Drug Discovery World

SEPTEMBER 9, 2024

Dr Mutlu Dogruel, Vice President of AI Solutions at Cresset, examines AI’s transformative potential, highlights the current challenges and introduces a series of potential solutions to implement AI in the drug discovery landscape successfully. The use of artificial intelligence (AI) is creating a paradigm shift in drug discovery and optimisation processes, allowing for the analysis of large-scale datasets, the design of new molecules, and the prediction of drug properties more efficiently.

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Drugs Bioinformatics Computational Chemistry International 162

Science Daily: Pharmacology News

SEPTEMBER 9, 2024

Scientists have developed a new AI algorithm that can separate brain patterns related to a particular behavior. This work promises to improve brain-computer interfaces and aid with the discovery of new brain patterns.

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Drug Discovery World

SEPTEMBER 9, 2024

NRG Therapeutics has been awarded a non-dilutive grant from Target ALS Foundation to support its discovery programme for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease or motor neurone disease. It is one of five recipients of the 2024 In Vivo Target Validation grants in collaboration with Biospective. The In Vivo Target Validation Program aims to generate high-quality data on candidate therapeutics in animal models of ALS, to provide access to in-kind funding for a resou

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Small Molecule Clinical Trials Disease Trials 162

Science Daily: Pharmacology News

SEPTEMBER 9, 2024

Researchers have developed a robotic leg with artificial muscles. Inspired by living creatures, it jumps across different terrains in an agile and energy-efficient manner.

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Research 136

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

SEPTEMBER 9, 2024

The tenth eBook of the Hamilton series is now available to download, entitled ‘ Cell-Based High-Throughput Screening ‘ The eBook covers: Cell-based models used in research – pros and cons. Challenges of cell-based high-throughput screening. Hamilton software and hardware tools for cell-based assays. Download now. The post eBook: Overcome the challenges of cell-based high-throughput screening appeared first on Drug Discovery World (DDW).

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Cell Based Assays Research Drugs 147

Science Daily: Pharmacology News

SEPTEMBER 9, 2024

Out-of-body experiences, such as near-death experiences, can have a 'transformative' effect on people's ability to experience empathy and connect with others, new research explains.

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Research 130

Drugs.com

SEPTEMBER 9, 2024

MONDAY, Sept. 9, 2024 -- A slow-release form of semaglutide could allow people who use Wegovy or Ozempic to get shots once a month, instead of the weekly injections they now take, a new study demonstrates.The new formulation encases semaglutide in.

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Drug Discovery World

SEPTEMBER 9, 2024

In the tenth eBook of the Hamilton series, ‘Cell-Based High-Throughput Screening’, we discuss: Cell-based models used in research – pros and cons. Challenges of cell-based high-throughput screening. Hamilton software and hardware tools for cell-based assays. The post Cell-Based High-Throughput Screening appeared first on Drug Discovery World (DDW).

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Cell Based Assays Research Drugs 130

Science Daily: Pharmacology News

SEPTEMBER 9, 2024

The study shows how global warming can combine with normal variations in the weather to produce decade-long periods of very rapid changes in both extreme temperatures and rainfall.

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Drugs.com

SEPTEMBER 9, 2024

MONDAY, Sept. 9, 2024 -- Diabetics who fly with an insulin pump could find themselves with lower-than-normal blood sugar levels, a new study says.Altitude appears to affect the ability of insulin pumps to deliver a steady supply of the hormone.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Perficient: Drug Development

SEPTEMBER 9, 2024

Sitecore Content Hub is a world-class platform for centralizing and managing content across various channels. It helps businesses organize and streamline often chaotic, messy content operations. It does this by providing an architecture or schema for content and its interconnections. A schema defines how different types of assets are structured, organized, related to each other.

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Science Daily: Pharmacology News

SEPTEMBER 9, 2024

During the Age of Sail, sailors riding the trade winds past the equator dreaded becoming stranded in the doldrums, a meteorologically distinct region in the deep tropics. For at least a century, scientists have thought that the doldrums' lack of wind was caused by converging and rising air masses. Now, new research suggests that the opposite may be true.

