Forbes: Drug Truths

OCTOBER 17, 2023

But keep in mind that it’s going to be a long while before such drugs are actually available.

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Drugs 325

Drug Discovery World

OCTOBER 17, 2023

CARsgen has published evidence of over seven years of disease-free survival in advanced hepatocellular carcinoma (HCC) following treatment with its CAR-GPC3 T cell therapy. Hepatocellular carcinoma is one of the most common malignant tumours, with approximately 780,000 annual incidence cases globally. Recurrence and metastasis are common. For HCC patients with concurrent inferior vena cava tumour thrombus, treatment options are limited and overall prognosis is poor.

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Therapies Hospitals Treatment Virus 163

Chemical Biology and Drug Design

OCTOBER 17, 2023

A hierarchical virtual screening cascade, which combines 3D shape and electrostatics similarity search and molecular docking, aids in the discovery of novel EGFR inhibitors from a large compound library, resulting in 13 EGFR inhibitors under bioassay test. Abstract The epidermal growth factor receptor (EGFR) tyrosine kinase plays an important role in tumor formation and growth by mediating cell growth and other physiological processes.

Treatment 100

Treatment Research 100

Drug Discovery World

OCTOBER 17, 2023

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The buzz with week has been around Phase I trials, with new therapies for lung cancer, geographic atrophy, Parkinson’s, sarcopenia and long Covid demonstrating positive early results or entering clinical trials for the first time.

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Clinical Trials Trials Therapies Drugs 130

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- A new trial demonstrates the power of the diabetes drug Mounjaro in fighting obesity, helping folks who used the medication lose about 60 pounds. "In this study, people who added tirzepatide [Mounjaro] to diet and exercise.

Drugs 116

Drugs Trials 116

Drug Discovery World

OCTOBER 17, 2023

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The buzz with week has been around Phase I trials, with new therapies for lung cancer, geographic atrophy, Parkinson’s, sarcopenia and long Covid demonstrating positive early results or entering clinical trials for the first time.

Clinical Trials 130

Clinical Trials Trials Therapies Drugs 130

Drug Discovery World

OCTOBER 17, 2023

The DDW Turning Science into Business Summit, ‘ Cancer research opportunities and advances ’ will feature experts and thought leaders in cancer research, precision medicine and immunotherapy. Andreas Dreps DDW is delighted to confirm that ICON’s SrVP and Global Head of Science Andreas Dreps and Senior Director Muaiad Kittaneh will present a session on identifying research strategies to get to market faster.

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Marketing Research Clinical Trials Science 130

Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- As kids grow up, their desire to venture out on their own and gain some independence is natural. And a new national poll suggests that most parents say they’re fine with that. The problem? The poll highlights a.

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Perficient: Drug Development

OCTOBER 17, 2023

Recently, the Cultural Connections ERG held its first “Cultivating Career Growth” event highlighting the experiences of Malvika Malviya, Lead Technical Consultant in India; Ron Jones, Director in the United States; Miroslav Maric, Manager in Serbia and Margarita Hoyos, Lead Software Developer in Colombia, who are part of Perficient’s global community.

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Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- High-risk surgeries are more deadly for Black and Hispanic Americans than for their white counterparts, new research reveals. The study, of more than 1 million procedures performed in U.S.

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Hospitals Research 105

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Clinical Trials

Broad Institute

OCTOBER 17, 2023

#WhyIScience Q&A: A research scientist uses mass spectrometry to discover how metabolites affect human health By Corie Lok October 17, 2023 Breadcrumb Home #WhyIScience Q&A: A research scientist uses mass spectrometry to discover how metabolites affect human health Amy Deik talks about her unique career path that led her to the Broad’s Metabolomics Platform.

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Research Small Molecule Science Research Laboratories 98

Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- Scientists have discovered two genes that may trigger Raynaud’s phenomenon, a condition that can cause fingers and toes to go cold and numb because of the constriction of tiny blood vessels under the skin. “We.

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Drug Target Review

OCTOBER 17, 2023

Scientists at the Biozentrum, University of Basel, have found a key driver of metabolic rewiring in liver cancer cells. The liver is an essential organ that has a variety of crucial functions in the body, including metabolising nutrients, storing energy, regulating blood sugar levels and detoxifying and removing harmful substances. Liver cancer is one of the most dangerous cancers, with its main causes being obesity, excessive alcohol consumption and hepatitis C infection.

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Regulations Therapies Treatment Disease 98

Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- The drugstore chain Rite Aid has filed for Chapter 11 bankruptcy, due largely to competition and thousands of lawsuits for its role in allegedly filling unlawful opioid prescriptions. The company filed a notice Thursday.

Pharmacy 105

Pharmacy 105

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Clinical Trials

On Medicine

OCTOBER 17, 2023

Discrimination based on one’s group membership can be a significant source of stress. When it occurs frequently, it can have a long-term impact on both physical and mental health, as per the Minority Stress Model. Unfortunately, a recent poll reveals that 45% of Romanian LGBT+ respondents have experienced discrimination in at least one aspect of life within the past year.

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Testimonials Trials Therapies Clinical Trials 95

Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- A liver transplant can give people a new lease on life, but at the cost of lifelong immune-suppressing medication and its risks. Now an innovative approach to reduce, or possibly eliminate, certain patients' reliance on.

