Mon.Nov 25, 2024

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Stroke Guidelines Updated, With Focus on Women and GLP-1s

Drugs.com

MONDAY, Nov. 25, 2024 -- Women, especially those who had high blood pressure during pregnancy or entered menopause before age 45, are among those with a greater risk for stroke.They and other high-risk groups are the focus of new stroke prevention.

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Pandrug-resistant bacteria from the war in Ukraine are extremely pathogenic

Science Daily: Pharmacology News

It has been a year ago since bacteria from war-wounded at hospitals in Ukraine were analyzed. The study showed that some of the bacteria types had total resistance to antibiotics. Now, the same researchers have examined the infectiousness of the bacteria. 'The bacterium 'Klebsiella pneumoniae', which is resistant to all antibiotics, is also particularly aggressive and dangerous,' says the lead author of the study.

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Biohaven muscle drug misses goal of SMA study, but advances in obesity

BioPharma Drive: Drug Pricing

The setback likely removes one competitor to an emerging spinal muscular atrophy medicine from Scholar Rock, but sets the stage for a pair of readouts with implications for weight loss research.

Drugs 67
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New study reveals the explosive secret of the squirting cucumber

Science Daily: Pharmacology News

A team has solved a mystery that has intrigued scientists for centuries: how does the squirting cucumber squirt? The findings were achieved through a combination of experiments, high-speed videography, image analysis, and advanced mathematical modelling.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Could the Common Thyroid Medicine Levothyroxine Weaken Bones?

Drugs.com

MONDAY, Nov. 25, 2024 -- New research suggests that a thyroid medication often prescribed to older Americans may be linked to a common problem in old age -- bone loss. Levothyroxine is a synthetic hormone often prescribed to treat hypothyroidism.

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Prehistoric hunter-gatherers heard the elks painted on rocks 'talking'

Science Daily: Pharmacology News

Researchers performed acoustic impulse response measurements in front of 37 rock painting site and found that the same vertical rock surfaces that have the painted elks, humans and boats, are also effective sound reflectors.

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A clue to what lies beneath the bland surfaces of Uranus and Neptune

Science Daily: Pharmacology News

When Voyager 2 flew by Uranus and Neptune 40 years ago, astronomers were surprised that it detected no global dipole magnetic fields, like Earth's. The explanation: the ice giants are layered and unmixed, which prevents large scale convection to create a dipole field. But what substances would remain immiscible? A scientist modeled the interiors and found that water-rich and hydrocarbon-rich layers naturally form at extreme pressure and temperature, and they do not mix.

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How Tribal Communities Can Use the Health Hazard Evaluation (HHE) Program

NIOSH Science Blog: Drugs

The final blog post in our series celebrating Native American Heritage Month highlights a free program available to anyone, including American Indian and Alaska Native (AI/AN) communities, employers, and workers. Some may not be aware of this service, though it has been part of the National Institute for Occupational Safety and Helath (NIOSH) around for over 50 years.

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Uranus's swaying moons will help spacecraft seek out hidden oceans

Science Daily: Pharmacology News

A new computer model can be used to detect and measure interior oceans on the ice covered moons of Uranus. The model works by analyzing orbital wobbles that would be visible from a passing spacecraft. The research gives engineers and scientists a slide-rule to help them design NASA's upcoming Uranus Orbiter and Probe mission.

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Ladders to Cures (L2C) Accelerator

Broad Institute

Ladders to Cures (L2C) Accelerator By Maria Nemchuk November 25, 2024 Breadcrumb Home Ladders to Cures (L2C) Accelerator The Ladders to Cures (L2C) Accelerator aims to catalyze progress across the research ecosystem and accelerates advances leading to treatments and cures for patients with rare genetic diseases. We are a community of scientists, physicians, patient advocacy groups, AI/machine learning experts and biopharma veterans working together to gain new mechanistic insights and advance tr

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Focaccia: A Neolithic culinary tradition dating back 9,000 years ago

Science Daily: Pharmacology News

A new study indicates that during the Late Neolithic, between 7000 and 5000 BCE, the fully agricultural communities in the Fertile Crescent region of the Near East, developed a complex culinary tradition that included the baking of large loaves of bread and 'focaccias' with different flavors on special trays known to archaeologists as husking trays.