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Research 119

Drugs.com

SEPTEMBER 9, 2024

MONDAY, Sept. 9, 2024 -- Folks who like to stay up late are nearly 50% more likely to develop type 2 diabetes than those who go to bed earlier, a new study finds.However, it’s not just because they have an unhealthy lifestyle, according to findings.

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Science Daily: Pharmacology News

SEPTEMBER 9, 2024

In a new study, astronomers report novel evidence regarding the limits of planet formation, finding that after a certain point, planets larger than Earth have difficulty forming near low-metallicity stars.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

SEPTEMBER 9, 2024

MONDAY, Sept. 9, 2024 -- The time is now to prepare for a potential pandemic involving the H5N1 bird flu, says a group of international vaccine and public health experts.Avian influenza vaccines need to developed, stockpiled and even delivered to.

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Science Daily: Pharmacology News

SEPTEMBER 9, 2024

Researchers published findings describing a new species of fanged frog, named Limnonectes cassiopeia, from the Philippine island of Luzon.

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Research 108

Drugs.com

SEPTEMBER 9, 2024

MONDAY, Sept. 9, 2024 -- In exercise bike tests, twentysomethings who'd been vaping for at least two years had much lower exercise capacity than those who didn't, and the losses were equal to those of folks who'd spent a similar amount of time.

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BioPharma Drive: Drug Pricing

SEPTEMBER 9, 2024

A once-daily pill the biotech is developing helped some people with obesity lose more than 5% of their weight in a month, spurring a stock bump and plans to bring the drug into further testing.

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Drugs 70

Drugs.com

SEPTEMBER 9, 2024

Key TakeawaysA man who received the world’s first combined whole-eye and partial face transplant is doing wellHis body has not rejected either his new face of his new left eyeHowever, vision has not returned in the donated eyeMONDAY, Sept. 9, 2024 -.

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BioPharma Drive: Drug Pricing

SEPTEMBER 9, 2024

The startup believes T cell engagers, rather than cell therapies, will prove the “right horse to bet on” in the race to develop new inflammatory disease treatments, its CEO said.

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Drugs.com

SEPTEMBER 9, 2024

MONDAY, Sept. 9, 2024 -- At least 65 people in nine states have been sickened in a salmonella outbreak linked to recalled eggs, U.S. health officials report."The nine states include the three states where the eggs were sold -- Illinois, Michigan.

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New Drug Approvals

SEPTEMBER 9, 2024

Arbemnifosbuvir, AT-752, 1998705-63-7, PD160572 E9V7VHK36U INN 12706 C 24 H 33 FN 7 O 7 P 581.5 g/mol SYN propan-2-yl (2 S )-2-[[[(2 R ,3 R ,4 R ,5 R )-5-[2-amino-6-(methylamino)purin-9-yl]-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate L-ALANINE, N-((P(R),2’R)-2-AMINO-2′-DEOXY-2′-FLUORO-N,2′-DIMETHYL-P-PHENYL-5′ -ADENYLYL)-, 1-METHYLETHYL ESTER N-((P(R),2’R)-2-AMINO-2′-DEOXY-2′-FLUORO-N,2′-DIMETHYL-P-PHENYL

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Production Pharmaceuticals 62

NIOSH Science Blog: Drugs

SEPTEMBER 9, 2024

Artificial intelligence (AI)—the field of computer science that designs machines to perform tasks that typically require human intelligence—has seen rapid advances leading to cutting‐edge innovations in language, vision, reasoning, and human‐machine collaboration across industries, economies, and labor markets.[1] [2] In the workplace, the adoption of AI technologies can result in a broad range of hazards and risks to workers, as illustrated by the recent growth in industrial robotics and algori

