Drug Discovery World
FEBRUARY 5, 2024
Opening keynote Following a change to the schedule, Juliet Williams of Kymera Therapeutics launched the event with a popular keynote talk ‘Solving Big Problems with Small Molecule Degraders’. Williams discussed the advantages of the company’s ‘disease agnostic’ small molecule degraders, and its success so far in translating results from preclinical to clinical tests in dermatology, inflammation and oncology indications.
Science Daily: Pharmacology News
FEBRUARY 5, 2024
The Circumpolar Current works as a regulator of the planet's climate. Its origins were thought to have caused the formation of the permanent ice in Antarctica about 34 million years ago. Now, a study has cast doubt on this theory, and has changed the understanding of how the ice sheet in Antarctic developed in the past, and what this could mean in the future as the planet's climate changes.
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Drug Discovery World
FEBRUARY 5, 2024
For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode two, Where is the Ignite Theater tech leading us? At this year’s SLAS event, DDW has curated a track taking place in the Ignite Theater, sponsored by Integra Biosciences and Hamamatsu Corporation.
Science Daily: Pharmacology News
FEBRUARY 5, 2024
Scientists have found soundwaves from low-intensity focused ultrasound aimed at a place deep in the brain called the insula can reduce both the perception of pain and other effects of pain, such as heart rate changes.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
FEBRUARY 5, 2024
For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode two, Where is the Ignite Theater tech leading us? At this year’s SLAS event, DDW has curated a track taking place in the Ignite Theater, sponsored by Integra Biosciences and Hamamatsu Corporation.
Science Daily: Pharmacology News
FEBRUARY 5, 2024
Research involving has shown that a 'swarm' of more than 100 autonomous ground and aerial robots can be supervised by one person without subjecting the individual to an undue workload.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Chemical Biology and Drug Design
FEBRUARY 5, 2024
The synthesis, biological activity, and the structure–activity relationship of capsaicin and its derivatives are reviewed. Furthermore, we detailly describe the combination mechanism between capsaicin and TRPV1, TRPV1 related capsaicin derivatives as well. Abstract Capsaicin is the main active ingredient of chili peppers and the most pungent alkaloid.
Drug Discovery World
FEBRUARY 5, 2024
One-third (32%) of rare disease patients are not aware they can access unlicensed medicines through Early Access Programmes, new research has revealed. However, two-thirds (68%) of patients are comfortable receiving medicines before they’re licensed through their country’s healthcare system. The new data was released by pharma company Clinigen to mark the start of Rare Disease Month.
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- The weight-loss drug Zepbound provides more health benefits than dropping pounds and controlling diabetes, a new study shows.It also appears to help people with obesity manage their high blood pressure, results show.Patients.
Drug Discovery World
FEBRUARY 5, 2024
Hosted by DDW and sponsored by Astrea Biosciences “Cell and gene therapies – how can market growth be sustained to maximise on opportunities” – will be free to attend on 28 February at 7AM PST / 10AM EST / 3PM GMT / 4PM CET. Join this free webinar and learn about some of the key opportunities that are available to drug discovery and development companies following growth in the cell and gene therapy market.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
FEBRUARY 5, 2024
The pharma disclosed positive results from two studies testing its antibody drug nipocalimab in generalized myasthenia gravis or Sjögren's disease.
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- Rectal cancer often involves surgeries that can lead to a debilitating loss of bowel function for patients. However, new research suggests that a less aggressive approach to treating the disease has helped an increasing.
BioPharma Drive: Drug Pricing
FEBRUARY 5, 2024
In a related deal, Novo Holdings subsidiary Novo Nordisk will buy three major Catalent factories for $11 billion as it works to keep pace with demand for its obesity and diabetes medicines.
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- A U.S. Food and Drug Administration advisory panel on Friday addressed a continuing issue with pulse oximeters -- that they give less accurate readings for folks with darker skin.The devices are designed to measure oxygen.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Perficient: Drug Development
FEBRUARY 5, 2024
ERP | Enterprise Resource Planning Migration to the Cloud – July 2023 Go Live! Ryman Hospitality Properties, Inc. (NYSE: RHP) Business Challenge + Opportunity Migrate existing footprint and well-established business processes from Oracle EBS and NetSuite financials into Oracle ERP Cloud (Fusion), with over 500 custom reports written across different tool sets (FSGs, Discoverer, GL Wand, and other BI type or reports) Achievements: Sunset/Archive Oracle EBS and GL Wand Migrated Receivables and Col
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- Americans pay nearly three times as much for their prescription drugs as residents of other nations do, new research shows.Drug prices in the United States average nearly 2.8 times those seen in 33 other countries, the.
