BioPharma Drive: Drug Pricing
MARCH 8, 2024
The results have led Amylyx to pause promotion of Relyvrio and potentially pull it from the market in the coming weeks, a major blow to the company and ALS patients.
Broad Institute
MARCH 8, 2024
Study reveals genetic clusters that may explain differences in type 2 diabetes risk By Corie Lok March 8, 2024 Breadcrumb Home Study reveals genetic clusters that may explain differences in type 2 diabetes risk The clusters point to a range of biological processes that likely contribute to the development of type 2 diabetes. By Brandon Chase, Massachusetts General Hospital Communications March 8, 2024 Related content Largest and most diverse genome-wide association study of type 2 diabetes revea
Chemical Biology and Drug Design
MARCH 8, 2024
Brucine suppressed the proliferation, migration, invasion, inflammation, and macrophage M1 polarization, as well as induced apoptosis in RA-FLSs by decreasing YY1 via circ_0139658/miR-653-5p axis. Abstract Brucine is a weak alkaline indole alkaloid with wide pharmacological activities and has been identified to protect against rheumatoid arthritis (RA) process.
ASPET
MARCH 8, 2024
A problem for patients with diabetes is the rise of complications, such as peripheral neuropathy, nephropathy and retinopathy. Among them, peripheral neuropathy, characterized by numbness and/or hypersensitivity to pain in the extremities, is likely to develop in the early stages of diabetes. Empagliflozin (EMPA), a sodium-glucose cotransporter-2 inhibitor, exerts hypoglycemic effects by preventing glucose reabsorption in proximal tubular cells.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Chemical Biology and Drug Design
MARCH 8, 2024
Saikosaponin D (SSD) was used to treat pilocarpine (PP)-induced primary astrocyte injury model in rats. SSD was proved to enhance cell viability, inhibit inflammatory and oxidative stress responses, and improve mitochondrial dysfunction, thus playing a neuroprotective role in the PP-induced primary astrocyte injury model. Abstract Studies have shown that saikosaponin D (SSD) has favorable neurotherapeutic effects.
Science Daily: Pharmacology News
MARCH 8, 2024
Imagine a busy restaurant: dishes clattering, music playing, people talking loudly over one another. It's a wonder that anyone in that kind of environment can focus enough to have a conversation. A new study provides some of the most detailed insights yet into the brain mechanisms that help people pay attention amid such distraction, as well as what's happening when they can't focus.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
MARCH 8, 2024
For the first time, scientists have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- Wegovy (semaglutide), the weight-loss version of blockbuster diabetes drug Ozempic, was approved on Friday by the U.S. Food and Drug Administration to help prevent heart attack, stroke and heart death.“Wegovy is now the.
Science Daily: Pharmacology News
MARCH 8, 2024
While the majority of the world's reefs are now under threat or even damaged potentially beyond repair, a new study offers some encouraging news: efforts to restore coral reefs not only increase coral cover, but they can also bring back important ecosystem functions, and surprisingly fast.
Broad Institute
MARCH 8, 2024
A close research partnership with African scientists helps solve the mystery of malaria-like illnesses By Claire Hendershot March 8, 2024 Breadcrumb Home A close research partnership with African scientists helps solve the mystery of malaria-like illnesses Two scientists discuss how they used genetic sequencing to identify causes of malaria-mimicking infections in Senegal.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- During the past half-century, the United States’ annual number of school shootings has increased more than twelvefold, a new study finds.What’s more, children are now four times more likely to be a school shooting.
Perficient: Drug Development
MARCH 8, 2024
Have you ever wondered what happens if you connected Personalization with Sales and Service Clouds? The Personalization connector for Sales and Service Clouds exposes user data and server-side campaigns in Salesforce CRM for your contacts and leads. The Key for Success To use Personalization for Sales and Service Clouds, you’ll need to have: User identity systems fully working.
Broad Institute
MARCH 8, 2024
Machine Learning in Drug Discovery By Rose Circeo March 8, 2024 Breadcrumb Home Machine Learning in Drug Discovery Symposium Machine Learning in Drug Discovery The next Machine Learning in Drug Discovery Symposium will take place in Fall 2024. Check back soon for dates and registration. The symposium will highlight recent progress in the application of machine learning techniques to drug discovery and bring together researchers in the field that can benefit from networking.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- Ambien, Lunesta, Sonata: Millions of bleary-eyed Americans turn to this class of so-called "Z-drugs" to get restful sleep.But how do these drugs work, and do they come with risks? Experts at the U.S. Food and Drug.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
SCIENMAG: Medicine & Health
MARCH 8, 2024
University of Pittsburgh researchers have uncovered blood-based markers linked with healthy and rapid aging, allowing them to predict a person’s biological age — how fast a person’s cells and organs age regardless of their birthdate.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- Instead of approving the new Alzheimer's drug donanemab this month, as was expected, the U.S. Food and Drug Administration will now require the experimental medication be scrutinized more closely by an expert panel, the.
