Mon.Apr 29, 2024

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More plants on the menu of ancient hunter-gatherers

Science Daily: Pharmacology News

It has long been thought that meat played an important role in the diet of hunter-gatherers before the Neolithic transition. However, due to the scarcity of well-preserved human remains from Paleolithic sites, little information exists about the dietary habits of pre-agricultural human groups. A new study challenges this notion by presenting compelling isotopic evidence of a strong preference for plants among 15,000-year-old hunter-gatherers from Morocco.

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Vaccines Have Saved 154 Million Lives, Mostly Babies, Over Past 50 Years

Drugs.com

MONDAY, April 29, 2024 -- Global vaccination efforts have saved an estimated 154 million lives, including 101 million infants, a new study led by the World Health Organization (WHO) shows.Immunization has contributed more to the health and survival.

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Experimental type 1 diabetes drug shelters pancreas cells from immune system attack

Science Daily: Pharmacology News

Scientists say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals' lifespan.

Drugs 120
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5 Obtrusive Blockers to Avoid as a Servant Leader

Perficient: Drug Development

We’ve all heard of servant leadership. The concept of “being a servant” to your teams and treating employees as critical individuals to be cultivated and empowered, has strong merit. However, many organizations fall short, with those at the top of the hierarchy viewing employees as interchangeable cogs in the corporate machine. Instead of diving deep into the theories, practices, and benefits of servant leadership, I will focus on a specific, related principle or mind-set: being unobtrusive.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Microarray patches safe and effective for vaccinating children, trial suggests

Science Daily: Pharmacology News

The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses. The phase 1/2 randomized trial compared results from the measles and rubella vaccine delivered by a microarray patch, a small sticking plaster-like device with an array of microscopic projections that painlessly penetrate the skin and deliver the vaccine, or by conventional injection with a needle and syringe.

Vaccine 115
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Sustainability in pharmaceutical manufacturing: a CDMO’s contribution

BioPharma Drive: Drug Pricing

Consideration of sustainability early in process development, throughout the entire development cycle, and across the entire supply chain must also become common practice.

More Trending

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Syphilis Is Increasingly Displaying Atypical, Severe Symptoms

Drugs.com

MONDAY, April 29, 2024 -- Syphilis cases are on the rise in the United States, and doctors in Chicago say they are increasingly seeing cases that don't display typical symptoms, such as rash or skin ulcers. Instead, patients are presenting with.

Doctors 105
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Long snouts protect foxes when diving headfirst in snow

Science Daily: Pharmacology News

When hunting for mice in winter, red and arctic fox are known to plunge headfirst at speeds of 2-4 meters per second, but their sharp noses reduce the impact force in snow and protect them from injury, according to a new study.

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FDA Says First Round of Tests Show No Live Virus in Pasteurized Milk

Drugs.com

MONDAY, April 29, 2024 -- Live bird flu virus has not been found in any of the first batch of retail milk samples tested, federal health officials said Friday.Amid an ongoing outbreak of bird flu in U.S. dairy cows, the early findings should.

Virus 105
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Gemini south reveals origin of unexpected differences in giant binary stars

Science Daily: Pharmacology News

Astronomers have confirmed that differences in binary stars' composition can originate from chemical variations in the cloud of stellar material from which they formed. The results help explain why stars born from the same molecular cloud can possess different chemical composition and host different planetary systems, as well as pose challenges to current stellar and planet formation models.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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AstraZeneca, Daiichi look to broaden Enhertu use again with new study data

BioPharma Drive: Drug Pricing

The drug benefited people whose tumors have “ultralow” levels of HER2 protein, a result that could extend its reach in HER2-positive breast cancer.

Drugs 105
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Cardio-fitness cuts death and disease by nearly 20%

Science Daily: Pharmacology News

Groundbreaking new research finds that an increased cardio fitness level will reduce your risk of death from any cause by nearly 20%.

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Climate Change Could Be Good News for Viruses Like COVID

Drugs.com

MONDAY, April 29, 2024 -- Climate change -- and closed windows -- could be aiding the spread of airborne viruses like the one that causes COVID-19, a new study suggests.Increased levels of carbon dioxide in the atmosphere and in indoor spaces appear.

Virus 98
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Fixin' to be flexitarian: Scrap fish and invasive species can liven up vegetables

Science Daily: Pharmacology News

Greening the way we eat needn't mean going vegetarian. A healthy, more realistic solution is to adopt a flexitarian diet where seafoods add umami to 'boring' vegetables. A gastrophysicist puts mathematical equations to work in calculating the umami potential of everything from seaweed and shrimp paste to mussels and mackerel.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Spinal Cord Injury Damages Metabolism, and Scientists Now Know Why

Drugs.com

MONDAY, April 29, 2024 -- Patients with a spinal cord injury frequently develop diabetes and heart health problems, and researchers now think they know why.It appears that neuron activity following the injury causes belly fat to break down into.

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Scientists develop strong yet reusable adhesive from smart materials

Science Daily: Pharmacology News

Scientists have developed a smart, reusable adhesive more than ten times stronger than a gecko's feet adhesion, pointing the way for development of reusable superglue and grippers capable of holding heavy weights across rough and smooth surfaces. The research team found a way to maximize the adhesion of the smart adhesives by using shape-memory polymers, which can stick and detach easily when needed simply by heating them.

