Tue.Sep 10, 2024

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Methane emissions are rising faster than ever

Science Daily: Pharmacology News

Methane concentrations in Earth's atmosphere increased at record speed over the past five years. At least two-thirds of annual methane emissions now come from human activities, including fossil fuel use, agriculture, and landfills and other waste.

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Chronic Steroid Use Could Raise Diabetes Risk

Drugs.com

TUESDAY, Sept. 10, 2024 -- Taking steroids more than doubles a person’s risk of developing type 2 diabetes, a new study warns.Patients taking steroid pills, injections or infusions are 2.6 times more likely to develop diabetes than those not on s.

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Like father, like daughter

Science Daily: Pharmacology News

When they become fathers, men who have an unhealthy, high-cholesterol diet can cause increased risk of cardiovascular disease, or CVD, in their daughters, a mouse study has found.

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Could Sulthiame, a Pill Approved in Europe for Epilepsy, Help Ease Sleep Apnea?

Drugs.com

TUESDAY, Sept. 10, 2024 -- A European epilepsy drug could be an effective treatment for sleep apnea, a new study suggests. Patients who took sulthiame had few pauses in their breathing while asleep, as well as higher levels of blood oxygen.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Strongest battery paves way for light, energy-efficient vehicles

Science Daily: Pharmacology News

When cars, planes, ships or computers are built from a material that functions as both a battery and a load-bearing structure, the weight and energy consumption are radically reduced. A research group is now presenting an advance in so-called massless energy storage -- a structural battery that could halve the weight of a laptop, make the mobile phone as thin as a credit card or increase the driving range of an electric car by up to 70 percent on a single charge.

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Libido Can Drop After Menopause, But This Therapy Can Help

Drugs.com

TUESDAY, Sept. 10, 2024 -- A form of psychotherapy can help women whose libidos have suffered as they go through menopause, a new study finds.Cognitive behavioral therapy significantly improved sexual desire and satisfaction in a small group of.

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Pandemic Isolation May Have Caused Rapid Brain Aging in Teen Girls

Drugs.com

TUESDAY, Sept. 10, 2024 -- New research uncovers a possible reason why teenaged girls struggled so mightily with their mental health during the pandemic: Scans showed their brains aged far faster than expected during that stressful time, even.

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Antibody Validation for Flow Cytometry

addgene Blog

Antibody validation is to confirm (or refute) that the antibody is selectively detecting the target-of-interest in your assay and sample-of-interest. The approaches available broadly map onto the five pillars of antibody validation (see: Uhlen et al., 2016 ). In this post, we will describe the approaches that can be used to determine selectivity of an antibody for flow cytometry experiments.

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Exercising Can Help You Have Healthier Belly Fat

Drugs.com

TUESDAY, Sept. 10, 2024 -- Annoyed that you still have a bit of tummy even though you work out all the time?Exercise actually is helping you develop healthier belly fat tissue, a new study says.That means that even if you don’t obtain six-pack abs.

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NTRC Marks 20 Years of Studying Nanotoxicology: Highlights from the Toxicology and Internal Dose Team

NIOSH Science Blog: Drugs

Where It Started As the Nanotechnology Research Center (NTRC) marks its 20th anniversary, we reflect on our achievements in the field of nanotoxicology. Within the National Institute for Occupational Safety and Health (NIOSH), one NTRC goal is to understand possible harm from nanomaterials in workplaces. Our work has its origins in earlier research.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Could a Pill Help Ease Sleep Apnea?

Drugs.com

TUESDAY, Sept. 10, 2024 -- A European epilepsy drug could be an effective treatment for sleep apnea, a new study suggests.Patients who took sulthiame had few pauses in their breathing while asleep, as well as higher levels of blood oxygen.

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Investors are waking up to Centessa’s sleepiness drug

BioPharma Drive: Drug Pricing

A small, early study produced what one analyst called “highly compelling” results that lifted the company’s shares by as much as 15% Tuesday.

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Voice Changes Warn of COPD Flare-Ups

Drugs.com

TUESDAY, Sept. 10, 2024 -- A flare-up in COPD can be predicted through changes in a person’s voice, a new study claims.Patients’ voices become higher-pitched, more breathy or hoarse when a flare-up is imminent, researchers found.Using those cues, re.

