Fri.Feb 14, 2025

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Does planetary evolution favor human-like life? Study ups odds we're not alone

Science Daily: Pharmacology News

Humanity may not be extraordinary but rather the natural evolutionary outcome for our planet and likely others, according to a new model for how intelligent life developed on Earth.

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Do Steroid Shots Help Ease Back Pain? Experts Weigh In

Drugs.com

FRIDAY, Feb. 14, 2025 -- There appears to be limited evidence supporting the use of epidural steroid injections for certain types of chronic lower back pain, new guidance from the American Academy of Neurology (AAN) finds. Epidural steroid.

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Climate change threatens global cocoa production: New study highlights pollination-based solutions

Science Daily: Pharmacology News

This Valentine's Day, millions of pounds worth of chocolate will be exchanged as gifts, but climate change and biodiversity loss imperil future global supplies of this treat. A new research study demonstrates that sustainable agricultural practices that both protect pollinator populations and mitigate climate risks could help secure -- and even improve -- global cocoa yields.

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American Cancer Society Calls for Restoration of Key CDC, FDA Data

Drugs.com

FRIDAY, Feb. 14, 2025 -- With certain government data currently being withheld, removed, or restored but partially redacted on the websites of the U.S. Centers for Disease Control and Prevention and Food and Drug Administration, the American Cancer.

FDA 261
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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A diabetes, heart failure, and kidney disease medication is the first of its kind to significantly reduce both heart attacks and strokes

Science Daily: Pharmacology News

New research shows sotagliflozin is the only drug in its class to demonstrate these results.

Disease 246

More Trending

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A new switch for the cell therapies of the future

Science Daily: Pharmacology News

Researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin. One day, researchers want to use switches of this kind to trigger cell therapies for various metabolic diseases.

Therapies 245
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Igloo Recalls 1M Rolling Coolers Over Risk of Fingertip Amputations

Drugs.com

FRIDAY, Feb. 14, 2025 -- Popular cooler brand Igloo has recalled more than 1 million rolling coolers due to serious fingertip injury risk.The U.S. Consumer Product Safety Commission (CPSC) said the recall affects 90-quart Flip & Tow Rolling.

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Evidence of play-like interaction with carousel in insects

Science Daily: Pharmacology News

Scientists have for the first time demonstrated play-like behavior in flies. They found that fruit flies (Drosophila melanogaster) voluntarily and repeatedly visited a carousel.

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CDD Vault Update (February 2025) - Release Notes

Collaborative Drug

We are excited to announce a new round of features associated with our Curves Add-on. If you are not yet subscribed to Curves, please contact your CDD Vault account manager or the CDD Vault Support Team to discuss enabling these features in your Vault.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Under-sea mountains are key 'hubs' for sharks

Science Daily: Pharmacology News

Under-sea mountains are key locations for predators -- with 41 times more sharks than the open ocean, new research shows.

Research 217
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‘It’s not for the faint of heart.’ How 3 CEOs took their biotechs public

BioPharma Drive: Drug Pricing

Speaking this week at BIO CEO, the heads of Septerna, Upstream Bio and Actuate Therapeutics shared lessons from going public in a challenging market for biotech stocks.

Marketing 164
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'Game changing' release of Type Ia Supernovae data may hold key to the history of the Universe

Science Daily: Pharmacology News

A unique dataset of Type Ia Supernovae being released today could change how cosmologists measure the expansion history of the Universe.

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Zoo Workers Battle Grief When Animals in Their Care Die

Drugs.com

FRIDAY, Feb. 14, 2025 -- Zoo workers and volunteers often grieve when animals die, and zoo managers can do a better job of supporting them, a new study finds.Zoo professionals and volunteers frequently face significant emotional strain due to a.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Mouse study finds impaired cell development: Intermittent fasting could be unsafe for teenagers

Science Daily: Pharmacology News

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers discovered that chronic intermittent fasting disrupted the development of insulin-producing beta cells in young mice. The findings raise concerns about potential risks for humans, especially teenagers.

Research 206
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Seniors, Could Working Later in Life Be Healthy?

Drugs.com

FRIDAY, Feb. 14, 2025 -- Most people who are working after age 50 say staying on the job boosts their health and well-being, and those over 65 report the most benefit, a new University of Michigan poll finds.The poll of 3,486 U.S. adults aged 50-94.

