Drug Discovery World

SEPTEMBER 5, 2023

It’s not unusual for such a dynamic industry to have regular shake-ups in senior leadership, especially as innovative new technologies create brand new roles. The last couple of months have seen a number of high-profile job moves in drug discovery. Dr Robert Kirby, COO and Dr Edward Stevens, CSO Metrion Biosciences Kirby has been promoted from his role as Director of Operations, where he oversaw Metrion’s recent site move and doubling of staff headcount.

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BioPharma Drive: Drug Pricing

SEPTEMBER 5, 2023

The FDA-approved therapy, called Palforzia, was little used, leading Nestle to abandon a business it had secured in a $2.6 billion deal three years ago.

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Drug Discovery World

SEPTEMBER 5, 2023

BenevolentAI has dosed the first patients in Phase I first-in-human studies of its oral phosphodiesterase 10 (PDE10) inhibitor, BEN-8744, intended for the treatment of ulcerative colitis (UC). The topline data readout from this study is expected in the first quarter of 2024. UC is a chronic disease that causes inflammation and ulceration of the inner lining of the colon and rectum.

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Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 -- Even before Roe v. Wade was overturned in 2022, many U.S. women lived far from a clinic where they could get abortion pills. Now, a new study suggests that telemedicine can help fill that gap. The study focused on one.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Drug Discovery World

SEPTEMBER 5, 2023

In the eleventh eBook of the Hamilton series ‘Analytical Methods for Viral Vector Development and Manufacturing in Gene Therapy’, we learn about: Gene therapy: history, viral vectors and the role of CDMOs Automation of analytical assays during viral vector development and manufacturing The solutions that Hamilton offers to customers working in this field, both in research and GMP-regulated environments The post Analytical methods for viral vector development and manufacturing in gene

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Drug Patent Watch

SEPTEMBER 5, 2023

Pharmacists play a crucial role in drug repurposing due to the vast amount of opportunities that exist in this innovative approach. Drug development and registration can be costly, time-consuming, and… The post Pharmacists Can Play Key Role in Drug Repurposing appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 – When new COVID variant BA.2.86 emerged in late July, scientists had concerns about its ability to evade immunity. But early lab tests seem to be easing those fears, as well as concerns over the variant's ability to spread.

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Drug Discovery World

SEPTEMBER 5, 2023

Label-free interaction analysis takes discovery to a new level. It removes inaccuracies and inefficiencies, but it also uncovers a new layer of insight into the kinetic activity and binding specificity of a greater range of analytes. GCI technology brings you closer to your analytes, allowing you to see interactions in their truest form. The post Binding kinetics in hours instead of days with label-free interaction analysis appeared first on Drug Discovery World (DDW).

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BioPharma Drive: Drug Pricing

SEPTEMBER 5, 2023

The announcement marks progress for Beam after trial delays, and is the first time in the U.S. that a patient has received a base editing treatment.

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Drug Discovery World

SEPTEMBER 5, 2023

A new eBook is now available from Malvern Panalytical: ‘ Faster, more accurate and deeper insight: How to make the switch to label-free interaction analysis.’ Label-free interaction analysis takes discovery to a new level. It removes inaccuracies and inefficiencies, but it also uncovers a new layer of insight into the kinetic activity and binding specificity of a greater range of analytes.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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BioPharma Drive: Drug Pricing

SEPTEMBER 5, 2023

The signals of a return to growth are emerging. As commercial leaders gear up for 2024 planning, they must prepare to fight for resources in a budget constrained environment.

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Drug Discovery World

SEPTEMBER 5, 2023

The UK’s National Institute for Health and Care Excellence (NICE) has recommended Elfabrio (pegunigalsidase alfa) as an option for treating Fabry disease (or alpha-galactosidase deficiency). The drug is recommended for use on the NHS under the terms of a confidential commercial agreement. Pegunigalsidase alfa is a novel enzyme replacement therapy (ERT) administered via intravenous infusion every two weeks and delivers a modified version of the enzyme α-galactosidase A.

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Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 -- In recent years, the opioid epidemic has been worsened by the advent of street fentanyl, an illicit version of a powerful prescription painkiller. But experts now warn that the threat posed by fentanyl may ultimately pale.

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Drug Target Review

SEPTEMBER 5, 2023

A recently published study in Nature Communications led by Dr Ashley Harms and her team at the University of Alabama at Birmingham explores further. By employing a mouse model of Parkinson’s disease, the researchers have illuminated a surprising revelation: it’s the border-associated macrophages (BAMs), not the microglia, that steer the neuroinflammatory response within the brain.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 -- You might think you know what a normal body temperature is, but there is no such thing. Analyzing the age-old belief that 98.6 Fahrenheit is normal human temperature, scientists at Stanford Medicine found that your.

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SCIENMAG: Medicine & Health

SEPTEMBER 5, 2023

Two scientists at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have received prestigious ERC Starting Grants from the European Commission: Clarissa Campbell and Barbara Maier. In Clarissa Campbell’s laboratory, researchers are working to better understand the interplay between the immune system and metabolism.

