Companies Seek To Increase Life Span By A Decade Or More
Forbes: Drug Truths
OCTOBER 17, 2023
But keep in mind that it’s going to be a long while before such drugs are actually available.
Forbes: Drug Truths
OCTOBER 17, 2023
But keep in mind that it’s going to be a long while before such drugs are actually available.
Drug Discovery World
OCTOBER 17, 2023
CARsgen has published evidence of over seven years of disease-free survival in advanced hepatocellular carcinoma (HCC) following treatment with its CAR-GPC3 T cell therapy. Hepatocellular carcinoma is one of the most common malignant tumours, with approximately 780,000 annual incidence cases globally. Recurrence and metastasis are common. For HCC patients with concurrent inferior vena cava tumour thrombus, treatment options are limited and overall prognosis is poor.
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Chemical Biology and Drug Design
OCTOBER 17, 2023
A hierarchical virtual screening cascade, which combines 3D shape and electrostatics similarity search and molecular docking, aids in the discovery of novel EGFR inhibitors from a large compound library, resulting in 13 EGFR inhibitors under bioassay test. Abstract The epidermal growth factor receptor (EGFR) tyrosine kinase plays an important role in tumor formation and growth by mediating cell growth and other physiological processes.
Drug Discovery World
OCTOBER 17, 2023
The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The buzz with week has been around Phase I trials, with new therapies for lung cancer, geographic atrophy, Parkinson’s, sarcopenia and long Covid demonstrating positive early results or entering clinical trials for the first time.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- A new trial demonstrates the power of the diabetes drug Mounjaro in fighting obesity, helping folks who used the medication lose about 60 pounds. "In this study, people who added tirzepatide [Mounjaro] to diet and exercise.
Drug Discovery World
OCTOBER 17, 2023
The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The buzz with week has been around Phase I trials, with new therapies for lung cancer, geographic atrophy, Parkinson’s, sarcopenia and long Covid demonstrating positive early results or entering clinical trials for the first time.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Discovery World
OCTOBER 17, 2023
The DDW Turning Science into Business Summit, ‘ Cancer research opportunities and advances ’ will feature experts and thought leaders in cancer research, precision medicine and immunotherapy. Andreas Dreps DDW is delighted to confirm that ICON’s SrVP and Global Head of Science Andreas Dreps and Senior Director Muaiad Kittaneh will present a session on identifying research strategies to get to market faster.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- As kids grow up, their desire to venture out on their own and gain some independence is natural. And a new national poll suggests that most parents say they’re fine with that. The problem? The poll highlights a.
Perficient: Drug Development
OCTOBER 17, 2023
Recently, the Cultural Connections ERG held its first “Cultivating Career Growth” event highlighting the experiences of Malvika Malviya, Lead Technical Consultant in India; Ron Jones, Director in the United States; Miroslav Maric, Manager in Serbia and Margarita Hoyos, Lead Software Developer in Colombia, who are part of Perficient’s global community.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- High-risk surgeries are more deadly for Black and Hispanic Americans than for their white counterparts, new research reveals. The study, of more than 1 million procedures performed in U.S.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Broad Institute
OCTOBER 17, 2023
#WhyIScience Q&A: A research scientist uses mass spectrometry to discover how metabolites affect human health By Corie Lok October 17, 2023 Breadcrumb Home #WhyIScience Q&A: A research scientist uses mass spectrometry to discover how metabolites affect human health Amy Deik talks about her unique career path that led her to the Broad’s Metabolomics Platform.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- Scientists have discovered two genes that may trigger Raynaud’s phenomenon, a condition that can cause fingers and toes to go cold and numb because of the constriction of tiny blood vessels under the skin. “We.
Drug Target Review
OCTOBER 17, 2023
Scientists at the Biozentrum, University of Basel, have found a key driver of metabolic rewiring in liver cancer cells. The liver is an essential organ that has a variety of crucial functions in the body, including metabolising nutrients, storing energy, regulating blood sugar levels and detoxifying and removing harmful substances. Liver cancer is one of the most dangerous cancers, with its main causes being obesity, excessive alcohol consumption and hepatitis C infection.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- The drugstore chain Rite Aid has filed for Chapter 11 bankruptcy, due largely to competition and thousands of lawsuits for its role in allegedly filling unlawful opioid prescriptions. The company filed a notice Thursday.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
On Medicine
OCTOBER 17, 2023
Discrimination based on one’s group membership can be a significant source of stress. When it occurs frequently, it can have a long-term impact on both physical and mental health, as per the Minority Stress Model. Unfortunately, a recent poll reveals that 45% of Romanian LGBT+ respondents have experienced discrimination in at least one aspect of life within the past year.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- A liver transplant can give people a new lease on life, but at the cost of lifelong immune-suppressing medication and its risks. Now an innovative approach to reduce, or possibly eliminate, certain patients' reliance on.
