Tue.Apr 16, 2024

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A single atom layer of gold: Researchers create goldene

Science Daily: Pharmacology News

For the first time, scientists have managed to create sheets of gold only a single atom layer thick. The material has been termed goldene. According to researchers, this has given the gold new properties that can make it suitable for use in applications such as carbon dioxide conversion, hydrogen production, and production of value-added chemicals.

Research 129
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AI-Driven Drug Discovery: Transforming the Landscape of Pharmaceutical Research

Drug Patent Watch

The pharmaceutical industry in China is undergoing a significant transformation with the adoption of artificial intelligence (AI) technology.

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Most massive stellar black hole in our galaxy found

Science Daily: Pharmacology News

Astronomers have identified the most massive stellar black hole yet discovered in the Milky Way galaxy. This black hole was spotted in data from the European Space Agency's Gaia mission because it imposes an odd 'wobbling' motion on the companion star orbiting it. Astronomers have verified the mass of the black hole, putting it at an impressive 33 times that of the Sun.

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ChEMBL 34 is out!

The ChEMBL-og

We are delighted to announce the release of ChEMBL 34, which includes a full update to drug and clinical candidate drug data. This version of the database, prepared on 28/03/2024 contains: 2,431,025 compounds (of which 2,409,270 have mol files) 3,106,257 compound records (non-unique compounds) 20,772,701 activities 1,644,390 assays 15,598 targets 89,892 documents Data can be downloaded from the ChEMBL FTP site: [link] Please see ChEMBL_34 release notes for full details of all changes in this rel

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Plastic pollution can kill variety of ocean embryos

Science Daily: Pharmacology News

High levels of plastic pollution can kill the embryos of a wide range of ocean animals, new research shows.

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Perficient Included in IDC Market Glance: Payer, 2Q24

Perficient: Drug Development

Health insurers today are facing a rapidly evolving landscape of complex expectations and requirements. Whether it’s responding to government mandates regarding interoperability and data privacy or customer demand for a seamless digital experience, constant evolution is key to staying at the forefront of industry standards. Your future success will be determined by the investments you make now in your capabilities and technology.

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More Trending

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Characterization of hOAT4 and mOat5 as functional orthologs for renal anion uptake and efflux transport [Metabolism, Transport, and Pharmacogenetics]

ASPET

Organic anions (OA) are compounds including drugs or toxicants that are negatively charged at physiological pH and are typically transported by Organic Anion Transporters (OATs). Human OAT4 (SLC22A11) is expressed in the apical membrane of renal proximal tubules. Although there is no rodent ortholog of hOAT4, rodents express Oat5 (Slc22a19), an anion exchanger that is also localized to the apical membrane of renal proximal tubule cells.

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'One and Done': Scientists Develop Vaccine That May Fight Any Viral Strain

Drugs.com

TUESDAY, April 16, 2024 -- Genetics-based “one-and-done” vaccines for the flu and COVID could prove more effective and easier to craft than current jabs, researchers report.These new vaccines would target viruses using a different response to.

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Biotech landlord Alexandria on research clusters and the sector’s recovery

BioPharma Drive: Drug Pricing

Joel Marcus, the longtime head of Alexandria Real Estate Equities, sees few near-term challengers to the established biotech hubs of Boston, San Diego and San Francisco.

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A More Diverse Nature Brings Better Mental Health

Drugs.com

TUESDAY, April 16, 2024 -- Want to feel happier?Live in or near a place with a rich diversity of nature, a new study says.Environments with plentiful natural features -- trees, birds, plants and rivers -- are associated with better mental.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Michelson Prizes, Next-Generation Grants ePanel Features Rising Stars in Immunology & Vaccine Innovation

keypoint

On May 14, 2024, Keystone Symposia will host a live ePanel event featuring the recipients of the Michelson Prizes: Next-Generation Grants , an international prize that provides $150,000 in funding to young investigators at a time in their careers when it is most difficult to secure funding for innovative work. These Next-Generation Grants aim to encourage and support early-career researchers who are applying disruptive concepts and inventive processes to advance human immunology, vaccine discove

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Nosing Out Why Kids Are Less Harmed by COVID

Drugs.com

TUESDAY, April 16, 2024 -- The nose appears to know when it comes to why children typically have milder cases of COVID-19 than seniors, a new study finds.Cells lining the inside of the nose are more likely to have a prompt immune response to COVID.

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Intra-Cellular builds case for depression drug with late-stage trial win

BioPharma Drive: Drug Pricing

Shares of the biotech rose 25% after a large trial found adding its drug Caplyta onto antidepressant therapy significantly helped people with major depression.

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Walking Your Way to Better Health

Drugs.com

TUESDAY, April 16, 2024 -- Walking is one of the best exercises available to average folks, and it can be as easy as stepping out your front door, experts say.“It is something you can easily fit into your lifestyle,” said Dr.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Cullinan changes name, pivots to autoimmune disease

BioPharma Drive: Drug Pricing

The biotech says a dual-pronged antibody it’s developing could become an “off-the-shelf” alternative to cell therapies in development for lupus and other inflammatory conditions.

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AI Matches Experts in Spotting Radiology Errors

Drugs.com

TUESDAY, April 16, 2024 -- Artificial intelligence can serve as a helpful backup editor to radiologists, making sure their reports are accurate and reliable, a new study says.The OpenAI program GPT-4 performed about as well as a group of.

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The Top 15 Specialty Pharmacies of 2023: Market Shares and Revenues at the Biggest PBMs, Health Plans, and Independents

Drug Channels

Drug Channels Institute’s (DCI’s) latest analysis finds that participants in the specialty pharmacy market continue to get more diverse—although revenues remain highly concentrated. We have identified nearly 1,800 dispensing sites with specialty pharmacy accreditation—about 40% of which are owned by hospitals, physician practices, and other healthcare providers.

