Tue.Dec 03, 2024

article thumbnail

Tiny, daily bursts of vigorous incidental physical activity could almost halve cardiovascular risk in middle-aged women

Science Daily: Pharmacology News

An average of four minutes of incidental vigorous physical activity a day could almost halve the risk of major cardiovascular events, such as heart attacks, for middle-aged women who do not engage in structured exercise, according to new research.

Research 115
article thumbnail

In-Silico Antibody Development with AlphaBind Using NVIDIA BioNeMo and AWS HealthOmics

Nvidia Developer: Drug Discovery

Antibodies have become the most prevalent class of therapeutics, primarily due to their ability to target specific antigens, enabling them to treat a wide range. Antibodies have become the most prevalent class of therapeutics, primarily due to their ability to target specific antigens, enabling them to treat a wide range of diseases, from cancer to autoimmune disorders.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Countdown to an ice-free Arctic: New research warns of accelerated timelines

Science Daily: Pharmacology News

Scientists demonstrate how a series of extreme weather events could lead to the Arctic's first ice-free day within just a few years.

Research 101
article thumbnail

Aucatzyl, a New Hope Against a Tough-to-Treat Leukemia in Adults

Drugs.com

TUESDAY, Dec. 3, 2024 -- A newly approved immunotherapy can help adults with a difficult-to-treat form of leukemia, clinical trial results show. Aucatzyl (obecabtagene autoleucel) worked on more than three-quarters (76%) of patients with B-cell.

article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Janux impresses Wall Street with new prostate cancer drug results

BioPharma Drive: Drug Pricing

While early and from a small trial, the findings suggest Janux’s method of “masking” T cell engagers could lead to differentiated results, some analysts said.

Trials 64
article thumbnail

New planet in Kepler-51 system discovered using James Webb Space Telescope

Science Daily: Pharmacology News

An unusual planetary system with three known ultra-low density 'super-puff' planets has at least one more planet, according to new observations.

73

More Trending

article thumbnail

Can plastic-eating bugs help with our microplastic problem?

Science Daily: Pharmacology News

Previous research found that insects can ingest and absorb pure, unrefined microplastics -- but only under unrealistic, food-scarce situations. Zoologists have now tested mealworms in a more realistic scenario, feeding them ground-up face masks -- a common plastic product -- mixed with bran, a tastier option. After 30 days, the research team found the mealworms ate about half the microplastics available, about 150 particles per insect, and gained weight.

article thumbnail

New Weight-Loss Advance: A Gastric Balloon You Control to Feel Full or Not

Drugs.com

TUESDAY, Dec. 3, 2024 -- GLP-1 meds are all the rage for weight loss nowadays, but not everyone can safely take the drugs to shed pounds. Invasive weight-loss surgeries can often be a tough sell, too. Now, researchers at the Massachusetts Institute.

article thumbnail

Understanding data(), Interpolation and Computed Properties in Vue.js

Perficient: Drug Development

How to Easily Manage and Display Data in Vue.js? Are you building a dynamic, interactive Vue.js app and wondering how to manage and display data efficiently? In this guide, we’ll show you how to easily store data, display it instantly on your page with Vue’s interpolation, and optimize complex calculations with computed properties. These features will help your app run faster and smoother than ever!

59
article thumbnail

Coherus, sharpening immuno-oncology focus, sells another biosimilar for over $500M

BioPharma Drive: Drug Pricing

The company reached a deal to divest its third biosimilar this year, selling a copycat version of Amgen’s Neulasta for up to $558 million.

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Logging Mechanization and Impacts on Health

NIOSH Science Blog: Drugs

While logging is still considered a high-risk industry, the mechanization of work has contributed to critical safety improvements. When at one time most loggers performed manual felling, today a logger’s workday is increasingly spent seated while operating heavy equipment. There is no doubt that mechanization has changed the industry in many ways. Researchers at the Northeast Center for Occupational Safety and Health in Agriculture, Forestry, and Fishing (Northeast Center), one of twelve funded

article thumbnail

Legacy Systems Explained: Why Upgrading Them is Crucial for Your Business

Perficient: Drug Development

What are Legacy Systems? Why is Upgrading those Systems Required? Upgrading means more than just making practical improvements to keep things running smoothly. It addresses immediate needs rather than chasing a perfect but impractical solution. The situation could spiral out of control if things don’t function properly in real-time. One such incident happened on January 4, 2024, when South Africa’s Department of Home Affairs was taken offline nationwide due to a mainframe failure.

