Thu.Jul 11, 2024

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Pfizer thinks it found its obesity pill

BioPharma Drive: Drug Pricing

Far behind companies like Novo and Eli Lilly, Pfizer hopes the version of the drug, danuglipron, that it’s chosen to advance can break into the ultra-lucrative market for weight-loss medicines.

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Hydrogen flight looks ready for take-off with new advances

Science Daily: Pharmacology News

The possibility of hydrogen-powered flight means greater opportunities for fossil-free travel, and the technological advances to make this happen are moving fast. New studies show that almost all air travel within a 750-mile radius (1200 km) could be made with hydrogen-powered aircraft by 2045, and with a novel heat exchanger currently in development, this range could be even further.

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Only 1 in 4 Still Taking Ozempic, Wegovy for Weight Loss Two Years Later

Drugs.com

THURSDAY, July 11, 2024 -- Three of four patients stop taking Ozempic or Wegovy two years after being prescribed the blockbuster drugs for weight loss, a new analysis shows.Conducted by Prime Therapeutics and Magellan Rx Management (MRx), the.

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First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin

Science Daily: Pharmacology News

An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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How to get into a clinical trial? Understanding inclusion and exclusion criteria

Antidote

When determining which clinical trial is the right fit , many factors must be considered. The site location, the number of required visits, and the length of the study are all important considerations, but before any of this, it is vital to consider the study's inclusion and exclusion criteria.

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'A history of contact': Geneticists are rewriting the narrative of Neanderthals and other ancient humans

Science Daily: Pharmacology News

Using genomes from 2,000 living humans as well as three Neanderthals and one Denisovan, an international team mapped the gene flow between the hominin groups over the past quarter-million years.

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Dark matter in dwarf galaxy tracked using stellar motions

Science Daily: Pharmacology News

The qualities and behavior of dark matter, the invisible 'glue' of the universe, continue to be shrouded in mystery. Though galaxies are mostly made of dark matter, understanding how it is distributed within a galaxy offers clues to what this substance is, and how it's relevant to a galaxy's evolution.

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New Research Points Towards Potential Treatment for Anorexia

Drugs.com

THURSDAY, July 11, 2024 -- Anorexia nervosa could be caused by lack of a specific brain chemical, reports a research team that has developed a possible cure for the eating disorder.Mouse studies have revealed that a deficit in acetycholine, a.

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A stealth fungus has decimated North American bats but scientists may be a step closer to treating white-nose syndrome

Science Daily: Pharmacology News

An invasive fungus that colonizes the skin of hibernating bats with deadly consequences is a stealthy invader that uses multiple strategies to slip into the small mammals' skin cells and quietly manipulate them to aid its own survival. The fungus, which causes the disease white-nose syndrome, has devastated several North American species over the last 18 years.

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FDA’s lab-developed test rule could be first test of agency’s power post-Chevron

BioPharma Drive: Drug Pricing

The Supreme Court’s decision to overturn the Chevron doctrine would make it easier to challenge agency regulations, such as the LDT final rule.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Forest carbon storage has declined across much of the Western U.S., likely due to drought and fire

Science Daily: Pharmacology News

Forests have been embraced as a natural climate solution, due to their ability to soak up carbon dioxide from the atmosphere as they grow, locking it up in their trunks, branches, leaves, and roots. But a new study confirms widespread doubts about the potential for most forests in the Western US to help curb climate change. The paper analyzed trends in carbon storage across the American West from 2005 to 2019.

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New Type of Brain Stimulation Could Shorten Treatment Time for Bipolar Disorder

Drugs.com

THURSDAY, July 11, 2024 -- Powerful magnetic stimulation can help treat people with bipolar disorder, according to results from a small trial.The therapy, called accelerated intermittent theta burst stimulation, involves magnetic waves delivered to.

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Muscle machine: How water controls the speed of muscle contraction

Science Daily: Pharmacology News

The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study.

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Know a Narcissist? They May Become Less So as They Age

Drugs.com

THURSDAY, July 11, 2024 -- Your schoolmate who acted like he was better than everyone else has probably shed some of that narcissistic behavior an adult. New research shows people tend to be less narcissistic as they age. Still, those who were more.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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CDMO Value Proposition: Why It Matters

Drug Patent Watch

The value proposition of Contract Development and Manufacturing Organizations (CDMOs) has become increasingly crucial in the pharmaceutical industry.

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Women With Fibroids Often Offered Hysterectomy Over Less Invasive Treatment

Drugs.com

THURSDAY, July 11, 2024 -- Women with uterine fibroids are often told hysterectomy is the best treatment, even though less invasive options are available, a new study finds.More than half (53%) of women with uterine fibroids -- non-cancerous.

