LifeSciVC

JANUARY 16, 2024

By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Just in time for new years’ reflections and resolutions, this year’s JPM felt like a refreshing burst of enthusiasm for a sector that has seen its challenges in 2022 and 2023 but also some green shoots. 2023 was a stellar year for M&A, comeback stories, burgeoning “hot” spaces, and for re-learning the basics of belt-tightening and careful capital allocation.

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Small Molecule Trials Therapies Disease 139

Practical Cheminformatics

JANUARY 16, 2024

Following up on Part I and Part II, the third post in this series is a collection of review articles published in 2023 that I found helpful.

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Targeted Protein Degradation Small Molecule Computational Chemistry Bioinformatics 141

BioPharma Drive: Drug Pricing

JANUARY 16, 2024

The agency’s decision to expand use of Casgey, which won a landmark OK for sickle cell disease in December, comes more than two months ahead of schedule.

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FDA Disease 122

Science Daily: Pharmacology News

JANUARY 16, 2024

Fossils of kelp along the Pacific Coast are rare. Until now, the oldest fossil dated from 14 million years ago, leading to the view that today's denizens of the kelp forest -- marine mammals, urchins, sea birds -- coevolved with kelp. A recent amateur discovery pushes back the origin of kelp to 32 million years ago, long before these creatures appeared.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Drugs.com

JANUARY 16, 2024

TUESDAY, Jan. 16, 2024 -- Magnetic zaps to the brain can significantly help people with severe depression, if the procedure is guided using MRI brain scans, a new clinical trial has concluded.On average, patients showed substantial improvements in.

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Clinical Trials Trials 111

Science Daily: Pharmacology News

JANUARY 16, 2024

A study exploring the mechanisms behind why cognitive performance improves in response to exercise, has found that dopamine plays a key role.

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Drug Patent Watch

JANUARY 16, 2024

A recent article published in the Journal of Cheminformatics addresses the challenge of confirming the patent status of newly developed compounds, particularly in the pharmaceutical industry, where generating novel structures… The post An AI Approach to Generate Novel Pharmaceuticals using Patent Data appeared first on DrugPatentWatch - Make Better Decisions.

Pharmaceuticals 101

Pharmaceuticals 101

Drugs.com

JANUARY 16, 2024

TUESDAY, Jan. 16, 2024 -- There’s no link at all between weed use and a person’s use of illicit opioids, one way or the other, a new review concludes.Cannabis isn’t a gateway drug that can spark a person’s desire to try narcotics, results.

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Drugs 98

Science Daily: Pharmacology News

JANUARY 16, 2024

A mouse study designed to shed light on memory loss in people who experience repeated head impacts, such as athletes, suggests the condition could potentially be reversed. The research in mice finds that amnesia and poor memory following head injury is due to inadequate reactivation of neurons involved in forming memories.

Research 101

Research 101

Drugs.com

JANUARY 16, 2024

TUESDAY, Jan. 16, 2024 -- Vaccination can protect young people -- particularly teenagers-- against long COVID, a new study finds.Records of more than 1 million U.S. kids showed that the COVID jab can effectively shield kids from long-term health.

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Vaccine 98

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

SCIENMAG: Medicine & Health

JANUARY 16, 2024

In early 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a highly contagious and pathogenic virus, made its alarming debut and quickly spread worldwide, causing the novel coronavirus (COVID-19) pandemic that threatened human health and public safety.

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Virus Hospitals 93

Drugs.com

JANUARY 16, 2024

TUESDAY, Jan. 16, 2024 -- Following two weeks of hospital care for complications from prostate cancer surgery, U.S. Defense Secretary Lloyd Austin has been released from Walter Reed National Military Medical Center, the Pentagon announced.

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Hospitals 98

SCIENMAG: Medicine & Health

JANUARY 16, 2024

St. Jude Children’s Research Hospital announces today that St. Jude Home Care LLC, a home health agency for the hospital’s patients, earned dual certifications in both pediatrics and home health from Community Health Accreditation Partners (CHAP), an independent, non-profit, accrediting body for home and community-based healthcare organizations. St.

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Hospitals Research 91

Drugs.com

JANUARY 16, 2024

TUESDAY, Jan. 16, 2024 -- Ever glance at your paycheck and wonder why your take-home pay is so much less than you’d expect?The rising cost of employer-sponsored health insurance is a major reason why, a new study argues.The cost of.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

SCIENMAG: Medicine & Health

JANUARY 16, 2024

The inner workings of the human brain are a gradually unraveling mystery and Dr. Richard Naud of the University of Ottawa’s Faculty of Medicine has led a highly compelling new study that brings us closer to answering these big questions.

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Drugs.com

JANUARY 16, 2024

TUESDAY, Jan. 16, 2024 (HeathDay News) -- Folks often feel more alert and savvy after a great workout, and dopamine might be the reason why.A small, new study by British and Japanese researchers found higher levels of the "feel good" brain.

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Research 97

SCIENMAG: Medicine & Health

JANUARY 16, 2024

Knowing a patient’s weight is necessary for many weight-based medications such as thrombolytics, anticoagulants and numerous cardiovascular medications. Scaling drugs to a patient’s weight prevents adverse events from overtreatment and treatment failure due to underdosing. Inaccurate weight estimations may lead to inaccurate drug doses, which could cause patient harm.

