Thu.Nov 21, 2024

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Researchers identify previously unknown compound in drinking water

Science Daily: Pharmacology News

Researchers have reported the discovery of a previously unknown compound in chloraminated drinking water. Inorganic chloramines are commonly used to disinfect drinking water to safeguard public health from diseases like cholera and typhoid fever.

Research 324
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Amgen picks prolific biotech founder Chang as new top scientist

BioPharma Drive: Drug Pricing

Howard Chang will take over as chief scientific officer and senior VP of research as the biotech searches for more ways to overcome the looming loss of exclusivity for some of its top-selling medicines.

Research 305
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3.2 million km/h galaxy smash-up

Science Daily: Pharmacology News

A massive collision of galaxies sparked by one travelling at a scarcely-believable 2 million mph (3.2 million km/h) has been seen in unprecedented detail by one of Earth's most powerful telescopes. The dramatic impact was observed in Stephan's Quintet, a nearby galaxy group made up of five galaxies first sighted almost 150 years ago. It sparked an immensely powerful shock akin to a 'sonic boom from a jet fighter' -- the likes of which are among the most striking phenomena in the Universe.

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Versant startup sets out to make a new type of obesity drug

BioPharma Drive: Drug Pricing

The startup, Pep2Tango, is combining four methods of accelerating weight loss into one medicine in the hopes of developing a treatment that can improve upon drugs like Wegovy and Zepbound.

Drugs 294
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Females sleep less, awaken more frequently than males

Science Daily: Pharmacology News

A new animal study shows that males and females have profoundly different sleep patterns. The findings shed light on what may drive differences in humans and have broad implications for preclinical research that, for decades, has focused primarily on males.

Research 302

More Trending

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The human heart may have a hidden ability to repair itself

Science Daily: Pharmacology News

After severe heart failure, the ability of the heart to heal by forming new cells is very low. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart.

Treatment 297
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There May Be a Better Way to Treat Hematoma Brain Bleeds

Drugs.com

THURSDAY, Nov. 21, 2024 -- After a hit to the head or a fall, people, especially seniors, can develop a dangerous pooling of blood and fluid between the brain's surface and it's protective covering, the dura.These "subdural hematomas" typically.

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Climate-driven hazards increases risk for millions of coastal residents, study finds

Science Daily: Pharmacology News

A new study estimates that a 1-meter sea level rise by 2100 would affect over 14 million people and $1 trillion worth of property along the Southeast Atlantic coast.

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Biotech startups are built on venture capital. Track funding rounds here.

BioPharma Drive: Drug Pricing

Venture capital firms incubate, grow and finance dozens of new drug companies each year. Follow the money they channel into the industry with this database.

Drugs 273
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Astronomers take the first close-up picture of a star outside our galaxy

Science Daily: Pharmacology News

While astronomers have taken about two dozen zoomed-in images of stars in our galaxy, unveiling their properties, countless other stars dwell within other galaxies, so far away that observing even one of them in detail has been extremely challenging. Up until now.

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1 in 4 Americans Now Struggling to Cover Medical Costs

Drugs.com

THURSDAY, Nov. 21, 2024 -- U.S. health care costs are among the world's highest, and 1 in 4 adults with health coverage struggle with high out-of-pocket costs, a new survey shows.The survey -- by the Commonwealth Fund, a health-care focused think.

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Chemists create world's thinnest 'spaghetti'

Science Daily: Pharmacology News

The world's thinnest spaghetti, about 200 times thinner than a human hair, has been created.

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Getting Fitter Can Really Help Keep Dementia at Bay

Drugs.com

THURSDAY, Nov. 21, 2024 -- People whose genes put them at high risk for dementia may be able to fight Mother Nature and win, new research out of Sweden suggests.The weapon: Working out on a regular basis to improve cardiorespiratory fitness, also.

Research 246
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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New imaging method enables detailed RNA analysis of the whole brain

Science Daily: Pharmacology News

Researchers have developed a groundbreaking microscopy method that enables detailed three-dimensional (3D) RNA analysis at cellular resolution in whole intact mouse brains. The new method, called TRISCO, has the potential to transform our understanding of brain function, both in normal conditions and in disease, according to the new study.

