Fri.Sep 13, 2024

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'Self-Medicating' Gorillas Are Leading People to New Medicines

Drugs.com

FRIDAY, Sept. 13, 2024 -- Humans could learn a few medical tips from their gorilla cousins, a new study says.Four plants used by wild gorillas in Gabon have antibacterial and antioxidant properties, researcher reported Sept. 11 in the journal PLOS.

Research 116
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Moderna, trailing rivals, checks its RSV shot expectations

BioPharma Drive: Drug Pricing

During an investor presentation Thursday, executives admitted to being overly optimistic their vaccine could wrest significant market share away from GSK's and Pfizer's products this year.

Vaccine 108
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Ozempic, Mounjaro Help People With Type 1 Diabetes Control Blood Sugar, Lose Weight

Drugs.com

FRIDAY, Sept. 13, 2024 -- Initially approved to treat type 2 diabetes, Ozempic and Mounjaro also can help people with type 1 diabetes lose weight and control their blood sugar levels, a new study finds.Overweight or obese type 1 diabetics taking.

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Bacteria work together to thrive in difficult conditions

Science Daily: Pharmacology News

In a new study, researchers have determined through both statistical analysis and in experiments that soil pH is a driver of microbial community composition -- but that the need to address toxicity released during nitrogen cycling ultimately shapes the final microbial community.

Research 121
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Ozempic or Saxenda for Weight Loss: Which Works Best?

Drugs.com

FRIDAY, Sept. 13, 2024 -- Ozempic and its weight-loss cousin, Wegovy, outperform another longstanding weight-loss drug that targets the same hormone associated with blood sugar and appetite, a new study finds.Ozempic and Wegovy (semaglutide).

Drugs 116
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Folded or cut, this lithium-sulfur battery keeps going

Science Daily: Pharmacology News

Most rechargeable batteries that power portable devices, such as toys, handheld vacuums and e-bikes, use lithium-ion technology. But these batteries can have short lifetimes and may catch fire when damaged. To address stability and safety issues, researchers have designed a lithium-sulfur (Li-S) battery that features an improved iron sulfide cathode.

Research 118

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Beyond data: Humanizing clinical research with Avacare

Fierce BioTech

Navigating today’s rapidly evolving clinical trial landscape can be tough. | With intricate protocols and shifting regulatory demands, it’s more difficult than ever to find and keep participants, as well as gather reliable data.

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Boar's Head Will Close Virginia Plant Linked to Listeria-Tainted Deli Meats

Drugs.com

FRIDAY, Sept. 13, 2024 -- Boar's Head announced Friday that its Jarratt, Va. deli meat manufacturing plant, found to be the source of a deadly outbreak of listeria infections, will be closed indefinitely.Boar's Head added that it also believes it.

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Early dark energy could resolve cosmology's two biggest puzzles

Science Daily: Pharmacology News

Physicists propose that a mysterious force known as early dark energy could solve two of the biggest puzzles in cosmology and fill in some major gaps in our understanding of how the early universe evolved.

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Source of Missouri Bird Flu Case Still Unknown, Could Be a 'One-Off': CDC

Drugs.com

FRIDAY, Sept. 13 , 2024 -- In a case that continues to confound scientists, U.S. health officials said Thursday that they still don't know how a Missouri patient caught the bird flu and that the case may just be a rare anomaly. As bird flu.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Plant-derived secondary organic aerosols can act as mediators of plant-plant interactions

Science Daily: Pharmacology News

A new study reveals that plant-derived secondary organic aerosols (SOAs) can act as mediators of plant-plant interactions. This research was conducted through the cooperation of chemical ecologists, plant ecophysiologists and atmospheric physicists.

Research 111
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How Clinical Trial Trends are Redefining Drug Development

Quanticate

With the implementation of technology rapidly increasing, stricter regulatory standards, and growing demand for innovative treatments, the trends within the industry continue to evolve, impacting the future of clinical trials both positively and negatively. In our article, we cover the key trends that have been shaping clinical trials so far in 2024, and those that are predicted to continue into 2025.

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A-Fib Risk Drops Soon After Quitting Smoking

Drugs.com

FRIDAY, Sept. 13, 2024 -- Smokers who make the decision to quit will see almost immediate health benefits, including a quick drop in their risk for atrial fibrillation, new research shows.“The findings provide a compelling new reason to show c.

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ATICAPRANT

New Drug Approvals

ATICAPRANT JNJ-67953964 , WHO 10582 1174130-61-0 BENZAMIDE, 4-(4-(((2S)-2-(3,5-DIMETHYLPHENYL)-1-PYRROLIDINYL)METHYL)PHENOXY)-3-FLUORO- C 26 H 27 FN 2 O 2 , 418.512 4-[4-[[(2 S )-2-(3,5-Dimethylphenyl)-1-pyrrolidinyl]methyl]phenoxy]-3-fluorobenzamide (ACI) ( S )-4-(4-((2-(3,5-Dimethylphenyl)pyrrolidin-1-yl)methyl)phenoxy)-3-fluorobenzamide 4-(4-{[(2 S )-2-(3,5-dimethylphenyl)pyrrolidin-1-yl]methyl}phenoxy)-3-fluorobenzamide Aticaprant CERC 501 JNJ 67953964 JNJ 67953964AAA LY 2456302 S -Aticapran

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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1 in 3 Store-Bought Cinnamon Samples Tested Have Elevated Lead Levels

Drugs.com

FRIDAY, Sept. 13, 2024 -- One third of cinnamon products tested by Consumer Reports contained elevated levels of lead, the watchdog agency warned Thursday.The finding follows concerns about metals in foods after tainted cinnamon applesauce poisoned.

