Science Daily: Pharmacology News
APRIL 5, 2024
Certain RNA molecules in the nerve cells in the brain last a life time without being renewed. Neuroscientists have now demonstrated that this. RNAs are generally short-lived molecules that are constantly reconstructed to adjust to environmental conditions. The research group hopes to decipher the complex aging process of the brain and gain a better understanding of related degenerative diseases.
ASPET
APRIL 5, 2024
Triple Negative Breast Cancer (TNBC) is the most aggressive type of breast cancer and is associated with high probability of metastasis and poor prognosis. Chemotherapeutics and surgery remain the most common options for TNBC patients; however chemotherapeutic resistance and relapse of tumors limit the progression free survival and patient life span.
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Science Daily: Pharmacology News
APRIL 5, 2024
The CHEOPS space telescope is providing new information on the mysterious exoplanet WASP-76b. This ultra-hot giant is characterized by an asymmetry between the amount of light observed on its eastern terminator -- the fictitious line that separates its night side from its day side -- and that observed on its western terminator. This peculiarity is thought to be due to a 'glory', a luminous phenomenon similar to a rainbow, which occurs if the light from the star -- the 'sun' around which the exop
ASPET
APRIL 5, 2024
Invasive bacterial infections and sepsis are persistent global health concerns, complicated further by the escalating threat of antibiotic resistance. Over the past 40 years, collaborative endeavors to improve the diagnosis and critical care of septic patients have improved outcomes, yet grappling with the intricate immune dysfunction underlying the septic condition remains a formidable challenge.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
APRIL 5, 2024
The FDA’s clearance comes three weeks after a panel of advisers endorsed expanded use of Abecma despite safety concerns raised by the agency.
ASPET
APRIL 5, 2024
The oncogenic protein tyrosine phosphatase PTP4A3 is frequently overexpressed in human ovarian cancers and is associated with poor patient prognosis. PTP4A3 is thought to regulate multiple oncogenic signaling pathways, including STAT3, SRC, and ERK. The objective of this study was to generate ovarian cancer cells with genetically depleted PTP4A3; to assess their tumorigenicity; to examine their cellular phenotype; and to uncover changes in their intracellular signaling pathways and cytokine rele
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Target Review
APRIL 5, 2024
They appreciate and understand the host cell background A large majority of clinical and commercial proteins are generated in Chinese hamster ovary (CHO) cells. The dominance of CHO cells within the biopharma industry is a result of several beneficial characteristics displayed by these cells, including reduced susceptibility to human viruses, robust ability to proliferate on a large scale, amenability to suspension cultures, and ability to perform post-translational modifications similar to thos
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- People with HIV could have an increased risk of heart disease even if they aren’t suffering any symptoms related to their infection, a new study finds.Middle-aged people living with HIV were more likely to have early.
Drug Channels
APRIL 5, 2024
This week, I’m rerunning some popular posts while I prepare for today’s live video webinar: Drug Channel Implications of the Inflation Reduction Act. One important update: In the article below, I suggested that the IRA will make high-list/high-rebate products less attractive to Medicare plans. But this appears not be accurate, as I explain in Surprise!
BioPharma Drive: Drug Pricing
APRIL 5, 2024
The German pharmaceutical company is “streamlining” its custom-facing teams behind Cyltezo, a copycat version of AbbVie’s immune disease drug Humira.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- Suicides among U.S. college athletes have doubled over the past two years, according to data from the National Collegiate Athletic Association (NCAA).Suicide is now the second most common cause of death for college athletes.
Perficient: Drug Development
APRIL 5, 2024
In today’s hyper-competitive retail landscape, merely processing orders is no longer sufficient. Businesses need a digital commerce solution that can create immersive online experiences, drive sales, and foster long-term customer loyalty. Salesforce Commerce Cloud stands out as a game-changer in this regard, and with Perficient as your trusted partner, you can unlock its full potential.
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- As the world's population ages, a new report warns that the number of people with cancer could climb 77% by 2050.In the report, published Thursday in the journal CA: A Cancer Journal for Clinicians, researchers from.
DrugBank
APRIL 5, 2024
A landmark collaboration between the University of Tennessee Health Science Center (UTHSC), Oak Ridge National Laboratory (ORNL), and the University of Tennessee, Knoxville, secured a $20 million grant from the University of Tennessee-Oak Ridge Innovation Institute (UT-ORII). This funding is earmarked for the development of cutting-edge radiopharmaceutical therapies aimed at cancer treatment.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- A test to gauge if it's safe to prescribe a patient an addictive opioid may have been approved too soon by the U.S. Food and Drug Administration, claims a letter sent to the agency by a group of experts.The test, called.
Drug Patent Watch
APRIL 5, 2024
This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in Netherlands.
