Drug Discovery World

JULY 9, 2024

The Scottish Medicines Consortium (SMC) has published final advice on two rare disease therapies. Elfabrio (pegunigalsidase alfa), a novel enzyme replacement therapy (ERT), has been approved as a treatment option for Fabry disease in adults. Also, birch bark extract gel has been approved as a treatment option for junctional and dystrophic epidermolysis bullosa (EB), subject to data collection under the SMC’s ultra-orphan medicines framework.

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Science Daily: Pharmacology News

JULY 9, 2024

The United States has lost its only stand of the massive Key Largo tree cactus in what researchers believe is the first local extinction of a species caused by sea level rise in the country.

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Research 126

Drug Discovery World

JULY 9, 2024

Researchers at the Francis Crick Institute have mapped all the possible outcomes of changes to a tumour-suppressing gene called VHL. The VHL map could help clinicians work out which patients are at risk of developing kidney cancer or might respond to certain drugs. It is the first step in a huge research endeavour to unpick the outcomes of tens of thousands of genetic variations in genes associated with cancer.

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Laboratories Research Treatment Drugs 147

BioPharma Drive: Drug Pricing

JULY 9, 2024

The company has begun searching for a successor to Dolsten, who oversaw more than 35 drug and vaccine approvals but also some notable setbacks during his time as Pfizer’s top scientist.

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Research Vaccine Drugs 120

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

JULY 9, 2024

UK biotech Myricx Bio has raised £90 ($114) million Series A financing to support the development of its N-Myristoyltransferase inhibitor (NMTi) antibody-drug conjugate (ADC) therapeutics. The round was co-led by new investors Novo Holdings and Abingworth, with additional support from British Patient Capital, Cancer Research Horizons and Eli Lilly, plus founding investors Brandon Capital and Sofinnova Partners.

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Small Molecule Laboratories Drugs Research 147

Science Daily: Pharmacology News

JULY 9, 2024

A international team of astronomers has made an exciting discovery about the temperate exoplanet LHS 1140 b: it could be a promising 'super-Earth' covered in ice or water.

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International 118

Science Daily: Pharmacology News

JULY 9, 2024

New research has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing effective pain relief.

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Research Drugs 117

addgene Blog

JULY 9, 2024

What's new in Addgene's ready-to-use viral vectors repository? Quite a bit! In this post, we'll share the 20 additions we've made to our viral vectors repository since March.

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Science Daily: Pharmacology News

JULY 9, 2024

Age data for certain classes of meteorite have made it possible to gain new findings on the origin of small water-rich astronomical bodies in the early solar system. These planetesimals continually supplied building materials for planets -- also for the Earth, whose original material contained little water. The Earth received its actual water through planetesimals, which emerged at low temperatures in the outer solar system, as shown by computational models carried out by an international resear

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International Research 111

Drug Target Review

JULY 9, 2024

For the first time, scientists at UCL and University Medical Center Utrecht have observed bowel cancer cells’ ability to regulate their growth using a genetic on-off switch to increase their likelihood of survival. These results could pave the way for personalised cancer medicine, determining how aggressive a patient’s cancer is, and selecting the most effective therapeutics.

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Regulations DNA Treatment Research 105

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Science Daily: Pharmacology News

JULY 9, 2024

A newly discovered ancestor of Thescelosaurus shows evidence that these animals spent at least part of their time in underground burrows. The new species contributes to a fuller understanding of life during the mid-Cretaceous -- both above and below ground.

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Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- Cannabis use during pregnancy might affect the way a child’s brain develops after birth, a new study says.Brain imaging of children exposed to cannabis in the womb has revealed patterns consistent with reductions in brain i.

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Science Daily: Pharmacology News

JULY 9, 2024

A new study reveals that the rare Desertas Petrels (Pterodroma deserta), a wide-ranging seabird in the North Atlantic, exhibit unique foraging behaviors during hurricane season. Contrary to other pelagic seabirds, these petrels do not avoid intense tropical cyclones but instead exploit the dynamic conditions for their benefit, providing new insights into the impact of cyclones on open ocean marine life.

