Tue.Apr 16, 2024

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A single atom layer of gold: Researchers create goldene

Science Daily: Pharmacology News

For the first time, scientists have managed to create sheets of gold only a single atom layer thick. The material has been termed goldene. According to researchers, this has given the gold new properties that can make it suitable for use in applications such as carbon dioxide conversion, hydrogen production, and production of value-added chemicals.

Research 315
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Melatonin Gummies to Get Safety Labeling, Child-Safe Bottles After Poisonings

Drugs.com

TUESDAY, April 16, 2024 -- In the wake of a sharp rise in the number of young children accidentally eating melatonin supplements, an industry group has called for tougher safety guidelines for packaging and labeling the sleep-aid.

Packaging 264
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Most massive stellar black hole in our galaxy found

Science Daily: Pharmacology News

Astronomers have identified the most massive stellar black hole yet discovered in the Milky Way galaxy. This black hole was spotted in data from the European Space Agency's Gaia mission because it imposes an odd 'wobbling' motion on the companion star orbiting it. Astronomers have verified the mass of the black hole, putting it at an impressive 33 times that of the Sun.

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'One and Done': Scientists Develop Vaccine That May Fight Any Viral Strain

Drugs.com

TUESDAY, April 16, 2024 -- Genetics-based “one-and-done” vaccines for the flu and COVID could prove more effective and easier to craft than current jabs, researchers report.These new vaccines would target viruses using a different response to.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Plastic pollution can kill variety of ocean embryos

Science Daily: Pharmacology News

High levels of plastic pollution can kill the embryos of a wide range of ocean animals, new research shows.

Research 291

More Trending

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Biotech landlord Alexandria on research clusters and the sector’s recovery

BioPharma Drive: Drug Pricing

Joel Marcus, the longtime head of Alexandria Real Estate Equities, sees few near-term challengers to the established biotech hubs of Boston, San Diego and San Francisco.

Research 206
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Nosing Out Why Kids Are Less Harmed by COVID

Drugs.com

TUESDAY, April 16, 2024 -- The nose appears to know when it comes to why children typically have milder cases of COVID-19 than seniors, a new study finds.Cells lining the inside of the nose are more likely to have a prompt immune response to COVID.

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Intra-Cellular builds case for depression drug with late-stage trial win

BioPharma Drive: Drug Pricing

Shares of the biotech rose 25% after a large trial found adding its drug Caplyta onto antidepressant therapy significantly helped people with major depression.

Trials 183
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Walking Your Way to Better Health

Drugs.com

TUESDAY, April 16, 2024 -- Walking is one of the best exercises available to average folks, and it can be as easy as stepping out your front door, experts say.“It is something you can easily fit into your lifestyle,” said Dr.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Cullinan changes name, pivots to autoimmune disease

BioPharma Drive: Drug Pricing

The biotech says a dual-pronged antibody it’s developing could become an “off-the-shelf” alternative to cell therapies in development for lupus and other inflammatory conditions.

Disease 164
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AI Matches Experts in Spotting Radiology Errors

Drugs.com

TUESDAY, April 16, 2024 -- Artificial intelligence can serve as a helpful backup editor to radiologists, making sure their reports are accurate and reliable, a new study says.The OpenAI program GPT-4 performed about as well as a group of.

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J&J sees mixed performance from new multiple myeloma drugs

BioPharma Drive: Drug Pricing

Tecvayli sales, which J&J broke out for the first time, surpassed Wall Street forecasts and offset underperformance from Carvykti, which J&J attributed to the "phasing and timing of orders.

Drugs 131
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Complications in Pregnancy Linked to Long-Term Health Risks for Women

Drugs.com

TUESDAY, April 16, 2024 -- Women who experience common complications during a pregnancy could face heightened odds for early death for decades to come, new research shows.In the largest such study to date, "women who experienced any of five major.

Research 243
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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AI-Driven Drug Discovery: Transforming the Landscape of Pharmaceutical Research

Drug Patent Watch

The pharmaceutical industry in China is undergoing a significant transformation with the adoption of artificial intelligence (AI) technology.

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Brain's Cerebellum Could Help Direct Prosthetic Limbs

Drugs.com

TUESDAY, April 16, 2024 -- Tapping the power of the small brain region called the cerebellum could improve patients’ ability to move cutting-edge robotic limbs, a new study suggests.