Science Daily: Pharmacology News
MARCH 8, 2024
When you teach a child how to solve puzzles, you can either let them figure it out through trial and error, or you can guide them with some basic rules and tips. Similarly, incorporating rules and tips into AI training -- such as the laws of physics --could make them more efficient and more reflective of the real world. However, helping the AI assess the value of different rules can be a tricky task.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- Lots of seniors are regularly taking low-dose aspirin in hopes of preventing heart attacks and strokes, even though updated guidelines often advise against it.About one in four older adults take aspirin at least three times.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Channels
MARCH 8, 2024
Today’s guest post comes from Logan Melchione, VP of Patient Affordability at Paysign. Logan discusses the evolution of patient support programs. She then outlines how these programs must evolve to stay relevant and valuable. To request an analysis of your copay savings program and learn more about Paysign’s patient affordability solutions, contact affordability@paysign.com or visit paysign.com/rx.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- Dementia could three times more common among people suffering from essential tremor, a movement disorder that causes involuntary shaking, a new study suggests.“Not only do tremors affect a person’s ability to complete.
SCIENMAG: Medicine & Health
MARCH 8, 2024
Reston, VA—A new PET radiotracer can differentiate diseased tissues from healthy tissues based on fructose metabolism, according to new research published in the March issue of The Journal of Nuclear Medicine. Fructose metabolism—or fructolysis—is indicative of a variety of diseases, and by noninvasively mapping fructolysis physicians can more accurately detect diseases and treat them earlier.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- More Americans exposed to radiation caused by the government would be compensated under a bill that passed the U.S. Senate Thursday.The bipartisan legislation, which would cost an estimated $50 billion, would expand the.
BioPharma Drive: Drug Pricing
MARCH 8, 2024
The approval makes Novo’s Wegovy the first weight-loss drug with such a claim on its prescribing information, which could have important implications for use and insurance coverage.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- Children with “lazy eye” are more likely to become adults facing an array of serious health problems, a new study warns.Kids diagnosed with amblyopia are more likely to develop high blood pressure, obesity and diabetes.
BioPharma Drive: Drug Pricing
MARCH 8, 2024
The the first of its kind move comes as pharmacy benefit managers continue to try to prove their value to clients, and shows how major players are working to meet demand for the fast-selling medicines.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- When the clocks spring forward or fall back, many folks will find themselves struggling to adjust. The transition to Daylight Saving Time can be tough on people, both mentally and physically. Research has found that people.
LifeSciVC
MARCH 8, 2024
By Robert Clarke, CEO of Kinaset, as part of the From The Trenches feature of LifeSciVC As I write, I am on the train back from New York after watching my son’s NYU basketball team play in the 2024 D3 Men’s Basketball Tournament. March Madness D3 style is a great affair as just like D1 there are 64 teams vying for a title (out of 436 D3 vs 351 D1). Alas, NYU ran into a tough Tufts team in the second round and lost a tight one 65-62.
Drug Patent Watch
MARCH 8, 2024
This chart shows the pharmaceutical companies with the most solution dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most solution dosed drugs… The post Which pharmaceutical companies have the most solution dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- It's well known that long-acting opioid meds raise the odds for addiction in users -- including folks dealing with pain after an orthopedic surgery.Now, new research suggests that patients fare just as well if doctors.
Drug Patent Watch
MARCH 8, 2024
Annual Drug Patent Expirations for ARNUITY+ELLIPTA Arnuity Ellipta is a drug marketed by Glaxosmithkline and is included in one NDA. It is available from one supplier. There are six patents… The post New patent for Glaxosmithkline drug ARNUITY ELLIPTA appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
MARCH 8, 2024
FRIDAY, March 8, 2024 -- Ever since one child, dubbed the 'Mississippi baby,' went into drug-free remission of HIV in 2013, experts have wondered if giving treatment within hours of birth might do the same for others.The results of a new trial.
Perficient: Drug Development
MARCH 8, 2024
March is not just about the arrival of spring. It’s a celebration of women’s achievements, history, and ongoing societal impact. As we continue to recognize women this month, we’re excited to take the celebration to Adobe Summit 2024! Join us on Tuesday, March 6 for our Women in Digital Breakfast at the Grand Lux Cafe in The Palazzo.
Broad Institute
MARCH 8, 2024
Next Generation Awards By Maria Nemchuk March 8, 2024 Breadcrumb Home Next Generation Awards The Next Generation Awards at the Broad Institute recognize early-career scientists (no more than 15 years after their postdoctoral position or medical residency), a group that is sometimes overlooked for funding. On average, biomedical researchers do not receive their first major grant until the age of 43.
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