Perficient: Drug Development
APRIL 5, 2024
Have you ever tried connecting a database to AWS Glue using a JDBC SSL encryption connection? It can be quite a puzzle. A few months ago, I faced this exact challenge. I thought it would be easy, but I was wrong! When I searched for help online, I couldn’t find much useful guidance. So, I rolled up my sleeves and experimented until I finally figured it out.
Conversations in Drug Development Trends
APRIL 5, 2024
For many people, February 29th is simply Leap Day, an extraordinary date that appears only once every four years. For others, this rare day is aptly the day we honor rare disease communities. Observed annually on the last day of February since 2008, Rare Disease Day has grown into a global movement for raising awareness, promoting research, and advocating for improved access to rare disease treatments and support services.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Alta Sciences
APRIL 5, 2024
Disrupting the CRO Model: Altasciences Participates in Documentary Series for 2024 Global Health Summit aasimakopoulos Fri, 04/05/2024 - 08:21 Altasciences is leading the conversation on change in the drug development industry as part of a new documentary series for the 2024 Global Health Summit, hosted alongside the WHO’s 77th World Health Assembly in Geneva in May.
Quanticate
APRIL 5, 2024
Clinical trial professionals are well aware of the unique challenges presented by oncology, a therapeutic area dedicated to the prevention, diagnosis, and treatment of cancers. When it comes to designing Case Report Forms (CRFs) for oncology studies, considerations become more intricate due to the nature of the therapeutic area, the complexity of tests and examinations, as well as the specific data required for statistical analysis.
Perficient: Drug Development
APRIL 5, 2024
Adobe Experience Manager (AEM) is a sophisticated and versatile content management tool. Components are the elements that help structure the page, for example, the header, body, and footer, through authoring. AEM’s core components, have always allowed authors to create pages that are both efficient and simple to use, whereas developers can create components that are customizable and expandable.
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- People preparing to watch Monday’s total eclipse of the sun need to protect their vision during the event, eye doctors say.Powerful ultraviolet rays can do permanent damage to the eyes if people look directly at the sun.
Drug Patent Watch
APRIL 5, 2024
Annual Drug Patent Expirations for HETLIOZ+LQ Hetlioz Lq is a drug marketed by Vanda Pharms Inc and is included in one NDA. It is available from one supplier.
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- Overuse of marijuana is increasingly being linked to dangerous bouts of psychosis, and a new study finds that antipsychotics may be needed to keep such patients out of the hospital. Psychotic episodes involve a dangerous.
Drug Patent Watch
APRIL 5, 2024
Annual Drug Patent Expirations for HETLIOZ Hetlioz is a drug marketed by Vanda Pharms Inc and is included in two NDAs. It is available from one supplier.
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- Obese folks are less likely to benefit from a nerve-stimulation treatment for sleep apnea that’s recently been made available to them, a new study reports.The treatment is likely to be 75% less effective among obese.
Drug Patent Watch
APRIL 5, 2024
Annual Drug Patent Expirations for BRUKINSA Brukinsa is a drug marketed by Beigene and is included in one NDA. It is available from one supplier.
Cytel
APRIL 5, 2024
Written by Sydney Ringold, Customer Success Manager, and Kevin Trimm, Chief Product Officer In an ever-changing clinical development environment, sponsors face many challenges when designing clinical trials. These challenges can range from shifting regulations to growing pressure for a rapid time-to-market, and the variety of challenges can complicate trial design requirements.
Drug Patent Watch
APRIL 5, 2024
Annual Drug Patent Expirations for TALICIA Talicia is a drug marketed by Redhill and is included in one NDA. It is available from one supplier.
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- America is making headway against heart disease, with heart-related deaths declining over the past three decades.But it appears that only the well-to-do have benefitted, a new study shows.Heart attack rates have stayed the.
Reprocell
APRIL 5, 2024
The translation of preclinical findings to effective therapies requires overcoming a set of hurdles. These challenges are faced by all entities engaged in therapeutic drug discov ery. Whether they follow the traditional pharmaceutical chemistry approach or use biotechnology to manufacture new molecules, they need to identify and test promising drug candidates, and to progress them though preclinical and clinical trials to prove that they can effectively and safely meet medical needs.
Fierce BioTech
APRIL 5, 2024
Harnessing Technology in Medical Affairs: From Revealing Your Share of Voice to Pinpointing Engaged HCPs and Future Leaders swheeler Fri, 04/05/2024 - 14:15 Wed, 05/22/2024 - 10:00 Resource Type Webinar Mike Taylor Carrie Brubaker, Ph.D. Duration 60 minutes Revealing your research’s online influence and reach and identifying the correct audiences are time consuming and can pose significant challenges for Medical Affairs teams in today’s environment.
Drugs.com
APRIL 5, 2024
FRIDAY, April 5, 2024 -- People with Long COVID might be able to exercise to improve their health, something that up to now has been discouraged, a new study suggests.“The World Health Organization [WHO] and other major bodies have said that.
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