Thu.Sep 05, 2024

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Orphan drug prevents cell death in acute liver failure

Drug Discovery World

Biotechnology company SeaBeLife has secured orphan drug designation (ODD) from the European Medicines Agency (EMA) for its drug candidate SBL01 in the treatment of acute liver failure (ALF). ALF occurs when the liver suddenly loses its ability to function in a person without a pre-existing liver disorder, and carries a high morbidity and mortality rate (85% when transplantation is not feasible).

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Travel could be the best defense against aging

Science Daily: Pharmacology News

Forget about retinol night creams, researchers believe travel could be the best way to defy premature aging. An interdisciplinary study has applied the theory of entropy to tourism, finding that travel could have positive health benefits, including slowing down the signs of aging.

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Discover the benefits of a bespoke biosafety cabinet

Drug Discovery World

A new on-demand webinar is now available to watch for free, entitled ‘ Customising biosafety cabinets: A holistic approach ‘ Watch this on-demand webinar from Nuaire to learn more about: Situations that may require a bespoke biosafety cabinet (BSC) instead of a standard one The process to collaborate with a manufacturer to build a BSC around your needs Planning for the unique certification and service requirements of a bespoke design Watch now.

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The collapse of bat populations led to more than a thousand infant deaths

Science Daily: Pharmacology News

A new study shows that when communities experienced the near death of entire insect-eating bat populations, farmers increased their use of pesticides. This in turn increased the infant mortality rate.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Customizing Biosafety Cabinets: A Holistic Approach

Drug Discovery World

Watch this on-demand webinar to learn more about: Situations that may require a bespoke biosafety cabinet (BSC) instead of a standard one The process to collaborate with a manufacturer to build a BSC around your needs Planning for the unique certification and service requirements of a bespoke design The post Customizing Biosafety Cabinets: A Holistic Approach appeared first on Drug Discovery World (DDW).

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Scientists make tissue of living animals see-through

Science Daily: Pharmacology News

In a pioneering new study, researchers made the skin on the skulls and abdomens of live mice transparent by applying to the areas a mixture of water and a common yellow food coloring called tartrazine.

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More Trending

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Ketamine Can Fight Depression, But Pregnant Women Face Risks

Drugs.com

THURSDAY, Sept. 5, 2024 -- Ketamine is becoming a popular depression drug, but doctors aren’t keeping in mind the danger it can pose to a pregnancy, a new study warns.Ketamine can be very harmful to a developing fetus and should not be used during p.

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Women in STEM with Kristina Torfgard

Drug Target Review

Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? I am a pharmacist by training and continued with a PhD in Clinical Pharmacology. However, my goal was all the time to work with drug development in the pharma industry, so I moved on and started that journey in 1992 when I took on a role as Clinical Research Manager at AstraHässle, a mid-size Swedish pharma company.

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The 3 Best Ways to Stop Smoking, Rated by Science

Drugs.com

THURSDAY, Sept. 5, 2024 -- Thinking about quitting smoking?There are three top ways to help you stop, a new review finds.According to the study, folks wanting to quit should turn to:Varenicline, a prescription nicotine-blocking drug sold under the.

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The Role of Green Chemistry in Generic Drug Development: A Sustainable Approach to Medicine

Drug Patent Watch

The pharmaceutical industry is a significant contributor to global carbon emissions, with a projected increase of over 300% by 2050 if left unchecked. This alarming trend has led to a growing need for sustainable practices in the industry, particularly in the development of generic drugs.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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States With Strictest Abortion Laws Offer Least Family Support: Study

Drugs.com

THURSDAY, Sept. 4, 2024 -- States with the most severe abortion restrictions are the least likely to offer support to struggling families, a new study has found.Anti-abortion states tend to have assistance programs that exclude many families on the.