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Towards the realization of compact and portable nuclear clocks

Science Daily: Pharmacology News

The low-energy excited state of thorium-229 (229Th) isotope nucleus has recently gained much attention owing to it being an ideal candidate for ultra-precise nuclear clocks. Building such high-precision clocks requires an acute understanding of the excitation and de-excitation state of the nucleus. In this view, researchers have designed 229Th-doped vacuum ultraviolet (VUV) transparent CaF2 crystals.

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Subcutaneous Tecentriq gets FDA OK; Gilead shot succeeds in second HIV trial

BioPharma Drive: Drug Pricing

Roche has now beat Merck and Bristol Myers to market with its under-the-skin immunotherapy. Elsewhere, Sanofi bought into radiopharmaceuticals and Mene Pangalos joined Biogen's board.

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Part three: 15 pragmatic guidelines to handle data quality issues

Drug Target Review

In the first article in this series, published Wednesday 14 August, we discussed the importance that data quality plays in the effectiveness of data analyses by Machine Learning (ML) and AI. In part two, we looked at the impact that poor data quality can have on ML models. Here, we outline 15 pragmatic guidelines to ensure better data quality in early drug discovery and to identify potential issues with compromised data.

Science 59
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Highlights From the Final ICH Drug Interactions Guideline

Fierce BioTech

Highlights From the Final ICH Drug Interactions Guideline pesurya Fri, 09/13/2024 - 11:39 Thu, 10/31/2024 - 11:00 Resource Type Webinar Brian Ogilvie Graham Dyck Duration 60 Minutes The ICH M12 Guideline was finalized on May 21st, 2024, after extensive review of industry and other comments. The Guideline was the culmination of the extensive work by the Expert Working Group.

Drugs 52
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XM Cloud content migration: connecting external database

Perficient: Drug Development

Technical Challenge The key idea of proposed approach is to create an instance with two databases attached: Sitecore 9 Legacy New Sitecore 10 XM Cloud There could be two potential ways of doing this: Restore backup of XM Cloud database to a legacy XP of the desired version with content databased already attached/restored. That would not works since XP 9.3 neither knows about XM Cloud schema, nor is capable to handle Items as Resource which were invented in XP 10.1.

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Leveraging Whole-Genome Sequencing for Advanced Drug Discovery

Fierce BioTech

Leveraging Whole-Genome Sequencing for Advanced Drug Discovery pesurya Fri, 09/13/2024 - 11:18 Wed, 10/23/2024 - 11:00 Resource Type Webinar Keren Carss Joseph Maranville Dirk Paul Leeland Ekstrom Geoff Nilsen Duration 60 Minutes Large, deeply characterized patient cohorts are one of the most promising resources today for understanding disease biology and developing new medicines.

Drugs 52
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Blood Sugar Worries Keep Many With Type 1 Diabetes From Exercise

Drugs.com

FRIDAY, Sept. 13, 2024 -- Fear of a having a low blood sugar crash dissuades many people with type 1 diabetes from getting the exercise they need, a new study finds.However, people were more likely to engage in exercise if their doctor discussed.

Doctors 52
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Wellness Camp’ 24 at Perficient

Perficient: Drug Development

The greatest wealth is health. Perficient came up with this “wellness at work, wellness in life” initiative to provide basic health care, Eye care and dental care to its employees. Perficient proves its value for People and prioritized the wellness of its people. Perficient joined hands with Kauvery hospital for basic health care, Dr Agarwal’s hospital for eye care and Clove dental for dental care.

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Social Media Linked to Eating Disorders in Kids and Young Teens

Drugs.com

FRIDAY, Sept. 13, 2024 -- Excessive time spent on social media increases children's and teens’ risk of developing an eating disorder, a new study warns.Each additional hour of total screen time or social media use raises the likelihood that a kid o.

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GoodRx: Evolving & Expanding Integrated Platform Partnerships to Drive Access, Affordability & Outcomes

Drug Channels

Today’s guest post comes from Rick Fry, VP of Strategic Development at GoodRx. Rick explains why patients and pharmaceutical manufacturers now pay a greater share of prescription costs. He outlines GoodRx's services that address the twin challenges when the patient is the payer and the manufacturer faces intense gross-to-net pressures. To learn more, download the GoodRx case study: GoodRx Integrated Platform Solutions: Patient Navigator + Integrated Copay Card.

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Florida Abortion Rate Fell After 6-Week Ban Took Hold

Drugs.com

FRIDAY, Sept. 13, 2024 -- Florida’s six-week abortion ban caused the state’s abortion rate to drop dramatically, new research shows.Abortions in Florida dropped to an estimated 5,630 in May and 5,200 in June, a 30% and 35% decrease from the average.