Drug Discovery World
APRIL 18, 2024
For the first time, a controlled human infection model for tuberculosis (TB) has been developed and could help with the future development of TB vaccines. Researchers from the University of Oxford developed the infection model, which replicates how TB enters the body by infecting people via the lung, using the bacille Calmette-Guerin (BCG) vaccine delivered via aerosol into participants’ lungs.
Science Daily: Pharmacology News
APRIL 18, 2024
Land subsidence is overlooked as a hazard in cities, according to new research. Scientists used satellite data that accurately and consistently maps land movement across China.
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Drug Discovery World
APRIL 18, 2024
Positive results have been announced by GSK for its antibiotic targeting uncomplicated urogenital gonorrhoea (GC) in adolescents and adults. First results from the EAGLE-1 Phase III trial for gepotidacin show that two oral doses of the antibiotic displayed superior success rates (92.6%) when compared to the combination treatment of ceftriaxone and oral azithromycin, which saw a 91.2% success rate.
BioPharma Drive: Drug Pricing
APRIL 18, 2024
It’s “early innings” in the obesity drug race, said Metsera CEO Clive Meanwell, whose company has acquired a portfolio of medicines it aims to test in combination.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
APRIL 18, 2024
Join DDW for this free event, ‘ Higher throughput bioanalytical methods accelerate the development and evaluation of advanced biotherapeutics ’, which is supported by Revvity. It will take place on 2 May at 3pm BST, 10am EDT, 4pm CEST and will be presented by Ron Morena, Manager in Analytical Bioassay at Tanvex Biopharma CDMO, along with and Dr Neha Mishra, Senior Scientist in the BioProduction R&D team, Revvity.
BioPharma Drive: Drug Pricing
APRIL 18, 2024
The start of a so-called rolling review formally begins an FDA evaluation of a closely watched drug that’s important to the biotech’s future, but faces questions about its sales potential.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
APRIL 18, 2024
Analysts had low expectations for Cerevel’s drug tavapadon, which was something of an afterthought in AbbVie’s proposed buyout of the biotech.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- Antipsychotics can substantially increase dementia patients’ risk of many serious health problems, a new study warns.
BioPharma Drive: Drug Pricing
APRIL 18, 2024
Company head Anne Wojcicki is considering buying all outstanding shares of the DNA testing firm, which has seen its stock slump in recent years.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- A combo of an allergy drug and a blood pressure med appears to lower daily drinking in folks battling severe alcoholism, French researchers report.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
APRIL 18, 2024
A new robotic suction cup which can grasp rough, curved and heavy stone, has been developed by scientists.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- Nearly 20% of fresh, frozen and canned fruits and vegetables that Americans eat contain concerning levels of pesticides, a new report finds.
Covalent Modifiers
APRIL 18, 2024
Tonia Kirschner, Matthias P. Müller, and Daniel Rauh Journal of Medicinal Chemistry 2024 DOI: 10.1021/acs.jmedchem.3c02403 The GTPase KRAS acts as a switch in cellular signaling, transitioning between inactive GDP-bound and active GTP-bound states. In about 20% of human cancers, oncogenic RAS mutations disrupt this balance, favoring the active form and promoting proliferative signaling, thus rendering KRAS an appealing target for precision medicine in oncology.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- Fresh organic basil tainted with salmonella and sold by Trader Joe's in 29 states has sickened at least 12 people, according to an alert issued Wednesday by the U.S. Centers for Disease Control and Prevention. One.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
addgene Blog
APRIL 18, 2024
As we celebrate twenty years at Addgene, we are sharing stories of our repository’s positive impact on science and scientists around the globe. Our first story focuses on a technology that has changed virtually all of biology…CRISPR.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- AI could help doctors cut back on the bewildering variety of medications that seniors frequently are prescribed, a new study suggests.More than 40% of seniors are prescribed five or more meds, and this increases a.
PLOS: DNA Science
APRIL 18, 2024
Clues to combatting a devastating disease can come from identifying people who have gene variants – mutations – that protect them, by slowing the illness or lowering the risk that it develops in the first place. Understanding how they do this may inspire treatment strategies for the wider patient population. Rare variants of three well-studied genes appear to delay inherited forms of Alzheimer’s disease – by decades.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- As climate change threatens another long hot summer for Americans, new data shows last summer's record-breaking temperatures sent a rising number of people to emergency departments. At special risk of heatstroke and.
