Nvidia Developer: Drug Discovery

NOVEMBER 13, 2024

The ability to compare the sequences of multiple related proteins is a foundational task for many life science researchers. This is often done in the form of a. The ability to compare the sequences of multiple related proteins is a foundational task for many life science researchers. This is often done in the form of a multiple sequence alignment (MSA), and the evolutionary information retrieved from these alignments can yield insights into protein structure, function, and evolutionary history.

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Science Research Drugs 135

Chemical Biology and Drug Design

NOVEMBER 13, 2024

A series of chromone derivatives were designed and synthesized. We established a NOX4 overexpression model using the NRK-49F and identified compound 14m as highly active through the assessment of intracellular ROS levels. This investigation positions 14m as a noteworthy NOX4 inhibitor, shedding light on its regulatory role in renal fibroblasts. ABSTRACT Nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) has emerged as a promising target for developing drugs to tackle renal fibrosis.

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Regulations Drugs Research 100

BioPharma Drive: Drug Pricing

NOVEMBER 13, 2024

Biotheus’ antibody drug targets PD-L1 and VEGF, a design that’s high on drugmakers’ radars after the success of Summit Therapeutics’ ivonescimab over Keytruda.

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Drugs 117

Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- The blockbuster GLP-1 drug semaglutide (Ozempic, Wegovy) could curb drinking for people battling alcohol use disorder, helping them to avoid crises that require hospitalization, new research shows. Numerous studies had.

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Hospitals Research Drugs 113

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Science Daily: Pharmacology News

NOVEMBER 13, 2024

A 'one of a kind' fossil discovery could transform our understanding of how the unique brains and intelligence of modern birds evolved, one of the most enduring mysteries of vertebrate evolution.

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Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 12, 2024 -- Overtreatment of prostate cancer is increasing in the United States among men with limited life expectancy, a new study reports.Procedures like radiation therapy and prostate surgery are being employed more often in.

Therapies 104

Therapies 104

Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- People are at higher risk of schizophrenia if they indulge in psychedelic drugs, a new study warns.Patients who land in the ER following hallucinogen use have a 21-fold higher risk of developing schizophrenia compared to.

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Drugs 90

Science Daily: Pharmacology News

NOVEMBER 13, 2024

An asteroid struck Mars 11 million years ago and sent pieces of the red planet hurtling through space. One of these chunks of Mars eventually crashed into the Earth and is one of the few meteorites that can be traced directly to Mars. This meteorite was rediscovered in a drawer at Purdue University in 1931 and therefore named the Lafayette Meteorite.

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Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- Obesity, alcohol use and other factors are driving up rates of fatty liver disease among American adults, new research warns.By 2018, federal data showed that 42% of adults had some form of fatty liver disease -- higher.

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Disease Research 88

Science Daily: Pharmacology News

NOVEMBER 13, 2024

Astronomers have identified three ultra-massive galaxies -- nearly as massive as the Milky Way -- already in place within the first billion years after the Big Bang. This surprising discovery was made possible by the James Webb Space Telescope's FRESCO program, which uses the NIRCam/grism spectrograph to measure accurate distances and stellar masses of galaxies.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- Therapy provided via telehealth can reduce a person’s risk of suicide, a new study reports.Cognitive behavior therapy reduces suicide attempts and suicidal thoughts even if delivered for a short time via telehealth, a.

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Therapies 81

Science Daily: Pharmacology News

NOVEMBER 13, 2024

Scientists using observations from NASA's Neil Gehrels Swift Observatory have discovered, for the first time, the signal from a pair of monster black holes disrupting a cloud of gas in the center of a galaxy.

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Drug Channels

NOVEMBER 13, 2024

Uh oh. As I predicted, the stand-alone Medicare Part D prescription drug plans (PDP) market is vanishing. For 2025, DCI’s exclusive analysis of Center for Medicare & Medicaid Services’ (CMS) data reveals that the number of PDPs will drop to a historic low. What’s more, the share of plans with a preferred cost sharing pharmacy network will fall to its lowest rate in more than 10 years.

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Pharmacy Marketing Drugs 78

Science Daily: Pharmacology News

NOVEMBER 13, 2024

Researchers have developed an AI powered model that -- in 10 seconds -- can determine during surgery if any part of a cancerous brain tumor that could be removed remains.The technology, called FastGlioma, outperformed conventional methods for identifying what remains of a tumor by a wide margin. Researchers say it has the potential to change the field of neurosurgery by immediately improving comprehensive management of patients with diffuse gliomas.

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Research 83

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- Most parents haven’t considered the potential risk of an unlocked, poorly stored firearm in a house their child is visiting, a new study shows.More than 60% of Illinois parents have never asked another parent about an u.

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Science Daily: Pharmacology News

NOVEMBER 13, 2024

A collection of perforated pebbles from an archaeological site in Israel may be spindle whorls, representing a key milestone in the development of rotational tools including wheels, according to a new study.

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Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- Amid an ongoing outbreak of bird flu in American dairy herds and poultry flocks, Canadian officials have announced that a teen in British Columbia has been hospitalized in critical condition with what is believed to be.

