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WEDNESDAY, March 12, 2025 -- The number of children poisoned through exposure to fentanyl, a powerful synthetic opioid, has skyrocketed in recent years, researchers have reported.Fentanyl poisonings increased by 924% among children 12 and younger.
Researchers have announced the creation of the first operating system designed for quantum networks: QNodeOS. The research marks a major step forward in transforming quantum networking from a theoretical concept to a practical technology that could revolutionize the future of the internet.
WEDNESDAY, March 12, 2025 -- A group of former U.S. Centers for Disease Control and Prevention (CDC) employees is fighting to get their jobs back after being abruptly laid off last month. In a letter sent Monday to Health and Human Services (HHS).
Climate change may lead to more precipitation and more intense floods. A new study shows that to understand the details of this relationship, it is important to distinguish between different types of rainfall and flood events -- namely, between short-term events that occur on a time scale of hours, and longer-term events that last several days. In each case, climate change has a different impact.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
WEDNESDAY, March 12, 2025 -- The nation's top health official, Robert F. Kennedy Jr., is taking steps to tighten oversight of chemicals in the U.S. food supply, a key component of his Make America Healthy Again agenda.On March 10, Kennedy dir.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
WEDNESDAY, March 12, 2025 -- Only 17 percent of adults say they want to see Medicaid funding decreased, while 42 percent think funding should increase and 40 percent think it should be kept about the same, according to results of the February 2025.
Funded by investors such as Flagship and General Catalyst, the AI startup claims its platform will help scientists speed up the experimentation process.
WEDNESDAY, March 12, 2025 -- Love pickleball, but facing a knee or hip replacement?Odds are youll return to the court in no time, a new study suggests.More than 7 of 10 regular pickleball players pick up their paddle promptly following joint r.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
WEDNESDAY, March 12, 2025 -- Knee or hip replacement is a major surgery, and many people must lean hard on their spouses to care for them during weeks to months of recuperation.But all that hassle is absolutely worthwhile for the one providing care.
WEDNESDAY, March 12, 2025 -- Kids are more likely to maintain a healthy weight if their parents adopt a responsive style while theyre babies and toddlers, a new study suggests.Children had a significantly lower average body mass index (BMI) t.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
WEDNESDAY, March 12, 2025 -- Purposeful splishing and splashing can help you trim your waist size and drop excess pounds, a new evidence review has concluded.Water aerobics led to about 6 pounds of weight loss and more than an inch off the waists.
We have discovered a novel non-covalent MurA inhibitor as an antibacterial agent through machine learning and bioactivity testing. This is the first to use machine learning for virtual screening of non-covalent inhibitors of MurA. ABSTRACT The bacterial cell wall is crucial for maintaining the integrity of bacterial cells. UDP-N-acetylglucosamine 1-carboxyethylene transferase (MurA) is an important enzyme involved in bacterial cell wall synthesis.
WEDNESDAY, March 12, 2025 -- Well-to-do and better-educated Americans have far lower rates of heart disease than the rest of the population, a new study says.The top 20% of high-income, college-educated Americans have less heart disease risk than.
New technology puts a spatial lens on CRISPR screening By Leah Eisenstadt March 12, 2025 Breadcrumb Home New technology puts a spatial lens on CRISPR screening Perturb-FISH reveals impacts of perturbations on gene expression and phenotype with single-cell, spatial resolution, allowing study of effects within and between cells. By Leah Eisenstadt March 12, 2025 Credit: Broad Communications Scientists in the Spatial Technology Platform at the Broad develop, use, and share spatial -omics approaches
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Intro In this post, we’ll take a look at a couple Sitecore SDKs commonly used to build XM Cloud head applications. Specifically, we’ll be looking at how to disable cookies used by these SDKs. This can be useful for data privacy and/or regulatory compliance reasons. These SDKs allow your application to integrate with other composable Sitecore services like analytics, personalization, and search.
When a pharmaceutical company completes clinical trials and prepares to launch a medical product, the focus often shifts to regulatory approvals, market access, and commercialization. However, one crucial aspect that must not be overlooked is Medical Information (MI) the vital bridge between pharmaceutical companies and healthcare professionals (HCPs) or patients.
Large, undisturbed forests are better for harboring biodiversity than fragmented landscapes, according to recent research. Ecologists agree that habitat loss and the fragmentation of forests reduces biodiversity in the remaining fragments. But ecologists don't agree whether it's better to focus on preserving many smaller, fragmented tracts of land or larger, continuous landscapes.
This study first employed molecular docking to identify potential allosteric inhibitors of PBP2a from FDA-approved drugs. Subsequent invitro experiments demonstrated that these identified inhibitors, when combined with cefazolin, synergistically enhanced the killing of methicillin-resistant Staphylococcus aureus (MRSA), effectively restoring MRSA's sensitivity to cefazolin.
The American Conference Institutes 21st Annual Paragraph IV Disputes is scheduled to take place from April 29-30, 2025 at The Altman Building in New York, NY. Widely recognized as the industry gold standard, the conference unites leaders from brand-name and generic drug companies, alongside federal judges, the U.S. PTOs PTAB, the FTC, and the FDA, to tackle the critical legal, regulatory, and business issues shaping pharmaceutical patent litigation.
The study outlines the design and synthesis of 25 pyrrolidinodiazenyl chalcones using covalent bitherapy to explore their potential invitro blood stage antimalarial activity against the mixed-blood stage culture (ring, trophozoites, and schizonts) of Plasmodium falciparum 3D7. ABSTRACT Malaria is a pervasive and deadly threat to the global population, and the resources available to treat this disease are limited.
SFTP? Isn’t that old? It is an oldie, but a goodie. With Data Cloud we can send data to a lot of external data sources like Marketing Cloud Engagement or Amazon S3 through Activation Targets. But there are times we are working with a destination system like Eloqua or Marketo that has solid support for SFTP. SFTP and Data Cloud work well together!
This study validated the therapeutic potential of moscatilin for renal clear cell carcinoma by combining network pharmacology methods and invitro experiments. ABSTRACT Moscatilin, a biphenyl compound derived from Dendrobium nobile , exhibits significant anti-tumor activity. However, the specific role of moscatilin in clear cell renal cell carcinoma (ccRCC) and its underlying molecular mechanisms have not been fully studied.
The Unseen Heroes of Generic Drugs: Stability Testing 101 As a consumer, have you ever stopped to think about the rigorous process that goes into bringing a generic version of your favorite medication to market? It's not just a matter of copying a formula and slapping a new label on it. Behind the scenes, generic drug manufacturers are working tirelessly to ensure that their products are safe, effective, and identical to their branded counterparts.
SFTP? Isn’t that old? It is an oldie but a goodie. With Data Cloud we can send data to a lot of external data sources like Marketing Cloud Engagement or Amazon S3 through Activation Targets. But there are times we are working with a destination system like Eloqua or Marketo that has solid support for SFTP. Even with Marketing Cloud Engagement you might want to get data flowing into Automation Studio instead of pushing directly to a Data Extension or Journey.
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