rAAV Genome sequencing uncovers transgene integrity and packaging impurities
Drug Discovery World
APRIL 16, 2024
Recombinant adeno-associated viruses (rAAVs) are considered a promising delivery system for gene therapy medicines. This webinar will highlight how long-read nanopore sequencing as a comprehensive and sensitive QC method for rAAVs were evaluated — which is supporting internal research activities at AstraZeneca. Attendees will hear how library preparation, assessed data quality, and generated important rAAV metrics such as integrity of DNA cargo, truncation events, chimeric transgenes, and levels
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