Fri.Aug 09, 2024

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Record-breaking recovery of rocks that originated in Earth's mantle could reveal secrets of planet's history

Science Daily: Pharmacology News

Scientists have recovered the first long section of rocks that originated in the Earth's mantle, the layer below the crust and the planet's largest component. The rocks will help unravel the mantle's role in the origins of life on Earth, the volcanic activity generated when it melts, and how it drives the global cycles of important elements such as carbon and hydrogen.

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With pharma in ‘catbird seat,’ biotechs get less upfront in drug partnerships

BioPharma Drive: Drug Pricing

Recent data from J.P. Morgan indicates early-stage startups are getting smaller upfront payments in alliances than a few years ago, a trend industry insiders attribute to weaker leverage in deal talks.

Drugs 315
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Bacteria encode hidden genes outside their genome--do we?

Science Daily: Pharmacology News

A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.

Therapies 358
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In tone-setting verdict, FDA rejects MDMA as a therapy aid for PTSD

BioPharma Drive: Drug Pricing

The decision to turn down an application from Lykos Therapeutics comes at a pivotal time for psychedelics research, which, after decades of dismissal, has recently gained momentum.

Therapies 311
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Study reveals ways in which 40Hz sensory stimulation may preserve brain's 'white matter'

Science Daily: Pharmacology News

Scientists report that gamma frequency light and sound stimulation preserves myelination in mouse models and reveal molecular mechanisms that may underlie the benefit.

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More Trending

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Potential new approach to enhancing stem-cell transplants

Science Daily: Pharmacology News

A discovery may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells.

Disease 337
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Merck bets $700M on an antibody drug’s potential in immune diseases

BioPharma Drive: Drug Pricing

The deal hands Merck a cancer medicine already in human testing, but that the company sees as a potential treatment for autoimmune conditions, too.

Disease 280
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Millions of years for plants to recover from global warming

Science Daily: Pharmacology News

Catastrophic volcanic eruptions that warmed the planet millions of years ago shed new light on how plants evolve and regulate climate. Researchers reveal the long-term effects of disturbed natural ecosystems on climate in geological history and its implications for today.

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Childhood Vaccines Have Saved 1 Million U.S. Lives Since 1994, CDC Says

Drugs.com

FRIDAY, Aug. 9, 2024 -- In findings that offer compelling evidence of the power of childhood vaccines, a new government report shows the routine shots have prevented hundreds of millions of illnesses, tens of millions of hospitalizations and more.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Largest protein yet discovered builds algal toxins

Science Daily: Pharmacology News

While seeking to unravel how marine algae create their chemically complex toxins, scientists have discovered the largest protein yet identified in biology. Uncovering the biological machinery the algae evolved to make its intricate toxin also revealed previously unknown strategies for assembling chemicals, which could unlock the development of new medicines and materials.

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New Upright Scanner Tracks Brain Function While You Walk

Drugs.com

FRIDAY, Aug. 9, 2024 -- A wearable brain scanner could improve research into Parkinson’s disease, dementia and other debilitating disorders, new research shows.The brain scanner -- called the Ambulatory Motion-enabling PET (AMPET) -- fits on a p.

Disease 246
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New technology uses light to engrave erasable 3D images

Science Daily: Pharmacology News

Researchers invented a technique that uses a specialized light projector and a photosensitive chemical additive to imprint two- and three-dimensional images inside any polymer. The light-based engraving remains in the polymer until heat or light are applied, which erases the image and makes it ready to use again. The technology is intended for any situation where having detailed, precise visual data in a compact and easily customizable format could be critical, such as planning surgeries and dev

Research 313
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How Likely Is It That Autism Recurs in One Family?

Drugs.com

FRIDAY, Aug. 9, 2024 -- There’s a good chance that if one child in a family has autism, another will also develop the disorder, a new study suggests.Children are seven times more likely to be diagnosed with autism if an older sibling has the d.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Greenland mega-tsunami led to week-long oscillating fjord wave

Science Daily: Pharmacology News

In September 2023, a megatsunami in remote eastern Greenland sent seismic waves around the world, piquing the interest of the global research community. The event created a week-long oscillating wave in Dickson Fjord, according to a new report in The Seismic Record.

Research 284
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FDA Approves First Nasal Spray to Curb Anaphylaxis, An Alternative to Injections

Drugs.com

FRIDAY, Aug. 9, 2024 -- People who are nervous about administering a rescue shot for anaphylaxis finally have a new alternative in a nasal spray.The U.S. Food and Drug Administration on Friday announced that it has approved neffy, the first.

