Chemical Biology and Drug Design

NOVEMBER 21, 2024

Edaravone significantly lowered glucose, leptin, insulin, apolipoprotein-B, body weight, weight gain, food, and water intake in rats. The intervention significantly reduced heart rate, systolic, diastolic, and mean diastolic blood pressure. The lipid profile, antioxidant levels, inflammatory cytokines, and MMP levels were also affected in atherosclerotic rats.

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Disease Research 100

Science Daily: Pharmacology News

NOVEMBER 21, 2024

A new animal study shows that males and females have profoundly different sleep patterns. The findings shed light on what may drive differences in humans and have broad implications for preclinical research that, for decades, has focused primarily on males.

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Research 117

Drugs.com

NOVEMBER 21, 2024

THURSDAY, Nov. 21, 2024 -- After a hit to the head or a fall, people, especially seniors, can develop a dangerous pooling of blood and fluid between the brain's surface and it's protective covering, the dura.These "subdural hematomas" typically.

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Science Daily: Pharmacology News

NOVEMBER 21, 2024

After severe heart failure, the ability of the heart to heal by forming new cells is very low. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart.

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Treatment 115

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Drugs.com

NOVEMBER 21, 2024

THURSDAY, Nov. 21, 2024 -- U.S. health care costs are among the world's highest, and 1 in 4 adults with health coverage struggle with high out-of-pocket costs, a new survey shows.The survey -- by the Commonwealth Fund, a health-care focused think.

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Science Daily: Pharmacology News

NOVEMBER 21, 2024

Axions are the most likely candidate for enigmatic dark matter that dominates the universe. Astrophysicists are searching for evidence of high-mass axions produced during supernovae. Scientists propose that a quick way to find these axions is to look for a gamma ray burst coincident with a neutrino burst from a nearby core collapse supernova. But we need a fleet of gamma ray telescopes to insure we capture these rare events.

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BioPharma Drive: Drug Pricing

NOVEMBER 21, 2024

Venture capital firms incubate, grow and finance dozens of new drug companies each year. Follow the money they channel into the industry with this database.

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Drugs 109

Drugs.com

NOVEMBER 21, 2024

THURSDAY, Nov. 21, 2024 -- People whose genes put them at high risk for dementia may be able to fight Mother Nature and win, new research out of Sweden suggests.The weapon: Working out on a regular basis to improve cardiorespiratory fitness, also.

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Research 95

Science Daily: Pharmacology News

NOVEMBER 21, 2024

A massive collision of galaxies sparked by one travelling at a scarcely-believable 2 million mph (3.2 million km/h) has been seen in unprecedented detail by one of Earth's most powerful telescopes. The dramatic impact was observed in Stephan's Quintet, a nearby galaxy group made up of five galaxies first sighted almost 150 years ago. It sparked an immensely powerful shock akin to a 'sonic boom from a jet fighter' -- the likes of which are among the most striking phenomena in the Universe.

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Drugs.com

NOVEMBER 21, 2024

THURSDAY, Nov. 21, 2024 -- For astronauts who spend months at a time working on the International Space Station (ISS), there's good news.While their bodies and brains are affected by radiation, altered gravity, challenging working situations and.

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International 88

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Science Daily: Pharmacology News

NOVEMBER 21, 2024

A new study estimates that a 1-meter sea level rise by 2100 would affect over 14 million people and $1 trillion worth of property along the Southeast Atlantic coast.

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Drugs.com

NOVEMBER 21, 2024

THURSDAY, Nov. 21, 2024 -- A wearable patch the size of a postage stamp that can monitor blood pressure continuously could soon help people manage their hypertension.Researchers at the University of California, San Diego, who developed the wearable.

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Science Daily: Pharmacology News

NOVEMBER 21, 2024

Compared to children, adults don't play as much, but social play into adulthood is considered a universal human trait. Play has a role in building tolerance, cohesion, bonding, and cooperation. By comparison, play in adults of other species has been considered rare, and yet a new study shows that some chimpanzees, like people, continue to play often throughout their entire lives and especially before engaging in acts that require collective cooperation.

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NIOSH Science Blog: Drugs

NOVEMBER 21, 2024

This is the second blog post in our series celebrating Native American Heritage Month. It provides a general description of the American Indian and Alaska Native (AI/AN) workforce using the NIOSH Employed Labor Force (ELF) Query System. Read the first blog post here. AI/AN workers are employed in various occupations and industries. Understanding where many AI/AN people work will help focus efforts to enhance workplace safety and health where AI/AN workers are employed.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

NOVEMBER 21, 2024

THURSDAY, Nov. 21, 2024 -- Think of it as collateral damage: Millions of Americans say they have been harmed by a loved one's drug or alcohol use.One in 3 adults who responded to a new nationwide survey said they had suffered "secondhand harm" from.

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Drugs 72

Science Daily: Pharmacology News

NOVEMBER 21, 2024

While astronomers have taken about two dozen zoomed-in images of stars in our galaxy, unveiling their properties, countless other stars dwell within other galaxies, so far away that observing even one of them in detail has been extremely challenging. Up until now.

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Drugs.com

NOVEMBER 21, 2024

THURSDAY, Nov. 21, 2024 -- A drug used to help patients lose weight and manage diabetes may also help those with heart failure, an international clinical trial shows.The test of tirzepatide, brand named Zepbound, included 731 patients with.

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Clinical Trials International Drugs Trials 89

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2024

Howard Chang will take over as chief scientific officer and senior VP of research as the biotech searches for more ways to overcome the looming loss of exclusivity for some of its top-selling medicines.

