Fri.Nov 22, 2024

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Woman Receives World's First Robotic Double-Lung Transplant

Drugs.com

FRIDAY, Nov. 22, 2024 -- A 57-year-old woman with COPD has received the world's first fully robotic double lung transplant.The breakthrough surgery was performed in October at NYU Langone Health in New York City by Dr. Stephanie Chang. Just a month.

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BridgeBio heart drug approved by FDA, setting up battle with Pfizer

BioPharma Drive: Drug Pricing

The approval of Attruby for transthyretin amyloidosis with cardiomyopathy begins a battle for control of a lucrative market that investors have been skeptical BridgeBio can win.

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Bird Flu Virus in Canadian Teen Shows Mutations That Could Help It Spread Among Humans

Drugs.com

FRIDAY, Nov. 22, 2024 -- In a development that health experts have warned might come, Canadian officials report that the bird flu virus isolated from a sick teen in Vancouver shows mutations that could help it spread more easily among humans.At.

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Early Mesoamericans trapped fish far earlier than previously thought

Science Daily: Pharmacology News

Archaeologists have collected data which indicates the presence of a large-scale pre-Columbian fish-trapping facility. Discovered in the Crooked Tree Wildlife Sanctuary (CTWS), the largest inland wetland in Belize, the team dated the construction of these fisheries to the Late Archaic period (cal. 2000-1900 BCE), pre-dating Amazonian examples by a thousand years or more.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Short-Term Hormone Therapy for Menopause Won't Harm Women's Brains

Drugs.com

FRIDAY, Nov. 22, 2024 -- Four years of hormone replacement therapy to help women deal with menopausal symptoms causes no harm to the brain, even over the long term, new research shows."In the present study, approximately 10 years after 48 months of.

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New gene drive reverses insecticide resistance in pests. then disappears

Science Daily: Pharmacology News

Geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an 'e-Drive' that reverses insecticide resistance and then disappears from the insect population.

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Covalent Targeting of Histidine Residues with Aryl Fluorosulfates: Application to Mcl-1 BH3 Mimetics

Covalent Modifiers

Giulia Alboreggia, Parima Udompholkul, Emma L. Atienza, Kendall Muzzarelli, Zahra Assar, and Maurizio Pellecchia Journal of Medicinal Chemistry 2024 DOI: 10.1021/acs.jmedchem.4c01541 Covalent drugs provide pharmacodynamic and pharmacokinetic advantages over reversible agents. However, covalent strategies have been developed mostly to target cysteine (Cys) residues, which are rarely found in binding sites.

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Reading Beyond Headline Rare For Most on Social Media, Study Finds

Drugs.com

FRIDAY, Nov. 22, 2024 -- Three out of four times, your Facebook friends don't read past the headline when they share a link to political content. Experts say that's somewhat surprising -- and downright scary. People who share without clicking may.

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Halozyme drops Evotec buyout bid; Patient dies in Neurogene trial

BioPharma Drive: Drug Pricing

Evotec appears to have rebuffed Halozyme’s $2.1 billion acquisition attempt. Elsewhere, Argenx has another blockbuster target in sight and an FDA veteran plans retirement.

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Flu, COVID Vaccination Rates Remain Low as Winter Nears

Drugs.com

FRIDAY, Nov. 22, 2024 -- Worn down by pandemic-era vaccine overload, many Americans are ignoring pleas by health officials to get immunized against the flu and COVID-19, new data shows.According to U.S. Centers for Disease Control and Prevention.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Johns Hopkins surgeon Makary is Trump’s pick to lead FDA

BioPharma Drive: Drug Pricing

A prolific medical research and author, Martin Makary criticized the FDA and CDC for their decision-making during the pandemic, although he describes himself as pro-vaccine.

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Could a Vitamin Be Effective Treatment for COPD?

Drugs.com

FRIDAY, Nov. 22, 2024 -- A daily dose of vitamin B3 reduced inflammation in the lungs of patients with COPD, Danish researchers report. "This is significant, because inflammation can lead to reduced lung function in these patients," said researcher.

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Lexicon to disband sales team, lay off 60% of staff

BioPharma Drive: Drug Pricing

The restructuring follows the company's receipt of a letter from the FDA citing "deficiencies" in its approval application for diabetes drug Zynquista.

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AI in Pharma: Benefits, Risks and the Road Ahead

Fierce BioTech

AI in Pharma: Benefits, Risks and the Road Ahead AI is revolutionizing the drug development process, streamlining and accelerating every stage, from research to approval and marketing. This whitepaper explores the benefits and risks of AI in the pharmaceutical industry and examines its future. jkarimi Fri, 11/22/2024 - 15:01 AI is revolutionizing the drug development process, streamlining and accelerating every stage, from research to approval and marketing.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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CDMO Vendor Management: Best Practices

Drug Patent Watch

The pharmaceutical industry has increasingly turned to contract development and manufacturing organizations (CDMOs) to optimize their facilities and outsource non-core production. Effective CDMO vendor management is crucial for the success of these partnerships. Here, we outline best practices for selecting, qualifying, and managing CDMOs.

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5 Ways Drupal Starshot Will Supercharge Your Website in 2025

Perficient: Drug Development

In today’s fast-paced digital landscape, enterprise organizations face a constant challenge: delivering exceptional digital experiences at scale while maintaining efficiency, consistency, and adaptability. The need for robust, user-friendly solutions has never been more critical, and Drupal’s latest innovation, Starshot, promises to redefine how enterprises build and manage their digital ecosystems.

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Fibroids, Endometriosis Linked to Shorter Life Spans

Drugs.com

FRIDAY, Nov. 22, 2024 — Two conditions common during women's childbearing years may increase their odds for serious illness and premature death, a large study shows.Drawing on data from close to 111,000 women and three decades of monitoring, r.

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How Can High Content Imaging Transform Your Cancer Research?

Crown Bioscience

The field of oncology research demands innovative, multi-dimensional approaches to tackle the complexities of cancer biology, therapeutic responses, and immune interactions. High Content Imaging (HCI) is revolutionizing this space, combining automated microscopy, advanced imaging, and data analytics to provide unparalleled insights into cellular behaviors.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Flavored Vapes Behind Big Surge in U.S. E-Cigarette Sales

Drugs.com

FRIDAY, Nov. 22, 2024 — E-cigarettes flew off store shelves between 2019 and 2023, and 80% were in youth-friendly flavors like fruit, candy, mint and menthol.In all, e-cigarette sales rose 47% over the period, according to a new report from the CDC.

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Addressing Gaps in Access: Strategies to Optimize Your Prescription Journey

Drug Channels

Today’s guest post comes from Catherine Wood Hill, SVP of Marketing at PHIL. Catherine reviews the prescription lifecycle from the perspectives of patients, providers, and manufacturers. She explains how manufacturers can support patients with clear comunication about their prescriptions. Catherine then outlines five strategies to help providers have more informed conversations with patients.

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'10 Americas:' Health Disparities Mean Life Expectancy Varies Across U.S.

Drugs.com

FRIDAY, Nov. 22, 2024 -- How long Americans can expect to live varies dramatically -- and the gap continues to widen.A new report says health inequalities have, in essence, created 10 Americas.These mutually exclusive populations are divided along.

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Will Walgreens’ store closures disrupt its clinical trial aims?

BioPharma Drive: Drug Pricing

Despite plans to shutter 1,200 stores, the company’s chief clinical trials officer said the pharmacy giant remains committed to aiding drug research.