Science Daily: Pharmacology News
AUGUST 20, 2024
A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.
ASPET
AUGUST 20, 2024
Hepatic ischemia/reperfusion (I/R) damage is one of the most common side effects of liver surgery. This pathophysiological process may lead to excessive hepatic damage. Aloperine is an active ingredient isolated from Sophora alopecuroides Linn and has a variety of therapeutic effects, including organ protection. However, the hepatoprotective effect of aloperine against hepatic I/R damage has not yet been determined.
Science Daily: Pharmacology News
AUGUST 20, 2024
Researchers suggest a new designation of the humpback whales they study: tool wielders. Researchers have known that humpback whales create "bubble-nets" to hunt, but they have learned that the animals don't just create the bubble-nets; they manipulate this unique tool in a variety of ways to maximize their food intake in Alaskan feeding grounds.
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- Tirzepatide, the blockbuster GLP-1 medicine known as Mounjaro for diabetes and Zepbound for weight loss, cut the odds that an obese, prediabetic person will develop diabetes by 94%, a new trial shows. The three-year-long.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Fierce BioTech
AUGUST 20, 2024
Alzheimer’s disease research and drug development is evolving at a rapid pace. Decades of research has led to the approval of the first disease-modifying drugs and new pathological discoveries.
Science Daily: Pharmacology News
AUGUST 20, 2024
Meat consumption, particularly consumption of processed meat and unprocessed red meat, is associated with a higher type 2 diabetes risk, an analysis of data from 1.97 million participants.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
AUGUST 20, 2024
Researchers have succeeded in something that has been pursued since the 1970s: explaining the X-ray radiation from the black hole surroundings. The radiation originates from the combined effect of the chaotic movements of magnetic fields and turbulent plasma gas.
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- The overdose-reversing drug naloxone can help save the lives of people whose hearts have stopped due to an opioid OD, a new study shows.Naloxone rapidly reverses opioid ODs by blocking the ability of opioids to bind with.
BioPharma Drive: Drug Pricing
AUGUST 20, 2024
Treatment with the GLP-1 drug, which Lilly sells as Mounjaro and Zepbound, lowered the risk of Type 2 diabetes progression by 94% versus placebo.
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- Toxin from one of the most venomous animals on the planet – a deadly sea snail – could help researchers figure out new ways to treat diabetes and other hormone disorders, a new study suggests.A toxin in the venom of the geo.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
AUGUST 20, 2024
A new study shows how the mismatch between where fossils are preserved and where humans likely lived may influence our understanding of early human evolution.
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- Tiny turtles are the cause of a outbreak of 51 cases of salmonella in 21 states, the U.S. Centers for Disease Control and Prevention announced Friday.In almost half of cases, the illness has been so severe as to require.
Science Daily: Pharmacology News
AUGUST 20, 2024
Our understanding of Venus' water history and the potential that it was once habitable in the past is being challenged by recent observations.
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- An insect-borne virus that can cause birth defects and deaths has prompted warnings from the United States for travelers headed to locales in South America and the Caribbean.Oropouche virus has caused two deaths and five.
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addgene Blog
AUGUST 20, 2024
Now that you know how to read flow plots and have designed your first flow panel , you’ll load your samples into the cytometer and see one of two results for your antibody of interest: two clear populations or a huge smear across your FSH vs reporter plot. In this post, I’ll walk you through how to interpret the antibody readout on a flow plot.
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- One of the most abundant fatty acids in the body -- and a key ingredient in the Mediterranean diet -- could be a safe, easy and natural cure for bacterial vaginosis, a new lab study suggests.Oleic acid can inhibit the.
DrugBank
AUGUST 20, 2024
The world of drug discovery is in a state of transformation, with advancements in biotechnology opening doors to new possibilities for targeting previously "undruggable" disease mechanisms. If you're a pharmaceutical researcher or drug developer, understanding these breakthroughs is critical to staying at the forefront of innovation. Our new eBook, Unlocking Undruggable Targets: Biotechnology’s Role in Expanding Drug Discovery , is your comprehensive guide to navigating this
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- Updated shots you could use this fall to shield against COVID-19 infection may receive approval this week.Two sources familiar with the issue told CNN that updated mRNA vaccines from Moderna and Pfizer that target a.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Broad Institute
AUGUST 20, 2024
#WhyIScience Q&A: A systems biologist develops computational tools to bring scale to cell experiments By Allessandra DiCorato August 20, 2024 Breadcrumb Home #WhyIScience Q&A: A systems biologist develops computational tools to bring scale to cell experiments Yue Qin talks about the unique advantages of interdisciplinary science that bridges biology and computer science.