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Drug Patent Watch

JULY 9, 2024

To find low-competition generic drug opportunities, focus on drugs with limited competition due to small patient populations, complex formulations, or […] Source

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Drugs 104

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- Two years after the U.S. Supreme Court overturned Roe v. Wade, more Americans think their state should allow a woman to get a legal abortion for any reason, a new poll finds.Just over 6 in 10 of those questioned say women.

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Science Daily: Pharmacology News

JULY 9, 2024

A type of extinct kangaroo that lived during the Pleistocene around two and a half million to ten thousand years ago, known as the 'giant wallaby', was a poor hopper, a study has found.

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Research 97

Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- U.S. health officials have determined that untreated water used by a Florida cucumber grower is one likely source of salmonella poisoning that sickened nearly 450 people this spring.Still, that grower didn't supply all the.

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Science Daily: Pharmacology News

JULY 9, 2024

Researchers were involved in the development of a switch, an essential device in telecommunications, capable of operating at very high frequency with lower power consumption than conventional technologies. The technology has applications in the new 6G mass communication systems and is more sustainable in terms of energy consumption than current devices.

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Research 95

Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- Expectant mothers who get vaccinated to protect their newborns against respiratory syncytial virus (RSV) are not putting themselves or their babies at risk, new research affirms. It found that getting the shot during late.

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Vaccine Virus Research 96

Science Daily: Pharmacology News

JULY 9, 2024

The ability to recognize and respond to emotionally-charged situations is essential to a species' evolutionary success. A new study advances our understanding of how the brain responds to emotionally charged objects and scenes.

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Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- New research offers what could become a surprising way to diagnose whether a child has autism: Simply check the makeup of their gut microbiome.In a study published July 8 in the journal Nature Microbiology, scientists.

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Research 94

Drug Patent Watch

JULY 9, 2024

In a seismic shift for European intellectual property, the Unified Patent Court (UPC) is rapidly transforming how businesses approach patent […] Source

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Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- Where you live plays a vital role in how easy it is to receive care for heart problems.Nearly half of U.S. counties don’t have a practicing cardiologist, and those are places with the worst heart health, a new study s.

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Science Daily: Pharmacology News

JULY 9, 2024

A trove of ancient plant remains excavated in Kenya helps explain the history of plant farming in equatorial eastern Africa, a region long thought to be important for early farming but where scant evidence from actual physical crops has been previously uncovered.

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Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- Expectant mothers who get vaccinated to protect their newborns against respiratory syncytial virus (RSV) are not putting themselves or their babies at risk, new research affirms.It found that getting the shot during late.

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Vaccine Virus Research 87

Drug Patent Watch

JULY 9, 2024

The introduction of biosimilars has significantly altered the landscape of biologic drug distribution models.

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Biosimilars Drugs 104

Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- A new urine test might help doctors more easily screen for cervical cancer, researchers report.The test looks for proteins generated by a type of cancer-causing human papillomavirus, HPV 16. HPV strains 16 and 18 are.

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Doctors Research 81

BioPharma Drive: Drug Pricing

JULY 9, 2024

The biotech’s stock rose more than 60% as fresh data appeared to alleviate some investor concerns about the therapy’s effectiveness and reliability.

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Therapies 67

Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- Prediabetes can be successfully fought through diet and exercise, a new study shows.People with prediabetes can reduce their long-term risk of death and illness if they use diet and exercise to delay the onset of diabetes.

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Drug Patent Watch

JULY 9, 2024

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.

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Drugs Marketing 45

Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- One hospital's push to transition patients who are nearing the end of life from the emergency room to hospice care appears to be working.After the program went into effect, 54% of ER patients at Brigham and Women's Hospital.

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Hospitals 68

BioPharma Drive: Drug Pricing

JULY 9, 2024

The Series A round will help the startup bring its lead candidate, an antibody aimed at the protein iRhom2, into human testing by the end of 2024.

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Disease Drugs 64

Drugs.com

JULY 9, 2024

TUESDAY, July 9, 2024 -- If it would stave off heart disease, diabetes and colon cancer, would you swear off bacon and burgers?A new international simulation projects cutting Americans' intake of processed meat alone by 30% could head off more than.

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International Disease 67

BioPharma Drive: Drug Pricing

JULY 9, 2024

On Tuesday, regulators updated the public on their yearslong probe of PBM's business practices. The report faults PBMs for profiting at the expense of patients and independent pharmacists.

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