Thu.Sep 19, 2024

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Can the Fed’s rate cut change biotech’s ‘new normal’?

BioPharma Drive: Drug Pricing

Industry insiders hope the Fed’s decision to cut rates for the first time in years will boost biotech investment. But the long-awaited move won’t cure all that ails the sector, others cautioned.

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Breakthrough study predicts catastrophic river shifts that threaten millions worldwide

Science Daily: Pharmacology News

Researchers have uncovered key insights into the dangerous phenomenon of 'river avulsion,' offering a way to predict when and where rivers may suddenly and dramatically change course.

Research 125
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Some Diabetes Meds Could Lower Odds for Dementia, Parkinson's

Drugs.com

THURSDAY, Sept. 19, 2024 -- A specific class of diabetes drug appears to lower people’s risk for dementia and Parkinson’s disease, a new study shows.Sodium-glucose cotransporter-2 (SGLT2) inhibitors, also known as gliflozins, lower blood sugar by pr.

Disease 105
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Genetic tracing at the Huanan Seafood market further supports COVID animal origins

Science Daily: Pharmacology News

A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC). The data come from more than 800 samples collected in and around the Huanan Seafood Wholesale market beginning on January 1, 2020, and from viral genomes reported from early COVID-19 pa

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New Data Supports Animal Market Origins for COVID Pandemic

Drugs.com

THURSDAY, Sept. 19, 2024 -- The Hunan Seafood Wholesale wet market in Wuhan, China, has long been considered the most likely source of the coronavirus that caused the COVID-19 pandemic. That theory is now supported by a new study analyzing more.

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Over nearly half a billion years, Earth's global temperature has changed drastically, driven by carbon dioxide

Science Daily: Pharmacology News

A new study offers the most detailed glimpse yet into how Earth's surface temperature has changed over the past 485 million years. The data show that Earth has been and can be warmer than today -- but humans and animals cannot adapt fast enough to keep up with human-caused climate change.

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Scientists say we have enough evidence to agree global action on microplastics

Science Daily: Pharmacology News

An international group of researchers says two decades of research have generated sufficient knowledge about the sources and effects of microplastics to allow world leaders to agree measures to address them. The argument comes 20 years after the first ever study to coin the term microplastics to describe the microscopic fragments of plastics in our ocean.

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U.S. Health Care System Ranks Last Among Wealthy Nations, Report Finds

Drugs.com

THURSDAY, Sept. 19, 2024 -- Americans have the worst health care among the world’s wealthy nations, a new report says.People in the United States die the earliest and live the sickest lives out of 10 developed countries, even though the United S.

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Networks of Beliefs theory integrates internal and external dynamics

Science Daily: Pharmacology News

The beliefs we hold develop from a complex dance between our internal and external lives. A recent study uses well-known formalisms in statistical physics to model multiple aspects of belief-network dynamics. This multidimensional approach to modeling belief dynamics could offer new tools for tackling various real-world problems such as polarization or the spread of disinformation.

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'Exercise Is Medicine' for People With Parkinson's

Drugs.com

THURSDAY, Sept 19, 2024 -- Exercise, whether moderate- or high-intensity, can help ease Parkinson's symptoms, including fatigue, new research shows.As study lead author Dr. Philip Millar explained, Parkinson's patients are too often overwhelmed by.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Volcanoes may help reveal interior heat on Jupiter moon

Science Daily: Pharmacology News

By staring into the hellish landscape of Jupiter's moon Io -- the most volcanically active location in the solar system -- astronomers have been able to study a fundamental process in planetary formation and evolution: tidal heating.

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Some Chocolate Products Labeled 'Dairy-Free' Contain Milk, FDA Finds

Drugs.com

THURSDAY, Sept. 19, 2024 -- Consumers should be aware that some chocolate labeled as “dairy-free” actually contains milk, the U.S. Food and Drug Administration warns.This inaccurate labeling could put people with milk allergies in danger, the FDA no.

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Insights into South African population history from 10,000-year-old human DNA

Science Daily: Pharmacology News

Ancient DNA has provided spectacular insights into human history, particularly in Europe and Asia, where researchers have reconstructed the genomes of thousands of people. However, fewer than two dozen ancient genomes have been recovered from southern Africa -- specifically Botswana, South Africa and Zambia -- which has some of the world's earliest evidence of modern humans, with the oldest genomes dating back around 2,000 years.

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Roche’s Xofluza reduces flu transmission in Phase 3 study

BioPharma Drive: Drug Pricing

According to the company, the results are the first time an antiviral drug has reduced transmission of a respiratory virus in a global Phase 3 trial.

Virus 105
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Food fussiness a largely genetic trait from toddlerhood to adolescence

Science Daily: Pharmacology News

A new study compared survey results of parents with identical or non-identical twins in England and Wales from the ages of 16 months to 13 years. The study found that fussy eating is mainly influenced by genes and is a stable trait lasting from toddlerhood to early adolescence.

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How A Cell Anticipates the Seasons

Codon

This article by Niko McCarty is part of our Editor’s Column, a series of essays written by the Asimov Press team. Intelligence means perceiving information and then applying it to adapt to different contexts. That sounds an awful lot like what cells do. Consider the humble Escherichia coli , which uses its whip-like flagella to swim. In an article titled, “ The Baffling Intelligence of a Single Cell ,” writer and programmer James Somers describes how these microbes chase their

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Lake ice quality degrading as planet warms -- skaters, hockey players, ice truckers on thin ice

Science Daily: Pharmacology News

Ice may look safe for a game of pick-up hockey on the lake, but as a new study has found, looks can be deceiving. Warming winters are not only affecting ice thickness and timing -- when a lake freezes and thaws -- but also quality, making it potentially unstable and unsafe. The problem, say researchers, is that the unpredictable and warmer winter weather is creating thinner layers of black ice and sometimes a corresponding thicker layer of white ice, the unstable kind.