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Complications in Pregnancy Linked to Long-Term Health Risks for Women

Drugs.com

TUESDAY, April 16, 2024 -- Women who experience common complications during a pregnancy could face heightened odds for early death for decades to come, new research shows.In the largest such study to date, "women who experienced any of five major.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Live and Let Dye: Self-Labeling Protein Tags

addgene Blog

If you take a look in a typical lab freezer, you’ll probably find lots of different plasmids containing the same protein of interest tagged with different fusion proteins for different experiments over the years — a green fluorescent protein, a red fluorescent protein, a fancy new green fluorescent protein, some affinity purification tags, another version with that same red fluorescent protein somebody made because they forgot it was already in the freezer… you get the idea.

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Brain's Cerebellum Could Help Direct Prosthetic Limbs

Drugs.com

TUESDAY, April 16, 2024 -- Tapping the power of the small brain region called the cerebellum could improve patients’ ability to move cutting-edge robotic limbs, a new study suggests.

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Tinker

Codon

Stage 1: Planning As soon as I’m spun up, a face fills my vision, and I realize that something’s changed. The humans evaluating my performance over the last few weeks had all been young unknowns, mostly Ph.D. students eager for extra cash. This guy is older, and I recognize him from my early training data: he’s a team lead at Magma, the company developing me.

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CDC Warns of 19 Cases of Botched Botox Shots in 9 States

Drugs.com

TUESDAY, April 16, 2024 -- Counterfeit or mishandled Botox shots have triggered harmful reactions in 19 people in nine states, U.S. health officials warned Monday.In its alert, the U.S. Centers for Disease Control and Prevention said nine people.

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Which pharmaceutical companies have the most pellets dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most pellets dosed drugs. For a different perspective, see the most popular dosage types.

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The Fourth Circuit Upholds CMS’ Definition of “Line-Extension Drug” and “New Formulation”

FDA Law Blog: Biosimilars

By Sophia R. Gaulkin — On April 10, the Fourth Circuit unanimously affirmed a summary judgment ruling for the Centers for Medicare & Medicaid Services (CMS) regarding the agency’s definitions of “line-extension drug” and “new formulation” for purposes of determining rebates that drug manufacturers may owe the Medicaid Drug Rebate Program (MDRP).

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New patent for Tolmar drug ELIGARD KIT

Drug Patent Watch

Annual Drug Patent Expirations for ELIGARD+KIT Eligard Kit is a drug marketed by Tolmar and is included in four NDAs. It is available from one supplier.

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J&J sees mixed performance from new multiple myeloma drugs

BioPharma Drive: Drug Pricing

Tecvayli sales, which J&J broke out for the first time, surpassed Wall Street forecasts and offset underperformance from Carvykti, which J&J attributed to the "phasing and timing of orders.

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New patent for Horizon Therap drug RAVICTI

Drug Patent Watch

Annual Drug Patent Expirations for RAVICTI Ravicti is a drug marketed by Horizon Therap Us and is included in one NDA. It is available from one supplier.

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Patient-Centered or Patient-Driven? Exploring New Ways of Patient Collaboration in Modern Healthcare Publishing

Fierce BioTech

Patient-Centered or Patient-Driven? Exploring New Ways of Patient Collaboration in Modern Healthcare Publishing swheeler Tue, 04/16/2024 - 13:20 Thu, 05/23/2024 - 11:00 Resource Type Webinar Bob Perry Heather Gorse Catherine Richards Golini Paul Lavender Duration 60 minutes This webinar focuses on the growing significance and value of co-creation in healthcare education, particularly in the creation of patient information resources.

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New patent for Agepha Pharma drug LODOCO

Drug Patent Watch

Annual Drug Patent Expirations for LODOCO Lodoco is a drug marketed by Agepha Pharma Fz and is included in one NDA. It is available from one supplier.

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Guide to TestCloud Tunnels Configuration for Test Execution in Private Domain

Perficient: Drug Development

Testing applications hosted locally or in private environments presents a unique challenge for testers. Accessing these applications for testing purposes requires setting up a secure connection, commonly known as a tunnel. This detailed guide will explore the concept of test cloud tunnels and provide a step-by-step configuration process to enable test execution in a private domain.

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Inside The Altascientist: The Benefits of PCR for Your Gene Therapy Programs

Alta Sciences

Inside The Altascientist: The Benefits of PCR for Your Gene Therapy Programs pmjackson Tue, 04/16/2024 - 19:04 The gene therapy landscape continues to accelerate in preclinical and clinical research, with programs constantly in development for targeted, personalized medicines. The goal is to safely incorporate genetic alterations to restore and repair the proteins of missing and/or faulty genes.

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Perficient LDC Colleagues “Take Over” St. Joseph’s Diner

Perficient: Drug Development

Take Over Begins On April 7th, the Perficient LDC Colleagues embarked on a heartfelt mission at St. Joseph’s Diner in Lafayette, Louisiana. With six eager hearts, we took over the kitchen at 613 W. Simcoe St., ready to serve those in need. St. Joseph’s Diner, a beacon of hope in the community, opens its doors daily from 11 am to 1 pm, providing free, freshly prepared, nutritious meals to individuals experiencing homelessness and hunger.

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Good Blood Pressure Control Could Prevent Fibroids

Drugs.com

TUESDAY, April 16, 2024 -- Keeping blood pressure under control could be crucial for women in preventing uterine fibroids, new research shows.Middle-aged women tracked for up to 17 years in a new study were 37% less likely to develop these painful.