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Research Treatment Drugs 89

Science Daily: Pharmacology News

JANUARY 16, 2024

Scientists recently revealed the latest National Seismic Hazard Model, showing that nearly 75% of the United States could experience a damaging earthquake, emphasizing seismic hazards span a significant part of the country.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

SCIENMAG: Medicine & Health

JANUARY 16, 2024

Pumping over 100,000 times a day, the heart is a critical muscle needed to deliver oxygen and nutrients to our organs to sustain healthy bodily function. Unfortunately, heart failure affects an estimated 6.2 million people in the U.S. and a staggering 64 million worldwide. Credit: Medical University of South Carolina. Photograph by Sarah Pack.

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Trials Drugs 87

BioPharma Drive: Drug Pricing

JANUARY 16, 2024

Relationships with Speaker Bureau faculty are among the most important that a biopharmaceutical company nurtures.

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SCIENMAG: Medicine & Health

JANUARY 16, 2024

The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be condensed to fit inside the nucleus. DNA condensation is not random.

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Regulations DNA 84

BioPharma Drive: Drug Pricing

JANUARY 16, 2024

While investment remains lower than in other areas of drug R&D, executives and VCs speak of growing momentum for a field that’s been overlooked in the past.

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Research Drugs 86

Drug Channels

JANUARY 16, 2024

My recent Drug Channels Outlook 2024 webinar covered 12 key trends that will shape the commercial environment this year. The video excerpt below highlights my commentary on trend #2: the rapid growth of anti-obesity GLP-1 agonist drugs. As I explain, this growth will challenge payer and channel economics, while boosting profits for patient reimbursement hub businesses and pharmacy benefit managers (PBMs).

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Pharmacy Drugs Production 80

Science Daily: Pharmacology News

JANUARY 16, 2024

RNA is thought to have sparked the origin of life by self-copying. Researchers have now revealed the atomic structure of an 'RNA copy machine' through cryo-EM. This breakthrough sheds light on a primordial RNA world and fuels advancements in RNA nanotechnology and medicine.

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RNA Research 86

addgene Blog

JANUARY 16, 2024

Annotation of genes in immune cells typically involves the creation of germline knockout mice, which is time-consuming, as it only changes one gene at a time. CRISPR-based systems enable gene knockout in immune cells in a high-throughput manner, but these systems have not been widely employed in vivo. The CHIME and new X-CHIME systems, developed and deposited at Addgene by Arlene Sharpe’s lab , allow for wide deployment of in vivo gene knockout in immune systems.

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Science Daily: Pharmacology News

JANUARY 16, 2024

Neuroscientists have investigated whether playing violent video games leads to a reduction in human empathy. To do this, they had adult test subjects play a violent video game repeatedly over the course of an experiment lasting several weeks. Before and after, their empathic responses to the pain of another person were measured. It was found that the violent video game had no discernible effect on empathy and underlying brain activity.

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SCIENMAG: Medicine & Health

JANUARY 16, 2024

You may not know it, but cows share information every time they burp, moo, and chew that speaks volumes about their health and welfare. Credit: Photo by Madi Hahn for Virginia Tech.

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Drugs.com

JANUARY 16, 2024

TUESDAY, Jan. 16, 2024 -- As levels of nighttime artificial outdoor light rise, so do the odds for a leading cause of vision loss, age-related macular degeneration (AMD).South Korean researchers found that people living in areas of that country.

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Research 75

SCIENMAG: Medicine & Health

JANUARY 16, 2024

Staphylococcus aureus (SA) is an extremely common bacterial infection; about 30% of people have colonies of SA living in their nose. SA is often harmless, but it is also a leading cause of hospital-acquired and community-associated infections.

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Vaccine Hospitals 72

Perficient: Drug Development

JANUARY 16, 2024

Personalization (formerly known as Interaction Studio) is a tool that exists inside the Salesforce Marketing Cloud tenant. It is mostly used to help the customer improve the user experience through web, mobile, and email. The sitemap is the heart of personalization. A good sitemap code implementation can lead you to an understanding of: How the user interacts with your site How much time they spend on different pages Where they are going next Let’s look at this in a more relatable way to s

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Marketing Production 64

SCIENMAG: Medicine & Health

JANUARY 16, 2024

In a collaboration between the Fralin Biomedical Research Institute at VTC and Carilion Clinic, researchers learned that by preserving large superficial leg veins intended for coronary bypass grafting in a mixture of the anticoagulant heparin and blood, rather than heparin and saline, the veins were better protected from cell and tissue damage.

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Research Clinical Research 72

Perficient: Drug Development

JANUARY 16, 2024

For more than 25 years, we’ve grown our presence, our talent, our skills, and our global footprint so that we can continually provide critical Agile software development and delivery services to the world’s biggest brands. Last October, we proudly entered into an agreement to acquire SMEDIX, Inc. , a healthcare and life sciences software engineering firm based in San Diego, California, with European operations located in Cluj-Napoca, Romania.

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Engineering Science Compliance Production 64

BioPharma Drive: Drug Pricing

JANUARY 16, 2024

The restructuring adds to a wave of industry layoffs and makes the Californian biotech at least third this year to reduce its workforce by at least 50%.

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Drugs 67