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Research 74

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

NOVEMBER 21, 2024

A new study has quantified the risk for whale-ship collisions worldwide for four geographically widespread ocean giants that are threatened by shipping: blue, fin, humpback and sperm whales. Researchers report that global shipping traffic overlaps with about 92% of these whale species' ranges. Only about 7% of areas at highest risk for whale-ship collisions have any measures in place to protect whales from this threat.

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Research 70

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2024

The startup, Pep2Tango, is combining four methods of accelerating weight loss into one medicine in the hopes of developing a treatment that can improve upon drugs like Wegovy and Zepbound.

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Drugs Treatment 74

Broad Institute

NOVEMBER 21, 2024

Researchers identify source of a brain cancer’s deadly transformation By Corie Lok November 21, 2024 Breadcrumb Home Researchers identify source of a brain cancer’s deadly transformation Slow-growing glioma tumors become more aggressive when their cells shift identities and acquire new genetic mutations. By Wynne Parry November 21, 2024 Credit: Castro Lab, Michigan Medicine, Ann Arbor Glioma tumor cells seen under a microscope Related news Targeted drug treatment leads tumor cells to imitate vir

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Research Medical Schools DNA Hospitals 69

Science Daily: Pharmacology News

NOVEMBER 21, 2024

Researchers have reported the discovery of a previously unknown compound in chloraminated drinking water. Inorganic chloramines are commonly used to disinfect drinking water to safeguard public health from diseases like cholera and typhoid fever.

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Research Disease 68

Drug Patent Watch

NOVEMBER 21, 2024

In the complex world of biopharmaceuticals, setting the right price for a new medicine is both an art and a science. It’s a decision that can make or break a product’s success, impacting everything from patient access to long-term profitability. Let’s dive into the intricacies of this crucial process and explore how companies can navigate the challenging waters of medicine launch pricing.

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Science Production 69

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2024

In buying Westlake-backed Kate Therapeutics, Novartis gets a handful of preclinical gene therapies targeting diseases like Duchenne muscular dystrophy and myotonic dystrophy type 1.

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Therapies Disease 69

Science Daily: Pharmacology News

NOVEMBER 21, 2024

Researchers have developed a groundbreaking microscopy method that enables detailed three-dimensional (3D) RNA analysis at cellular resolution in whole intact mouse brains. The new method, called TRISCO, has the potential to transform our understanding of brain function, both in normal conditions and in disease, according to the new study.

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RNA Disease Research 66

addgene Blog

NOVEMBER 21, 2024

Every few months, we highlight some of the new plasmids, antibodies, and viral preps in the repository through our Hot Plasmids articles.

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Drugs.com

NOVEMBER 21, 2024

THURSDAY, Nov. 21, 2024 -- Over 167,000 pounds of ground beef are being recalled by a Detroit meatpacker after being linked to E. coli illnesses in restaurant goers.The beef was shipped by Wolverine Packing Co. and used in restaurants nationwide.

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Perficient: Drug Development

NOVEMBER 21, 2024

Blog Objectives Understand the advantages that Pay Now provides for both your business and furthermore, your customers. Understand how Pay Now links can help reduce overdue payments. Understand how Pay Now streamlines payment processes across various channels, including Commerce, Sales, and Service. Accelerate Your Payments: Late or overdue payments can significantly affect your business operations.

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Marketing Production 52

FDA Law Blog: Biosimilars

NOVEMBER 21, 2024

By Karla L. Palmer — In a Temporary Rule announced on November 19, 2024, DEA with input from HHS again extended current telemedicine flexibilities, which were first initiated on January 31, 2020 at the inception of the COVID-19 pandemic. The federal telemedicine flexibilities (i.e., temporary exceptions from some of the requirements of the Ryan Haight Act of 2008) are extended for an additional year, until December 31, 2025.

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FDA Approval Regulations Pharmacy Licensing 52

Perficient: Drug Development

NOVEMBER 21, 2024

In this blog, we will explore how to create a custom date range picker in Vue.js that is both functional and visually appealing. We’ll also explore advanced customizations such as custom date formatting, controlling calendar visibility, and managing custom CSS classes. Benefits of Using a Custom Date Range Picker in Vue.js Creating a custom date range picker in Vue.js not only enhances the user interface but also provides users with flexibility in selecting date ranges.

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Packaging International 52

Common Sense for Drug Policy Blog

NOVEMBER 21, 2024

Alcohol-Caused Harms "Alcohol-caused harms are spread across populations and can be experienced both by people who use alcohol and by those who do not. "In the case of people who use alcohol, recent evidence indicates that, for both health and social harms, there is a risk even at low consumption levels (19–22). For example, in the European Union (EU), alcohol consumption is estimated to be the cause of 17% of the seven alcohol-related cancer types.

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Disease Research 52

Perficient: Drug Development

NOVEMBER 21, 2024

The Consumer Financial Protection Bureau (CFPB) recently issued a final rule § 1033.121(c) supporting open banking and personal financial data rights. Under this ruling, banks, credit unions, credit card issuers, and other financial service providers must enhance consumer access to personal financial data. The first compliance deadline of April 1, 2026, impacts the largest organizations.

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Common Sense for Drug Policy Blog

NOVEMBER 21, 2024

Impact of Changes in Unregulated Drug Supply on Risk of Overdose Death "The estimates presented in this article find important evidence of the potential consequences of the rapid expansion of the MA supply in Ohio, which can help inform the public health consequences of a similar expansion across the US. We find that relatively more MA detected by crime labs is either unrelated to or associated with a small, but measurable decrease in the overall risk of unintentional overdose death.

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Drugs Treatment Disease Research 52