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Smokers, Former Smokers May Gain From Switch to Plant-Based Diet

Drugs.com

MONDAY, April 29, 2024 -- Current and former smokers might lower their risk for emphysema if they adopt a highly nutritional plant-based diet, a new study shows.People with a history of smoking who adopted a plant-based diet had a 56% lower risk of.

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The double-fanged adolescence of saber-toothed cats

Science Daily: Pharmacology News

How did North America's saber-toothed cats hunt without breaking their unwieldy saber-like canines, which are vulnerable to sideways bending stresses? A paleontologist provides mechanical evidence that during adolescence, when young cats were learning to hunt, their baby teeth remained in place for up to 30 months to laterally buttress the emerging permanent sabers.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Scientists Discover Cause of Rare Movement Disorder

Drugs.com

MONDAY, April 29, 2024 -- Researchers have conclusively identified the genetic cause of a rare, progressive movement disorder.A rare extra-long version of a gene appears to cause nerve cells to become poisoned by toxic proteins in people with.

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Science show’s speakers bring star power to the lab

Drug Discovery Today

The SLS Show and Conference will feature huge names in science media

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Blood Test Might Predict Knee Osteoarthritis Years Early

Drugs.com

MONDAY, April 29, 2024 -- A blood test could help doctors spot the signs of knee osteoarthritis at least eight years before it shows up on X-rays, a new study claims.After analyzing the blood of 200 white British women, half diagnosed with knee.

Doctors 98
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Probing the effects of interplanetary space on asteroid Ryugu

Science Daily: Pharmacology News

Samples reveal evidence of changes experienced by the surface of asteroid Ryugu, some probably due to micrometeoroid bombardment.

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More Medical Lab Tests Will Soon Face Federal Scrutiny, FDA Says

Drugs.com

MONDAY, April 29, 2024 -- Laboratory tests used by millions of Americans are soon to be classified as medical devices, and as such be regulated by U.S. Food and Drug Administration, the agency announced Monday.The new rule does not apply to tests.

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T. Rex not as smart as previously claimed

Science Daily: Pharmacology News

Dinosaurs were likely as smart as reptiles but not as intelligent as monkeys.

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Dogs Can Get Lyme Disease, Too

Drugs.com

MONDAY, April 29, 2024 -- People worry about contracting Lyme disease from ticks, but they should be concerned for their furry friends as well, veterinarians say.Dogs throughout the United States are increasingly vulnerable to the tick-borne.

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Astronomers' simulations support dark matter theory

Science Daily: Pharmacology News

Computer simulations by astronomers support the idea that dark matter -- matter that no one has yet directly detected but which many physicists think must be there to explain several aspects of the observable universe -- exists, according to the researchers.

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King Charles Returns to Duties After Cancer Treatment

Drugs.com

MONDAY, April 29, 2024 -- Britain's King Charles III is back to resuming his royal duties following treatment for cancer, Buckingham Palace announced Friday. "His Majesty The King will shortly return to public-facing duties after a period of.

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A Deeper Look into Protecting Wildland Firefighter Safety and Health

NIOSH Science Blog: Drugs

Wildland firefighters perform a hazardous job in dangerous conditions. Their daily tasks pose risk of burns and other heat-related injuries or illnesses; slips, trips, falls, strains, and sprains; and becoming trapped or injured by equipment or debris.1 In addition, exposures related to fighting fires—especially when it comes to smoke inhalation—have been classified as “carcinogenic,” or capable of causing cancer in humans.2 Wildland firefighters generally do not wear respirators or any other ty

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Biden Administration Delays Menthol Cigarette Ban

Drugs.com

MONDAY, April 29, 2024 -- A long-awaited ban on menthol cigarettes has been delayed indefinitely, the Biden administration said Friday.“This rule has garnered historic attention, and the public comment period has yielded an immense amount of.

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Repertoire pivot pays dividends with Bristol Myers deal

BioPharma Drive: Drug Pricing

The alliance validates the new direction pursued by Repertoire, a startup that cut staff and switched CEOs in 2022 after research on personalized cell therapies disappointed.

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ELT IS DEAD. LONG LIVE ZERO COPY.

Perficient: Drug Development

Imagine a world where we can skip Extract and Load, just do our data Transformations connecting directly to sources no matter what data platform you use? Salesforce has taken significant steps over the last 2 years with Data Cloud to streamline how you get data in and out of their platform and we’re excited to see other vendors follow their lead. They’ve gone to the next level today by announcing their more comprehensive Zero Copy Partner Network.

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Quantifying Uncertainty in RWE Studies with Quantitative Bias Analysis

Cytel

Missing data and unmeasured confounding are common challenges for researchers, particularly in observational studies and those involving real-world data, jeopardizing the validity of study conclusions. Here, we introduce a useful tool — quantitative bias analysis (QBA) — to address these challenges.

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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

Webinar | Ai At The Frontier: Empowering Early Career Professionals In Drug Discovery WEBINAR – ARE YOU CURIOUS ABOUT THE CUTTING-EDGE INTERSECTION OF ARTIFICIAL INTELLIGENCE AND DRUG DISCOVERY? Are you curious about the cutting-edge intersection of Artificial Intelligence and Drug Discovery? Join us for an insightful webinar where industry experts will delve into the transformative role of AI in revolutionising drug discovery and how it will impact your career in drug discovery.