Mon.Dec 09, 2024

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Nobel Prize celebrates AI’s role in protein structure innovation

Drug Target Review

The 2024 Nobel Prize in Chemistry was awarded to Demis Hassabis and John Jumper from Google DeepMind for developing AlphaFold2, and to David Baker from the University of Washington for his work in computational protein design. These innovations have revolutionised the understanding of protein structures using artificial intelligence. Before AlphaFold, determining 3D protein structures was complex and time-consuming, and often required the use of experimental methods like X-ray crystallography an

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EXPRESSION OF CONCERN: The Truncated Human Telomeric Sequence Forms a Hybrid‐Type Intramolecular Mixed Parallel/antiparallel G‐quadruplex Structure in K+ Solution

Chemical Biology and Drug Design

EXPRESSION OF CONCERN: Y. Liu, D. Cheng, M. Ge, and W. Lin, The Truncated Human Telomeric Sequence Forms a Hybrid-Type Intramolecular Mixed Parallel/antiparallel G-quadruplex Structure in K+ Solution, Chemical Biology & Drug Design 88, no. 1 (2016): 122-128, [link]. This Expression of Concern is for the above article, published online on 12 February 2016, in Wiley Online Library ( [link] ), and has been issued by agreement between the journal Editor-in-Chief, Roberta Melander; and John Wiley

Drugs 100
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Pharmacognosy and Drug Patents: Unveiling Nature’s Medicinal Treasures

Drug Patent Watch

In the vast realm of pharmaceutical research and development, there’s a fascinating intersection between ancient wisdom and modern science. This intersection is where pharmacognosy meets drug patents, creating a unique landscape that shapes the future of medicine. But what exactly is pharmacognosy, and how does it relate to the complex world of drug patents?

Drugs 84
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The Evolving Landscape of Quality Management Systems in Life Sciences

thought leadership

In the decades since the FDA first introduced Good Manufacturing Practice (GMP) regulations, the drug and device industry has undergone significant transformation. While the core principles of GMPsafety, efficacy, and qualityremain foundational, the way manufacturers achieve these goals has evolved to keep pace with increasing complexity. Today's manufacturing environment is shaped by the rise of advanced therapies, including biologics, cell and gene therapies , and personalized medicine, each d

Science 75
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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TrialKit AI: Revolutionizing Clinical Research Analytics with AI

Crucial Data Solutions

December 9, 2024— Crucial Data Solutions is proud to announce that our groundbreaking innovation, TrialKit AI, has been recognized with. The post TrialKit AI: Revolutionizing Clinical Research Analytics with AI appeared first on Crucial Data Solutions.

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Overcoming challenges in biosimilar analytical characterization

Drug Patent Watch

Biosimilars have faced significant challenges in their analytical characterization. This process involves a comprehensive analysis of the biosimilar’s molecular structure, biological activity, and other quality characteristics to demonstrate similarity to the reference product. The emphasis on analytical and functional testing through sophisticated technology is crucial in overcoming these challenges.

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HPM and Riparian to Co-Host Webinar on CMS Misclassification Penalties Rule

FDA Law Blog: Biosimilars

On Wednesday, December 11, Hyman, Phelps & McNamara, P.C. (HPM) and Riparian LLC will co-host a webinar on an important CMS rule imposing penalties for misclassification of drugs and other reporting errors under the Medicaid Drug Rebate Program. (See our post on this rule here.) The Webinar will explore the CMS rule and provide actionable recommendations for manufacturers on how to navigate the new requirements.

Drugs 59
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Managing Dependencies for Test Automation with requirements.txt

Perficient: Drug Development

When it comes to test automation in Python, managing your dependencies is essential for ensuring consistent and reliable test execution. One of the most effective ways to handle these dependencies is through the requirements.txt file. In this blog post, well discuss what requirements.txt is, its importance in the context of testing, and how to effectively use it to streamline your test automation workflow.

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Women in STEM with Stella Vnook

Drug Target Review

Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My journey into STEM began with a strong passion for science and a curiosity about how to do things differently, including a drive to explore new paths to treating a disease, as well as new solutions to problems that plague the biopharma space. I have spent nearly 30 years of my career advancing healthcare and biotechnology.

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Lifecycle Hooks in LWC

Perficient: Drug Development

In Salesforce Lightning Web Components (LWC), lifecycle hooks play a crucial role in defining the behavior of components at various stages of their lifecycle. Whether you’re a seasoned developer or just getting started, understanding lifecycle hooks can significantly enhance how you build efficient and interactive applications. Lets dive deep into what they are, their real-world use cases, and how they can help you write better code.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Dependency Injection in Salesforce

Perficient: Drug Development

In modern software development, design patterns play a crucial role in building scalable and maintainable applications. One such powerful pattern is Dependency Injection (DI). While its widely recognized in other programming paradigms, DI can also be effectively utilized in Salesforce to promote clean, modular, and testable code. Whether you’re a seasoned Salesforce developer or just starting your journey, understanding and implementing Dependency Injection can elevate your application des

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Salesforce Einstein Trust Layer: Your Data’s Shield

Perficient: Drug Development

In todays world, where Artificial Intelligence (AI) is making waves in almost every industry, one of the most pressing concerns for organizations is their data security. This concern grows significantly when leveraging AI tools like Einstein Generative AI, which interacts with actual customer data. Ensuring the safety, privacy, and integrity of that data is paramount.

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Perficient Hosts Mark Cuban Foundation AI Bootcamps to Inspire Future STEM Leaders

Perficient: Drug Development

For the fourth consecutive year, Perficient has partnered with the Mark Cuban Foundation to offer free AI Bootcamps to underserved high school students across the United States. Held over the first three Saturdays of November, this initiative works to inspire the next generation of leaders in Artificial Intelligence and Machine Learning, providing them with hands-on training and experience to succeed in the ever-evolving tech landscape.

Science 52
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Perficient Recognized in The Forrester Wave™: CX Strategy Consulting Services, Q4 2024

Perficient: Drug Development

Perficient Recognized in The Forrester Wave : Customer Experience Strategy Consulting Services, Q4 2024 Perficient is proud to be included as a Contender in The Forrester Wave : Customer Experience (CX) Strategy Consulting Services, Q4 2024 report. We were one of a set of only twelve organizations to be included in the report. Forrester used extensive criteria to determine placement, including customer research, proprietary data offerings, and innovation.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Perficient Recognized in The Forrester Wave™: CX Strategy Consulting Services, Q4 2024

Perficient: Drug Development

Perficient Recognized in The Forrester Wave : Customer Experience Strategy Consulting Services, Q4 2024 Perficient is proud to be included as a Contender in The Forrester Wave : Customer Experience (CX) Strategy Consulting Services, Q4 2024 report. We were one of a set of only twelve organizations to be included in the report. Forrester used extensive criteria to determine placement, including customer research, proprietary data offerings, and innovation.