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Deposits found on a nearby asteroid point to salty water in the outer Solar System

Science Daily: Pharmacology News

Asteroids that orbit close to the Earth inevitably cause us some anxiety due to the even remote possibility of a collision. But their proximity also offers ample opportunities to learn more about the universe. Ryugu, a 900-meter diameter asteroid in the Apollo belt, has recently proven useful in our search for signs of life's precursors elsewhere in our Solar System.

Research 185
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Americans Who’ve Become Caregivers Rose by a Third in 10 Years

Drugs.com

FRIDAY, Feb. 14, 2025 A growing numbers of family members now provide care for older adults who live at home or in residential care settings, a new study shows.Their ranks increased 32%, from 18.2 million to 24.1 million, between 2011 and 2022, a.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Target Analysis

Sygnature Discovery

Discerning the best route to a new drug candidate can often be illuminated by building a comprehensive knowledge of a target in order to choose the best approach for a drug discovery project. Our CADD experts adopt a comprehensive target analysis approach to develop an optimal hit finding strategy and ultimately to design better, selective compounds.

Drugs 52
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STI Testing at Home? Survey Finds Many Young People Are For It

Drugs.com

FRIDAY, Feb. 14, 2025 When it comes to testing for sexually transmitted infections (STIs), many young adults prefer the privacy and convenience of at-home testing, a new survey suggests.Fully 91% of survey participants aged 14-24 said they would u.

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BIMO Listings in Clinical Trials: Ensuring Compliance & Data Integrity

Quanticate

Learn how BIMO listings help sponsors and CROs navigate FDA inspections, ensuring clinical trial compliance and data accuracy.

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Nonviral CRISPR-based knock-in of chimeric antigen receptor transgenes into T cells for cell therapy

Fierce BioTech

Nonviral CRISPR-based knock-in of chimeric antigen receptor transgenes into T cells for cell therapy dwunderlin Fri, 02/14/2025 - 14:52 Thu, 04/03/2025 - 11:00 Resource Type Webinar Krishanu Saha, PhD Max Sellman Join us for an insightful webinar on the latest advancements in cell and gene therapy, focusing on the innovative Cas9-CLIPT technology. Cas9-CLIPT (Cleaved, Linearized with Protein Template) is a groundbreaking technology designed to improve the efficiency of genome editing.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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5 Red Flags That Show Your CRO Isn’t Giving You the Attention You Deserve

Alta Sciences

5 Red Flags That Show Your CRO Isnt Giving You the Attention You Deserve blussier Fri, 02/14/2025 - 15:04 HTML Choose a CRO Who Understands Your Worth Like any good relationship, going steady with a CRO should be about mutual commitment, transparency, and shared goals. But what if your CRO isnt giving you the time and effort you deserve? Here are five red flags that show your CRO isnt making you a priorityand how Altasciences guarantees the support you deserve.

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Target Analysis

Sygnature Discovery

Discerning the best route to a new drug candidate can often be illuminated by building a comprehensive knowledge of a target in order to choose the best approach for a drug discovery project. Our CADD experts adopt a comprehensive target analysis approach to develop an optimal hit finding strategy and ultimately to design better, selective compounds.

Drugs 52
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Scientific workflow for hypothesis testing in drug discovery: Part 3 of 3

Drug Target Review

Throughout the workflow described in Figure 1, different tools can play a critical role in facilitating each stage of analysis. From hypothesis generation to data cleaning and interpretation, the appropriate use of tools can significantly improve the efficiency and accuracy of the research process. 1. Data visualisation and hypothesis generation tools Tools like Miro, that generate diagrams, are essential for mapping out hypotheses.

Drugs 52
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Virtual Screening

Sygnature Discovery

In silico -based virtual high-throughput screening (vHTS) offers an alternative, complementary and cost-effective approach to hit identification. In silico screening can involve flexible docking of millions of compounds to the biological target of interest ( structure-based virtual screening), using crystallographic data or homology models, or searching for compounds similar to known active molecules ( ligand-based virtual screening) using pharmacophores, ligand shape-electrostatic similarity or

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States With Abortion Bans See More Infant Deaths

Drugs.com

FRIDAY, Feb. 14, 2025 -- In the first 18 months after the U.S. Supreme Court overturned Roe v. Wade, most states with abortion bans saw a rise in infant deaths, new research reveals.Two studies, published Feb. 13 in JAMA, show that states that.

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