Science Daily: Pharmacology News
OCTOBER 17, 2023
Scientists have announced the results of an unprecedented collaboration to search for the source of the largest ever seismic event recorded on Mars. The study rules out a meteorite impact, suggesting instead that the quake was the result of enormous tectonic forces within Mars' crust.
Drugs.com
OCTOBER 17, 2023
SATURDAY, Oct. 14, 2023 -- While the hot, dry summer may have offered a break to people with some environmental allergies, that reprieve could be over. Ragweed and mold are in the air this fall. “This summer was good news for people who are.
Science Daily: Pharmacology News
OCTOBER 17, 2023
The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location of imperfect complementary sequences. Fluorescent markers bound to one of the matching DNA strands make the duplex visible, and fluorescence intensity increases with increasing duplex stability.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2023
The Danish drugmaker's innovation hub in Boston has teamed up with the Broad Institute, Mass General Brigham, Harvard and Yale, expanding its research into cardiometabolic diseases.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- Pickleball has become wildly popular, but that may be fueling a rise in pickleball-related injuries. “It’s quickly becoming a sport of choice for adults over the age of 50,” said Dr. Brian Cole, an.
Science Daily: Pharmacology News
OCTOBER 17, 2023
A new study looked at 926 polygenic risk scores for 310 diseases. It found that, on average, only 11% of individuals who develop disease are identified, while at the same time 5% of people who do not develop the disease test positive. Unaffected people usually outnumber those affected which results in far more false than true positive predictions.
Drug Channels
OCTOBER 17, 2023
In case you haven’t noticed, private equity firms have displaced hospitals and health systems as the major acquirers of community oncology practices. These financial firms have assembled significant oncology practice management companies that are primed for purchase by drug channel participants. Below, I review recent M&A trends and then examine the strategic objectives behind the acquisition of private-equity-backed OneOncology by AmerisourceBergen (Cencora) and another financial buyer.
Science Daily: Pharmacology News
OCTOBER 17, 2023
Researchers say they have found 'definitive' archaeological evidence that seaweeds and other local freshwater plants were eaten in the mesolithic, through the Neolithic transition to farming and into the Early Middle Ages, suggesting that these resources, now rarely eaten in Europe, only became marginal much more recently.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2023
One month after Roche’s Genentech inked a similar deal, the Swiss pharma is now paying $50 million to work with Monte Rosa on molecular glue medicines for cancer and neurological diseases.
Drug Patent Watch
OCTOBER 17, 2023
Annual Drug Patent Expirations for HETLIOZ+LQ Hetlioz Lq is a drug marketed by Vanda Pharms Inc and is included in one NDA. It is available from one supplier. There are… The post New patent for Vanda Pharms drug HETLIOZ LQ appeared first on DrugPatentWatch - Make Better Decisions.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2023
The Merck drug leads competitors Opdivo and Imfinzi into a new immunotherapy setting, which aims to improve outcomes following the surgical removal of tumors.
Drug Patent Watch
OCTOBER 17, 2023
Annual Drug Patent Expirations for HETLIOZ Hetlioz is a drug marketed by Vanda Pharms Inc and is included in two NDAs. It is available from one supplier. There are twenty-two… The post New patent for Vanda Pharms drug HETLIOZ appeared first on DrugPatentWatch - Make Better Decisions.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2023
Tuesday’s earnings were the first since J&J officially split off its consumer drug business, now the publicly traded company Kenvue.
Drug Patent Watch
OCTOBER 17, 2023
Annual Drug Patent Expirations for FINTEPLA Fintepla is a drug marketed by Ucb Inc and is included in one NDA. It is available from one supplier. There are eleven patents… The post New patent for Ucb Inc drug FINTEPLA appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- The vast majority of women know a lump in their breast likely signals the presence of cancer, a new survey finds, but that's not the only sign of the disease. “Screening mammography is our No. 1 defense in detecting.
SCIENMAG: Medicine & Health
OCTOBER 17, 2023
Aspergillus fumigatus is the major airborne fungus present indoors and outdoors that causes various diseases, the severity of which are dependent on an individual’s immune status.
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- Actress Suzanne Somers died “peacefully at home” Sunday morning after a return of breast cancer, her publicist announced. Best known for her roles on "Three's Company" and "Step by Step," Somers was.
SCIENMAG: Medicine & Health
OCTOBER 17, 2023
OCTOBER 17, 2023, NEW YORK – It is with great pleasure that Ludwig Cancer Research announces its launch of the Ludwig Leadership Fellows Program. Credit: Ludwig Cancer Research OCTOBER 17, 2023, NEW YORK – It is with great pleasure that Ludwig Cancer Research announces its launch of the Ludwig Leadership Fellows Program.
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