article thumbnail

Newly Approved Aucatzyl Provides New Hope Against a Tough-to-Treat Leukemia in Adults

Drugs.com

TUESDAY, Dec. 3, 2024 -- A newly approved immunotherapy can help adults with a difficult-to-treat form of leukemia, clinical trial results show. Aucatzyl (obecabtagene autoleucel) worked on more than three-quarters (76%) of patients with B-cell.

article thumbnail

Master SFMC Content Builder: A Complete Guide

Perficient: Drug Development

Creating engaging content that resonates with your audience is the cornerstone of successful marketing. Salesforce Marketing Cloud (SFMC) Content Builder simplifies this process by offering a unified platform for designing, managing, and deploying content across multiple channels. Whether you’re a beginner or a seasoned marketer, Content Builder empowers you to craft personalized, impactful campaigns with ease.

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Deep Belly Fat May Help Spur Alzheimer's Decades Before Symptoms Begin

Drugs.com

TUESDAY, Dec. 3, 2024 -- An accumulation of fat lurking around the organs of obese people is strongly linked to a buildup of Alzheimer's-linked proteins in the brain, new research finds.Buildup of this visceral fat in middle age may boost levels of.

article thumbnail

Harnessing the Power of SFMC Contact Builder

Perficient: Drug Development

In today’s era of data-driven marketing, the ability to understand and engage customers on a personal level is more important than ever. Salesforce Marketing Cloud (SFMC) offers a robust suite of tools to help marketers achieve this, and at the center of it all is Contact Builder —a powerful feature designed to manage and unify customer data for actionable insights and precise targeting.

article thumbnail

The Future of Life Sciences is Super Bright – Learnings from the Veeva Commercial Summit in Madrid

ACTO

Now that the jet lag has faded, I’ve been reflecting on my experiences from the recent Veeva Commercial Summit in Madrid. Kidding aside, it was more than a chance to network with pharma and biotech industry leaders; it was an opportunity to reinforce ACTO’s mission and our vision for the future of Life Sciences in Europe. As we broaden our global presence, the insights and connections made at the Summit will play a pivotal role in shaping our strategy and influence in this market.

Science 52
article thumbnail

Integrating Real-World Data into Coveo Search Using the Generic REST API Source Connector

Perficient: Drug Development

This blog will guide you through indexing content from API endpoints into Coveo using the Generic REST API source. This tool allows the indexing of data from any web service exposing a REST API, such as Content Management Systems (CMS), databases, or third-party platforms. While the demo API here is for illustration, the steps can be adapted for real-world scenarios, like integrating Adobe Experience Manager (AEM) data or fetching structured content, such as user profiles or metadata, from vario

52
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

New Hope Against a Tough-to-Treat Leukemia in Adults

Drugs.com

TUESDAY, Dec. 3, 2024 -- A newly approved immunotherapy can help adults with a difficult-to-treat form of leukemia, clinical trial results show.Aucatzyl (obecabtagene autoleucel) worked on more than three-quarters (76%) of patients with B-cell.

article thumbnail

Common Injection Routes in Mice

addgene Blog

Injections in mice are a day-to-day task for many labs. Deciding which type of injection to use depends on a number of factors. You have to weigh the pros and cons of various methods and choose what is best for you — and the mice. While not an exhaustive list, these can include what’s being injected, the type of experiment, the number of mice, the potential pain or discomfort of the mice, and restraint method.

DNA 52
article thumbnail

Artery Procedure May Offer Surgery-Free Way to Ease Knee Arthritis

Drugs.com

TUESDAY, Dec. 3, 2024 -- Blocking blood flow to the site of knee arthritis can reduce pain and potentially prevent the need for knee replacement surgery, a new study says.The procedure, called genicular artery embolization (GAE), improved patients’.