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Establishing Effective Adaptive Trial Designs for Oncology in Multi-Regional Studies

Conversations in Drug Development Trends

Authors: Matt Cooper, PhD, Executive Director, Therapeutic Strategy Lead, Oncology; Megan Morrison, Vice President, Asia Pacific Strategy Lead Adaptive trial designs have become essential in oncology, offering a flexible and efficient approach for conducting clinical trials. By allowing protocol adjustments based on interim data analysis, these designs preserve the integrity of studies while effectively addressing the unique challenges of multi-regional clinical trials (MRCTs).

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Diabetes Run in Your Family? Diet, Exercise Can Still Prevent It

Drugs.com

FRIDAY, Aug. 9, 2024 -- Folks can overcome their genetic risk for type 2 diabetes through healthy diet and regular exercise, a new study says.A healthy lifestyle reduced the risk of type 2 diabetes by 70% among a group of people with a high genetic.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Investment Trends in Pharmaceutical Research

DrugBank

Investment Trends in Pharmaceutical Research and Development Investing in the pharmaceutical sector presents a unique set of challenges and opportunities; let’s examine them in more detail.  The average cost of bringing a new drug to market is about $2.6 billion, with a development timeline spanning 10 to 15 years. Moreover, the probability of success for a drug candidate entering clinical trials is only around 10%, highlighting the substantial risks involved.

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Hospital Patients Can Bring 'Superbugs' Home

Drugs.com

FRIDAY, Aug. 9, 2024 -- Patients discharged from a hospital stay are bringing antibiotic-resistant “superbugs” home with them, a new study warns.Family members of recently discharged patients are 71 times more likely to get a MRSA infection after th.

Hospitals 246
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UX in Universal Design Series: The Importance of Large Touch Targets in Health Systems – 5

Perficient: Drug Development

Welcome to another insightful installment in our UX in Universal Design series! This time, we’ll be focusing on the importance of large touch targets within health systems. As healthcare increasingly relies on digital interfaces—whether through patient portals, check-in kiosks, or mobile health apps—it’s crucial to ensure that these technologies are accessible to all users, including those with physical disabilities or dexterity challenges.

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TikTok Videos Glamorize Eating Disorders and Harm Women's Body Image

Drugs.com

FRIDAY, Aug. 9, 2024 -- Women exposed to TikTok videos that make eating disorders look cool and glamorous tend to have worse body image, a new study finds.These videos include what researchers call "pro-anorexia" clips, as well as other videos.

Research 241
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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FDA’s Diversity Action Plan: Questions, answers, and what we (don’t) know so far

Agency IQ

By Laura DiAngelo, MPH Last month, the FDA published a new draft guidance document on diversity action plans. While the new version of the guidance is greatly expanded as compared to an earlier version from 2022, it has left plenty of important questions unanswered. In this piece, AgencyIQ answers some of the most common questions we’ve received about the guidance – and raise a few of our own.

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FDA Approves First Nasal Spray, Neffy, to Curb Anaphylaxis, An Alternative to Injections

Drugs.com

FRIDAY, Aug. 9, 2024 -- People who are nervous about administering a rescue shot for anaphylaxis finally have a new alternative in a nasal spray. The U.S. Food and Drug Administration on Friday announced that it has approved neffy, the first.

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FDA’s new metabolic diseases committee gives hesitant nod to ultra-rare disease drug

Agency IQ

By Amanda Conti In its inaugural meeting, FDA’s Genetic Metabolic Diseases Advisory Committee heard Zevra’s second try for arimoclomol to treat ultra-rare lysosomal storage disorder Niemann-Pick Type C. The committee voted 11-5 in favor of the drug’s effectiveness, leaving FDA to test the limits of its regulatory flexibility toward post hoc analysis and lackluster confirmatory evidence.

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Post-Op Radiation May Give Long-Term Protection Against Breast Cancer's Return

Drugs.com

FRIDAY, Aug. 9, 2024 -- Radiation therapy following surgery can keep breast cancer from returning for up to 10 years, a new study claims.The study supports the current standard of care for early-stage breast cancer, which involves surgery followed.

Therapies 130
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EMA’s psychedelic workshop leaves stakeholders with as many questions as answers

Agency IQ

By Sebastian Godoy, MPH Earlier this year, the EMA hosted a multi-stakeholder workshop to discuss regulatory issues surrounding drug development of psychedelic products. Despite intense interest in their use, no psychedelic products are approved in the European Regulatory Medicines Network, with drug developers facing legal and regulatory obstacles, including a dearth of guidance.