Mon.Sep 30, 2024

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£3m boost to paediatric brain cancer research

Drug Discovery World

Experts from Cancer Research UK Children’s Brain Tumour Centre of Excellence in Cambridge, UK are set to share around £3.2 ($4.2) million to find and test better and less toxic ways to treat children’s brain tumours. The funding announcement comes during Childhood Cancer Awareness Month. Brain tumours are the leading cause of cancer death in children and those that do survive often face life-changing side effects as a result of their treatment.

Research 235
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Frequent fizzy or fruit drinks and high coffee consumption linked to higher stroke risk

Science Daily: Pharmacology News

Frequent drinking of fizzy drinks or fruit juice is associated with an increased risk of stroke, according to new findings. The research also found that drinking more than four cups of coffee per day also increases the risk of stroke.

Research 121
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Introducing DDW Research & Consultancy services

Drug Discovery World

Over the past 20 years, DDW has established itself as an authoritative, credible and industry leading business information platform. It makes sense then, with a close eye on industry trends and developments along with global perspective, that DDW expands its offering to include Research & Consultancy services. Through a range of surveys, in-depth interviews, primary and secondary research, round tables, events and focus groups, our consultants can provide competitive market intelligence, ind

Research 147
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Roche turns to a startup in search for new breast cancer drugs

BioPharma Drive: Drug Pricing

The Swiss pharma is paying Regor Therapeutics $850 million to buy a pair of prospects it sees as potential successors to blockbuster medicines from Pfizer and Eli Lilly.

Drugs 114
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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What to expect from Drug Discovery 2024

Drug Discovery World

Diana Spencer reveals what will be on offer at Drug Discovery 2024, including DDW’s new research and consultancy service. With a theme of ‘connecting minds, transforming science, empowering the community’, Drug Discovery 2024 will take place 2-3 October 2024 at the Excel in London, UK. This year, the event will cover therapeutic themes including mechanisms of ageing and cell & gene therapy, along with advances in assay design, applications in high content imaging, target identification

Drugs 147
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Falling Linked to Raised Risk of Dementia in Older People

Drugs.com

MONDAY, Sept. 30, 2024 -- More than 14 million seniors a year take a tumble, and those falls can be life-changing. "The relationship between falls and dementia appears to be a two-way street," said Molly Jarman, senior author of a new study showing.

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Could a bout of COVID protect you from a severe case of flu?

Science Daily: Pharmacology News

New findings on how past viral respiratory infections affect future, unrelated ones could lead to therapies for boosting general antiviral immunity -- and potentially pandemic preparedness.

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DDW Highlights: 30 September 2024

Drug Discovery World

The latest episode of the DDW Highlights podcast is now available to listen to and watch below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The publication of DDW’s latest eBook on immunotherapy has coincided with some interesting developments in this therapy area, particularly monoclonal antibodies, including two new regulatory approvals.

Therapies 130
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Cluster of 8 Possible Human Bird Flu Cases Now Reported in Missouri

Drugs.com

MONDAY, Sept. 30, 2024 -- In what could be the first cases of bird flu spreading between humans in the United States, a group of potential H5N1 infections in Missouri has now grown to eight.Antibody tests to confirm any H5N1 infection are still.

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Listicle: Introducing DDW Research & Consultancy services

Drug Discovery World

Over the past 20 years, DDW has established itself as an authoritative, credible and industry leading business information platform. It makes sense then, with a close eye on industry trends and developments along with global perspective, that DDW expands its offering to include Research & Consultancy services. Through a range of surveys, in-depth interviews, primary and secondary research, round tables, events and focus groups, our consultants can provide competitive market intelligence, ind

Research 130
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Medical Coding in Clinical Data Management

Quanticate

In any clinical trial conduct, recording and storing data in a controlled, consistent, and reproducible manner for data retrieval and analysis is a necessity for regulatory compliance and clinical study success.

