Drug Discovery World

OCTOBER 9, 2023

Positive Phase I trial data indicates that Reqorsa (quaratusugene ozeplasmid) has shown early efficacy for the treatment of non-small cell lung cancer (NSCLC). The data will be presented at the 2023 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston. Developed by gene therapy company Genprex, Reqorsa is a non-viral gene therapy that leads to expression of the TUSC2 tumour suppressor gene in cancers.

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Therapies Clinical Trials Trials International 278

Drug Patent Watch

OCTOBER 9, 2023

The article titled “Reviving an R&D Pipeline: A Step Change in the Phase II Success Rate” discusses Pfizer’s efforts to improve its research and development (R&D) productivity. The pharmaceutical industry… The post Reviving an R&D Pipeline appeared first on DrugPatentWatch - Make Better Decisions.

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Pharmaceuticals Production Research 114

Drug Discovery World

OCTOBER 9, 2023

According to the National Institutes for Health, some form of long Covid affects around 10% of people infected with Covid-19, with fatigue being the most common symptom. Despite the size of the market and the global impact, there are currently no effective treatments. Diana Spencer caught up with Bill Hinshaw, President & CEO of Axcella Therapeutics, to find out why.

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Drug Development Clinical Trials Virus Molecular Biology 148

Fierce BioTech

OCTOBER 9, 2023

AnaptysBio announces top-line data showing rapid clearance of generalized pustular psoriasis (GPP), a rare systemic skin disease jpiatt Mon, 10/09/2023 - 12:17

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Disease 114

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

OCTOBER 9, 2023

Hosted by DDW and co-sponsored by Benchling and Proscia, “AI and Lab Automation: What are the key benefits and latest innovations?” will be free to attend on 10 October at 7AM PDT / 10AM EST / 3PM BST / 4PM CET. Join this free webinar to learn about the key benefits and latest innovations to be aware of in AI and lab automation. In his presentation, Jeremy Skillington will speak about how Poolbeg Pharma has yielded significant breakthroughs in its AI-led programmes targeting influenza and RSV us

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Trials Production Drugs Marketing 130

Science Daily: Pharmacology News

OCTOBER 9, 2023

If global temperatures increase by 1 degree Celsius (C) or more than current levels, each year billions of people will be exposed to heat and humidity so extreme they will be unable to naturally cool themselves, according to interdisciplinary research. Results indicated that warming of the planet beyond 1.5 C above preindustrial levels will be increasingly devastating for human health across the planet.

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Research 107

BioPharma Drive: Drug Pricing

OCTOBER 9, 2023

The purchase agreement with Chongqing Zhifei Biological Products is part of GSK’s plan to double sales of the shingles vaccine by 2026.

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Vaccine Production 112

PPD

OCTOBER 9, 2023

“Patient-centric” is used frequently to describe today’s clinical trial and health care landscape. The industry applauds that point of view and strives to include a patient-centric approach in all aspects of clinical trial designs. However, when it comes to supporting complex trials with multiple participation barriers, there is a need to go beyond what the industry envisions to increase centricity through patient concierge services and hear feedback directly from patients.

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Clinical Trials Trials Compliance International 98

Science Daily: Pharmacology News

OCTOBER 9, 2023

Scientists have developed new tools, based on AI language models, that can characterize subtle signatures in the speech of patients diagnosed with schizophrenia.

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BioPharma Drive: Drug Pricing

OCTOBER 9, 2023

The agency rejected Alnylam’s application for approval of its medicine patisiran in people with a rare heart condition, setting back the company’s plans.

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RNA FDA Drugs 67

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Clinical Trials

Science Daily: Pharmacology News

OCTOBER 9, 2023

An international team of scientists have discovered a huge spike in radiocarbon levels 14,300 years ago by analyzing ancient tree-rings found in the French Alps. The radiocarbon spike was caused by a massive solar storm, the biggest ever identified. A similar solar storm today would be catastrophic for modern technological society – potentially wiping out telecommunications and satellite systems, causing massive electricity grid blackouts, and costing us billions.

