Drug Discovery World

APRIL 30, 2024

Download this In Focus eReport to gain a full understanding of the current market for CGTs and the areas of greatest commercial potential for the future. The eReport includes: In-depth analysis of regional markets An overview of the likely challenges and opportunities The benefits of allogeneic CAR-T cell therapies The latest advances and where could CGTs take us in the future The post Cell and gene therapy: Global Innovation and Opportunity appeared first on Drug Discovery World (DDW).

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Science Daily: Pharmacology News

APRIL 30, 2024

Researchers have discovered over a hundred new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure. In total, over 2,000 independent genetic signals for blood pressure are now reported, demonstrating that blood pressure is a highly complex trait influenced by thousands of different genetic variants.

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Research 121

Drug Discovery World

APRIL 30, 2024

Glen Clova Scientific has closed a £4 million (approximately $5 million) seed financing round, led by Norcliffe Capital together with investment from DSW Ventures, TRICAPITAL Angels and Scottish Enterprise. Glen Clova Scientific was founded in 2022 as a spin out from the University of Dundee to develop a new generation of active biologic drugs for chronic inflammatory and autoimmune disorders.

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Virus Drug Development Production Treatment 130

BioPharma Drive: Drug Pricing

APRIL 30, 2024

The funds will help the cancer-focused startup Enlaza bring “several development candidates” towards human testing in the next few years, its CEO said.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

APRIL 30, 2024

The low toxicity and high specificity of monoclonal antibodies (mAbs) continue to make them an appealing target for clinical research and investment. During 2023, 16 antibody therapeutics were granted approvals in the US or EU, either for the first time or for a new indication, covering uses as diverse as cancer, Alzheimer’s disease, diabetes and respiratory syncytial virus.

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BioPharma Drive: Drug Pricing

APRIL 30, 2024

Supply continues to be tight, however, and the company anticipates further sales growth to be limited by how quickly it can bring on additional production capacity.

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Production Drugs 120

Science Daily: Pharmacology News

APRIL 30, 2024

Researchers have developed a chemical process using plasma that could create sustainable jet fuel from methane gas emitted from landfills, potentially creating a low-carbon aviation industry.

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Research 113

Drug Discovery World

APRIL 30, 2024

Four new LifeArc Translational Centres for Rare Diseases have been created to give people living with rare medical conditions access to improved tests and treatments. The virtual centres will focus on areas where there are significant unmet needs. They aim to tackle barriers that ordinarily prevent new tests and treatments reaching patients with rare diseases and speed up the delivery of rare disease treatment trials.

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Research Disease Trials Treatment 130

Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2024 -- Kids who don’t like vaccination shots might soon have an alternative in a painless skin patch, researchers say.More than 90% of 190 Gambian infants were protected from measles and all were protected from rubella after.

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Vaccine Research 111

Drug Discovery World

APRIL 30, 2024

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Steve Worland, CEO of eFFECTOR. eFFECTOR is a company targeting three distinct targets central to the eIF4F translation initiation complex: MNK, eIF4A and eIF4E.

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Regulations Science Treatment Drugs 130

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Science Daily: Pharmacology News

APRIL 30, 2024

A new type of bioplastic could help reduce the plastic industry's environmental footprint. Researchers have developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores that, when exposed to nutrients present in compost, germinate and break down the material at the end of its life cycle.

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Research 108

Drug Discovery World

APRIL 30, 2024

Traditional drug discovery is time-consuming, and expensive, and numerous industry studies are showing a year-on-year decrease in return on investment from R&D efforts across the board. Join DDW and FUJIFILM Wako on 24 May 3PM BST to learn more about how AI-AAM (AI-Amino-Acid Mapping), its new proprietary scaffold-hopping method based on AI and chemical simulation techniques, can be used to address this challenge, accelerating the identification of hit compounds and improvements in compound

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Small Molecule Drugs Marketing Research 130

Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2023 -- Teens who vape frequently are exposing themselves to harmful metals like lead and uranium, a new study finds.Lead levels in urine are 40% higher among intermittent vapers and 30% higher among frequent vapers, compared to.

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Science Daily: Pharmacology News

APRIL 30, 2024

A four-legged robot trained with machine learning has learned to avoid falls by spontaneously switching between walking, trotting, and pronking -- a milestone for roboticists as well as biologists interested in animal locomotion.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2024 -- All women should start getting mammograms every other year beginning at age 40, the nation’s top panel of preventive health experts announced Tuesday.About 20% more lives can be saved from breast cancer by moving the.

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Science Daily: Pharmacology News

APRIL 30, 2024

A completely novel way to develop 'surpamolecules' for drug discovery could have application in immunotherapy as well as this breakthrough design for an anticoagulant with on-demand reversibility.

