Science Daily: Pharmacology News
APRIL 3, 2025
In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning point in the antibiotics crisis.
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- Health experts are warning that whooping cough, also known as pertussis, is making a dangerous comeback. Cases are rising across the country, and Louisiana recently reported that two infants have died -- the state’s.
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Science Daily: Pharmacology News
APRIL 3, 2025
A switch of just two weeks from a traditional African diet to a Western diet causes inflammation, reduces the immune response to pathogens, and activates processes associated with lifestyle diseases. Conversely, an African diet rich in vegetables, fiber, and fermented foods has positive effects. This study highlights the significant impact of diet on the immune system and metabolism.
BioPharma Drive: Drug Pricing
APRIL 3, 2025
The Swiss drugmaker, which holds European rights to Elevidys, suspended three trials while researchers investigate the death of a young man who died following treatment.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
APRIL 3, 2025
Researchers have developed a method that shows how the nervous system and sensory organs are formed in an embryo. By labeling stem cells with a genetic 'barcode', they have been able to follow the cells' developmental journey and discover how the inner ear is formed in mice. The discovery could provide important insights for future treatment of hearing loss.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
APRIL 3, 2025
Scientists have helped to construct a detailed timeline for bacterial evolution, suggesting some bacteria used oxygen long before evolving the ability to produce it through photosynthesis.
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- An experimental blood test might be able to help doctors predict whether someone will recover their mobility following a spinal cord injury.The test looks for fragments of spinal cord DNA floating freely in a persons b.
Science Daily: Pharmacology News
APRIL 3, 2025
A solar wind event from 2017 that hit Jupiter and compressed its magnetosphere created a hot region spanning half Jupiter's circumference.
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- Death comes for everyone, be they rich or poor.But no amount of money will help Americans live longer than Europeans, a new study says.Even the richest Americans face shorter lifespans compared to well-heeled Europeans.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
APRIL 3, 2025
How does a robotic arm or a prosthetic hand learn a complex task like grasping and rotating a ball? Researchers address the classic 'nature versus nurture' question. The research demonstrates that the sequence of learning, also known as the 'curriculum,' is critical for learning to occur. In fact, the researchers note that if the curriculum takes place in a particular sequence, a simulated robotic hand can learn to manipulate with incomplete or even absent tactile sensation.
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- A group of 23 states and Washington, D.C., is suing the U.S. Department of Health and Human Services (HHS) over a sudden cut of $12 billion in public health funding. The lawsuit says the rollback will disrupt vital.
Science Daily: Pharmacology News
APRIL 3, 2025
Engineers have created new technology that can move cells without touching them, enabling critical tasks that currently require large pieces of lab equipment to be carried out on a benchtop device.
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- The longtime leader of a federal health program for 9/11 survivors and first responders has been fired, worrying many advocates and lawmakers. The program serves more than 100,000 people. Dr. John Howard, head of the.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
APRIL 3, 2025
The delayed decision comes amid a major organizational shakeup that included the departure of top vaccine official Peter Marks.
Science Daily: Pharmacology News
APRIL 3, 2025
The same dirt that clings to astronauts' boots may one day keep their lights on. Researchers created solar cells made out of simulated Moon dust. The cells convert sunlight into energy efficiently, withstand radiation damage, and mitigate the need for transporting heavy materials into space, offering a potential solution to one of space exploration's biggest challenges: reliable energy sources.
BioPharma Drive: Drug Pricing
APRIL 3, 2025
More than three-quarters of private biotech investment tracked by BioPharma Dive between January and March was distributed via rounds worth at least $100 million, which experts believe reflects a strategic shift.
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- Strokes caused by an artery tear are landing five times as many Americans in the hospital these days, a new study says.Cervical artery dissection involves a small tear in the inner lining of an artery in the neck that.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Broad Institute
APRIL 3, 2025
MPG Primer: Fine-mapping Complex Traits in Biobanks By Rose Circeo April 3, 2025 Breadcrumb Home MPG Primer: Fine-mapping Complex Traits in Biobanks The Primer on Medical and Population Genetics is a series of weekly lectures on genetics topics related to human populations and disease. Experts from across the Medical and Population Genetics community at the Broad Institute give in-depth introductions to research in human genetics through overviews of core concepts and practical tutorials on tool
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- Life is busy, and some folks simply dont have time until the weekend to work out.Turns out, thats just fine for their health, a new study suggests.Weekend warriors who cram their weeks exercise into one or two days ap.
