Drug Discovery Today
DECEMBER 7, 2023
A team led by Research Professor Gintautas Tamulaitis from Vilnius University Life Sciences Center (VU LSC) revealed a novel protection mechanism in CRISPR-Cas antiviral defense system. The article “Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling” was published in the journal Science.
Conversations in Drug Development Trends
DECEMBER 7, 2023
Amidst a shifting clinical landscape characterized by increasingly complex trial designs and growing patient subpopulations, many contract research organizations (CROs) have adopted a “one-stop-shop” strategic approach. As a result, various CROs have undergone significant consolidations and acquisitions of specialized capabilities to address the escalating complexity in clinical trials.
Drugs.com
DECEMBER 7, 2023
THURSDAY, Dec. 7, 2023 -- A drug long used to curb rheumatoid arthritis may be a potent foe against another immune disorder, type 1 diabetes. Australian researchers report that baricitinib (Olumiant) appears to help patients newly diagnosed with.
BioPharma Drive: Drug Pricing
DECEMBER 7, 2023
The funding is indicative of investor interest in an area of drug research that involves at least a dozen startups and multiple publicly traded companies.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Antidote
DECEMBER 7, 2023
Chronic spontaneous urticaria, also called chronic idiopathic urticaria, is a type of chronic hives that come and go unexpectedly. These hives persist daily for a minimum of six weeks without a clear cause or trigger. While this condition can affect anyone at any point, women experience it twice as often as men , and it’s most common between the ages of 20 and 40.
Science Daily: Pharmacology News
DECEMBER 7, 2023
ChatGPT may do an impressive job at correctly answering complex questions, but a new study suggests it may be absurdly easy to convince the AI chatbot that it's in the wrong.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
DECEMBER 7, 2023
An international consortium of geoscientists has reconstructed atmosphereric levels of CO2 going back 66 million years using proxies in the geoloogical record. Today's concenteration, 420 parts per million, is higher than it's ever been in 14 million years.
Drugs.com
DECEMBER 7, 2023
THURSDAY, Dec. 7, 2023 -- A drug long used to curb rheumatoid arthritis may be a potent foe against another immune disorder, type 1 diabetes.Australian researchers report that baricitinib (Olumiant) appears to help patients newly diagnosed with.
Science Daily: Pharmacology News
DECEMBER 7, 2023
A technology developed over the past few years for controlling microvehicles using ultrasound also works in the brain, as researchers have now been able to show. These microvehicles are gas bubbles, which are harmless and dissolve once their job is done. In the future, these microvehicles could be equipped with medications and deliver them to specific points in the brain.
Perficient: Drug Development
DECEMBER 7, 2023
Welcome back to our exploration of Selenium 4’s Actions API. In this second part, we’ll delve into advanced techniques and real-world applications of the enhanced Actions API. The focus will be on mouse actions, including click and release, alternate button clicks, double-clicking, moving to elements, and drag-and-drop functionalities. Additionally, we’ll provide insights into when to leverage these advanced actions and their impact on test automation.
Advertisement
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
DECEMBER 7, 2023
How heavy can an element be? An international team of researchers has found that ancient stars were capable of producing elements with atomic masses greater than 260, heavier than any element on the periodic table found naturally on Earth. The finding deepens our understanding of element formation in stars.
Practical Cheminformatics
DECEMBER 7, 2023
A recent editorial by Dean Brown in J Med Chem and follow-up posts by Keith Hornberger and Derek Lowe prompted me to think about how we train computational chemists and cheminformaticians for careers in drug discovery. It also brought to mind some unique differences between how computational chemistry is practiced in biotech and pharma. For those who haven’t read Dean Brown’s editorial and the subsequent reactions, I’d highly recommend them.
Science Daily: Pharmacology News
DECEMBER 7, 2023
Paleontologists are getting a glimpse at life over a billion years in the past based on chemical traces in ancient rocks and the genetics of living animals. New research combines geology and genetics, showing how changes in the early Earth prompted a shift in how animals eat.
SCIENMAG: Medicine & Health
DECEMBER 7, 2023
JMIR Mental Health, a premier SCIE/PubMed/Scopus-indexed, peer-reviewed journal with a unique focus on digital mental health, is inviting submissions to a new theme issue titled “Affective Computing for Mental Well-Being.
Advertisement
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
DECEMBER 7, 2023
An unexpectedly high percentage of children, who were born with HIV and started treatment within 48 hours of life, exhibit biomarkers by 2 years of age that may make them eligible to test for medication-free remission, according to a multinational study.
SCIENMAG: Medicine & Health
DECEMBER 7, 2023
A preclinical study by Weill Cornell Medicine investigators shows that a specific human genetic variant of a receptor that stimulates insulin release may help individuals be more resistant to obesity. The researchers discovered that this variant behaves differently in the cell which may contribute to more efficient metabolism.
Science Daily: Pharmacology News
DECEMBER 7, 2023
Researchers have developed an algorithm to train an analog neural network just as accurately as a digital one, enabling the development of more efficient alternatives to power-hungry deep learning hardware.
