Thu.Mar 27, 2025

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HHS to cut 10,000 staff in major restructuring under RFK Jr.

BioPharma Drive: Drug Pricing

The FDA will lose about 3,500 employees under the plans, although HHS said drug, medical device and food reviewers will not be affected.

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A genetic tree as a movie: Moving beyond the still portrait of ancestry

Science Daily: Pharmacology News

Researchers have created a way to see your family tree as a movie rather than a still portrait by tracing where your ancestors moved across the globe over time. The statistical method can also be used to model disease spread and studying how animals move through geographic regions.

Disease 280
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Kansas and Ohio Report Surge in Measles Cases Amid Outbreaks

Drugs.com

THURSDAY, March 27, 2025 -- A measles outbreak in Kansas has rapidly escalated, doubling to 23 cases in less than a week, and health officials in Ohio report that a single case in Ashtabula County has spread to nine other individuals.As of last.

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Feeling the future: New wearable tech simulates realistic touch

Science Daily: Pharmacology News

Most haptic devices only deliver feedback as simple vibrations. New device applies dynamic forces in any direction to simulate a more realistic sense of touch. Small, lightweight device can enhance virtual reality, help individuals with visual impairments, provide tactile feedback for remote health visits and more.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Five Top CDC Leaders Step Down Amid Wave of Departures

Drugs.com

THURSDAY, March 27, 2025 -- The U.S. Centers for Disease Control and Prevention (CDC) is facing major changes, with five senior leaders stepping down Tuesday. These exits follow three other recent departures, meaning that as many as one-third of.

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Highly Educated Folks Face Steeper Brain Decline Following Stroke

Drugs.com

THURSDAY, March 27, 2025 -- The higher you fly, the harder you fall, the old saying goes.There might be something to that when it comes to the aftermath of a stroke, a new study suggests.People with higher education face a steeper decline in their.

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Melting ice, more rain drive Southern Ocean cooling

Science Daily: Pharmacology News

Researchers found increased meltwater and rain explain 60% of a decades-long mismatch between predicted and observed temperatures in the ocean around Antarctica.

Research 255
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Scent Test Can Sniff Out Cognitive Decline

Drugs.com

THURSDAY, March 27, 2025 -- The nose might know whether a person is showing early signs of dementia or Alzheimers disease, a new study says.Older adults whove developed mild cognitive impairment -- a precursor to dementia and Alzheimers -- score.

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Physics of irregular objects on inclined planes probed

Science Daily: Pharmacology News

How gravity causes a perfectly spherical ball to roll down an inclined plane is part of elementary school physics canon. But the world is messier than a textbook. Scientists have sought to quantitatively describe the much more complex rolling physics of real-world objects. They have now combined theory, simulations, and experiments to understand what happens when an imperfect, spherical object is placed on an inclined plane.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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NIH Ends Funding for the Effects of Climate Change on Health

Drugs.com

THURSDAY, March 27, 2025 -- The National Institutes of Health (NIH) will no longer fund new research on how climate change affects people’s health, according to records reviewed by ProPublica. The new directive was shared internally with.

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Is AI the new research scientist? Not so, according to a human-led study

Science Daily: Pharmacology News

Researchers asked generative AI to write a research paper. While adept at some steps, it wholly failed at others.

Research 177
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Collaborative Drug Discovery's Inaugural Canadian User Group Meeting

Collaborative Drug

Collaborative Drug Discovery's Inaugural Canadian User Group Meeting

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Nkarta to lay off staff, senior leadership, in bid to advance autoimmune cell therapy

BioPharma Drive: Drug Pricing

The biotech is slashing a third of its workforce and more than half of its executive team in moves it called “necessary in today’s challenging financial and competitive environment.

Therapies 164
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Mastering AWS Infrastructure as Code with Pulumi and Python

Perficient: Drug Development

Pulumi is a modern Infrastructure as Code (IaC) tool that allows you to define, deploy, and manage cloud infrastructure using general-purpose programming languages. Unlike Terraform, which uses HCL, Pulumi enables you to define infrastructure using Python, making it easier for developers to integrate infrastructure with application code. What Youll Learn How Pulumi works with AWS Setting up Pulumi with Python Deploying various AWS services with real-world examples Best practices and advanced tip

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Alcon buys majority stake in IPO-seeking cell therapy startup Aurion

BioPharma Drive: Drug Pricing

The share acquisition is the latest twist in a dispute between Alcon and fellow Aurion shareholder Deerfield Management over the direction of the company, which filed to go public in January.