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Gravitational waves unveil previously unseen properties of neutron stars

Science Daily: Pharmacology News

A better understanding of the inner workings of neutron stars will lead to a greater knowledge of the dynamics that underpin the workings of the universe and also could help drive future technology. A new study details how new insights into how dissipative tidal forces within double -- or binary -- neutron star systems will inform our understanding of the universe.

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Marijuana Use Raises Workers' Absenteeism Rate: Study

Drugs.com

THURSDAY, Sept. 5, 2024 -- The stereotype of the slacker stoner might not be too far off the mark, a new study shows.People who use weed are prone to workplace absenteeism -- and the more problematic the cannabis use, the more likely they are to.

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Lilly builds case for weekly insulin shot

BioPharma Drive: Drug Pricing

New data show Lilly’s longer-lasting insulin matched daily shots in controlling blood sugar, adding to positive findings the company disclosed in May.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Most U.S. Seniors Prescribed at Least 1 Drug, But Many Skip Meds Due to Cost

Drugs.com

THURSDAY, Sept. 5, 2024 -- Too many U.S. seniors are skipping their prescription meds due to cost, and the problem is most acute among the poor and chronically ill, new data shows.Almost all (88.6%) Americans age 65 or older have been prescribed at.

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Novel study reveals how aging immune system fuels cancer growth, potentially opening new avenues for prevention

Science Daily: Pharmacology News

A novel study addresses a critical yet under-explored question in cancer research: Why is aging the biggest risk factor for cancer? The study reveals how an aging immune system spurs tumor growth, offering new insights into cancer prevention and treatment, especially for older adults. In preclinical models, the research team found that anakinra, a drug typically used for inflammatory conditions such as rheumatoid arthritis, can be repurposed to block harmful signals between early lung cancer les

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U.S. Youth Vaping Drops to Lowest Level in a Decade

Drugs.com

THURSDAY, Sept. 5, 2024 -- Just 5.9% of American middle and high school students now vape, a big drop from the 7.7% who did so a year ago, new government data shows.Put another way, about 1.6 million youth now say they used e-cigarettes at least.

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Researchers discover a space oddity -- an exoplanet moving in mysterious ways

Science Daily: Pharmacology News

A research team has discovered a small planet that displays peculiar orbital motion. The shimmying planet, located 455 light-years from Earth, shows that planetary systems can be considerably more complex than researchers have previously thought.

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Map Shows U.S. Areas Where Amputation for Poor Leg Circulation Is High

Drugs.com

THURSDAY, Sept. 5, 2024 -- A new interactive map of the United States can show people the risk of leg, foot or toe amputations due to peripheral artery disease (PAD) in their locale.Mississippi has the highest risk of lower limb amputation.

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Antibodies 101: Fab Fragments

addgene Blog

Imagine an antibody. Do you immediately visualize a Y-shaped protein reminiscent of the Addgene mascot Abi? If so, you are not alone. Full-sized antibodies dominate the world of research affinity reagents, and for good reason. However, sometimes you want a tool that is a little more compact — more of an antibody fragment rather than the whole thing.

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Is this drug the answer to cannabis addiction?  

Drug Discovery World

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Amid Shortages, U.S. Allows Expanded Production of ADHD Drug Vyvanse

Drugs.com

THURSDAY, Sept. 5, 2024 -- The maker of the ADHD drug Vyvanse has been given approval by the U.S. Drug Enforcement Administration to make more of the medication as a shortage of the critical drugs continues.Following a request from the U.S. Food.

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Genetic Matchmaker: Finding Patients for Rare Disease Trials

Fierce BioTech

Genetic Matchmaker: Finding Patients for Rare Disease Trials pesurya Thu, 09/05/2024 - 11:34 Thu, 10/24/2024 - 13:00 Resource Type Webinar Sara Riordan, MS, CGC Duration 60 Minutes With 80% of rare diseases having a genetic basis, the role of genetic counselors is critical to finding patients whose molecular diagnoses match study criteria for new targeted gene therapies.