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Stroke Kills 7 Million Worldwide Each Year, and Deaths Are Rising

Drugs.com

THURSDAY, Sept. 19, 2024 -- Climate change and worsening diets are sending global rates of stroke and stroke deaths skyward, a new study warns.Almost 12 million people worldwide had a stroke in 2021, up 70% since 1990, according to a team led by.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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New research reenvisions Earth's mantle as a relatively uniform reservoir

Science Daily: Pharmacology News

Lavas from hotspots - -whether erupting in Hawaii, Samoa or Iceland -- likely originate from a worldwide, uniform reservoir in Earth's mantle, according to an evaluation of volcanic hotspots.

Research 101
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Breastfeeding Crucial to a Healthy Infant Microbiome, Lowering Asthma Risk

Drugs.com

THURSDAY, Sept. 19, 2024 -- Breastfeeding through the first year of infants' lives can lower their risk of asthma by colonizing their bodies with a healthy mix of microbes, a new study finds. Results show that breastfeeding beyond three months.

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Breastfeeding is crucial to shaping infant's microbes and promoting lung health

Science Daily: Pharmacology News

Human breast milk regulates a baby's mix of microbes, or microbiome, during the infant's first year of life. This in turn lowers the child's risk of developing asthma, a new study shows.

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Diabetes Med Metformin Could Cut Risks for Long COVID

Drugs.com

THURSDAY, Sept. 19, 2024 -- One of the most common diabetes drugs, metformin, might deliver an added bonus: Lowering users' odds for Long COVID.Long COVID can present with symptoms including chronic fatigue, brain fog and chest pain and it may last.

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The Complexity of Collaboration in Drug Discovery

Collaborative Drug

In a recent webinar, Janice Darlington from Collaborative Drug Discovery (CDD) with Tamsin Mansley from Optibrium discussed the importance of collaboration in drug discovery and showcased how their software platforms, CDD Vault and StarDrop , can enhance collaborative efforts.

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Do You Know the MIND Diet? It Might Keep You Sharp With Age

Drugs.com

THURSDAY, SEPT. 19, 2024 -- It's called the MIND diet and its primary aim is to help guard against thinking and memory declines as you age. But does it work?Yes, claims new research that found following the MIND diet for 10 years produced a small.

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Organic matter on Mars was formed from atmospheric formaldehyde

Science Daily: Pharmacology News

Researchers have developed a Martian atmospheric evolution model to propose a new theory about Mars's past.

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U.S. Wastewater Tests Show Bird Flu Virus Limited to Areas With Farm Animals

Drugs.com

THURSDAY, Sept. 19, 2024 -- An extensive look at wastewater samples taken across the United States from May to July found traces of the H5N1 bird flu popping up -- but only in areas populated by farm animals. The avian flu virus has been widespread.

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Breaking Barriers: New Developments in Oral Drug Delivery Systems

DrugBank

Oral drug delivery remains the gold standard in pharmaceutical administration. It offers convenience for patients, promotes medication adherence, and improves treatment outcomes. Compared to other routes, like injectables, oral drugs are cost-effective to manufacture and administer. However, translating a promising therapeutic candidate into a successful oral medication presents pharmacokinetic and pharmacodynamic challenges.

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How to Develop a Competitive Generic Drug Portfolio

Drug Patent Watch

The generic drug market in the United States is characterized by significant price volatility and shortages, driven by the structure of the market and the incentives for manufacturers. To address these issues, several market-based proposals have been put forth to optimize generic drug cost and availability.

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Dengue Cases Mount in Los Angeles

Drugs.com

THURSDAY, Sept. 19, 2024 -- The Los Angeles area is seeing a troubling increase in local dengue fever cases, health officials warned Wednesday. In a public notice posted on its website, the Los Angeles County Public Health Department said at least.

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Introducing.Addgene Quick Tips!

addgene Blog

If you’re looking for the best way to improve your lab techniques — but perhaps are a little limited on time — check out Addgene’s new Quick Tip series on YouTube!

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Genome Sequence of the Little Bush Moa Illuminates Avian Evolution

PLOS: DNA Science

Since discovering my first fossils in a stream behind the Baseball Hall of Fame in Cooperstown, New York, when I was 10, I’ve been fascinated with clues to past life. I was so excited to find what turned out to be worm borings that my mother trekked me up to a researcher at the American Museum of Natural History, who took the time to identify my specimens.

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Startup from George Church’s lab raises $75M to develop ‘supercell’ medicines

BioPharma Drive: Drug Pricing

GC Therapeutics claims it can create off-the-shelf therapies from induced pluripotent stem cells faster than by current methods with a simpler process.

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Perficient Wins 2024 Sitecore Practice Excellence Award

Perficient: Drug Development

Perficient is proud to announce that we have been recognized as Sitecore’s 2024 Practice Excellence Award Global Winner. This award recognizes Perficient for being a solution partner who is successful in building a business around their Sitecore practice, highlighting our power to adapt and grow. “We are honored to receive the Sitecore Practice Excellence Award, a testament to our unwavering commitment to innovation, growth and teamwork,” said Art Quinn, General Manager, DX Platform Solutions.

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