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The ABCs of Pharma AI

ACTO

“Our ambition is to become the first pharma company powered by artificial intelligence at scale, giving our people tools and technologies that focus on insights and allow them to make better everyday decisions. … We have just scratched the surface as to how we embrace these disruptive technologies to achieve our ambition of transforming the practice of medicine.

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Most energetic cosmic-ray electrons and positrons ever observed

Science Daily: Pharmacology News

Scientists have recently identified electrons and positrons with the highest energies ever recorded on Earth. They provide evidence of cosmic processes emitting colossal amounts of energy, the origins of which are as yet unknown.

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Celebrating National Caregivers Month: Recognizing the Vital Role of Caregivers in Patient Care and Clinical Trials

Antidote

November is National Caregivers Month, a time to celebrate and acknowledge the often-unseen heroes who provide vital support to individuals with chronic illnesses, disabilities, or age-related conditions. Whether they are family members, friends, or professional aides, caregivers offer essential day-to-day assistance that helps their loved ones maintain their health and quality of life.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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New AI tool generates realistic satellite images of future flooding

Science Daily: Pharmacology News

With help from AI, scientists developed a method that generates satellite imagery from the future to depict how a region would look after a potential flooding event.

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Transforming Knowledge Work and Product Development with AI Agents

Perficient: Drug Development

Now more than ever, we’re witnessing a significant shift from simple AI capabilities to action-driven AI Agents that promise to revolutionize how we approach knowledge work, product development, and business processes. Drawing insights from Perficient’s industry experts, we’re constantly exploring Generative AI, the emerging world of agentic frameworks, and their potential to reshape organizational capabilities.

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Novel supernova observations grant astronomers a peek into the cosmic past

Science Daily: Pharmacology News

An international team of researchers has made new observations of an unusual supernova, finding the most metal-poor stellar explosion ever observed.

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Wildfire Smoke Exposure Linked to Dementia Risk

Drugs.com

MONDAY, Nov. 25, 2024 -- People in Southern California with relatively high exposures to wildfire smoke over a decade also had significantly higher risks for dementia, a new study warns. In fact, the fine-particle pollution created by these fires.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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From Imaging to Analysis: 5 Steps for Success with TrialKit PACS

Crucial Data Solutions

When it comes to managing imaging data in clinical trials, researchers find many challenges. Disjointed systems that don’t talk to. The post From Imaging to Analysis: 5 Steps for Success with TrialKit PACS appeared first on Crucial Data Solutions.

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Supreme Court Won't Hear Big Tobacco's Challenge to Cigarette Warning Labels

Drugs.com

MONDAY, Nov. 25, 2024 -- The U.S. Supreme Court on Monday declined to hear a major tobacco company's challenge to a federal law that would mandate graphic images on cigarette packs. Some of the proposed images include a woman with a large lump on.

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Overcoming Issues of Non-Enrolling Sites in Clinical Trials: A Proactive Approach

PPD

Clinical trials are critical for advancing medical research and bringing new treatments to market. However, a significant challenge drug developers face is that of non-enrolling sites. These trial locations, despite being activated, fail to enroll participants, leading to increased costs, delays and potentially compromised trial outcomes. As the clinical trials landscape continues to evolve toward increased complexity, greater efficiency and accelerated development timelines, the ability to mana

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Long COVID Hits the Young Harder Than the Old, Study Finds

Drugs.com

MONDAY, Nov. 25, 2024 -- It might sound counterintuitive, but new research shows that when Long COVID strikes, younger patients appear more prone to severe symptoms than older folks. That's tough on society as a whole, the study's lead author.

