Mon.Dec 09, 2024

article thumbnail

Nobel Prize celebrates AI’s role in protein structure innovation

Drug Target Review

The 2024 Nobel Prize in Chemistry was awarded to Demis Hassabis and John Jumper from Google DeepMind for developing AlphaFold2, and to David Baker from the University of Washington for his work in computational protein design. These innovations have revolutionised the understanding of protein structures using artificial intelligence. Before AlphaFold, determining 3D protein structures was complex and time-consuming, and often required the use of experimental methods like X-ray crystallography an

article thumbnail

Pharmacognosy and Drug Patents: Unveiling Nature’s Medicinal Treasures

Drug Patent Watch

In the vast realm of pharmaceutical research and development, there’s a fascinating intersection between ancient wisdom and modern science. This intersection is where pharmacognosy meets drug patents, creating a unique landscape that shapes the future of medicine. But what exactly is pharmacognosy, and how does it relate to the complex world of drug patents?

Drugs 92
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

EXPRESSION OF CONCERN: The Truncated Human Telomeric Sequence Forms a Hybrid‐Type Intramolecular Mixed Parallel/antiparallel G‐quadruplex Structure in K+ Solution

Chemical Biology and Drug Design

EXPRESSION OF CONCERN: Y. Liu, D. Cheng, M. Ge, and W. Lin, The Truncated Human Telomeric Sequence Forms a Hybrid-Type Intramolecular Mixed Parallel/antiparallel G-quadruplex Structure in K+ Solution, Chemical Biology & Drug Design 88, no. 1 (2016): 122-128, [link]. This Expression of Concern is for the above article, published online on 12 February 2016, in Wiley Online Library ( [link] ), and has been issued by agreement between the journal Editor-in-Chief, Roberta Melander; and John Wiley

Drugs 100
article thumbnail

Overcoming challenges in biosimilar analytical characterization

Drug Patent Watch

Biosimilars have faced significant challenges in their analytical characterization. This process involves a comprehensive analysis of the biosimilar’s molecular structure, biological activity, and other quality characteristics to demonstrate similarity to the reference product. The emphasis on analytical and functional testing through sophisticated technology is crucial in overcoming these challenges.

article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Existing EV batteries may last up to 40% longer than expected

Science Daily: Pharmacology News

93
article thumbnail

ASH24: Darzalex in smoldering myeloma, Merck’s ADC data and Novo’s sickle cell drug

BioPharma Drive: Drug Pricing

Drugs 89

More Trending

article thumbnail

Gene therapy uptake in sickle cell stays slow, despite patient interest

BioPharma Drive: Drug Pricing

article thumbnail

Short-term cognitive boost from exercise may last for 24 hours

Science Daily: Pharmacology News

86
article thumbnail

One Type of Blood Pressure Med May Help Prevent Post-Stroke Epilepsy

Drugs.com

85
article thumbnail

Dogs use two-word button combos to communicate

Science Daily: Pharmacology News

86
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

EPA Bans Two Solvents Linked to Cancer

Drugs.com

84
article thumbnail

Earliest deep-cave ritual compound in Southwest Asia discovered

Science Daily: Pharmacology News

86
article thumbnail

Why bioscience and healthcare innovators are looking to Phoenix

BioPharma Drive: Drug Pricing

80
article thumbnail

Not so simple machines: Cracking the code for materials that can learn

Science Daily: Pharmacology News

85
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Keto Diet Supplement Could Boost a Cancer Treatment's Effectiveness

Drugs.com

article thumbnail

Black hole debate settled? Stellar-mass black holes found at the heart of the Milky Way's largest star cluster

Science Daily: Pharmacology News

85
article thumbnail

High-Fiber Diet May Prevent a Blood Cancer in People at High Risk

Drugs.com

75
article thumbnail

New AI cracks complex engineering problems faster than supercomputers

Science Daily: Pharmacology News

article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

1 in 3 Older Americans Say They Feel Lonely, Poll Finds

Drugs.com

75
article thumbnail

New ocean predator discovered in the Atacama Trench

Science Daily: Pharmacology News

84
article thumbnail

Dolphins Are Testing Positive for Fentanyl

Drugs.com

75
article thumbnail

Astronomers find the smallest asteroids ever detected in the main belt

Science Daily: Pharmacology News

84
article thumbnail

Q&A: How a Broad team uses cutting-edge spatial technologies to enable new science

Broad Institute

Science 74
article thumbnail

Pups of powerful meerkat matriarchs pay a price for their mom's status

Science Daily: Pharmacology News

81
article thumbnail

Dimension gets $500M to bankroll biotech’s convergence with tech

BioPharma Drive: Drug Pricing

72
article thumbnail

Space-time crystals, an important step toward new optical materials

Science Daily: Pharmacology News

79
article thumbnail

The Evolving Landscape of Quality Management Systems in Life Sciences

thought leadership

In the decades since the FDA first introduced Good Manufacturing Practice (GMP) regulations, the drug and device industry has undergone significant transformation. While the core principles of GMPsafety, efficacy, and qualityremain foundational, the way manufacturers achieve these goals has evolved to keep pace with increasing complexity. Today's manufacturing environment is shaped by the rise of advanced therapies, including biologics, cell and gene therapies , and personalized medicine, each d

Science 75
article thumbnail

How 'Conan the Bacterium' withstands extreme radiation

Science Daily: Pharmacology News

69
article thumbnail

TrialKit AI: Revolutionizing Clinical Research Analytics with AI

Crucial Data Solutions

December 9, 2024— Crucial Data Solutions is proud to announce that our groundbreaking innovation, TrialKit AI, has been recognized with. The post TrialKit AI: Revolutionizing Clinical Research Analytics with AI appeared first on Crucial Data Solutions.

article thumbnail

Mars' infamous dust storms can engulf the entire planet: A new study examines how

Science Daily: Pharmacology News

67
article thumbnail

Endometriosis drug research, long underfunded, confronts familiar problems in women’s health

BioPharma Drive: Drug Pricing

article thumbnail

Structure-Based Discovery of a Series of Covalent, Orally Bioavailable, and Selective BFL1 Inhibitors

Covalent Modifiers

49
article thumbnail

Humira Biosimilar Price War Update: Should We Be Glad that CVS Health and Express Scripts Are Using Private Label Products to Pop the Gross-to-Net Bubble? (rerun)

Drug Channels

This week, Im rerunning some popular posts while I prepare for Fridays Drug Channels Outlook 2025 live video webinar. Click here to see the original post. During Friday's webinar, Ill share some updated thoughts on biosimilars and PBMs private label products. The Humira biosimilar market just took another step forwardbut remains far from its ideal state.