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Both Dogs and Cats Can Love a Game of 'Fetch,' Study Finds

Drugs.com

THURSDAY, Sept. 5, 2024 -- 'Fetch': It's not just for dogs.New research finds that lots of cats -- 41% -- love retrieving toys tossed by their human. “Although cats and dogs are very different in many aspects of their behavior and in how they ended.

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Why Managing Product Data In Your ERP Is Not A Good Idea

Perficient: Drug Development

If you are part of an organization that utilizes an Enterprise Resourcing Planning (ERP) system, then you probably already know the many reasons why it serves as such an essential component for your business. There are more ERP platform options today than ever before, and each system has its own collection of features and capabilities. Generally speaking, they are the work horses for managing and streamlining day-to-day business operations.

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New 'AI Stethoscope' Can Spot Pregnancy-Linked Heart Failure

Drugs.com

THURSDAY, Sept. 5, 2024 -- An AI-enhanced digital stethoscope can help doctors detect a potentially deadly form of heart failure that can occur late in pregnancy, a new clinical trial reports.The AI-driven stethoscope was 12 times more likely than.

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Overcoming drug development hurdles with phase-appropriate technology transfers

Fierce BioTech

Overcoming drug development hurdles with phase-appropriate technology transfers Discover how phase-appropriate technology transfers can help you overcome regulatory challenges, reduce costs, and accelerate your path to commercialization. Learn strategies to maximize efficiency and focus on what you do best—innovating new therapies. jpiatt Thu, 09/05/2024 - 14:54 Facing roadblocks in drug development?

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Dirty Air Could Harm Men's Fertility, Noise Could Harm Women's

Drugs.com

THURSDAY, Sept. 5, 2024 -- City living may be tough on couples wanting to conceive: New data shows that air pollution appears to be linked to lower fertility in men, while noisy traffic could harm the fertility of women.“If our results are c.

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The Care and Feeding of FDA PMAs: Mastering Premarket Approval

thought leadership

Congratulations, FDA has approved your PMA! Now what? Securing a Premarket Approval (PMA) from the FDA is a significant achievement for any medical device manufacturer—a validation of your product's safety and effectiveness. But the journey doesn't end there. The real challenge begins post-approval, where careful management of your PMA is crucial to ensure ongoing compliance, maintain market access, and safeguard your product's reputation.

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We Are ZoBio

Zobio

Step into the world of ZoBio and discover what makes us unique. Featuring our incredible team, this video captures the heart of our company - our values, our innovation, and the people who bring it all to life. From everyday interactions to groundbreaking projects, we showcase why ZoBio is a place where passion meets purpose. Het bericht We Are ZoBio verscheen eerst op ZoBio - Drug Discovery Technology.

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Compound Management

Sygnature Discovery

Accelerate the entire drug discovery process with increased accuracy and tracking with our state-of-the-art compound management facility. Compound management is central to the drug discovery workflow, encompassing the logistics, storage, tracking, dispensing, and preparation of compounds for testing and analysis. Our facility ensures this process is executed flawlessly to prevent any disruptions that could delay the release of effective and viable therapeutics.

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Lykos CEO to depart after FDA rejection, layoffs

BioPharma Drive: Drug Pricing

The departure of Amy Emerson as CEO comes three weeks after the MDMA developer revealed plans to cut 75% of its staff.

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New Findings on the Sinclair Nanopig™ in Safety Studies

Alta Sciences

New Findings on the Sinclair Nanopig™ in Safety Studies blussier Thu, 09/05/2024 - 18:00 HTML Recent Scientific Data Challenges the Status Quo Our most recent white paper presents detailed genomic, proteomic, and functional data on the Sinclair Nanopig™’s metabolism and immune systems. These findings validate this animal model as a valuable tool for regulatory pharmacology and drug safety, enhancing cross-species assessments and improving understanding of drug metabolism and potential toxicities

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NMR: an indispensable ADME tool

Metabolite Tales Blog

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