Sun.Sep 22, 2024

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Is It a Cold, Flu or COVID? An Expert Helps You Sort It Out

Drugs.com

SUNDAY, Sept. 22, 2024 -- It's that time of year when respiratory viruses start to circulate widely, but how can you tell the difference between the symptoms of a cold, the flu and COVID?Dr. William Brian Glenn, from Hackensack Meridian Medical.

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Nuclear Receptors: A new mode of inhibition

Covalent Modifiers

Andrew D Huber, Taosheng Chen eLife 2024, 13 :e101446. [link] The article presents the discussion on interaction of covalent inhibitors GW9662 and T0070907 with the peroxisome proliferator-activated receptor gamma (PPARγ), revealing new insights into how these compounds influence receptor activity. Topics include the role of PPARγ in regulating fatty tissue and glucose levels; and the effects of covalent inhibitors on PPARγ's ligand-binding site and its interaction with co-activators and co-repr

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State Management in LWC: Part 2

Perficient: Drug Development

In Part 1 of this series, we explored the basics of state management in Lightning Web Components (LWC), focusing on local state management within individual components. If you haven’t read it yet, I recommend starting with Part 1 to grasp the foundational concepts. In this second part, we’ll dive into more advanced territory: shared and global state management.

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FDA Hosts Webinar for Stage 1 Requirements under LDT Final Rule

FDA Law Blog: Biosimilars

By Steven J. Gonzalez & Lisa M. Baumhardt, Senior Medical Device Regulation Expert — On August 22, 2024, FDA hosted a webinar to provide further guidance on the regulatory requirements it intends to apply to Laboratory Developed Test (LDT) developers in Stage 1 of the phaseout policy of the LDT Final Rule – during which FDA has said laboratories developing LDTs will need to comply with Medical Device Reporting (MDR) (21 CFR Part 803), Corrections and Removals (21 CFR Part 806), and Complaint

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Leveraging AI for Salesforce Security

Perficient: Drug Development

In an increasingly digital world, security is a top priority for organizations handling sensitive data, especially on platforms like Salesforce. As cyber threats become more sophisticated, traditional security measures may no longer be enough to protect against emerging risks. Enter Artificial Intelligence (AI), which offers a game-changing approach to Salesforce security by detecting anomalies, identifying potential threats, and automating responses.

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Making Eggs Without Ovaries

Codon

Today, we’re launching Issue 04 with this essay about the future of fertility and in vitro oogenesis — a technology that could soon be used to convert human skin cells into eggs or sperm — by one of its foremost developers. Thanks for reading. In March 2023, a research team at Osaka University announced an extraordinary achievement : the production of viable eggs using cells taken from male mice.

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