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Hospitals 75

Science Daily: Pharmacology News

NOVEMBER 13, 2024

Could social bonds be the key to human big brains? A study of the fossil teeth of early Homo from Georgia dating back 1.77 million years reveals a prolonged childhood despite a small brain and an adulthood comparable to that of the great apes. This discovery suggests that an extended childhood, combined with cultural transmission in three-generation social groups, may have triggered the evolution of a large brain like that of modern humans, rather than the reverse.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

BioPharma Drive: Drug Pricing

NOVEMBER 13, 2024

An analyst note raising questions about Amgen’s MariTide triggered a stock sell-off Tuesday. Elsewhere, Roche and Novartis struck drug discovery deals.

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Drugs 70

Science Daily: Pharmacology News

NOVEMBER 13, 2024

Glaciers that are within three miles of a volcano move nearly 50% quicker than average, a new study has found, which could help create early warning of future eruptions.

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BioPharma Drive: Drug Pricing

NOVEMBER 13, 2024

The California biotech has drawn partnerships with Eli Lilly and J&J on the promise of its approach to rebalancing the immune system.

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Drugs 70

Drug Patent Watch

NOVEMBER 13, 2024

The generic drug industry faces significant challenges, including unstable economics, supply chain disruptions, and intense competition. To remain competitive and profitable, generic drug manufacturers must adopt innovative strategies to optimize their manufacturing processes.

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Drugs 59

BioPharma Drive: Drug Pricing

NOVEMBER 13, 2024

With promising Phase 1 results in hand, Metsera hopes to develop a longer-lasting GLP-1 injection along with other types of obesity treatments.

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Treatment Drugs 62

Perficient: Drug Development

NOVEMBER 13, 2024

In today’s digital landscape, efficiently managing product information is vital for businesses to enhance customer satisfaction and drive sales growth. A robust Product Information Management (PIM) system with excellent integration features, like inriver, will streamline your PIM strategy. By utilizing the integration frameworks and APIs provided by inriver, businesses can ensure relevant, accurate, and consistent product information across all channels.

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Production Marketing Government 52

BioPharma Drive: Drug Pricing

NOVEMBER 13, 2024

The genetic testing firm will also close its drug development arm. CEO Anne Wojcicki said the cuts are necessary to “focus on the long-term success of our core consumer business.

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Drug Development Drugs 52

Perficient: Drug Development

NOVEMBER 13, 2024

We’re heading to Onederland! Optimizely’s Opticon 2024 is just around the corner. The three-day annual event is a can’t-miss for anyone in the Optimizely community. With countless breakout sessions, ample networking opportunities, hands-on workshops, inspiring keynotes, and an iconic closing celebration, Opticon promises to deliver something for everyone.

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Production Marketing 52

Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- A newly developed AI program can help doctors detect and potentially remove brain cancer that might otherwise be missed during surgery, a new study demonstrates.The AI, called FastGlioma, calculated how much residual.

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Doctors 52

Conversations in Drug Development Trends

NOVEMBER 13, 2024

By; Brooke Kaplan, Director, People Partner- HR Compliance & Human Capital Initiatives In April 2007, at 19 years old, I was a sophomore at the University of Maryland. I had always been relatively healthy, exercised recreationally, and worked part-time at the campus gym. I’d just returned from spring break at Disney World with my boyfriend (now husband), Zak, and we were gearing up for the Jewish holiday of Passover.

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Hospitals Clinical Trials Doctors Nurses 52

Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- High blood pressure is a rare health issue among teens, but U.S. case numbers are creeping upwards.Now, research published recently in the Journal of the American Heart Association, shows that healthy sleep can help keep.

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Research 52

Perficient: Drug Development

NOVEMBER 13, 2024

Perficient is proud to announce that we received awards from the 2024 eHealthcare Leaderships Awards for our outstanding projects that we completed for MVP Health Care and QuidelOrtho. MVP Health Care Informs and Impresses Users With an Optimized, Modern Website Best Overall Internet Site, Gold | A user-friendly architecture provides key information to help guide members to the right plan.

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Drugs.com

NOVEMBER 13, 2024

WEDNESDAY, Nov. 13, 2024 -- Bottoms up: The type of alcohol you prefer may say something about your lifestyle, new research reveals.Beer drinkers are more likely to have an unhealthy lifestyle than folks who prefer wine or liquor, scientists.

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Research 52

Metabolite Tales Blog

NOVEMBER 13, 2024

Major biotransformation routes of aficamten involving hydroxylation, onwards glucuronidation and gut metabolism Hypertrophic cardiomyopathy is a surprisingly common genetic heart disease, affecting 1:200 to 1:500 people in the US. Aficamten (CK-3773274) is a cardiac myosin inhibitor currently in phase 3 clinical development to treat this inherited disorder.

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Pharmacokinetics Small Molecule Production Clinical Development 52

Crown Bioscience

NOVEMBER 13, 2024

Following on from OX40 , our TNF superfamily posts continue with 4-1BB, another important target in T cell co-stimulation.

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