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addgene Blog

SEPTEMBER 5, 2023

We excited to announce the fourth edition of our popular eBook, Plasmids 101, is now available!

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SCIENMAG: Medicine & Health

SEPTEMBER 5, 2023

Organometallic compounds, molecules made up of metal atoms and organic molecules, are often used to accelerate chemical reactions and have played a significant role in advancing the field of chemistry. Credit: Takebayashi et al.

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Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 -- Suicides by Americans aged 10 to 24 are continuing to climb and guns are increasingly the method of choice in these tragedies, a new report finds. Easy access to firearms can mean suicide is often impulsively done and.

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SCIENMAG: Medicine & Health

SEPTEMBER 5, 2023

CHAMPAIGN, Ill. — Seven years after an initial $17.9 million award from the National Institutes of Health, the Illinois Kids Development Study at the University of Illinois Urbana-Champaign will receive approximately $13.7 million – awarded in two phases – to continue its work for another seven years.

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Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 -- Smoking may not only harm the smoker and those who breathe in the secondhand fumes, but also their future children. New research suggests that boys who smoke in their early teens risk passing on harmful genetic traits to.

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Science Daily: Pharmacology News

SEPTEMBER 5, 2023

Researchers report that the flexible shoulders and elbows that allow us to throw a football or reach a high shelf may have evolved as a natural braking system that let our primate ancestors get out of trees without dying. The researchers used sports-analysis software to compare the climbing movements of chimpanzees and small monkeys called mangabeys.

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Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 -- Just 1 in 4 children with autism is diagnosed before age 3, but a new eye-tracking technology may allow for earlier diagnosis and intervention, according to three clinical studies of more than 1,500 kids. Autism is a.

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BioPharma Drive: Drug Pricing

SEPTEMBER 5, 2023

The biotech, one of several advancing RNA editing medicines, expects to obtain “proof-of-mechanism” data in patients with the inherited disorder alpha-1 antitrypsin deficiency by next year.

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Science Daily: Pharmacology News

SEPTEMBER 5, 2023

The immense bubble is 820 million light years from Earth and believed to be a fossil-like remnant of the birth of the universe.

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Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 -- It’s important for men to be familiar with the warning signs of prostate cancer and get screened because it’s the second-leading cause of cancer death in men, an expert says. While there will be more than 288,000.

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BioPharma Drive: Drug Pricing

SEPTEMBER 5, 2023

The hub-and-spoke biotech has raised more than $190 million in total to fund drug development for rare autoimmune and blood conditions.

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Science Daily: Pharmacology News

SEPTEMBER 5, 2023

Right at the bottom of the deep sea, the first very simple forms of life on earth probably emerged a long time ago. Today, the deep sea is known for its bizarre fauna. Intensive research is being conducted into how the number of species living on the sea floor have changed in the meantime. Some theories say that the ecosystems of the deep sea have emerged again and again after multiple mass extinctions and oceanic upheavals.

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Drug Patent Watch

SEPTEMBER 5, 2023

Annual Drug Patent Expirations for PHEXXI Phexxi is a drug marketed by Evofem Inc and is included in one NDA. It is available from one supplier. There are four patents… The post New patent expiration for Evofem Inc drug PHEXXI appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs.com

SEPTEMBER 5, 2023

TUESDAY, Sept. 5, 2023 -- The two "freezing" episodes that Sen. Mitch McConnell experienced recently weren't strokes or seizures, the Capitol physician said in a new letter released Tuesday.

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Drug Patent Watch

SEPTEMBER 5, 2023

Annual Drug Patent Expirations for WYNZORA Wynzora is a drug marketed by MC2 and is included in one NDA. It is available from one supplier. There are two patents protecting… The post New patent for MC2 drug WYNZORA appeared first on DrugPatentWatch - Make Better Decisions.

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SCIENMAG: Medicine & Health

SEPTEMBER 5, 2023

WASHINGTON (Sept. 5, 2023)–Nursing homes that unionize are more likely to report workplace injury and illness data to the Occupational Safety and Health Administration, a new study published today in the journal Health Affairs says. Credit: The George Washington University WASHINGTON (Sept.

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Fierce BioTech

SEPTEMBER 5, 2023

Winter is Coming: How to Engage Doctors Under Pressure pesurya Tue, 09/05/2023 - 23:32 Tue, 10/24/2023 - 11:00 Resource Type Webinar Maxim Polyakov Tim Russell Duration 60 Minutes Join our expert panel in a discussion of the latest trends in doctor communication preferences. Based on a recent M3 survey of doctors across the EU5 markets, our experts will they share their key insights, lead an interactive discussion, and answer the audience's questions to explore how best to engage with doctors as

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SCIENMAG: Medicine & Health

SEPTEMBER 5, 2023

LOS ANGELES — Keck Medicine of USC has named Chris Allen chief financial officer (CFO), effective Aug. 31. He previously served as interim CFO of Keck Medicine and CFO of Keck Medical Center of USC. Credit: Ricardo Carrasco III LOS ANGELES — Keck Medicine of USC has named Chris Allen chief financial officer (CFO), effective Aug.

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