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Biosimilar Patent Dance: Leveraging PTAB Challenges for Strategic Advantage

Drug Patent Watch

In the high-stakes world of biosimilar development, manufacturers are increasingly turning to an unexpected partner: the Patent Trial and Appeal […] Source

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Survey Shows Loneliness Haunts Over 1 in 5 People

Drugs.com

THURSDAY, July 11, 2024 -- Loneliness strikes more than a fifth of people worldwide, a new survey warns.In the Gallup survey published Wednesday, 23% of people said they felt lonely "a lot of the previous day." Those experiencing feelings of.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Targeted drug treatment leads tumor cells to imitate viral infection

Broad Institute

Targeted drug treatment leads tumor cells to imitate viral infection By Ari Navetta July 11, 2024 Breadcrumb Home Targeted drug treatment leads tumor cells to imitate viral infection Exploiting "viral mimicry," mIDH1 inhibitors trick tumors into thinking they are infected with a virus. By Ari Navetta July 11, 2024 Credit: Ricardo Job-Reese, Broad Communications A graphic showing a virus trapped behind a lock wrapped in spider webs, beside a pill with a key inside Related people Robert Manguso Re

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Trained Peers as Good as Social Workers at Preventing Opioid Overdoses

Drugs.com

THURSDAY, July 11, 2024 -- Support provided by someone who has personally lived with addiction is an effective way to follow-up with ER patients after an opioid overdose, new research shows.Patients who have had a non-fatal overdose are at great.

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Novo’s once-weekly insulin rejected by FDA

BioPharma Drive: Drug Pricing

The FDA’s decision to turn back the drugmaker’s new insulin product narrows Novo’s lead in the U.S. over Eli Lilly, which has a similar diabetes treatment in late-stage testing.

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At Least 58 Have Now Been Sickened After Eating Diamond Shruumz Edibles

Drugs.com

THURSDAY, July 11, 2024 -- Nearly 60 illnesses, including 30 hospitalizations, have now been linked to eating Diamond Shruumz edibles, U.S. health officials reported.The U.S. Centers for Disease Control and Prevention noted in an update issued.

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AI in Drug Discovery: The Role of SHAP in Pharmacology

Reprocell

In recent years, artificial intelligence (AI) and machine learning have become integral to the field of pharmacology, revolutionizing how we approach drug discovery, diagnosis, and treatment pathways. As AI's influence grows, so does the necessity for transparency in its decision-making processes. This is where explainable AI comes into play, providing a crucial bridge between advanced computational models and human understanding.

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Could an App Help Predict Thinking Declines for Those With Alzheimer's?

Drugs.com

THURSDAY, July 11, 2024 -- Dutch researchers are developing an app to predict how individual cases of Alzheimer's disease will progress.Based on data from nearly 1,000 Alzheimer's patients, they have already developed a prediction model that can.

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Which pharmaceutical companies have the most drug patents in Sweden?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Sweden. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

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The path to perfection: A deep dive into continuous improvement in quality management

DS in Pharmatics

What principle does DSI prioritize for continuous improvement for quality management? How do these principles contribute to the advancement of quality management systems? Continuous improvement is an industry expectation.

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New tentative approval for Alembic drug dabigatran etexilate mesylate

Drug Patent Watch

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.

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Salesforce Marketing Cloud Summer Release Updates ’24

Perficient: Drug Development

Salesforce successfully pushed the next set of new feature updates, and these updates started rolling from June 7 th and was expected to complete by June 28 th. If you’re unable to see any of the below listed features, please reach out to your account executive to have additional information. The Top 5 Feature Releases Were – Automation History Dashboard In addition to Overview, and Activities tab under Automation Studio, you should now see a new tab named “History” which would have an intuitive

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New patent for Arcutis drug ZORYVE

Drug Patent Watch

Annual Drug Patent Expirations for ZORYVE Zoryve is a drug marketed by Arcutis and is included in two NDAs. It is available from one supplier. There are seven patents protecting this drug.

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Perficient Included in Two Commerce-Focused IDC Market Glances

Perficient: Drug Development

In today’s ever-evolving digital landscape, a one-size-fits-all commerce solution has become obsolete. The e-commerce market is more diverse and complex than ever, with businesses facing the challenge of navigating an array of software options, from AI-powered personalization engines to blockchain-based payment systems. As the industry continues its rapid shift towards composable commerce architectures, microservices, and API-first platforms, digital commerce vendors must not only adapt th

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New patent for Bristol drug AUGTYRO

Drug Patent Watch

Annual Drug Patent Expirations for AUGTYRO Augtyro is a drug marketed by Bristol and is included in one NDA. It is available from one supplier. There are three patents protecting this drug.

Drugs 59
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Sleep Apnea Raises Chances of Heart Disease, Particularly in Young Adults

Drugs.com

THURSDAY, July 11, 2024 -- Sleep apnea is particularly dangerous for the heart health of young adults, even more so than in older folks, a new study warns.The link between sleep apnea and risk factors for heart disease is stronger in people between.

Disease 52
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New patent for Vanda Pharms drug HETLIOZ LQ

Drug Patent Watch

Annual Drug Patent Expirations for HETLIOZ+LQ Hetlioz Lq is a drug marketed by Vanda Pharms Inc and is included in one NDA. It is available from one supplier.

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