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Rapid delivery of toxicological material

Drug Target Review

The current landscape of protein drug development is characterised by accelerated timelines where new drugs are approved in months rather than years. To achieve an aggressive timeline from DNA to investigational new drug (IND) application, drug developers have strengthened collaborations with contract development & manufacturing organisations (CDMOs) to expedite drug development.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Apple Will Sell Air Pods With Hearing Aids Built In

Drugs.com

TUESDAY, Sept. 10, 2024 -- The latest AirPods from Apple will come with built-in hearing aids, the company announced Monday.Designed as an over-the-counter hearing aid feature for those with mild to moderate hearing loss, users take hearing tests.

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House backs bill restricting China role in US biotech

BioPharma Drive: Drug Pricing

The Biosecure Act, which limits contracts with WuXi AppTec, WuXi Biologics and three other companies, still needs Senate support to advance.

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Zelatriazin

New Drug Approvals

Zelatriazin, C 18 H 15 F 3 N 4 O 3 , 392.3 g/mol 1929519-13-0 NBI-1065846 or TAK-041 Phase 2 (S)-2-(4-oxobenzo[d][1,2,3]triazin-3(4H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide Zelatriazin ( NBI-1065846 or TAK-041 ) is a small-molecule agonist of GPR139. It was developed for schizophrenia and anhedonia in depression but trials were unsuccessful and its development was discontinued in 2023. [1] [2] [3] [4] [5] [6] [7] SCHEME SYN WO2016081736 [link] Example 2: (S)-2-(4-oxobenzo[d][l,2,3]

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Custom Weather Forecast Model Using ML Net

Perficient: Drug Development

Nowadays, AI is a crucial field with various frameworks like ML.NET that can be used to build amazing applications using pre-built models from cloud providers. It’s important to learn how these services work behind the scenes, how to create custom models, and understand how your application can interact with AI frameworks beyond just cloud providers or the source of the AI services.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Vorasidenib

New Drug Approvals

Vorasidenib 6-(6-chloropyridin-2-yl)-N2,N4-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine CAS 1644545-52-7 , C 14 H 13 ClF 6 N 6 , 414.74 FDA APPROVED, 8/6/2024, Voranigo , To treat Grade 2 astrocytoma or oligodendroglioma UNII 789Q85GA8P AG 881 AG-881 AG881 Ingredient UNII CAS InChI Key Vorasidenib citrate X478M962XG 2316810-02-1 YOUTVRFNJAAFNS-DLVAHKFUSA-N Vorasidenib citrate anhydrous W4XG3EQK7B 2316810-00-9 OCEHQNOYRLHJCI-WPRTUUMNSA-N Vorasidenib , sold under the brand name

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New data add to doubts about AstraZeneca, Daiichi’s Enhertu successor

BioPharma Drive: Drug Pricing

The partners’ ADC didn’t significantly extend survival in lung cancer patients who were expected to benefit the most from treatment in a Phase 3 trial.

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Women’s Health: Experts Talk Economics, Education & Equality

Fierce BioTech

Women’s Health: Experts Talk Economics, Education & Equality dwunderlin Tue, 09/10/2024 - 12:32 Wed, 10/16/2024 - 11:00 Resource Type Webinar Dorothy Gemmell Aditi Goenka Promotion Start Wed, 09/18/2024 - 13:45 Duration 60 Minutes While just over 50% of people living in the U.S. identify as women, they have an outsized impact on healthcare decisions and spending, influencing 80% of the roughly $4 trillion healthcare system.

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Deuruxolitinib

New Drug Approvals

Deuruxolitinib C 17 H 18 N 6 , 314.422 Fda approved Leqselvi , 7/25/2024, To treat severe alopecia areata C-21543, CTP 543, CTP-543, CTP543 (3r)-3-(2,2,3,3,4,4,5,5-d8)cyclopentyl-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)propanenitrile 1h-pyrazole-1-propanenitrile,beta.-(cyclopentyl-2,2,3,3,4,4,5,5-d8)-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (.beta.r)-D8-ruxolitinib Ingredient UNII CAS InChI Key Deuruxolitinib phosphate 8VJ43S4LCM 2147706-60-1 JFMWPOCYMYGEDM-NTVOUFPTSA-N unii 0CA0VSF9

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U.S. Suicide Rates Rise in Less Affluent Areas

Drugs.com

TUESDAY, Sept. 10, 2024 -- An analysis of where suicides are occurring in the United States shows that, tragically, location matters. People living in poorer areas with fewer resources are significantly more likely to fall victim to suicide versus.

