Drug Discovery World
SEPTEMBER 17, 2024
DDW’s Megan Thomas looks at a day in the life of Liam Tremble, Principal Scientist at Poolbeg Pharma. 1. Where do you work, and can you tell us what you’re working on at the moment? I work at Poolbeg Pharma, where we are developing novel treatments for diseases with unmet medical needs and large addressable markets, with programmes in oncology, infectious diseases and endocrinology.
Science Daily: Pharmacology News
SEPTEMBER 17, 2024
Consuming moderate amounts of coffee and caffeine regularly may offer a protective effect against developing multiple cardiometabolic diseases, including type 2 diabetes, coronary heart disease and stroke, according to new research.
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Drug Discovery World
SEPTEMBER 17, 2024
The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week, DDW has opened registrations for its webinar ‘ The latest advancements driving neuroscience drug discovery research ’, so our news highlights focus on developments in neuroscience, including a novel drug that has been shown to reduce neuronal death, and a potential disease-modi
Science Daily: Pharmacology News
SEPTEMBER 17, 2024
On average, we spend three and a quarter hours a day looking at our phones. Cutting back this time by one hour a day is not only good for our mental health, but also helps us to feel happier and more motivated at work, new research suggests.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
SEPTEMBER 17, 2024
Dorte Gram, founder of Pila Pharma and a former Novo Nordisk researcher who identified the molecule that became semaglutide, the active ingredient in Ozempic and Wegovy, has raised 10 million SEK ($980,320) for a novel obesity-related study. The money will allow the company to study drug tolerance and the effects of the company’s molecule on obesity in a Phase IIa study.
BioPharma Drive: Drug Pricing
SEPTEMBER 17, 2024
Summary study results show Ascendis’ drug for achondroplasia could be competitive to BioMarin's Voxzogo, which is the foundation of the latter company's growth plans.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
SEPTEMBER 17, 2024
The FDA previously rejected patritumab deruxtecan over manufacturing issues. Tuesday's study data should boost the companies' case, however.
Drug Discovery World
SEPTEMBER 17, 2024
Janssen-Cilag has shared new data from the Phase Ib/II OrigAMI-1 study at the European Society of Medical Oncology (ESMO) 2024 Congress. The results show that amivantamab combined with chemotherapy demonstrated promising antitumour activity in patients with RAS/BRAF wild-type (WT) metastatic colorectal cancer (mCRC) who have not previously received anti-epidermal growth factor receptor (EGFR) therapy.
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- Millions more people will die annually from antibiotic-resistant infections over the next 25 years unless steps are taken to counter this growing health threat, a new study warns.The number of deaths linked to.
Drug Discovery World
SEPTEMBER 17, 2024
Scientists have developed two new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer’s disease, and improve symptoms of neurodegeneration in mice. They say this promising approach could also be applied in future to other brain disorders driven by protein aggregation inside cells, such as motor neuron disease, Huntington’s disease and Parkinson’s disease.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
SEPTEMBER 17, 2024
Van Gogh's brushstrokes in 'The Starry Night' create an illusion of sky movement so convincing it led researchers to wonder how closely it aligns with the physics of real skies. Marine sciences and fluid dynamics specialists analyzed the painting to uncover what they call the hidden turbulence in the artwork. They used brushstrokes to examine the shape, energy, and scaling of atmospheric characteristics of the otherwise invisible atmosphere and used the relative brightness of the varying paint c
Drug Discovery World
SEPTEMBER 17, 2024
Join DDW and Lonza for this free event ‘ Building advanced cell models for toxicity testing ’. The event will take place on 19 September at 3pm GMT / 4pm CET / 10am EST / 7am PST. Life sciences researchers need a host of tools to develop and test critical disease-treating drugs and therapies, from basic research to final product release. Primary cells, media, and reagents are all important for supporting preclinical and clinical pharmaceutical workflows for drug discovery and absorption, distrib
BioPharma Drive: Drug Pricing
SEPTEMBER 17, 2024
The funding will support mid-stage testing of a drug the company believes to have the potential to treat a range of neurodegenerative conditions.
Science Daily: Pharmacology News
SEPTEMBER 17, 2024
With the help of NASA's Hubble Space Telescope, an international team of scientists has found more black holes in the early universe than has previously been reported. The new result can help scientists understand how supermassive black holes were created.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- Most parents are placing their kids in harms’ way by moving them out of their car booster seat too soon, a new study warns.Four out of five parents moved their kid out of a booster seat before the child was big enough, a.
Science Daily: Pharmacology News
SEPTEMBER 17, 2024
Physicists on the CMS experiment announce the most elaborate mass measurement of a particle that is notoriously difficult to study and has captivated the physics community for decades.