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Research International 90

Drug Patent Watch

OCTOBER 9, 2023

For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.com The post New tentative approval for Mylan Gmbh drug trastuzumab-dkst appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Pharmaceuticals 59

Science Daily: Pharmacology News

OCTOBER 9, 2023

Geologists have reconstructed a massive and previously unknown tectonic plate that was once one-quarter the size of the Pacific Ocean. The team had predicted its existence over 10 years ago based on fragments of old tectonic plates found deep in the Earth’s mantle. To the lead researchers surprise, she found that oceanic remnants on northern Borneo must have belonged to the long-suspected plate, which scientists have named Pontus.

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Research 88

Perficient: Drug Development

OCTOBER 9, 2023

Image Role in Tableau: The first rule that we are going to discuss is the geographic role. If you have in your data field that contains location information or Geographical areas, then you can assign it to a geographical role in tableau. Based on the type of the location such as City, Country, State, Postal Code. Assigning this extra role can help tableau to plot your data correctly if you are showing Data in map visualization in tableau there are multiple geographic roles as mentioned below bu

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

OCTOBER 9, 2023

The Gulf Stream is intrinsic to the global climate system, bringing warm waters from the Caribbean up the East Coast of the United States. As it flows along the coast and then across the Atlantic Ocean, this powerful ocean current influences weather patterns and storms, and it carries heat from the tropics to higher latitudes as part of the Atlantic Meridional Overturning Circulation.

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Fierce BioTech

OCTOBER 9, 2023

Market-Moving Healthcare Trends to Watch in Q4 dwunderlin Mon, 10/09/2023 - 15:02 Tue, 11/14/2023 - 11:00 Resource Type Webinar Sara Mallatt Stahl Promotion Start Mon, 10/16/2023 - 15:15 Promotion End Tue, 04/16/2024 - 15:15 Duration 60 Minutes As we approach 2024, the healthcare and life sciences sectors are undergoing significant transformations, particularly in biopharma and MedTech.

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Marketing Science Treatment Disease 52

Science Daily: Pharmacology News

OCTOBER 9, 2023

New analysis of the remains of victims of the 1918 influenza pandemic, which killed an estimated 50 million people worldwide, contradicts the widespread belief the flu disproportionately impacted healthy young adults.

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SCIENMAG: Medicine & Health

OCTOBER 9, 2023

A team of researchers from Queen Mary University of London and the University of Campinas in Brazil has found that tropical forest ecosystems are more reliant on aquatic insects than temperate forest ecosystems and are therefore more vulnerable to disruptions to the links between land and water.

Research 52

Research 52

Fierce BioTech

OCTOBER 9, 2023

Real-World Solutions for Life Sciences: Harnessing the Power of Innovative Technologies to Stay Competitive in a Dynamic Market Join us for a firsthand look at these real-world applications of technology in the life sciences industry. Gain valuable insights and inspiration to embark on your own transformative journey toward business success. Register now. lpastoria Mon, 10/09/2023 - 09:14 Join us for a firsthand look at these real-world applications of technology in the life sciences industry.

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Science Marketing 52

SCIENMAG: Medicine & Health

OCTOBER 9, 2023

Miriam Merad, M.D., Ph.D., an esteemed immunologist at the Icahn School of Medicine at Mount Sinai, has been elected to the National Academy of Medicine (NAM) in recognition of her pioneering contributions to the fields of immunology and cell biology. Credit: Lab of Miriam Merad, MD, PhD Miriam Merad, M.D., Ph.D.

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Cell Biology 52

Perficient: Drug Development

OCTOBER 9, 2023

Why aren’t we helping your company accelerate your business outcomes? At the size of over 7,500 teammates throughout the globe, the sun never sets on Perficient. We consistently deliver results onshore, near shore, and offshore for 7 out of the top 10 global OEMs, and we have long term partnerships with 95% repeat business rates that demonstrate our proven success record with our clients.

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Research Marketing 52

SCIENMAG: Medicine & Health

OCTOBER 9, 2023

LOS ANGELES — Approximately 7% of Americans have had long COVID, a range of ongoing health problems experienced after infection and recovery from COVID-19. Symptoms can include fatigue, brain fog, headaches, chest pain, heart palpitations and more.

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Perficient: Drug Development

OCTOBER 9, 2023

Ever felt a twinge of confusion when faced with the decision of whether to use a mixin or extend in SCSS? You’re not alone. Today, we’re going on a journey together, where you’ll discover the complexity of mixins and extends, and by the end, you’ll know exactly when to employ each one. Let’s dive in, shall we? Mixins in SCSS: Have You Met Them?