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Complex Innovative Trial Designs | Quanticate

Quanticate

Clinical research is ever-changing and increasing in complexity as a result of novel therapies and technologies. In order to address this challenge and maximise the chances of research success, more innovative and creative trial designs are being developed and researched.

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Could a Common Thyroid Medicine Weaken Bones?

Drugs.com

MONDAY, Nov. 25, 2024 -- New research suggests that a thyroid medication often prescribed to older Americans may be linked to a common problem in old age -- bone loss.Levothyroxine is a synthetic hormone often prescribed to treat hypothyroidism.

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Biotech leader champions targeted cancer treatments and diversity

Drug Target Review

In the world of biopharmaceuticals, Dr Catherine Pickering stands out as a pioneering leader. As the CEO of iOnctura, an innovative oncology biopharmaceutical company she co-founded in 2017, Catherine has played a key role in advancing the development of highly targeted small molecules aimed at revolutionising cancer treatment. Her journey in drug R&D and business development has been marked by significant achievements, including leading groundbreaking efforts to treat neglected cancers and

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Reaching Age at Which a Parent Died by Suicide Raises Risk in Adult Child

Drugs.com

MONDAY, Nov. 25, 2024 -- When people whose parents died by suicide reach that same age, their own risk often spikes, Danish researchers warn.Reporting in the journal Suicide and Life-Threatening Behaviors, the researchers looked at data on more.

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Bats' amazing plan B for when they can't hear

Science Daily: Pharmacology News

When bats can't hear, new research finds that these hearing-dependent animals employ a remarkable compensation strategy.

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Illinois Study Finds Steep Rise in Serious Complications of Pregnancy

Drugs.com

MONDAY, Nov. 25, 2024 — Chronic health problems like high blood pressure, gestational diabetes and obesity have fueled a troubling rise in maternal health issues and birth complications in Illinois, a new study finds. "These birth outcomes are w.

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32nd Protein Structure Determination in Industry meeting

Zobio

In person Starting from Sunday, November 10th, the ZoBio team participated in the 32nd Protein Structure Determination in Industry meeting, which was held at the Novotel Paris Centre Tour Eiffel in Paris, France. This year’s meeting was organized jointly by SERVIER and Synchrotron SOLEIL, with support from Hg3 Conferences. The scientific talks focused on the.

Drugs 40
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Yoga Helps Women Deal With the Mental Stress of Cancer

Drugs.com

MONDAY, Nov. 25, 2024 -- A cancer diagnosis can bring overwhelming stress and depression to women, but new research suggests yoga can help ease that emotional toll. “A wellness intervention that integrates yoga and psychological tools may s.

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Drug Channels News Roundup, November 2024: Employers & Their PBMs, Medicaid vs. 340B, U.S. Drug Prices, and Dr. G Shops for Health Plans

Drug Channels

Happy Thanksgiving, everyone! Before you stretch your stomach, stretch your mind with our extra-stuffed helping of food for thought. In this issue: Intriguing data on how employers oversee their PBMs State Medicaid programs carve out PBMs—and get a 340B windfall Are U.S. drug prices really higher than other countries? Plus, Dr. Glaucomflecken gets us ready for the open enrollment season.

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Vaping Immediately Changes Your Blood Flow

Drugs.com

MONDAY, Nov. 25, 2024 -- Even when e-cigarettes are nicotine-free, they have an immediate effect on blood vessels, a new imaging study shows."E-cigarettes have long been marketed as a safer alternative to regular tobacco smoking," said Dr.

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Future-Proof your Benchling Platform: Evolving at the Speed of Science

thought leadership

Science and technology are evolving rapidly, with an explosion in machine learning (ML) and artificial intelligence (AI) creating new possibilities for scientific discovery, operational efficiencies, and the development of novel products and therapies. However, many organizations often struggle to keep pace and leverage these advances due to reliance on legacy technology landscapes.

Science 40