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New Drug Approvals

SEPTEMBER 9, 2024

Zelicapavir, Enanta Pharmaceuticals Alternative Names: EDP-938; EP 023938 cas 2070852-76-3 RSV-IN-7 549.5 g/mol, C 27 H 22 F 3 N 7 O 3 UNII U4OI721DMD (3 S )-3-[[5-[3-morpholin-4-yl-5-(trifluoromethyl)pyridin-2-yl]-1,3,4-oxadiazol-2-yl]amino]-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one SYN New England Journal of Medicine (2022), 386(7), 655-666 WO2022157327 WO2018152413 WO2019067864 WO2017015449 PATENT WO2018152413 [link] Step 5 : ( < S f )-3-((5-(3-morpholino-5-(trifluoromethyl)pyridin-2-y

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Pharmaceuticals 62

BioPharma Drive: Drug Pricing

SEPTEMBER 9, 2024

Results from a small study suggest Relay's drug could avoid some of the toxicity associated with existing PI3Ka inhibitors like Novartis' Piqray.

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Trials Drugs 70

Drug Patent Watch

SEPTEMBER 9, 2024

The contract development and manufacturing organization (CDMO) industry is poised to continue its rapid growth and evolution over the next decade. As biopharma companies increasingly rely on CDMOs to develop and manufacture complex therapeutics, several key trends are shaping the future of the industry.

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Reprocell

SEPTEMBER 9, 2024

In India, breast cancer is the leading cause of cancer-related deaths among women, with an alarming rise in cases over the past two decades. Understanding the genetic factors influencing breast cancer is crucial for early diagnosis and effective treatment. Recent findings from a study conducted at a diagnostic lab in India shed light on the prevalence of BRCA gene mutations in Indian breast cancer patients.

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Treatment 59

BioPharma Drive: Drug Pricing

SEPTEMBER 9, 2024

The escalating global challenge of Alzheimer's Disease (AD) demands new approaches to detection, diagnosis and treatment.

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Therapies Treatment Disease 70

Perficient: Drug Development

SEPTEMBER 9, 2024

Oracle routinely announces significant future changes for EPM customers in each month’s cloud readiness documentation. If you’re not aware, Oracle EPM cloud updates are published monthly. If you read the details within the ‘Important Actions and Considerations’ section (located at the bottom of each readiness release), you will notice several very interesting announcements that we’ve highlighted below.

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Fierce BioTech

SEPTEMBER 9, 2024

When Health Stakeholders Collaborate Better, Patients Win When different healthcare stakeholders have goals that align, patients can stand to benefit. Access this resource today to discover what life sciences organizations can do to help get critical conversations started. This valuable guide will help in developing a roadmap for better, more productive healthcare stakeholder partnerships that can improve patient health and close gaps in care. tharilall Mon, 09/09/2024 - 16:46 When different hea

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Drugs.com

SEPTEMBER 9, 2024

MONDAY, Sept. 9 , 2024 -- Catherine, Princess of Wales, has announced that she has completed chemotherapy for an unnamed form of cancer.The princess, 42, made the announcement in a video message posted by Kensington Palace on Monday. She said she.

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Perficient: Drug Development

SEPTEMBER 9, 2024

For more than a decade, Salesforce CEO Marc Benioff has championed the concept of shoshin —a “beginner’s mind” that allows for continuous innovation and reinvention. As the company now embarks on its “hard pivot” to Agentforce , this philosophy takes on new relevance. Agentforce isn’t just an extension of Salesforce’s AI capabilities—it’s a reimagining of what AI can do for business.

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Compliance Marketing Production 52

Drugs.com

SEPTEMBER 9, 2024

MONDAY, Sept. 9, 2024 -- A new survey finds the majority of American men believe the first step in prostate cancer screening is an invasive rectal exam by their doctor.That's not true, but mistaken beliefs like these could keep men from getting.

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Perficient: Drug Development

SEPTEMBER 9, 2024

In today’s fast-paced world, company culture has become a keystone of a successful organization. It’s not just about the perks or the office decor; it’s about creating an environment where employees feel valued, connected, and motivated. Lisa Mudge- Talent Acquisition Specialist and Katie Burwell- Sr. Talent Acquisition Specialist have partnered to highlight why company culture is so important.

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