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Immunotherapy companies OncoC4 and AcroImmune to merge

Drug Discovery World

Biopharmaceutical companies OncoC4 and AcroImmune, both co-founded by CEO, Yang Liu and CMO, Pan Zheng, have entered into a definitive merger agreement. Under the terms of the agreement, OncoC4 will acquire 100% of the outstanding equity interests of AcroImmune. The merger expands OncoC4’s wholly owned immunotherapy pipeline with the addition of AI-081, a PD-1/VEGF bispecific antibody with best-in-class potential.

Therapies 130
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America's Pediatricians Want You to Read a Book With Your Child

Drugs.com

MONDAY, Sept. 30, 2024 -- Read to your little ones.That's the American Academy of Pediatrics' (AAP) prescription for fostering loving, nurturing relationships during early infancy and early childhood -- a time of critical brain development."Reading.

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First biologic drug for COPD gets green light in US and China

Drug Discovery World

Dupixent (dupilumab) has become the first biologic medicine for chronic obstructive pulmonary disease (COPD) in the US and China. Sanofi and Regeneron secured approvals from both the US Food and Drug Administration (FDA) and China’s National Medical Products Administration (NMPA) in the same week. It is approved for adults with uncontrolled chronic obstructive pulmonary disease (COPD) characterised by raised blood eosinophils.

Disease 130
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Despite Progress, America's Fight Against Toxic Lead Far From Over

Drugs.com

MONDAY, Sept. 30, 2024 -- Toxic lead continues to pose a danger to U.S. consumers despite years of progress to reduce exposure, claims a study spanning four states."Consumer products were consistently identified as one of the main sources of lead.

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Webinar: Learn about the challenges for cell and gene therapies

Drug Discovery World

In this webinar on 8 October 3-4PM BST , hosted by DDW and sponsored by Benchling, you will learn about the challenges and advancements driving drug development for cell and gene therapies. You will hear from Erik Wiklund, CEO of Circio, Ali Pashazadeh, CEO of Treehill Partners, and Gerard Caelles, CBO at Splice Bio. Erik Wiklund will discuss how circular RNA is crucial to the development of next-generation cell and gene therapy products.

Therapies 130
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1 in 3 Teens Have Trouble Obtaining Menstrual Tampons or Pads

Drugs.com

MONDAY, Sept. 30, 2024 -- One in every three girls may not have access to menstrual products, something researchers are dubbing "period poverty."“Our study highlights the widespread nature of period poverty and the need for broad actions -- both l.

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High-performance microplates for discovery sciences with vertical supply chain ownership

Drug Discovery World

This advertorial appeared in DDW Volume 25 – Issue 4, Fall 2024 Read the digital issue Since 1996, Aurora Microplates has been at the forefront of microplate technology and innovation. Aurora Microplates pioneered the use of high-performance materials (Cyclic Olefin Polymer) and precise molding production methods to make the chemically purest, flattest plates available, keeping our products ready for demanding science applications.

Science 130
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What Do Families Fight About Most? New Study Finds Out

Drugs.com

MONDAY, Sept. 30, 2024 -- In a world where families may be more apt to interact with technology than with one another, some things never change.Many still struggle to get along. But just what do 21st century families fight about?A new survey of.

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Last chance to register: Driving neuroscience drug discovery research

Drug Discovery World

In this webinar on 30 September, from 3-4PM BST, hosted by DDW and sponsored by ApconiX, you will hear from Dr Isaac Klein, Chief Scientific Officer at Dewpoint Therapeutics, Dr Sam Clark, CEO of Terran Biosciences, and Professor Ruth Roberts, Co-founder and Director of Safety Science at ApconiX. Dr Klein shares how Dewpoint applies insights into the subcellular organisation of biochemical processes into membrane-less compartments to discover novel drug targets and revolutionary drugs for diseas

Research 130
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The Impact of Patent Expirations on Generic Drug Markets

Drug Patent Watch

Patent expirations have a significant impact on the pharmaceutical industry, particularly on the generic drug market. When a drug’s patent expires, other manufacturers can produce and market generic versions of the drug, leading to increased competition and lower prices.

