Wed.Nov 27, 2024

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Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry

Science Daily: Pharmacology News

A tiny, four-fingered 'hand' folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, researchers report. Dubbed the NanoGripper, the nanorobotic hand also could be programmed to interact with other viruses or to recognize cell surface markers for targeted drug delivery, such as for cancer treatment.

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Diabetes Drug Metformin Might Help Fight Lung Cancer

Drugs.com

WEDNESDAY, Nov. 27, 2024 -- Already the go-to drug of choice for millions with type 2 diabetes, metformin might also fight lung cancer if those patients have it as well, new research shows.Metformin appears to help boost the benefits of.

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Clinical trial reveals twice-yearly injection to be 96% effective in HIV prevention

Science Daily: Pharmacology News

Recent results from a recent clinical trial indicate that a twice-yearly injection of Lenacapavir offers an overall 96% reduced risk of acquiring HIV. This makes Lenacapavir significantly more effective than the standard daily oral PrEP (pre-exposure prophylaxis).

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Irregular Sleep Might Raise Odds for Heart Attack, Stroke

Drugs.com

WEDNESDAY, Nov. 27, 2024 -- Folks with irregular sleep patterns might have an increased risk of a heart attack or stroke, a new study says.People who doze off and wake up at extremely varied times day by day have a 26% increased risk of a.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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First new treatment for asthma attacks in 50 years

Science Daily: Pharmacology News

A recent trial finds an injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30%.

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More Trending

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Moving 'hotspot' created world's longest straight underwater mountain belt

Science Daily: Pharmacology News

New research has revealed that the Ninetyeast Ridge -- the Earth's longest straight underwater mountain chain -- formed through a different process than previously believed. Stretching 5000 km along the Indian Ocean's 90-degree east longitude and nearly matching the length of North America's Rocky Mountains, the ridge offers crucial new insights into the movement of the Earth's tectonic plates.

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Scientists Find Way to Deliver Medicines Across Brain's Protective Barrier

Drugs.com

WEDNESDAY, Nov. 27, 2024 -- The blood-brain barrier is a natural membrane that protects your brain from toxins and germs.Unfortunately, this barrier also hampers the delivery of important medicines and therapies into the brain.But researchers now.

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Fossil dung reveals clues to dinosaur success story

Science Daily: Pharmacology News

Researchers have been able to identify undigested food remains, plants and prey in the fossilized feces of dinosaurs. These analyses of hundreds of samples provide clues about the role dinosaurs played in the ecosystem around 200 million years ago.

Research 278
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Holiday Travel With a Loved One With Dementia: An Expert Offers Tips

Drugs.com

WEDNESDAY, Nov. 27, 2024 -- Thanksgiving travel is a must for millions of Americans, but those plans will be complicated for some because they’re traveling with a loved one who has Alzheimer’s disease or dementia.“A family trip to visit a loved one.

Disease 245
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Early North Americans made needles from fur-bearers

Science Daily: Pharmacology News

Paleoindians at Wyoming's LaPrele mammoth site made needles from the bones of fur-bearers, likely to creat garments from the animals' furs to keep warm in a cool climate.

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Nerve Stimulation Device Might Ease Long COVID Symptoms

Drugs.com

FRIDAY, Nov. 29, 2024 -- A painless nerve-zapping device called Transcutaneous Electrical Nerve Stimulation (TENS) has long been used to ease arthritis, back pain and other ailments.Now, researchers say TENS might also work to ease the fatigue and.

Research 244
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Discovering the traits of extinct birds

Science Daily: Pharmacology News

Analysis of 216 extinct species by biologists found birds endemic to islands, occupied ecologically specific niche, lacking flight, with large bodies and sharply angled wings were the ones likely to disappear the soonest after 1500.

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Zepbound Slashes Diabetes Risk in Obese Users

Drugs.com

WEDNESDAY, Nov. 27, 2024 -- The cutting-edge weight-loss drug Zepbound can protect obese people from developing type 2 diabetes, a new clinical trial has found.Zepbound reduced the risk of diabetes in obese prediabetic patients by more than 90%.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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'Genetic time machine' reveals complex chimpanzee cultures

Science Daily: Pharmacology News

Chimpanzees are known for their remarkable intelligence and use of tools, but could their cultures also evolve over time like human cultures? A new, multidisciplinary study suggests that some of their most advanced behaviors may have been passed down and refined through generations.