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- Final government data finds the number of U.S. births falling by 2% last year compared to 2022, continuing a decades-long decline.Overall, annual U.S. birth numbers have fallen by 17% since peaking in 2007, according to.
BioPharma Drive: Drug Pricing
AUGUST 20, 2024
Approval of Rybrevant and Lazcluze was supported by results from a study that compared the regimen to AstraZeneca’s widely used drug Tagrisso.
Drugs.com
AUGUST 20, 2024
TUESDAY, Aug. 20, 2024 -- Some seniors with end-stage kidney failure who are too sick for a transplant should probably skip dialysis because the health trade-offs aren't worth it, a new study says.Seniors who started dialysis immediately after.
Perficient: Drug Development
AUGUST 20, 2024
Let’s test a button color! I hear this alot with clients. While that can sometimes be a valid beginner AB test, your web designer and UX specialist likely chose the current color based on years of sound research. That likely makes it an unfavorable candidate for a good test. So, what makes a good test then? What’s the secret sauce? A good test has these attributes: It tests a component/page that influences conversion.
Science Daily: Pharmacology News
AUGUST 20, 2024
High-resolution images show large spots on the surface of Polaris.
BioPharma Drive: Drug Pricing
AUGUST 20, 2024
In addition to new stock offerings, this week saw Merck license an antibody drug conjugate and BARDA further work trying to innovate remote clinical trials.
KIF1A
AUGUST 20, 2024
“Pauline is the joy of the family. She was the angel who came to bring us even closer together.” A message from Pauline’s family in Brazil: Pauline was born on 09/27/2023, with a smooth pregnancy, but in the last 2 months, observing the ultrasounds exams, it was identified that the measurements of the long-bones of the arms and legs were much lower than normal, but the doctor told us to wait until the birth to determine if she had or not dwarfism.
Perficient: Drug Development
AUGUST 20, 2024
In the realm of modern business operations, efficient inventory management is paramount. Companies must keep track of a plethora of items, ensuring that they are properly categorized, tracked, and managed. Oracle Product Data Hub (PDH) Cloud and Oracle Inventory Management Cloud are two powerful tools that work in tandem to achieve these goals. A critical component of this system is item classification, which significantly impacts inventory management.
KIF1A
AUGUST 20, 2024
While I think most of our readers will understand the enormity of today’s title, it’s worth stating explicitly that Susannah Rosen is on a huge journey. We often call members of our community Superheroes, but internally I default to another term Luke Rosen and advocates use often: Pioneers. In fact the Yellow Brick Road Project, representing patients with HNRNPH2 mutations, dubbed this the Year of the Pioneer, a banner we’re happy to spread: It reflects the unknown course of na
Perficient: Drug Development
AUGUST 20, 2024
The rapid advancement of artificial intelligence (AI) has led to the development of foundational models that form the bedrock of numerous AI applications. AWS Bedrock is Amazon Web Services’ comprehensive solution that leverages these models to provide robust AI and machine learning (ML) capabilities. This blog delves into the essentials of AI foundational models in AWS Bedrock, highlighting their significance and applications.
Drug Patent Watch
AUGUST 20, 2024
Digital twins are revolutionizing the pharmaceutical and biopharmaceutical industries by integrating physical plants, data collection, data analysis, and system control.
Drug Channels
AUGUST 20, 2024
Another news-laden summer is ending. Time to pack away your bathing suit, send the kids back to school, and cherish these curated curiosities that I combed from the Jersey shore: Some uncomfortable realities of the Inflation Reduction Act’s (IRA’s) first set of 10 prices Amazon goes after retail pharmacies with an amusing lack of self-awareness A health system-backed start-up pharmacy benefit manager (PBM) will somehow deliver massive drug costs savings An intriguing solution for fixing the 340B
BioPharma Drive: Drug Pricing
AUGUST 20, 2024
J&J has agreed to pay $600 million upfront for the private company as it works to expand its portfolio of cardiovascular devices.
Sygnature Discovery
AUGUST 20, 2024
World-leading contract research organization Sygnature Discovery has announced a major new addition to its leadership team, with the high-profile appointment of industry veteran Jade Dagher as General Manager, Canada. Jade Dagher – General Manager, Canada Jade is a “big hitter” in the sector and has over 35 years of experience in pharmaceuticals, including 25 years with Global pharma giant Merck.
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