Science Daily: Pharmacology News
FEBRUARY 5, 2024
For more than 50 years, the National Hurricane Center has used the Saffir-Simpson Windscale to communicate the risk of property damage; it labels a hurricane on a scale from Category 1 (wind speeds between 74 -- 95 mph) to Category 5 (wind speeds of 158 mph or greater). But as increasing ocean temperatures contribute to ever more intense and destructive hurricanes, climate scientists wondered whether the open-ended Category 5 is sufficient to communicate the risk of hurricane damage in a warming
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- New research suggests healthy lifestyles can help stave off dementia, perhaps by building a resilient 'cognitive reserve' in the aging brain. The study was based on the brain autopsies on 586 people who lived to an average.
Science Daily: Pharmacology News
FEBRUARY 5, 2024
Many Indigenous peoples and local communities around the world are leading very satisfying lives despite having very little money. This research shows that many societies with very low monetary income have remarkably high levels of life satisfaction, comparable to those in wealthy countries.
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- Even mild cases of COVID can trigger insomnia in most people, a new study reports.About three out of four people with mild COVID (76%) reported experiencing insomnia following their illness.Further, nearly one in four (23%).
SCIENMAG: Medicine & Health
FEBRUARY 5, 2024
Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- Follow-up from recent surgery for an enlarged prostate has revealed that Britain's King Charles III has cancer, Buckingham Palace announced Monday.The palace did not disclose the type of cancer that was discovered."During.
SCIENMAG: Medicine & Health
FEBRUARY 5, 2024
UNIVERSITY PARK, Pa. — The bacteria and microorganisms that live within the human body — the microbiota — can impact human health, disease risk and even how the body absorbs medications, but the details of these processes are unclear.
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- If you're over 65, you likely struggle sometimes to hear conversations clearly, but ignoring that may prompt even more serious health problems, experts say. If left unchecked, hearing loss can lead to social isolation and.
SCIENMAG: Medicine & Health
FEBRUARY 5, 2024
Alterations in the chemical modifications that control gene expression, known as Epigenetics, have proven to be one of the most characteristic properties of all human tumors. This realization has generated the development of very intense pharmacological research to find drugs that act at this level against cancer.
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- Police killings of unarmed Black people are robbing the Black community of a precious commodity – sleep. Black adults across the United States suffer from sleep problems after they’re exposed to news of killings.
SCIENMAG: Medicine & Health
FEBRUARY 5, 2024
How can inclusivity be achieved in cardiopulmonary exercise tests for individuals facing lower limb injuries or disabilities that make it impossible to pedal a bicycle?
Drugs.com
FEBRUARY 5, 2024
MONDAY, Jan. 5, 2024 -- Accessing mental health care via telehealth boomed during the pandemic, and it continues to be a valuable resource for patients. However, it could still be tough to find, depending on the clinics available in your area, new.
NIOSH Science Blog: Drugs
FEBRUARY 5, 2024
Nearly 1 in 5 of all workplace fatalities occur in the construction industry (BLS, 2024). In 2022 there were 1,092 fatalities in the construction industry (BLS, 2024); in 2021 and 2022 there were 144,480 cases of construction industry workers missing days away from work from a non-fatal injury or illness (BLS, 2023). These and other statistics show that construction remains one of the most dangerous industries for workers.
Drugs.com
FEBRUARY 5, 2024
MONDAY, Feb. 5, 2024 -- Unprovoked shark attacks increased slightly worldwide last year, but twice as many people died from shark bites as the year before, new data show.There were 69 unprovoked shark attacks in 2023, higher than the five-year.
SCIENMAG: Medicine & Health
FEBRUARY 5, 2024
Tokyo, Japan – A recent randomized controlled trial in Tokyo, Japan, has unveiled the positive impact of early mobilization, assisted by mobile patient lifts, on the recovery of ventilated intensive care unit (ICU) patients. The debate surrounding the efficacy of early mobilization in ICU has persisted for an extended period. Credit: Dr.
Science Daily: Pharmacology News
FEBRUARY 5, 2024
A new species of pterosaur from specimens found on the Isle of Skye, Scotland, has been announced.
SCIENMAG: Medicine & Health
FEBRUARY 5, 2024
Petrina Kamya, PhD, Head of AI Platforms and President of Insilico Medicine Canada, will present at the BIO CEO & Investor Conference happening Feb. 26-27 at the New York Marriott Marquis in New York City. Dr. Kamya will speak as part of the panel “AI within Biopharma: Separating Value from Hype,” on Feb.
Science Daily: Pharmacology News
FEBRUARY 5, 2024
The workings of the ultrasonic warning sounds produced by the wings of a species of moth have been revealed.
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