National Institute on Drug Abuse: Nora's Blog

FEBRUARY 1, 2024

50 years after founding, NIDA urges following science to move beyond stigma area Thu, 02/01/2024 - 11:20 Nora's Blog February 1, 2024 Image NIDA Image In 2024, NIDA celebrates its 50th anniversary. On May 14, 1974, an act of Congress established the National Institute on Drug Abuse (NIDA), and since then NIDA has led the world in funding and conducting research on drug use and addiction.

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Science FDA Approval Treatment Research 130

Science Daily: Pharmacology News

FEBRUARY 1, 2024

It's an achievement with important implications for scientists studying the brain and working on treatments for a broad range of neurological and neurodevelopmental disorders, such as Alzheimer's and Parkinson's disease.

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Research Treatment Disease 130

Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- Certain copycat eyedrops may be contaminated and could give users an antibiotic-resistant eye infection, the U.S. Food and Drug Administration warned Wednesday.The packaging for South Moon, Rebright and FivFivGo eyedrops.

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Packaging FDA Drugs 116

Science Daily: Pharmacology News

FEBRUARY 1, 2024

Researchers have discovered a change in what scientists already knew about global warming dynamics. It had been widely accepted since the 1950s that global temperature rises were not consistent throughout the day and night, with greater nighttime warming being observed. However, the recent study reveals a shift in dynamics: with greater daytime warming taking place since the 1990s.

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Research 127

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

BioPharma Drive: Drug Pricing

FEBRUARY 1, 2024

Roche said it was shelving those drugs in favor of experimental programs to treat obesity that it gained from its takeover of Carmot Therapeutics.

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Drugs 119

Science Daily: Pharmacology News

FEBRUARY 1, 2024

Scientists developed a new method to map exactly how a fungus works with leafcutter ants in a complex microbial community to degrade plant material at the molecular level. The team's insights are important for biofuels development.

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Drug Target Review

FEBRUARY 1, 2024

What challenges has the industry faced in developing and commercialising treatments for neurological diseases, including rare diseases? It’s a great question, because the challenges are numerous and it’s a very tough therapeutic area. But commitment to neuroscience drug development is critically important given the significant unmet medical needs and the ways in which patients, caregivers, and families suffer.

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Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- Americans are terribly lonely, a new poll reveals.Among U.S. adults, about one in three said they feel lonely at least once a week. Worse, one in 10 Americans say they feel lonely every day, results show.Younger people are.

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BioPharma Drive: Drug Pricing

FEBRUARY 1, 2024

François-Xavier Roger will replace current CFO Jean-Baptiste Chasseloup de Chatillon as Sanofi continues a research pivot and cost-cutting drive.

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Research 107

PLOS: DNA Science

FEBRUARY 1, 2024

Five people treated for pituitary dwarfism decades ago with human growth hormone (hGH) pooled from cadavers have shown cognitive decline reminiscent of early-onset Alzheimer’s disease. Their dementia likely arose from transmission of the bits of amyloid-beta protein that lie behind Alzheimer’s delivered along with the needed hormone, initiating a molecular chain reaction that led to brain effects decades later.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- A walk in the woods appears to sharpen the mind better than an urban asphalt amble, a new brain scan study finds.People strolling through an arboretum at the University of Utah performed better on brain function tests than.

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SCIENMAG: Medicine & Health

FEBRUARY 1, 2024

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor functions, which eventually leads to death within 5 years of its onset. This disease causes weakness and atrophy of limbs and other muscles, which affect mobility speech, eating, and even breathing in patients.

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Clinical Trials Trials Disease Drugs 90

Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- A person's odds for a dementia diagnosis nearly triple in the first year after a stroke, new research shows.This post-stroke spike in dementia risk does subside with time, but it never returns to pre-stroke levels, the.

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Research 98

BioPharma Drive: Drug Pricing

FEBRUARY 1, 2024

The agreement gives Protagonist an experienced hand in Takeda, which can help the former commercialize its product.

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Licensing Licensing Production Drugs 111

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- Radon, an invisible, naturally occurring radioactive gas, appears to raise a person’s risk of stroke, a new study suggests.Already known as the second leading cause of lung cancer, these new findings suggest exposure to.

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SCIENMAG: Medicine & Health

FEBRUARY 1, 2024

A large multicenter clinical trial co-led by University of Maryland School of Medicine researchers large multicenter clinical trial co-led by University of Maryland School of Medicine researchers found that an antiseptic containing iodine resulted in about one-quarter fewer post-surgical infections in patients with limb fractures compared to another frequently used skin antiseptic.

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Clinical Trials Trials Research 86

Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- Women with a common ovarian disorder might be more likely to have memory and thinking problems in middle age, a new study suggests.Females diagnosed with polycystic ovary syndrome (PCOS) scored lower on cognitive tests.

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SCIENMAG: Medicine & Health

FEBRUARY 1, 2024

Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication posing significant health risks to both mothers and their newborns. Early detection and treatment of GDM are crucial to prevent adverse outcomes. Current screening methods, like glucose tolerance tests, are in after 24 weeks of pregnancy and have limitations in patient compliance and accuracy.