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ChEMBL 34 is out!

The ChEMBL-og

We are delighted to announce the release of ChEMBL 34, which includes a full update to drug and clinical candidate drug data. This version of the database, prepared on 28/03/2024 contains: 2,431,025 compounds (of which 2,409,270 have mol files) 3,106,257 compound records (non-unique compounds) 20,772,701 activities 1,644,390 assays 15,598 targets 89,892 documents Data can be downloaded from the ChEMBL FTP site: [link] Please see ChEMBL_34 release notes for full details of all changes in this rel

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CDC Warns of 19 Cases of Botched Botox Shots in 9 States

Drugs.com

TUESDAY, April 16, 2024 -- Counterfeit or mishandled Botox shots have triggered harmful reactions in 19 people in nine states, U.S. health officials warned Monday.In its alert, the U.S. Centers for Disease Control and Prevention said nine people.

Disease 214
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Perficient Included in IDC Market Glance: Payer, 2Q24

Perficient: Drug Development

Health insurers today are facing a rapidly evolving landscape of complex expectations and requirements. Whether it’s responding to government mandates regarding interoperability and data privacy or customer demand for a seamless digital experience, constant evolution is key to staying at the forefront of industry standards. Your future success will be determined by the investments you make now in your capabilities and technology.

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Good Blood Pressure Control Could Prevent Fibroids

Drugs.com

TUESDAY, April 16, 2024 -- Keeping blood pressure under control could be crucial for women in preventing uterine fibroids, new research shows.Middle-aged women tracked for up to 17 years in a new study were 37% less likely to develop these painful.

Research 130
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Characterization of hOAT4 and mOat5 as functional orthologs for renal anion uptake and efflux transport [Metabolism, Transport, and Pharmacogenetics]

ASPET

Organic anions (OA) are compounds including drugs or toxicants that are negatively charged at physiological pH and are typically transported by Organic Anion Transporters (OATs). Human OAT4 (SLC22A11) is expressed in the apical membrane of renal proximal tubules. Although there is no rodent ortholog of hOAT4, rodents express Oat5 (Slc22a19), an anion exchanger that is also localized to the apical membrane of renal proximal tubule cells.

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Blinking: It's About More Than Moistening the Eye

Drugs.com

TUESDAY, April 16, 2024 -- Most folks think of blinking as the eyes' version of windshield wipers, clearing the eye of debris and maybe lubricating it, too.But blinking is much more than that, researchers report: It also helps the brain process.

Research 130
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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The Top 15 Specialty Pharmacies of 2023: Market Shares and Revenues at the Biggest PBMs, Health Plans, and Independents

Drug Channels

Drug Channels Institute’s (DCI’s) latest analysis finds that participants in the specialty pharmacy market continue to get more diverse—although revenues remain highly concentrated. We have identified nearly 1,800 dispensing sites with specialty pharmacy accreditation—about 40% of which are owned by hospitals, physician practices, and other healthcare providers.

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Live and Let Dye: Self-Labeling Protein Tags

addgene Blog

If you take a look in a typical lab freezer, you’ll probably find lots of different plasmids containing the same protein of interest tagged with different fusion proteins for different experiments over the years — a green fluorescent protein, a red fluorescent protein, a fancy new green fluorescent protein, some affinity purification tags, another version with that same red fluorescent protein somebody made because they forgot it was already in the freezer… you get the idea.

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Michelson Prizes, Next-Generation Grants ePanel Features Rising Stars in Immunology & Vaccine Innovation

keypoint

On May 14, 2024, Keystone Symposia will host a live ePanel event featuring the recipients of the Michelson Prizes: Next-Generation Grants , an international prize that provides $150,000 in funding to young investigators at a time in their careers when it is most difficult to secure funding for innovative work. These Next-Generation Grants aim to encourage and support early-career researchers who are applying disruptive concepts and inventive processes to advance human immunology, vaccine discove

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Tinker

Codon

Stage 1: Planning As soon as I’m spun up, a face fills my vision, and I realize that something’s changed. The humans evaluating my performance over the last few weeks had all been young unknowns, mostly Ph.D. students eager for extra cash. This guy is older, and I recognize him from my early training data: he’s a team lead at Magma, the company developing me.

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Which pharmaceutical companies have the most pellets dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most pellets dosed drugs. For a different perspective, see the most popular dosage types.