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Top Dreamforce 2024 Sessions with Kristen Quick: Transforming Healthcare and Life Sciences

Perficient: Drug Development

The healthcare and life sciences industries are rapidly evolving, fueled by the demand for innovation, efficiency, and patient-centric care. Emerging technologies like AI and cloud platforms are reshaping how healthcare organizations operate. Kristen Quick , Director at Perficient and HLS Industry Lead within the Salesforce practice, brings 15 years of expertise to guide transformative initiatives.

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Falling for Financial Scams Could Be Early Alzheimer's Sign

Drugs.com

TUESDAY, Sept. 10, 2024 -- Brain changes that signal Alzheimer's disease even before symptoms appear are linked to an increased vulnerability to financial scams, new research shows.“Assessing financial vulnerability in older adults could help i.

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Computational Complexity Theory

Perficient: Drug Development

Computational complexity studies the efficiency of algorithms. It helps classify the algorithm in terms of time and space to identify the amount of computing resources needed to solve a problem. The Big Ω, and Big θ notations are used to describe the asymptotic behavior of an algorithm as a function of the input size. In computer science, computational complexity theory is fundamental to understanding the limits of how efficiently an algorithm can be computed.

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Asthma Risk Doubles in People With Diabetes

Drugs.com

TUESDAY, Sept. 10, 2024 -- People with type 2 diabetes are nearly twice as likely to develop asthma, a new review has concluded.Type 2 diabetics are 83% more likely to develop asthma, compared to those without diabetes, researchers found.The.

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Unique Solutions for Drug Discovery and Development

Fierce BioTech

Unique Solutions for Drug Discovery and Development Today's drug development teams need solutions that push discovery, de-risk development, and trim timelines. But each project comes with a unique set of challenges. Cell Signaling Technology (CST) is a company founded and led by active research scientists, so our approach to helping you solve those challenges is different.

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Asthma Could Raise Miscarriage, Infertility Risks for Women: Study

Drugs.com

TUESDAY, Sept. 10, 2024 -- Having asthma appears linked to raised odds for miscarriage and troubles with fertility among women, new Danish research shows.“We found that women fulfilling the definition of asthma had a higher rate of fetal loss and a.

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Drug Channels Leadership Forum: Full Agenda Now Available (Spoiler: It’s Awesome!)

Drug Channels

I am pleased to announce the full agenda for the inaugural Drug Channels Leadership Forum , which will be held from March 17 to 19, 2025, at the Turnberry Resort and Spa in Miami. Everyone here at Drug Channels Institute (DCI) is excited to bring this novel event to the drug channels community. I personally assembled the agenda. As you can see, it’s filled with senior industry executives who will participate in fireside chats with me as well as topical panel discussions moderated by a diverse se

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Bain closes $3B biotech fund amid flurry of startup buyouts

BioPharma Drive: Drug Pricing

The fund is Bain’s fourth and follows several recent acquisitions of some of its portfolio companies, among them Jnana Therapeutics and EyeBio.

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Health Economics and Outcomes Research (HEOR) Programming

Quanticate

Discover what Health Economics and Outcomes Research (HEOR) is and how it’s applied in programming to analyse healthcare data and improve patient outcomes.

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Preserve Cash and Accelerate Your Growth: Strategic Equipment Lease Financing Options

Fierce BioTech

Preserve Cash and Accelerate Your Growth: Strategic Equipment Lease Financing Options Download now to learn how strategic equipment lease financing can help biotech and life sciences companies optimize cash flow, access essential technology without large upfront costs, and preserve equity while driving growth. Discover how to secure vital resources to thrive in a competitive market. dfarris Tue, 09/10/2024 - 14:22 By downloading this whitepaper, you'll learn how strategic equipment lease financi

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