply cut back on.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
AUGUST 29, 2024
Researchers have developed a pioneering technique for producing large-scale graphene current collectors. This breakthrough promises to significantly enhance the safety and performance of lithium-ion batteries (LIBs), addressing a critical challenge in energy storage technology.
Drugs.com
AUGUST 29, 2024
THURSDAY, Aug. 29, 2024 -- Classroom cellphone bans should help improve learning environments in schools, a child development expert says.Keeping the devices out of classrooms would help focus attention, improve problem-solving and -- by allowing.
Science Daily: Pharmacology News
AUGUST 29, 2024
For decades, scientists have dreamt of a future where genetic diseases, such as the blood clotting disorder hemophilia, could be a thing of the past. Gene therapy, the idea of fixing faulty genes with healthy ones, has held immense promise. But a major hurdle has been finding a safe and efficient way to deliver those genes. Researchers have now made a significant breakthrough in gene editing technology that could revolutionize how we treat genetic diseases.
addgene Blog
AUGUST 29, 2024
If you’ve ever been looking for just the right CRISPR vectors on Addgene and found instead ones that were… pretty close, or at least close enough, you’ve found yourself with a common dilemma. Request the vectors you can find and use them as-is, saving time and effort but risking the potential of them not working, or spend a few weeks designing and cloning the vectors you actually want.
Drugs.com
AUGUST 29, 2024
THURSDAY, Aug. 29, 2024 -- Climate change will increase people’s risk of salmonella poisoning from contaminated food, a new study warns.Increased humidity will make it more likely that leafy greens like lettuce will suffer from bacterial diseases, s.
Science Daily: Pharmacology News
AUGUST 29, 2024
To understand the mysteries surrounding black holes, researchers at Tohoku University have created a simulation of accretion disk turbulence that possesses the highest-resolution currently available.
Drug Patent Watch
AUGUST 29, 2024
Ensuring that a generic drug meets FDA standards is crucial for maintaining the high quality and efficacy of medications. The FDA’s Office of Generic Drugs (OGD) plays a vital role in this process by following a rigorous review process to ensure that generic medications meet the same standards as their brand-name counterparts. The FDA’s review process for generic drugs involves several key steps.
Science Daily: Pharmacology News
AUGUST 29, 2024
Researchers have made a groundbreaking discovery about how sea stars (commonly known as starfish) manage to survive predatory attacks by shedding their own limbs. The team has identified a neurohormone responsible for triggering this remarkable feat of self-preservation.
Drug Target Review
AUGUST 29, 2024
What potential advantages does the CD5 modulation strategy offer over traditional CAR-T therapies? MR : Chimeric antigen receptor T-cell (CAR-T) therapy is very effective in treating patients with B-cell lymphoma, leukemia, and multiple myeloma, where we have six FDA-approved drugs. However, these treatments will eventually fail for the majority of patients, so there is a strong need for better CAR therapies.
Science Daily: Pharmacology News
AUGUST 29, 2024
A new study showing how a prehistoric sea cow was preyed upon by not one, but two different carnivores -- a crocodilian and a shark -- is revealing clues into both the predation tactics of ancient creatures and the wider food chain millions of years ago.
FDA Law Blog: Biosimilars
AUGUST 29, 2024
By Kurt R. Karst & Michael D. Shumsky — As readers of this blog know ( see, e.g. , here ), the Affordable Generics (and Biosimilars) Act has been floating around in Congress for the better part of two decades. That bill, addressing drug (and later biological product) patent settlement agreements (pejoratively referred to as “reverse payment agreements” by their opponents), was first introduced by Senator Herb Kohl (D-WI) in June 2006 as S. 3582 —well before the Biologics Price Competition an
Science Daily: Pharmacology News
AUGUST 29, 2024
Blinding diseases lead to permanent vision loss by damaging photoreceptor cells, which humans cannot naturally regenerate. While researchers are working on new methods to replace or regenerate these cells, the crucial question is whether these regenerated photoreceptors can fully restore vision. By studying zebrafish, an animal naturally capable of photoreceptor regeneration, a team showed that regenerated photoreceptors are as good as original ones and regain their normal function, allowing the
Drugs.com
AUGUST 29, 2024
THURSDAY, Aug. 29, 2024 -- Women are becoming pregnant after having their tubes tied, even though the procedure is considered a “permanent” form of birth control, a new study warns.Between 3% and 5% of U.S. women who underwent tubal ligation later r.
Science Daily: Pharmacology News
AUGUST 29, 2024
Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.
Drugs.com
AUGUST 29, 2024
THURSDAY, Aug. 29, 2024 -- Breastfeeding helps women shed those extra pounds of "pregnancy weight," a new study finds, and the effect is even more pronounced for moms who were overweight before their pregnancy. Among women who exclusively breastfed.
Science Daily: Pharmacology News
AUGUST 29, 2024
Scientists have developed new guidance and tools that could significantly improve the prediction of life-threatening flash flooding.
BioPharma Drive: Drug Pricing
AUGUST 29, 2024
The company has reshuffled its executive team, cut back spending and trimmed its drug pipeline this year, changes aimed at refocusing its resources.
Science Daily: Pharmacology News
AUGUST 29, 2024
A 'tag-team' between the oceans and continents millions of years ago devastated marine life and altered the course of evolution on Earth, according to a new study. Scientists say a string of severe environmental crises which happened between 185 and 85 million years ago triggered mass extinctions among ocean-living species.
Broad Institute
AUGUST 29, 2024
Denise By amatosni@broadinstitute.org August 29, 2024 Denise Denise Wellesley High School Wellesley, MA Mentors: Allison Uebele and Laura Drepanos Genetic Perturbation Platform In her BSSP application, Denise mentioned that last summer she attended a scientific talk at the Broad Institute given by Professor Zhang. She recalls, “He was talking about genetic editing.
Science Daily: Pharmacology News
AUGUST 29, 2024
Move over, Sonic. There's a new spin-jumping champion in town -- the globular springtail (Dicyrtomina minuta). This diminutive hexapod backflips into the air, spinning to over 60 times its body height in the blink of an eye, and a new study features the first in-depth look at its jumping prowess.
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