Fierce BioTech
APRIL 18, 2024
In today’s fiercely competitive biotech industry, managing tight margins and evolving regulatory environments present major challenges. | NSF TraQtion software combines decades of quality expertise with real-time digital insight in one trusted, cloud-based digital solution.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- Deep-seated racial and ethnic disparities persist in health care across the United States, even in states considered the most progressive, a new report shows.For example, California received a score of 45 for the care.
Drug Patent Watch
APRIL 18, 2024
Annual Drug Patent Expirations for EVEKEO+ODT Evekeo Odt is a drug marketed by Azurity and is included in one NDA. There are four patents protecting this drug.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- A newly developed at-home urine test could potentially help doctors catch head and neck cancers earlier, a new study suggests.The test looks for tiny DNA fragments sloughed off by tumor cells, which pass from the.
Drug Patent Watch
APRIL 18, 2024
Annual Drug Patent Expirations for MYFEMBREE Myfembree is a drug marketed by Myovant Sciences and is included in one NDA. It is available from one supplier.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- When prostate cancer strikes, one question is paramount: Is it aggressive and requiring immediate treatment, or slow-growing and worthy of monitoring only?Right now, an invasive biopsy is the only way to answer that.
Drug Patent Watch
APRIL 18, 2024
Annual Drug Patent Expirations for VEMLIDY Vemlidy is a drug marketed by Gilead Sciences Inc and is included in one NDA. It is available from one supplier.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- Teenagers are frequently bullied about their weight on social media, and the bullying increases with each hour they spend on these sites, a new study reveals.Nearly one in five teens (17%) said they’d experienced.
Drug Patent Watch
APRIL 18, 2024
Annual Drug Patent Expirations for ZEPBOUND Zepbound is a drug marketed by Eli Lilly And Co and is included in one NDA. It is available from one supplier.
Drugs.com
APRIL 18, 2024
THURSDAY, April 18, 2024 -- Jobs that challenge your mind could help your brain age more gracefully, a new study suggests.
Drug Patent Watch
APRIL 18, 2024
Annual Drug Patent Expirations for ELIGARD+KIT Eligard Kit is a drug marketed by Tolmar and is included in four NDAs. It is available from one supplier.
Broad Institute
APRIL 18, 2024
Advisory Committee By Rose Circeo April 18, 2024 Breadcrumb Home Machine Learning in Drug Discovery Symposium Advisory Committee Anne Carpenter Anne Carpenter is senior director of the Imaging Platform at Broad Institute of MIT and Harvard, where she is also an institute scientist. Learn more. Pat Walters Pat Walters is chief data officer at Relay Therapeutics.
Drug Patent Watch
APRIL 18, 2024
Annual Drug Patent Expirations for FENSOLVI+KIT Fensolvi Kit is a drug marketed by Tolmar and is included in one NDA. It is available from one supplier.
Broad Institute
APRIL 18, 2024
Agenda By Rose Circeo April 18, 2024 Breadcrumb Home Machine Learning in Drug Discovery Symposium Agenda 08:00 - 08:50 am Registration/breakfast 08:50 - 09:00 AM Opening Remarks Keynote 09:00 - 10:00 am Jennifer Listgarten Professor University of California, Berkeley Morning session 10:00 - 10:40 am Broad talk 10:40 - 11:00 am Break and poster viewing 11:00 - 11:40 am Broad talk 11:40 - 12:00 noon TBD, Lightning talks from selected poster presenters 12:00 - 1:30 pm Lunch and poster v
Drug Patent Watch
APRIL 18, 2024
Annual Drug Patent Expirations for FOTIVDA Fotivda is a drug marketed by Aveo Pharms and is included in one NDA. It is available from one supplier.
ProRelix Research
APRIL 18, 2024
According to the National Cancer Institute (NCI), a solid tumour is a mass of tissue that usually does not contain cysts or liquid areas such as sarcomas (arising from connective […] The post The Promise of Clinical Trials in Advancing Solid Tumour Cancer Treatments appeared first on ProRelix Research.
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