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Compliance Treatment 86

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- A new study of aging U.S. veterans finds that one in every 10 who have been diagnosed with dementia might actually have brain impairments caused by liver cirrhosis.It's a condition called hepatic encephalopathy, and it's.

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SCIENMAG: Medicine & Health

FEBRUARY 1, 2024

Adoption can be challenging for man’s best friend, and Virginia Tech researchers are exploring ways to make the process better for dogs in animal shelters and increase community involvement.

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Research 84

Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- A much anticipated government study finds that military personnel stationed at Camp Lejeune in North Carolina between 1975 and 1985 face at least a 20% higher risk for certain cancers than those stationed elsewhere. Why.

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Government 103

Science Daily: Pharmacology News

FEBRUARY 1, 2024

We often think of fish as carefree swimmers in the ocean, reacting to the world around them without much forethought. However, new research suggests that our marine cousins may be more cognizant than we credit them for. Fish may be counting vertical bars on intruders to determine their threat level, and to inform the social hierarchy governing their sea anemone colonies.

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Government Research 89

Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- Losing the use of an arm after a stroke can be devastating, but new research could offer survivors fresh hope.The study found that a combination of targeted brain stimulation therapy, along with intense physical.

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Therapies Research 96

Covalent Modifiers

FEBRUARY 1, 2024

Mir, M.H., Parmar, S., Singh, C. et al. Nat Commun 15 , 859 (2024). [link] Proteins labelled site-specifically with small molecules are valuable assets for chemical biology and drug development. The unique reactivity profile of the 1,2-aminothiol moiety of N -terminal cysteines ( N -Cys) of proteins renders it highly attractive for regioselective protein labelling.

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Biophysical Assays Small Molecule Drug Development Production 79

Drugs.com

FEBRUARY 1, 2024

FRIDAY, Feb. 2, 2024 -- Black American women have much higher rates of high blood pressure than white women, and it's especially deadly if hypertension sets in before the age of 35, new research shows.Black women diagnosed with high blood pressure.

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Research 96

SCIENMAG: Medicine & Health

FEBRUARY 1, 2024

INDIANAPOLIS—An Indiana University School of Medicine surgeon-scientist is leading a multi-institutional grant investigating the role of the sinus microbiome in chronic rhinosinusitis, an inflammatory disease that causes the lining of the sinuses to swell. The research team will study biospecimens from human sinus surgery patients in the lab and examine how bacteria in the microbiome shape the disease process and might offer novel therapeutic strategies.

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Disease Research 77

addgene Blog

FEBRUARY 1, 2024

Addgene is excited to announce we now offer an export license application for rabies materials! Some of the materials in our repository, including rabies plasmids, are export-controlled materials in the USA, where Addgene is located. The export license, if granted, allows us to ship rabies plasmids and viral vectors containing genetic elements from rabies plasmids to international requestors.

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Licensing Licensing International 72

BioPharma Drive: Drug Pricing

FEBRUARY 1, 2024

The company is open to deals the size of its prior Acceleron and Prometheus buyouts. “We continue to believe we need more,” CEO Rob Davis said.

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Covalent Modifiers

FEBRUARY 1, 2024

Skye Montoya et al. Science 383 , eadi5798 (2024). DOI: 10.1126/science.adi5798 Structured Abstract INTRODUCTION Bruton’s tyrosine kinase (BTK) is a nonreceptor kinase in the B cell receptor (BCR) signaling cascade critical for B cell survival. As such, chronic lymphocytic leukemia (CLL) and other B cell cancers are sensitive to inhibition of BTK. Covalent and noncovalent inhibitors of BTK have revolutionized the treatment of these cancers.

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Targeted Protein Degradation Clinical Trials Trials Science 68

Drug Patent Watch

FEBRUARY 1, 2024

Annual Drug Patent Expirations for NOCDURNA Nocdurna is a drug marketed by Ferring Pharms Inc and is included in one NDA. It is available from one supplier. There are ten… The post New patent expiration for Ferring Pharms drug NOCDURNA appeared first on DrugPatentWatch - Make Better Decisions.

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Perficient: Drug Development

FEBRUARY 1, 2024

SCOPE is only a few weeks away! The conference will take place on February 11-14, 2024, in Orlando, Florida. Still not registered? Click here ! The SCOPE (Summit for Clinical Ops Executives) conference is a premier event in the field of clinical operations, providing a comprehensive platform for professionals to explore the latest trends and innovations in clinical research.

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Drug Patent Watch

FEBRUARY 1, 2024

Annual Drug Patent Expirations for IMBRUVICA Imbruvica is a drug marketed by Pharmacyclics Llc and is included in three NDAs. It is available from one supplier. There are forty-one patents… The post New patent for Pharmacyclics Llc drug IMBRUVICA appeared first on DrugPatentWatch - Make Better Decisions.

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NIOSH Science Blog: Drugs

FEBRUARY 1, 2024

The National Institute for Occupational Safety and Health (NIOSH) Nanotechnology Research Center (NTRC) has taken on a global leadership role on research and guidance for nanomaterials in the workplace since the formation of NTRC in 2004 [1]. Global Collaborations is one of the ten critical topic areas for nanotechnology research and communication identified by NTRC [2].

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