Mon.Mar 31, 2025

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Highly accurate blood test diagnoses Alzheimer's disease, measures extent of dementia

Science Daily: Pharmacology News

A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a new study.

Disease 317
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Cell, gene therapy makers lose a champion at FDA with exit of Peter Marks

BioPharma Drive: Drug Pricing

Marks’ resignation leaves the field without a regulator many view as “integral” to its progress over the last decade.

Therapies 313
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More Type 1 Diabetics Are Obese, Taking GLP-1 Drugs

Drugs.com

MONDAY, March 31, 2025 -- Use of cutting-edge weight-loss drugs like Ozempic and Zepbound has increased dramatically among people with type 1 diabetes, raising safety concerns among experts, a new study says.Both adults and children with type 1.

Drugs 277
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New study links lower proportions of certain sleep stages to brain changes associated with Alzheimer's disease

Science Daily: Pharmacology News

New research reveals that lower proportions of specific sleep stages are associated with reduced brain volume in regions vulnerable to the development of Alzheimer's disease over time.

Disease 264
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Top FDA Vaccine Official Quits, Warns of Vaccine Misinformation

Drugs.com

MONDAY, March 31, 2025 -- A top vaccine official at the U.S. Food and Drug Administration (FDA) is stepping down, warning that vaccine misinformation is coloring the countrys top health decisions.Dr. Peter Marks, director of the FDAs Center for Bi.

Vaccine 275

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New Drug May Cut Sudden Heart Risk by 94%

Drugs.com

MONDAY, March 31, 2025 -- A new drug may help protect millions of people from heart attacks and strokes by lowering a little-known risk factor in the blood.The drug, made by Eli Lilly and called lepodisiran, lowered levels of a tiny particle called.

Drugs 262
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How discoverable, comparable and explorable is your data?

BioPharma Drive: Drug Pricing

Accelerate biomarker research with high-quality, expert-curated data to drive precision medicine.

Research 246
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Discovery of Quina technology challenges view of ancient human development in East Asia

Science Daily: Pharmacology News

Researchers have uncovered a complete Quina technological system in the Longtan site in southwest China. The discovery challenges the widely held perception that the Middle Paleolithic period was mostly static in East Asia.

Research 245
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Breasts Can Shrink Following Cancer Surgery, Radiation

Drugs.com

MONDAY, March 31, 2025 -- Breast-conserving therapy for breast cancer might not conserve as much as previously thought, a new study suggests.Womens breasts can shrink considerably after theyve undergone radiation therapy and lumpectomy for their e.

Therapies 219
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New warnings of a 'Butterfly Effect' -- in reverse

Science Daily: Pharmacology News

A new study warns that global climate change may have a devastating effect on butterflies, turning their species-rich, mountain habitats from refuges into traps. Think of it as the 'butterfly effect' -- the idea that something as small as the flapping of a butterfly's wings can eventually lead to a major event such as a hurricane -- in reverse. The new study also suggests that a lack of comprehensive global data about insects may leave conservationists and policymakers ill-prepared to mitigate b

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Bad Sleep Linked To Alzheimer's-Related Brain Changes

Drugs.com

MONDAY, March 31, 2025 -- Certain stages of sleep deep sleep and dream sleep appear to contribute to brain health in ways that affect risk of Alzheimers disease, a new study says.People who get less deep sleep or dream sleep have smaller volum.

Disease 214
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'She loves me, she loves me not': Physical forces encouraged evolution of multicellular life, scientists propose

Science Daily: Pharmacology News

A study presents a striking example of cooperative organization among cells as a potential force in the evolution of multicellular life. The study is based on the fluid dynamics of cooperative feeding by Stentor, a relatively giant unicellular organism.

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Surgery Not Necessary In Some Early-Stage Breast Cancers, Study Says

Drugs.com

MONDAY, March 31, 2025 -- Surgery might not be needed to treat as many as 60% of early-stage breast cancers, a new study says.Breast cancers that have been completely wiped out by chemotherapy and radiation treatment are not likely to come back.