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AI Improves IV Nutrition For Preemies

Drugs.com

THURSDAY, March 27, 2025 -- Artificial intelligence (AI) can help improve how premature babies are fed, giving them a better chance at normal growth and development, a new study says.Currently, preemies in a neonatal intensive care unit are fed by.

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The Benefits of Digital Transformation in Generic Drug Development

Drug Patent Watch

Revolutionizing Generic Drug Development: The Power of Digital Transformation As the pharmaceutical industry continues to evolve, one thing is clear: digital transformation is no longer a luxury, but a necessity. At the forefront of this revolution is the generic drug development sector, where innovative technologies are streamlining processes, reducing costs, and improving patient outcomes.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Obesity More Likely Among Kids Of Obese Moms, Smokers

Drugs.com

THURSDAY, March 27, 2025 -- A moms health and lifestyle choices can affect her kids risk of obesity as adults, a new study says.Specifically, a child is 3 to 4 times more likely to become an obese adult if their mom was obese, researchers rep.

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Building bridges between Denmark-based and Broad researchers

Broad Institute

Building bridges between Denmark-based and Broad researchers By Corie Lok March 27, 2025 Breadcrumb Home Building bridges between Denmark-based and Broad researchers The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease is forging connections between Danish and Broad scientists. Here are two of their stories. By Ilan Mochari March 27, 2025 Maddie Murphy (left) of the Broad and Svenja Hansson (right) of the University of Copenhagen are studying gene regulation in the Novo Nordisk F

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Heart Problems Linked To Brain Shrinkage

Drugs.com

THURSDAY, March 27, 2025 -- Heart disease might contribute to the sort of brain shrinkage seen in dementia, a new study says.People with early signs of heart problems are more likely to have brain changes associated with dementia, researchers.

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Crucial Data Solutions Launches Industry-First Subscription Model to Modernize Clinical Trial Contracting and Pricing

Crucial Data Solutions

New model empowers CROs to grow revenue, reduces costs for sponsors, and accelerates time to market RENO, NV, UNITED STATES, The post Crucial Data Solutions Launches Industry-First Subscription Model to Modernize Clinical Trial Contracting and Pricing appeared first on Crucial Data Solutions.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Chinese Woman Is Third Person To Get a Gene-Edited Pig Kidney

Drugs.com

THURSDAY, March 27, 2025 -- A Chinese woman is the third person in the world living with a gene-edited pig kidney, and nearly three weeks after surgery, doctors say shes doing well.The woman, reportedly 69 years old, had kidney failure for eight y.

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How to Use Data & Analytics to Improve Patient Recruitment Outcomes

Antidote

Recruiting the right patients for clinical trials remains a major hurdle, with nearly 80% of trials missing enrollment deadlinesdriving up costs and risking study failure.

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A lighter, smarter magnetoreceptive electronic skin

Science Daily: Pharmacology News

Imagine navigating a virtual reality with contact lenses or operating your smartphone under water: This and more could soon be a reality thanks to innovative e-skins. A research team has developed an electronic skin that detects and precisely tracks magnetic fields with a single global sensor. This artificial skin is not only light, transparent and permeable, but also mimics the interactions of real skin and the brain.

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A Novo Nordisk - Broad collaboration is connecting Denmark-based and Broad researchers

Broad Institute

A Novo Nordisk - Broad collaboration is connecting Denmark-based and Broad researchers By Corie Lok March 27, 2025 Breadcrumb Home A Novo Nordisk - Broad collaboration is connecting Denmark-based and Broad researchers The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease has built a bridge between Danish and Broad scientists. Here are two of their stories.

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Optimizing value creation in biopharma is like “the flop” in Texas hold ‘em

Plenge Gen

In a previous blog post, I argued that pharmaceutical Research and Development (R&D) is more like poker than chess given the probabilistic nature of developing new medicines. In this blog, I build out this argument further and introduce a new concept, the Critical Value Creation Period (CVCP). The CVCP is the moment in R&D where the probability of success (PoS) for an investigational medicine becoming a new medicine jumps substantially.