Thu.May 02, 2024

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Significant new discovery in teleportation research -- Noise can improve the quality of quantum teleportation

Science Daily: Pharmacology News

Researchers succeeded in conducting an almost perfect quantum teleportation despite the presence of noise that usually disrupts the transfer of quantum state.

Research 138
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#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower

Broad Institute

#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower By Allessandra DiCorato May 2, 2024 Breadcrumb Home #WhyIScience Q&A: How a computational biologist balances work with life as an elite rower Liz Martin reflects on how her career in cancer biology complements her intense training on the water. By Allessandra DiCorato May 2, 2024 Credit: Lisa Worthy Liz Martin, an elite rower and a computational biologist at the Broad, in a lightweight women's quad at the 2

Science 124
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Structural and molecular insights from dual inhibitors of EGFR and VEGFR2 as a strategy to improve the efficacy of cancer therapy

Chemical Biology and Drug Design

Simultaneous inhibition of EGFR and VEGFR2 may improve the efficacy of cancer treatment. Understanding the macromolecular structures, activation mechanism, and pharmacophore features of both kinase inhibitors and their selectivity is essential in designing dual inhibitors of EGFR and VEGFR2. Abstract Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor 2 (VEGFR2) are known as valid targets for cancer therapy.

Therapies 100
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Reunion raises over $100M to build a better psychedelic drug

BioPharma Drive: Drug Pricing

The funding will help Reunion pay for a mid-stage study testing its most advanced medicine — essentially a synthetic version of the hallucinogenic psilocin — in women with postpartum depression.

Drugs 124
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Scientists track 'doubling' in origin of cancer cells

Science Daily: Pharmacology News

Working with human breast and lung cells, scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer cells.

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Delphia starts up with $67M to make a new type of cancer drug

BioPharma Drive: Drug Pricing

Delphia is developing medicines designed to overstress certain cellular pathways to the point tumor cells die, an approach the biotech calls “activation lethality.

Drugs 124

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Cell Line Services FAQ

Crown Bioscience

This post delves into some frequently asked questions about Omni Screen and its unique capabilities in providing compliant, large-scale cell line screening solutions that are not only cutting-edge but also aligned with industry standards and regulations. Whether you're a researcher, a biotech professional, or someone keen on understanding the nuances of cell line screening, this discussion will provide valuable insights into how Crown Bioscience can support your scientific endeavors.

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Sugar-based catalyst upcycles carbon dioxide

Science Daily: Pharmacology News

New catalyst is made from an inexpensive, abundant metal and table sugar. Catalyst converts carbon dioxide (CO2) into carbon monoxide, a building block for producing a variety of useful chemicals including syngas. With recent advances in carbon capture technologies, post-combustion carbon capture is becoming a plausible option to help tackle the global climate change crisis.

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Advancing Clinical Data Management into a New Era

Quanticate

Innovative strategies paving the way for enhanced data quality, integrity and streamlined data validation and cleaning. The way we clean and validate data within clinical trials is continuously evolving, more than ever now with the advancements in technology that we are seeing across this industry year on year. These technological developments are reshaping the way data is handled, leading to improvements in the accuracy and efficiency of data.

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Random robots are more reliable

Science Daily: Pharmacology News

New algorithm encourages robots to move more randomly to collect more diverse data for learning. In tests, robots started with no knowledge and then learned and correctly performed tasks within a single attempt. New model could improve safety and practicality of self-driving cars, delivery drones and more.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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More Evidence Supports Psilocybin's Antidepressant Powers

Drugs.com

THURSDAY, May 2, 2024 -- The active chemical in magic mushrooms could prove to be a powerful antidepressant, a new review finds.Psilocybin outperformed a variety of “control” treatments in easing symptoms of depression, researchers reported May.

Treatment 105
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Novartis to buy Mariana Oncology in radiopharmaceutical expansion

BioPharma Drive: Drug Pricing

The $1 billion dollar acquisition will add to Novartis’ pipeline of the targeted radiation drugs, giving it a potential lung cancer treatment.

Treatment 115
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MRNA Vaccine Fights Deadly Brain Tumor in Small Trial

Drugs.com

THURSDAY, May 2, 2024 -- An experimental cancer vaccine can quickly reprogram a person’s immune system to attack glioblastoma, the most aggressive and lethal form of brain cancer, a small, preliminary study has found.The cancer vaccine is based.

Vaccine 105
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Balancing Work and Home Life: 4 Ways to Support Better Mental Health for Mothers

Perficient: Drug Development

I recently became a mother for the third time, welcoming a beautiful baby girl in July 2023. Stepping into the whirlwind of newborn life with two other children in tow felt like diving headfirst into uncharted waters! Balancing the needs of three young humans has become my daily adventure, filled with equal parts chaos and love. Mo therhood , whether it’s the first or fifth time, is a beautiful yet wildly demanding journey that nearly always involves juggling multiple responsibilities simultane

Nurses 98
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Johnson & Johnson Will Pay $6.5 Billion to Settle Talc Ovarian Cancer Lawsuits

Drugs.com

THURSDAY, May 2, 2024 -- Johnson & Johnson announced Wednesday that it would pay out more than $6.5 billion over the next 25 years to settle existing lawsuits claiming that its talc-containing products caused ovarian cancer. The settlement.

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Novo sees Wegovy sales dip on lower price, tight supply

BioPharma Drive: Drug Pricing

First quarter sales of the in-demand obesity drug were down slightly compared to the fourth quarter last year, as the company tries to meet demand.

Drugs 102
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Economy, Election Spur Rising Anxiety Among Americans in 2024

Drugs.com

THURSDAY, May 2, 2024 -- A looming presidential election, continued economic struggles and the threat of gun violence have a rising number of Americans more anxious this year compared to last, a new poll finds.The survey, conducted in early April.