DrugBank
APRIL 3, 2025
Here at DrugBank, we understand the critical importance of addressing drug safety and toxicity early in development. Developing a new therapeutic is a complex and high-stakes process, often spanning over a decade and requiring investments that exceed billions of dollars. Despite this significant commitment of time and resources, many drug candidates fail in clinical trials, with safety and toxicity concerns being one of the leading causes.
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- Cant get your teenage girl off her smartphone, iPad or laptop?This could cost her much-needed sleep and increase her risk of depression, a new Swedish study says.Teenagers who spend more time on screens tend to get worse s.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
APRIL 3, 2025
Drastic declines in biodiversity due to human activities present risks to understanding animal behaviors such as tool use, according to new research. Shrinking animal populations make the study of these behaviors increasingly difficult, underscoring the urgency of targeted conservation efforts and inclusive conservation strategies. Action is needed not only for research, but also to respect our shared cultural heritage with animal species.
Drugs.com
APRIL 3, 2025
THURSDAY, April 3, 2025 -- U.S. Sen. Cory Booker stood on the Senate floor and spoke for 25 hours and 5 minutes this week, breaking the modern record for the longest Senate speech ever. Senate rules allow a member who is recognized by the presiding.
Broad Institute
APRIL 3, 2025
Scientists have developed a way to scale up spatial genomics and lower costs By Allessandra DiCorato April 3, 2025 Breadcrumb Home Scientists have developed a way to scale up spatial genomics and lower costs A new computational approach eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue. By Allessandra DiCorato April 3, 2025 Credit: Chenlei Hu, Chen lab Spatial map of cell types in a mouse embryo.
Chemical Biology and Drug Design
APRIL 3, 2025
The development of the first reported chemical probes selective for SRPK3. 1-(4-cyanophenyl)-3-phenylurea was identified as an initial hit for SRPK3 through a kinase screen and further optimized to produce the top compound BP152 that has an SRPK3 IC 50 of 2.1M, high selectivity over SRPK1 and SRPK2, and invitro anti-cancer activity. ABSTRACT The serine arginine protein kinases (SRPKs) are a family of kinases whose irregular function is implicated in cancer and viral infections.
PLOS: DNA Science
APRIL 3, 2025
Hitler’s “final solution” attempted to strip the German population of Jewish people and others deemed not white. At the same time, the Lebensborn program sought to purify the Aryan gene pool and counter a plunging birthrate through “homes” where “hereditarily healthy” Aryan women conceived, carried, and bore the “racially valuable” children of SS men.
Chemical Biology and Drug Design
APRIL 3, 2025
Tanshinone IIA curbed inflammatory response, myocardiocyte apoptosis, oxidative stress, and ferroptosis under myocardial ischemiareperfusion injury context via activating HDAC1-repressed Nrf2-xCT/Gpx4/HO-1 axis. ABSTRACT Myocardial ischemia/reperfusion injury (MIRI) brings secondary injury to heart tissues and involves complicated pathophysiological activities, such as cell death, oxidative stress, and inflammation.
BioPharma Drive: Drug Pricing
APRIL 3, 2025
Mehmet Oz, a physician and TV personality, takes office as HHS lays off thousands of staffers and Republicans float potential cuts to Medicaid.
FDA Law Blog: Biosimilars
APRIL 3, 2025
By John W.M. Claud & JP Ellison Last June, the United States Supreme Court issued four landmark decisions that curbed executive agency powers. Those decisions are changing the way agencies, including FDA, exercise their rulemaking and enforcement authorities. Regardless your position on the correctness of the holdings or the reasoning behind them, Loper Bright , Jarkesy , EPA v.
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