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Science Daily: Pharmacology News

OCTOBER 17, 2023

Scientists have announced the results of an unprecedented collaboration to search for the source of the largest ever seismic event recorded on Mars. The study rules out a meteorite impact, suggesting instead that the quake was the result of enormous tectonic forces within Mars' crust.

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Drugs.com

OCTOBER 17, 2023

SATURDAY, Oct. 14, 2023 -- While the hot, dry summer may have offered a break to people with some environmental allergies, that reprieve could be over. Ragweed and mold are in the air this fall. “This summer was good news for people who are.

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Science Daily: Pharmacology News

OCTOBER 17, 2023

The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location of imperfect complementary sequences. Fluorescent markers bound to one of the matching DNA strands make the duplex visible, and fluorescence intensity increases with increasing duplex stability.

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DNA Research 82

BioPharma Drive: Drug Pricing

OCTOBER 17, 2023

The Danish drugmaker's innovation hub in Boston has teamed up with the Broad Institute, Mass General Brigham, Harvard and Yale, expanding its research into cardiometabolic diseases.

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Disease Drugs Research 76

Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- Pickleball has become wildly popular, but that may be fueling a rise in pickleball-related injuries. “It’s quickly becoming a sport of choice for adults over the age of 50,” said Dr. Brian Cole, an.

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Science Daily: Pharmacology News

OCTOBER 17, 2023

A new study looked at 926 polygenic risk scores for 310 diseases. It found that, on average, only 11% of individuals who develop disease are identified, while at the same time 5% of people who do not develop the disease test positive. Unaffected people usually outnumber those affected which results in far more false than true positive predictions.

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Disease 76

Drug Channels

OCTOBER 17, 2023

In case you haven’t noticed, private equity firms have displaced hospitals and health systems as the major acquirers of community oncology practices. These financial firms have assembled significant oncology practice management companies that are primed for purchase by drug channel participants. Below, I review recent M&A trends and then examine the strategic objectives behind the acquisition of private-equity-backed OneOncology by AmerisourceBergen (Cencora) and another financial buyer.

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Pharmaceuticals Hospitals Drugs 97

Science Daily: Pharmacology News

OCTOBER 17, 2023

Researchers say they have found 'definitive' archaeological evidence that seaweeds and other local freshwater plants were eaten in the mesolithic, through the Neolithic transition to farming and into the Early Middle Ages, suggesting that these resources, now rarely eaten in Europe, only became marginal much more recently.

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Research 71

BioPharma Drive: Drug Pricing

OCTOBER 17, 2023

One month after Roche’s Genentech inked a similar deal, the Swiss pharma is now paying $50 million to work with Monte Rosa on molecular glue medicines for cancer and neurological diseases.

Disease 62

Disease 62

Drug Patent Watch

OCTOBER 17, 2023

Annual Drug Patent Expirations for HETLIOZ+LQ Hetlioz Lq is a drug marketed by Vanda Pharms Inc and is included in one NDA. It is available from one supplier. There are… The post New patent for Vanda Pharms drug HETLIOZ LQ appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

BioPharma Drive: Drug Pricing

OCTOBER 17, 2023

The Merck drug leads competitors Opdivo and Imfinzi into a new immunotherapy setting, which aims to improve outcomes following the surgical removal of tumors.

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Drugs 67

Drug Patent Watch

OCTOBER 17, 2023

Annual Drug Patent Expirations for HETLIOZ Hetlioz is a drug marketed by Vanda Pharms Inc and is included in two NDAs. It is available from one supplier. There are twenty-two… The post New patent for Vanda Pharms drug HETLIOZ appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

BioPharma Drive: Drug Pricing

OCTOBER 17, 2023

Tuesday’s earnings were the first since J&J officially split off its consumer drug business, now the publicly traded company Kenvue.

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Drugs 70

Drug Patent Watch

OCTOBER 17, 2023

Annual Drug Patent Expirations for FINTEPLA Fintepla is a drug marketed by Ucb Inc and is included in one NDA. It is available from one supplier. There are eleven patents… The post New patent for Ucb Inc drug FINTEPLA appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- The vast majority of women know a lump in their breast likely signals the presence of cancer, a new survey finds, but that's not the only sign of the disease. “Screening mammography is our No. 1 defense in detecting.

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Disease 59

SCIENMAG: Medicine & Health

OCTOBER 17, 2023

Aspergillus fumigatus is the major airborne fungus present indoors and outdoors that causes various diseases, the severity of which are dependent on an individual’s immune status.

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Research Science Disease 52

Drugs.com

OCTOBER 17, 2023

MONDAY, Oct. 16, 2023 -- Actress Suzanne Somers died “peacefully at home” Sunday morning after a return of breast cancer, her publicist announced. Best known for her roles on "Three's Company" and "Step by Step," Somers was.

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SCIENMAG: Medicine & Health

OCTOBER 17, 2023

OCTOBER 17, 2023, NEW YORK – It is with great pleasure that Ludwig Cancer Research announces its launch of the Ludwig Leadership Fellows Program. Credit: Ludwig Cancer Research OCTOBER 17, 2023, NEW YORK – It is with great pleasure that Ludwig Cancer Research announces its launch of the Ludwig Leadership Fellows Program.

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Research 52