SCIENMAG: Medicine & Health
DECEMBER 7, 2023
The Allen Institute, the Chan Zuckerberg Initiative (CZI), and the University of Washington (UW) today announced the launch of the Seattle Hub for Synthetic Biology, a landmark collaboration that will build new technologies to record the history of cells over time.
Advertisement
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
DECEMBER 7, 2023
Engineers have developed a bio-compatible ink that solidifies into different 3D shapes and structures by absorbing ultrasound waves. Because the material responds to sound waves rather than light, the ink can be used in deep tissues for biomedical purposes ranging from bone healing to heart valve repair.
SCIENMAG: Medicine & Health
DECEMBER 7, 2023
Racial discrimination and bias are painful realities and increasingly recognized as detrimental to the health of adults and children. Credit: Columbia University Irving Medical Center Racial discrimination and bias are painful realities and increasingly recognized as detrimental to the health of adults and children.
Science Daily: Pharmacology News
DECEMBER 7, 2023
A study finds the greater honeyguide can learn distinct vocal signals to help people in Africa locate bee colonies. In parts of Africa, people communicate with a wild bird -- the greater honeyguide -- in order to locate bee colonies and harvest their stores of honey and beeswax. It's a rare example of cooperation between humans and wild animals, and a potential instance of cultural coevolution.
Drugs.com
DECEMBER 7, 2023
THURSDAY, Dec. 7, 2023 -- The Biden administration has again delayed enacting a ban on menthol cigarettes following intense lobbying from the tobacco industry.Along with that pressure, other critics of the ban have warned that it might anger Black.
Science Daily: Pharmacology News
DECEMBER 7, 2023
Despite the Roman Empire's extensive military and cultural influence on the nearby Balkan peninsula, a DNA analysis of individuals who lived in the region between 1 and 1000 CE found no genetic evidence of Iron Age Italian ancestry. Instead, a new study has revealed successive waves of migrations from Western Anatolia, central and northern Europe, and the Pontic-Kazakh Steppe during the Empire's reign.
Chemical Biology and Drug Design
DECEMBER 7, 2023
Cover Image © molekuul_be/Shutterstock.
Science Daily: Pharmacology News
DECEMBER 7, 2023
A recently published study puts forth a new theory that volcanic eruptions combined with widespread ocean detoxification pushed Earth's biology to a tipping point in the Late Devonian era, triggering a mass extinction.
Drug Patent Watch
DECEMBER 7, 2023
Annual Drug Patent Expirations for EXPAREL Exparel is a drug marketed by Pacira Pharms Inc and is included in one NDA. It is available from one supplier. There are eight… The post New patent for Pacira Pharms drug EXPAREL appeared first on DrugPatentWatch - Make Better Decisions.
Science Daily: Pharmacology News
DECEMBER 7, 2023
Researchers re-examined a plant fossil found decades ago in Colombia and realized that it wasn't a plant at all: it's a fossilized baby turtle. It's a rare find, because juvenile turtles' shells are soft and often don't fossilize well.
Drug Patent Watch
DECEMBER 7, 2023
Annual Drug Patent Expirations for XOPENEX+HFA Xopenex Hfa is a drug marketed by Lupin and is included in one NDA. It is available from five suppliers. There are two patents… The post New patent expiration for LUPIN drug XOPENEX HFA appeared first on DrugPatentWatch - Make Better Decisions.
Perficient: Drug Development
DECEMBER 7, 2023
Alongside our partners HCLSoftware and AWS, we hosted an automotive panel in London and invited major OEMs as well as other innovative leaders in the industry. Mark Felix, the CMO of The AA in London, was the keynote speaker followed by Martin Tavener, CTO of Commerce at HCLSoftware. I’m proud to have been a part of such an esteemed panel of colleagues as Perficient’s Automotive Industry Lead, and would love to share with you the highlights of our lively discussion.
Drug Patent Watch
DECEMBER 7, 2023
Annual Drug Patent Expirations for XPOVIO Xpovio is a drug marketed by Karyopharm Theraps and is included in one NDA. It is available from one supplier. There are eight patents… The post New patent for Karyopharm Theraps drug XPOVIO appeared first on DrugPatentWatch - Make Better Decisions.
Drug Target Review
DECEMBER 7, 2023
Predatory viruses called phages pose a great threat to bacteria, as they can infiltrate their cells to replicate and take over. Phage have been of interest to scientists as tools to understand fundamental molecular biology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. 1 Although bacteria have evolved numerous ways to counter these infections, it was previously unknown how they detect the in
Drug Patent Watch
DECEMBER 7, 2023
Annual Drug Patent Expirations for CRESEMBA Cresemba is a drug marketed by Astellas and is included in two NDAs. It is available from one supplier. There are three patents protecting… The post New patent for Astellas drug CRESEMBA appeared first on DrugPatentWatch - Make Better Decisions.
Science Daily: Pharmacology News
DECEMBER 7, 2023
The extrasolar planets Kepler-1625b and Kepler-1708b are supposedly the home worlds of the first known exomoons. A new study now comes to a different conclusion.
Expert insights. Personalized for you.
113 
Let's personalize your content