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- Deprivation, neglect and abuse during childhood can increase a person’s long-term risk of health problems, a new study warns.“Stress is implicated in nine of the 10 leading causes of death in the United States today,” said.
Science Daily: Pharmacology News
SEPTEMBER 17, 2024
Watching for changes in Mars' orbit over time could be new way to detect passing dark matter, according to researchers.
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- That plastic wrap you find around the food you eat is far from benign: A new study shows that more than 3,600 chemicals leach into food during the packaging process.Of that number, 79 chemicals are known to cause cancer.
Collaborative Drug
SEPTEMBER 17, 2024
Create ELN Templates: Templates are a great way to provide organization and uniformity to ELN entries, saving users time and ensuring data is easily digestible. Once an entry is ready to become a template, your Vault Administrator can publish it by clicking the template icon at the top of the page. Provide a name, decide which specific ELN fields should be included and whether to make them required or optional.
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- Counties and states where jails and prisons are packed are more likely to have higher rates of cancer, new research shows.“These results aren’t surprising. Incarceration in the U.S. is recognized as a key element of soc.
Broad Institute
SEPTEMBER 17, 2024
#WhyIScienceQ&A: A data scientist helps researchers solve computational problems By Ari Navetta September 17, 2024 Breadcrumb Home #WhyIScienceQ&A: A data scientist helps researchers solve computational problems Former nuclear physicist Edana Martin talks about the importance of collaboration and creative thinking in her work supporting researchers.
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- A few cups of coffee each morning can help protect a person against heart disease, stroke and type 2 diabetes, a new study says.Drinking three cups of coffee a day -- or about 200 to 300 milligrams of caffeine -- lowered.
Drug Patent Watch
SEPTEMBER 17, 2024
Enhancing Your Product Portfolio with CDMOs: A Strategic Partnership for Pharmaceutical Success The pharmaceutical industry is constantly evolving, driven by advancements in technology, innovations in product development, and the need for efficient manufacturing processes.
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- A small clinical trial suggests that a duo of drugs can extend survival for people battling advanced kidney cancer.Researchers at Roswell Park Comprehensive Cancer Center in Buffalo, N.Y., developed the new regimen, a.
addgene Blog
SEPTEMBER 17, 2024
Western blots can be tricky to get right. If you’ve thoughtfully done the technical design of your blot, but are still finding yourself having issues, you’re in the right place! In this post, we’ll talk about western blot optimization and troubleshooting.
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- Brain training aimed at improving memory can ward off symptoms of Alzheimer’s disease for years, a new study claims.Seniors experienced a slower decline in their memory and thinking abilities after undergoing brain t.
BioPharma Drive: Drug Pricing
SEPTEMBER 17, 2024
Backed by Bristol Myers Squibb, Ratio Therapeutics has a front row seat to the pharmaceutical industry’s pivot into the field of targeted radiation drugs.
Perficient: Drug Development
SEPTEMBER 17, 2024
In this blog post, we’ll develop a Custom Select Picker using Vue.js, TypeScript, and jQuery. This article will teach you how to use Vue.js to create a custom select-picker component. Select-pickers are adaptable user interface elements that let users select from a list of alternatives in numerous ways. We’ll improve this component by adding more features like “Apply” and “Cancel” buttons to provide users with more control over their choices.
Drugs.com
SEPTEMBER 17, 2024
TUESDAY, Sept. 17, 2024 -- As wildfires continue to burn across parts of California, a new study finds that smoke from these blazes and other air pollution could be harming kids’ mental health.Repeated exposure to high levels of particle pollution i.
Perficient: Drug Development
SEPTEMBER 17, 2024
Lazy loading should be considered for large applications with numerous routes. Sometimes, optimizing performance may risk delivering a better user experience. Using the technique known as “lazy loading,” the browser loads only the modules or parts that are required for the particular scenario. All the modules will not be loaded except the active route.
Drug Channels
SEPTEMBER 17, 2024
On October 8, 2024, Drug Channels Institute will release our 2024-25 Economic Report on Pharmaceutical Wholesalers and Specialty Distributors. This report—our fifteenth edition—remains the most comprehensive, fact-based tool for understanding and analyzing the large and growing U.S. pharmaceutical distribution industry. 9 chapters, 350+ pages, 178 exhibits, 750+ endnotes: There is nothing else available that comes close to this valuable resource.
Perficient: Drug Development
SEPTEMBER 17, 2024
In this installment of the UX in Universal Design Series , we focus on the transformative impact that Universal Design and accessible healthcare have on patient experience and health outcomes. By integrating Universal Design principles and focusing on usability, health systems can create inclusive environments that meet the needs of all patients, particularly those with physical disabilities.
Science Daily: Pharmacology News
SEPTEMBER 17, 2024
A species of semi-aquatic lizard produces a special bubble over its nostrils to breathe underwater and avoid predators.
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