52
article thumbnail

How Does Imaging Support the Development of New Therapeutics: A Focus on ADC and Radioisotope Therapy

Fierce BioTech

How Does Imaging Support the Development of New Therapeutics: A Focus on ADC and Radioisotope Therapy Discover insights from experts on advancing ADC and RIT therapies. This summary highlights how advanced imaging improves trial design, accelerates approvals, and informs decisions between ADCs and RITs. Learn how these innovations enhance patient access to cutting-edge cancer treatments. dfarris Tue, 12/03/2024 - 09:39 Discover insights from experts on advancing ADC and RIT therapies.

article thumbnail

Deep Brain Stimulation Helps Two Patients Walk After Spinal Cord Injury

Drugs.com

TUESDAY, Dec. 3, 2024 -- In 2006, Wolfgang Jäger was in his 30s when a skiing accident left the young Austrian wheelchair-bound from a spinal cord injury.Fast-forward to today, where an innovative deep-brain stimulation technique is helping the.

52
article thumbnail

The Role of Artificial Intelligence (AI) and Machine Learning (ML) in Drug Repurposing

Drug Patent Watch

In the ever-evolving landscape of pharmaceutical research and development, a revolutionary force is reshaping the way we approach drug discovery and repurposing. This force is none other than Artificial Intelligence (AI) and Machine Learning (ML).

Drugs 52
article thumbnail

Temporary Scalp Tattoo Can Track Your Brainwaves

Drugs.com

TUESDAY, Dec. 3, 2024 -- Folks soon might have their brain activity scanned using a temporary tattoo, a new study suggests.This temporary scalp tattoo allowed researchers to track electrical brain activity much more easily than with conventional.

article thumbnail

Common Reasons for Drug Patent Rejections and Solutions

Drug Patent Watch

The process of obtaining a patent for a drug invention can be complex and time-consuming. Despite the best efforts of inventors and patent attorneys, many drug patent applications are rejected by patent offices. Understanding the common reasons for these rejections is crucial for overcoming them and securing patent protection for innovative pharmaceuticals.

Drugs 52
article thumbnail

Maintain Muscle as You Age to Keep Brain Sharp

Drugs.com

TUESDAY, Dec. 3, 2024 -- Maintaining muscle might be one way to help prevent dementia, new research suggests.“We found that older adults with smaller skeletal muscles are about 60% more likely to develop dementia when adjusted for other known risk f.

article thumbnail

Understanding Custom Events in Vue.js

Perficient: Drug Development

Are You Struggling with Component Communication in Vue.js? Building dynamic, maintainable applications in Vue.js requires seamless communication between components. But how can you ensure that your child components communicate effectively with their parent components—without creating a tangled mess of props, state management, and confusing logic? Custom events in Vue.js offer a clean, simple, and powerful way to solve this problem, allowing your app to stay flexible, scalable, and easy to mainta

52
article thumbnail

Need Some 'Alone Time'? It's Vital to Mental Health for Many

Drugs.com

TUESDAY, Dec. 3, 2024 -- The hectic holidays play havoc on people’s nerves, not the least because they aren’t able to have any time to themselves.Nearly half (46%) of Americans say they don’t get the alone time they need during the holidays, accor.

52
article thumbnail

Four Revelations from Minnesota’s First 340B Transparency Report

Drug Channels

It’s time to pay attention to the money behind the 340B curtain. Minnesota just released the industry‘s first ever mandated financial report on the 340B Drug Pricing Program. Below, I do a wicked deep dive into the data and highlight crucial implications about spending, profits, pharmacies, plans, patients, program integrity, and more. There are important limitations to these data.

article thumbnail

Elton John Says He Has Lost His Sight

Drugs.com

TUESDAY, Dec. 3, 2024 -- Pop music legend Elton John says that he can no longer see following an eye infection he battled last summer.The prolific singer-songwriter made the announcement Sunday at a charity gala performance of "The Devil Wears.

52
article thumbnail

An In-Depth Look at Objects in JavaScript

Perficient: Drug Development

Basics of Objects in JavaScript JavaScript is an object-based language; its objects are made up of attributes. If an attribute contains a function, it is considered a method; otherwise, it is a property. JavaScript provides objects and arrays for gathering and referring to related sets of data under a single name. How to Create an Object in JavaScript There are several ways to create an object in JavaScript: 1.

52
article thumbnail

Note from the Editor-in-Chief

BioPharma Drive: Drug Pricing

A change in ownership and what it means for our readers.

52