RNA 271
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Chronic Joint Pain Plus Depression Can Take Toll on the Brain

Drugs.com

THURSDAY, Nov. 21, 2024 -- Having achy, painful joints isn't just a physical woe: Coupled with depression, it could also degrade an older person's brain function over time.That's the conclusion of a study of almost 5,000 older Britons tracked for.

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Edaravone Ameliorate Inflammation in Vitamin D3 and High Fat Diet Induced Atherosclerosis in Rat via Alteration of Inflammatory Pathway and Gut Microbiota

Chemical Biology and Drug Design

Edaravone significantly lowered glucose, leptin, insulin, apolipoprotein-B, body weight, weight gain, food, and water intake in rats. The intervention significantly reduced heart rate, systolic, diastolic, and mean diastolic blood pressure. The lipid profile, antioxidant levels, inflammatory cytokines, and MMP levels were also affected in atherosclerotic rats.

Disease 100
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Living in Space Won't Permanently Harm Astronauts' Thinking Skills

Drugs.com

THURSDAY, Nov. 21, 2024 -- For astronauts who spend months at a time working on the International Space Station (ISS), there's good news.While their bodies and brains are affected by radiation, altered gravity, challenging working situations and.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Novartis wagers more than $1B on gene therapies for the nervous system

BioPharma Drive: Drug Pricing

In buying Westlake-backed Kate Therapeutics, Novartis gets a handful of preclinical gene therapies targeting diseases like Duchenne muscular dystrophy and myotonic dystrophy type 1.

Therapies 164
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Nearly 160 Million Americans Harmed by Another's Drinking, Drug Use

Drugs.com

THURSDAY, Nov. 21, 2024 -- Think of it as collateral damage: Millions of Americans say they have been harmed by a loved one's drug or alcohol use.One in 3 adults who responded to a new nationwide survey said they had suffered "secondhand harm" from.

Drugs 246
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Molecular Glues Discovery

Zobio

Molecular glues have emerged as an exciting new class of agents in drug discovery, offering a novel mechanism to modulate protein function, both as protein degraders and for other therapeutic targets. Unlike traditional drugs that inhibit or block protein activity, molecular glues enhance or induce new protein-protein interactions (PPIs), allowing them to activate biological pathways rather than suppressing them.

Drugs 52
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E. Coli Fears Spur Recall of 167,000 Pounds of Ground Beef

Drugs.com

THURSDAY, Nov. 21, 2024 -- Over 167,000 pounds of ground beef are being recalled by a Detroit meatpacker after being linked to E. coli illnesses in restaurant goers.The beef was shipped by Wolverine Packing Co. and used in restaurants nationwide.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Efficacy Endpoints in Oncology Clinical Trials

Quanticate

An efficacy endpoint in oncology is a characteristic or variable that measures how beneficial a treatment is to a patient’s feeling, function, and survival in a clinical trial. They are essential for assessing whether new cancer therapies are safe and efficacious [1]. Endpoints may serve different purposes, from evaluating survival rates to monitoring tumour size, as well as monitoring patient symptoms.

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Weight-Loss Drug Zepbound May Lower Heart Failure Deaths

Drugs.com

THURSDAY, Nov. 21, 2024 -- A drug used to help patients lose weight and manage diabetes may also help those with heart failure, an international clinical trial shows.The test of tirzepatide, brand named Zepbound, included 731 patients with.

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Breaking the Chains of Project Management Dysfunction

thought leadership

Right now, you are sitting in front of your computer and wondering how, based on current project status, you will achieve your remaining project goals for the year or achieve those planned for the new year.

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Kids' Injuries in Sports and at Home: When Is It Right to Seek Medical Attention?

Drugs.com

THURSDAY, Nov. 21, 2024 -- A sprain on the soccer field. A tumble to the floor at home. Kids get injured, but as a parent, when's the right time to bring them to a doctor or ER?Pediatric sports medicine and orthopedic physician Dr. Bianca Edison.

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Hot Plasmids: Fall 2024

addgene Blog

Every few months, we highlight some of the new plasmids, antibodies, and viral preps in the repository through our Hot Plasmids articles.

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