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A river is pushing up Mount Everest's peak

Science Daily: Pharmacology News

Mount Everest is about 15 to 50 meters taller than it would otherwise be because of uplift caused by a nearby eroding river gorge, and continues to grow because of it.

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Black Babies With Heart Abnormalities Face Higher Death Risk

Drugs.com

MONDAY, Sept. 30, 2024 -- Black American infants born with congenital heart disease are less likely to survive to the age of 1, compared to white babies with the condition, a new study finds.The research suggests that Black infants aren't reaping.

Disease 89
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New synthesis strategy could speed up PFAS decontamination

Science Daily: Pharmacology News

Engineers have developed an innovative way to make covalent organic frameworks, special materials that can be used to trap gases, filter water and speed up chemical reactions.

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Synthetic THC May Calm Agitation in Alzheimer's Patients

Drugs.com

MONDAY, Sept. 30, 2024 -- A synthetic form of the active ingredient in cannabis helps reduce agitation in people with Alzheimer's, new research shows.Synthetic THC (dronabinol) also gave patients' caregivers a boost, according to findings presented.

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Watch water form out of thin air

Science Daily: Pharmacology News

Palladium, a rare metallic element, can rapidly generate water from hydrogen and oxygen. Researchers witnessed this process at the nanoscale for the first time with an electron microscope. By viewing the process with extreme precision, researchers discovered how to optimize it to generate water at a faster rate. Process could be used to generate water on-demand in arid environments, including on other planets.

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Q&A: How Terra became a backbone of public health pathogen surveillance

Broad Institute

Q&A: How Terra became a backbone of public health pathogen surveillance By Allessandra DiCorato September 30, 2024 Breadcrumb Home Q&A: How Terra became a backbone of public health pathogen surveillance Bronwyn MacInnis and Daniel Park reflect on how Terra, a scalable and secure open-source platform for biomedical data management and analysis, is making genomics accessible to public health labs.

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Tongan volcanic eruption triggered by explosion as big as 'five underground nuclear bombs'

Science Daily: Pharmacology News

The Hunga Tonga underwater volcano was one of the largest volcanic eruptions in history, and now, two years later, new research has revealed its main trigger.

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Aktis raises $175M to fuel radiopharma drug development

BioPharma Drive: Drug Pricing

Among the investors in Aktis’ Series B round were Bristol Myers Squibb, Eli Lilly and Merck & Co., all of which have expanded their involvement in the radiopharma field.

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The Vikings were part of a global network trading in ivory from Greenland

Science Daily: Pharmacology News

New research shows that the Vikings traveled more than 6,000 kilometers to the Arctic to hunt for walrus. DNA analyses reveal that walrus ivory from Greenland was brought to Europe and probably as far as the Middle East [M1] via extensive trade networks.

DNA 73
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Prime to narrow gene editing research as it strikes deal with Bristol Myers

BioPharma Drive: Drug Pricing

The high-profile biotech is zeroing in on programs that serve as proof points for its technology, while seeking partners for other assets.

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First data from XRISM space mission provides new perspective on supermassive black holes

Science Daily: Pharmacology News

Data from an international space mission is confirming decades worth of speculation about the galactic neighborhoods of supermassive black holes.

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Rich Text Editor in Vue Application: Using Quill.js

Perficient: Drug Development

Rich text editors are essential for many web applications, allowing users to format text, add links, and even insert media directly into their content. Quill.js is a powerful, customizable open-source editor that integrates seamlessly with modern frameworks like Vue.js. This tutorial will walk us through the steps to set up and integrate Quill.js in a Vue.js project to create a dynamic rich text editor.

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Shorter Course of Breast Cancer Radiation Won't Affect Breast Reconstruction

Drugs.com

MONDAY, Sept. 30, 2024 -- A shorter course of post-mastectomy radiation doesn't jeopardize a patient's chances of successful breast reconstruction, a new study finds.About 40 percent of people with breast cancer have mastectomies, followed by five.

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