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How Intra-Cellular surprised Wall Street by breaking character

BioPharma Drive: Drug Pricing

The biotechnology company, which sees itself as "pretty conservative," recently put out an ambitious long-term revenue forecast for its schizophrenia and depression medicine Caplyta.

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How to Scale Up with Cohere: Insights from Aidan Gomez

BenchSci

Last month, we welcomed Aidan Gomez, CEO and Co-founder of Cohere, for our Scale Up series. As a leader in AI, Aidan co-authored the influential " Attention is All You Need " paper during his time at Google and has since co-founded Cohere , the leading data security-focused enterprise AI company. With the explosion of advancements in AI and its growing impact on industries worldwide, including drug discovery, our team was eager to hear Aidan’s unique technical perspective on building and scaling

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Heart Trouble Harms Men's Brains Far Sooner Than Women's

Drugs.com

WEDNESDAY, Nov. 27, 2024 -- Men with heart risk factors tend to lose their brain health more quickly than women with similar heart risks, a new study finds.These men face brain decline as early as their mid-50s, while women are most susceptible.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Kronos, Idorsia plan layoffs; PTC shelves ALS drug

BioPharma Drive: Drug Pricing

Kronos is cutting 83% of its workforce, while Idorsia is considering eliminating as many as 270 jobs. Elsewhere, PTC disclosed negative Phase 2 results for its ALS drug candidate utreloxastat.

Drugs 139
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Soccer 'Headers' Could Pose Danger to Brains

Drugs.com

WEDNESDAY, Nov. 27, 2024 -- Bouncing a soccer ball off the head during play could be doing real damage to the brain, a new study suggests.MRI brain scans of male and female soccer athletes suggests that lots of "heading" could damage areas of the.

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Sarepta rebuilds drug pipeline with Arrowhead deal

BioPharma Drive: Drug Pricing

A broad licensing and research alliance will hand Sarepta four clinical-stage candidates, while Arrowhead receives $500 million in cash and another $325 million in equity investment.

Licensing 139
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Pharma AI is Changing Clinical Trials by Optimizing Patient Selection

Reprocell

In recent years, the pharmaceutical industry has increasingly harnessed artificial intelligence (AI) to make clinical trials more efficient and effective. One of the most powerful applications of AI in this space is its ability to help researchers identify patient groups most likely to benefit from specific drugs. By making patient selection and recruitment processes more targeted, AI-driven tools not only improve trial outcomes but also accelerate the journey of new drugs to market.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Cover Image

Chemical Biology and Drug Design

Cover Image © molekuul_be/Shutterstock.

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Things You Should Know Before Hiring a CDMO

DS in Pharmatics

Learn the critical factors to consider before partnering with a CDMO, ensuring your drug development project aligns with the right expertise and capabilities.

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U.S. Abortion Numbers Dipped Slightly in 2022

Drugs.com

WEDNESDAY, Nov. 27, 2024 -- The rate and number of abortions among U.S. women took a slight dip in 2022 compared to 2021, according to the latest data from the U.S. Centers for Disease Control and Prevention (CDC).In late June of 2022, the U.S.

Disease 246
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Identification of a covalent NEK7 inhibitor to alleviate NLRP3 inflammasome-driven metainflammation

Covalent Modifiers

Jin, X., Yang, Y., Liu, D. et al. Cell Commun Signal 22 , 565 (2024). [link] Aberrant activation of NLRP3 inflammasome is associated with a variety of inflammatory diseases. Advances in understanding the molecular mechanisms of NLRP3 inflammasome have revealed that NEK7 is an essential component for its activation, but the development of drugs specifically targeting NEK7 remains challenging.

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Perficient Colleagues Donate 11,000+ Pounds of Food and 46,000+ Meals During Hunger Action Month

Perficient: Drug Development

Perficient has a long-standing reputation as a philanthropic organization with colleagues who are driven and passionate about making a collective difference. In the spirit of giving back, our Giving Employee Resource Group (ERG) partnered with Feeding America for the third year in a row in support of Hunger Action Month (HAM), a global campaign that seeks to spread awareness and fight food insecurity.

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