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Bracing for Impact: The Future of Hub, PAP, and Affordability Programs Under the Inflation Reduction Act

Drug Channels

Today’s guest post comes from Chris Dowd, Senior VP of Market Development at ConnectiveRx. Chris explains how the Inflation Reduction Act of 2022 (IRA) will impact hub, patient assistance programs (PAP), and affordability programs. He discusses steps manufacturers can take to accommodate the anticipated budget reductions while maintaining access and affordability for patients.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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EPA Earmarks $3 Billion to Replace Lead Pipes Nationwide

Drugs.com

THURSDAY, May 2, 2024 — The U.S. Environmental Protection Agency (EPA) said it will spend $3 billion to help states and territories identify and replace lead water pipes."The science is clear, there is no safe level of lead exposure, and the.

Science 105
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Progress Toward a New GAD Treatment Paradigm

Fierce BioTech

Robert Barrow, Chief Executive Officer of MindMed | Generalized anxiety disorder afflicts millions however, the latest treatment was approved in 2007. Now MindMed is advancing a new treatment paradigm.

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A Third of Young Adults Still Believe 'Tan Is Healthier' Myth: Survey

Drugs.com

THURSDAY, May 2, 2024 -- Brianna Starr, 29, didn’t think twice about sunbathing without sunscreen, hoping to get a golden tan that to many connotes health and beauty.But when her sister was diagnosed with melanoma at the age of 19, she got.

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Performing In Vivo CRISPR Screens Using the FITS Approach

addgene Blog

FITS In vitro CRISPR screens in immune cells have identified many putative regulators of immunity. However, in vitro screens cannot faithfully model the complex spatial, cellular, metabolic, and cytokine microenvironment that exists in vivo. Over the past five years, in vivo CRISPR screens have been used to interrogate T cells, an important immune cell type, in more complex and physiological microenvironments.

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AI Won't Replace ER Doctors Anytime Soon: Study

Drugs.com

THURSDAY, May 2, 2024 -- Artificial intelligence might be able to help doctors by filling out rote paperwork, but it’s not going to be useful in the ER anytime soon, a new study shows.OpenAI’s ChatGPT program provided inconsistent conclusions.

Doctors 97
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Moderna ends gene editing alliance with Metagenomi

BioPharma Drive: Drug Pricing

Metagenomi said the companies’ decision to part ways followed a “strategic prioritization” undertaken by Moderna, which has made several investments in gene editing research in recent years.

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Sleep Apnea Linked With Late-Life Epilepsy

Drugs.com

THURSDAY, May 2, 2024 -- Add one more damaging consequence of sleep apnea to the list: New research suggests it's related to late-life epilepsy. Late-onset epilepsy is defined as seizures that tend to begin only after the age of 60. The condition.

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Connecting SFCC with Other Clouds

Perficient: Drug Development

Are you looking to revolutionize your e-commerce strategy? Look no further than Salesforce Commerce Cloud (SFCC) and its powerful integrations with other Salesforce clouds. SFCC’s ability to seamlessly connect with Marketing Cloud, Service Cloud, and Sales Cloud opens up a world of possibilities for businesses seeking to enhance their customer engagement, drive sales, and optimize operations.

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Day Care Pick-Up Often Involves Sugary Snacks, Study Finds

Drugs.com

THURSDAY, May 2, 2024 -- Giving your kid a drink, snack or small bag of fast food on the way home from day care might distract them during a busy commute, but it’s not doing their daily diet any favors, a new study warns.The hour after kids are.

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Wearables in Clinical Trials: Real Benefits Beyond the Hype

Crucial Data Solutions

In clinical research, innovations in technology are moving us down an exciting path, transforming traditional methodologies and paving the way. The post Wearables in Clinical Trials: Real Benefits Beyond the Hype appeared first on Crucial Data Solutions.

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No Sign of Bird Flu in Ground Beef, USDA Says

Drugs.com

THURSDAY, May 2, 2024 -- After investigation, the U.S. Department of Agriculture said Wednesday that the nation's ground beef supply is so far testing negative for the presence of H5N1 avian flu.In a statement, the agency said that its Food Safety.

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Stars and Scars… Some Lessons Learned About Leadership

LifeSciVC

By Arthur O. Tzianabos, PhD, CEO of Lifordi Immunotherapeutics, as part of the From the Trenches feature of LifeSciVC As the biotech industry continues to pick up steam, I have been getting a number of phone calls from folks in my network who are looking for CEO roles and from recruiters who are looking to hire good people. It got me thinking (again) about leadership styles I have encountered in my 30+ years in biotech.

Science 61
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U.S. Maternal Deaths Declined in 2022

Drugs.com

THURSDAY, May 2, 2024 -- The number of American women who died at or soon after childbirth declined significantly in 2022, the latest government data shows, but the rate is still higher than pre-pandemic levels.The report from the U.S. National.

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BridgeBio spinout launches with $200M for KRAS cancer drugs

BioPharma Drive: Drug Pricing

The company, BridgeBio Oncology Therapeutics, has one drug in the clinic and hopes to soon advance two other candidates.

Drugs 72
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The Importance of Licensed Cell Lines for Cancer Research

Crown Bioscience

This post delves into some frequently asked questions about Omni Screen ™ and its unique capabilities in providing compliant, large-scale cell line screening solutions that are not only cutting-edge but also aligned with industry standards and regulations. Whether you're a researcher, a biotech professional, or someone keen on understanding the nuances of cell line screening, this discussion will provide valuable insights into how Crown Bioscience can support your scientific endeavors.