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Drugs 102

Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2024 -- At what age does loneliness strike adults the hardest?A new review maps it out, finding that people are more lonely as young adults, grow less lonely as they approach middle age, and then fall back into loneliness in old.

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Science Daily: Pharmacology News

APRIL 30, 2024

An estimated 168 billion gallons of wastewater -- or produced water -- is generated annually by the Permian Basin fracking industry, according to a 2022 report. The major waste stream has proved both difficult and costly to treat because of the chemical complexity of the water.

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Virus 98

Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2024 -- H5N1 avian "bird" flu is making headlines this week, with new reports finding inactive virus detected in 1 in 5 U.S. milk samples. That means the virus is infecting mammals such as dairy cows, and now researchers report.

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Virus Research 98

Science Daily: Pharmacology News

APRIL 30, 2024

Researchers have successfully used NASA's James Webb Space Telescope to map the weather on the hot gas-giant exoplanet WASP-43 b.

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Research 115

Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2024 -- As bird flu continues to spread among dairy cows, the U.S. Department of Agriculture said Monday it is now testing ground beef for any presence of the virus.The agency said it is sampling ground beef bought in grocery.

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Science Daily: Pharmacology News

APRIL 30, 2024

NASA's James Webb Space Telescope has captured the sharpest infrared images to date of a zoomed-in portion of one of the most distinctive objects in our skies, the Horsehead Nebula. These observations show the top of the 'horse's mane' or edge of this iconic nebula in a whole new light, capturing the region's complexity with unprecedented spatial resolution.

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Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2024 -- At major medical centers across the southeast, 1 in every 20 visits to emergency departments involve people who are homeless or face "housing insecurity," a new U.S. study finds.Concerns of suicide was the leading.

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BioPharma Drive: Drug Pricing

APRIL 30, 2024

Large and small drugmakers are vying for a piece of what analysts view as one of the biggest market opportunities in the pharma industry's history. Here’s what’s coming next.

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Marketing Drugs 89

Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2024 -- The benefits of physical fitness for kids spill over into their mental health, new research shows.Getting plenty of exercise may guard against depressive symptoms, anxiety and attention-deficit hyperactivity disorder.

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Science Daily: Pharmacology News

APRIL 30, 2024

The link between massive flood basalt volcanism and the end-Triassic (201 million years ago) mass-extinction is commonly accepted. However, exactly how volcanism led to the collapse of ecosystems and the extinction of entire families of organisms is difficult to establish. Extreme climate change from the release of carbon dioxide, degradation of the ozone layer due to the injection of damaging chemicals, and the emissions of toxic pollutants, are all seen as contributing factors.

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Drugs.com

APRIL 30, 2024

TUESDAY, April 30, 2024 -- As the battle over abortion continues to rage in the courts and American politics, a new report estimates that one in every four U.S. women will undergo the procedure during their lifetime. The study was issued by.

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addgene Blog

APRIL 30, 2024

The triple T’s of biology are transformations, transfections, and transductions! In this blog we will discuss all things transductions. If you’ve ever wondered how they are different from or similar to the other Ts, we have your answers. If you know the basics but are here because you want to know the intricacies of transductions, we've got you covered there too.

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BioPharma Drive: Drug Pricing

APRIL 30, 2024

Increasing the production capacity for Zepbound and Mounjaro is “the most ambitious expansion plan in our company’s history,” said CEO David Ricks.

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Production Drugs 73

FDA Law Blog: Biosimilars

APRIL 30, 2024

By Lisa M. Baumhardt, Senior Medical Device Regulation Expert — FDA recently issued a draft guidance on Requests for Feedback and Meetings for Medical Device Submissions: The Q-Submission Program , which included some changes over the existing guidance which could have a negative impact on future pre-submissions. The draft guidance attempted to clarify when a Sponsor’s question may be more appropriate for more informal communication.

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BioPharma Drive: Drug Pricing

APRIL 30, 2024

The new policy aims to ensure important diagnostics remain available to patients, but some experts caution the increased regulatory burden could slow access to testing.

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Drug Patent Watch

APRIL 30, 2024

MYRBETRIQ GRANULES (mirabegron) Apgdi Patent: 7,982,049 Expiration: May 4, 2024 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.

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Pharmaceuticals Drugs 59

thought leadership

APRIL 30, 2024

To reduce frustration within a promotional review committee (PRC) , the PRC must be a well-oiled machine firing on all cylinders and working at optimum capacity. How does a PRC achieve this? By developing and implementing best practices.

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Science 59

Broad Institute

APRIL 30, 2024

Social By Rose Circeo April 30, 2024 Breadcrumb Home Social STP on the Broad patio in the summertime of 2022. Lab members gathering to watch the partial 2024 eclipse at the Broad! A goodbye party for Serwah Danquah (alumni) before she heads off to grad school at UW. Congrats Serwah! The team in 2020 - great work at keeping that distance, everyone.

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