Treatment 162
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Martian dust could pose health risks to future astronauts

Science Daily: Pharmacology News

Inhaling dust particles from the Red Planet over long periods of time could put humans at risk of developing respiratory issues, thyroid disease and other health problems.

Disease 171
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FDA Approves Cabozantinib for Previously Treated Advanced Neuroendocrine Tumors

Drugs.com

MONDAY, March 31, 2025 -- The U.S. Food and Drug Administration has approved cabozantinib (Cabometyx), an oral tyrosine kinase inhibitor, for patients with previously treated advanced neuroendocrine tumors, offering a new standard of care for this.

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Thinner Arctic sea ice may affect global ocean circulation

Science Daily: Pharmacology News

One of the ocean currents in the Arctic Ocean is at risk of disappearing this century because of climate change, according to a new study. As a result, the North Atlantic could be flooded with freshwater which would weaken the global ocean circulation.

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Local Outbreaks Can Motivate The Vaccine-Hesitant, Poll Finds

Drugs.com

MONDAY, March 31, 2025 -- COVID-19 and influenza burned through the U.S. during this years cold and flu season, and deadly measles outbreaks have sickened people in 19 states.So what does it take to get people vaccinated against these preventable d.

Vaccine 147
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Isomorphic raises $600M on big ambitions for AI drugmaking tech

BioPharma Drive: Drug Pricing

The drug discovery company, which has partnerships with Eli Lilly and Novartis, is developing AI models to design drugs and predict molecular structures.

Drugs 141
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Smartwatches Can Help People Control Diabetes Through Exercise

Drugs.com

MONDAY, March 31, 2025 -- Wearing a smartwatch might do more than track steps (or your texts) -- it could be a powerful tool for helping people with type 2 diabetes stay active, a new study says.Participants were more likely to start and maintain.

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Lilly study data reinforce potential of new kind of heart drug

BioPharma Drive: Drug Pricing

Drugs from Novartis, Amgen and now Lilly have proven powerfully effective at reducing Lp(a). Whether that will translate to a cardioprotective benefit won’t be answered until Phase 3 tests read out.

Drugs 141
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Ground Coffee Recalled in 15 States for Caffeine Labeling Error

Drugs.com

MONDAY, March 31, 2025 -- The U.S. Food and Drug Administration (FDA) has recalled ground coffee sold in 15 states after finding it may have been wrongly labeled as decaffeinated.Hundreds of 12-ounce bags of Our Family Traverse City Cherry Decaf.

FDA 130
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Project Optimus: Transforming Dose Optimization in Oncology Drug Development

Fierce BioTech

| Project Optimus is changing the landscape of oncology drug development by redefining dose optimization standards. Learn how sponsors can align with FDA expectations and implement more precise dose-finding strategies. Watch the full interview with Alex MacDonald now!

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Aarti Krishnan

Broad Institute

James J. Collins Research Group at MIT - The Collins lab focuses on synthetic biology and systems biology, with an emphasis on infectious diseases and antibiotic resistance.

Disease 52
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Five critical challenges awaiting Marty Makary

Agency IQ

By Alexander Gaffney, MS, RAC MARTY MAKARY has been confirmed by the Senate as the next commissioner of the FDA. But Makary will almost immediately face challenges that will make his tenure as commissioner especially difficult. Here, AgencyIQ identifies and explores five of the biggest hurdles the new commissioner will face. Fill out the form to read the full article.

FDA 52
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Navigating the Transition from ICH E6 (R2) to (R3)

thought leadership

Ensuring Compliance with ProPharma's Expert Support The global regulatory landscape for clinical trials continues to evolve to keep pace with technological advancements, risk management, and the increasing complexity of clinical research.

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Yu Zhang

Broad Institute

James J. Collins Research Group at MIT - The Collins lab focuses on synthetic biology and systems biology, with an emphasis on infectious diseases and antibiotic resistance.

Disease 40