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SCIENMAG: Medicine & Health

OCTOBER 9, 2023

Researchers from the United States, Brazil, and Spain, including scientists with the Fralin Biomedical Research Institute at VTC, published an analysis in a special edition of the British Medical Journal with a timely and controversial recommendation: It’s time for an international shift in the way we think about ultra-processed food.

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International Research 52

Perficient: Drug Development

OCTOBER 9, 2023

With the introduction of Adobe Experience Manager as a Cloud Service (AEMaaCS), customers who currently run AEM on premise or through Adobe Managed Services (AMS) and want to migrate to the cloud need to plan for changes made to the AEM repository. One tool to assist in the process is the Repository Modernizer. This tool comes after you’ve already used the Best Practices Analyzer and is a part of the code refactoring process.

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Packaging 52

SCIENMAG: Medicine & Health

OCTOBER 9, 2023

Peer-reviewed / Modelling, Review, and Opinion / People Credit: The Lancet Peer-reviewed / Modelling, Review, and Opinion / People New World Stroke Organization-Lancet Neurology Commission forecasts future epidemiological and economic impacts of stroke, identifies evidence-based recommendations for improving the four pillars namely: surveillance, prevention, treatment and rehabilitation.

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Treatment 52

sptlabtech

OCTOBER 9, 2023

Learn how automated liquid handling increases throughput in NGS-based LDTs and how to choose a scalable and reliable system that works for your clinical lab

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Laboratories 52

BioPharma Drive: Drug Pricing

OCTOBER 9, 2023

Oncology manufacturers can improve access by using claims, labs, pathway and policy data to address misalignment.

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Therapies 62

SCIENMAG: Medicine & Health

OCTOBER 9, 2023

Models built on machine learning in health care can be victims of their own success, according to researchers at the Icahn School of Medicine and the University of Michigan. Their study assessed the impact of implementing predictive models on the subsequent performance of those and other models.

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Research 40

Drug Patent Watch

OCTOBER 9, 2023

This chart shows the pharmaceutical companies with the most patents in Mexico. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical companies have the most drug patents in Mexico? appeared first on DrugPatentWatch - Make Better Decisions.

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Pharmaceutical Companies Pharmaceuticals Drugs 105

Drug Discovery World

OCTOBER 9, 2023

Join DDW for this exclusive free event, Scaling up in vitro transcription: Key results and considerations , which is supported by Thermo Fisher Scientific. In vitro transcription (IVT) can be a complicated reaction. Scaling up this process requires a good understanding of the various reaction parameters that need to be optimised and controlled to give the best result in terms of mRNA yields and quality.

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DNA Production Marketing Drugs 130

Drug Target Review

OCTOBER 9, 2023

When the zygote, or fertilized egg, begins its developmental journey, the inner cell mass that will eventually give rise to the individual retains its remarkable pluripotent stem cell potential during the initial weeks. In simpler terms, each cell within this cluster possesses the capacity to form an entire new individual and all the diverse cell types essential for the human body.

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Doctors Therapies Disease Research 110

FDA Law Blog: Biosimilars

OCTOBER 9, 2023

By Faraz Siddiqui & Sophia R. Gaulkin & Jeffrey N. Wasserstein — The U.S. District Court for the District of Columbia has vacated the Notice of Benefits and Payment Parameters (NBPP) rule issued in May 2020 (2020 NBPP Rule) which allowed health insurers and pharmacy benefit managers to use copay accumulators to exclude drug manufacturers’ copay assistance when calculating patients’ out-of-pocket costs and cost-sharing ceilings under the Affordable Care Act (ACA).

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Pharmacy Regulations Drugs 40

Drug & Device Law

OCTOBER 9, 2023

We’ve discussed our Drug and Device Law Blog elder care duties before and how it has educated us about health issues faced by the senior population. Shingles is one health risk that increases as you get older. It is often described as a painful rash, but “painful rash” doesn’t really capture how bad shingles can be. “Intense burning sensation” with pain that “can last for months or even years after the rash goes away” is closer, but still falls short of the acute reality of the experience.

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Vaccine Testimonials Virus Production 59