Drug Discovery World
JULY 11, 2024
Evotec and Pfizer have entered into a multi-year research collaboration, initially focused on early discovery research for metabolic and infectious diseases. The research will be carried out at Evotec’s sites in France, including Campus Curie in Toulouse with capabilities spanning high throughput screening, in vitro and in vivo biology, proteomics and metabolomics.
BioPharma Drive: Drug Pricing
JULY 11, 2024
Far behind companies like Novo and Eli Lilly, Pfizer hopes the version of the drug, danuglipron, that it’s chosen to advance can break into the ultra-lucrative market for weight-loss medicines.
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Drug Discovery World
JULY 11, 2024
Closed Loop Medicine has joined the NVIDIA Inception accelerator programme, designed to nurture start-ups and early-stage companies revolutionising industries with technological advancements. The programme supports all stages of a start-up’s life cycle, providing access to the latest tools, expertise, and a network of venture capitalist investors, to accelerate solution development and business growth.
Science Daily: Pharmacology News
JULY 11, 2024
The possibility of hydrogen-powered flight means greater opportunities for fossil-free travel, and the technological advances to make this happen are moving fast. New studies show that almost all air travel within a 750-mile radius (1200 km) could be made with hydrogen-powered aircraft by 2045, and with a novel heat exchanger currently in development, this range could be even further.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
JULY 11, 2024
DDW’s Megan Thomas talks to Ali Tavassoli, Chief Scientific Officer of Curve Therapeutics and Professor of Chemical Biology at the University of Southampton, UK. MT: Where do you work, and can you tell us what you’re working on at the moment? AT: We spun Curve out of my academic group five years ago to commercialise a genetically-encoded high throughput screening platform that allows the generation and screening of libraries of millions of cyclic peptides inside mammalian cells.
Science Daily: Pharmacology News
JULY 11, 2024
Using genomes from 2,000 living humans as well as three Neanderthals and one Denisovan, an international team mapped the gene flow between the hominin groups over the past quarter-million years.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
JULY 11, 2024
An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted.
Antidote
JULY 11, 2024
When determining which clinical trial is the right fit , many factors must be considered. The site location, the number of required visits, and the length of the study are all important considerations, but before any of this, it is vital to consider the study's inclusion and exclusion criteria.
Science Daily: Pharmacology News
JULY 11, 2024
The qualities and behavior of dark matter, the invisible 'glue' of the universe, continue to be shrouded in mystery. Though galaxies are mostly made of dark matter, understanding how it is distributed within a galaxy offers clues to what this substance is, and how it's relevant to a galaxy's evolution.
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Three of four patients stop taking Ozempic or Wegovy two years after being prescribed the blockbuster drugs for weight loss, a new analysis shows.Conducted by Prime Therapeutics and Magellan Rx Management (MRx), the.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
JULY 11, 2024
An invasive fungus that colonizes the skin of hibernating bats with deadly consequences is a stealthy invader that uses multiple strategies to slip into the small mammals' skin cells and quietly manipulate them to aid its own survival. The fungus, which causes the disease white-nose syndrome, has devastated several North American species over the last 18 years.
Drug Patent Watch
JULY 11, 2024
The value proposition of Contract Development and Manufacturing Organizations (CDMOs) has become increasingly crucial in the pharmaceutical industry.
BioPharma Drive: Drug Pricing
JULY 11, 2024
The Supreme Court’s decision to overturn the Chevron doctrine would make it easier to challenge agency regulations, such as the LDT final rule.
Science Daily: Pharmacology News
JULY 11, 2024
Forests have been embraced as a natural climate solution, due to their ability to soak up carbon dioxide from the atmosphere as they grow, locking it up in their trunks, branches, leaves, and roots. But a new study confirms widespread doubts about the potential for most forests in the Western US to help curb climate change. The paper analyzed trends in carbon storage across the American West from 2005 to 2019.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Patent Watch
JULY 11, 2024
In the high-stakes world of biosimilar development, manufacturers are increasingly turning to an unexpected partner: the Patent Trial and Appeal […] Source
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Lupus is caused by a specific defect in the immune system that can be reversed, potentially curing the autoimmune disorder, a new study claims.The disease appears to be caused by malfunctions in an immune system pathway.
Science Daily: Pharmacology News
JULY 11, 2024
The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study.
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Powerful magnetic stimulation can help treat people with bipolar disorder, according to results from a small trial.The therapy, called accelerated intermittent theta burst stimulation, involves magnetic waves delivered to.
Broad Institute
JULY 11, 2024
Targeted drug treatment leads tumor cells to imitate viral infection By Ari Navetta July 11, 2024 Breadcrumb Home Targeted drug treatment leads tumor cells to imitate viral infection Exploiting "viral mimicry," mIDH1 inhibitors trick tumors into thinking they are infected with a virus. By Ari Navetta July 11, 2024 Credit: Ricardo Job-Reese, Broad Communications A graphic showing a virus trapped behind a lock wrapped in spider webs, beside a pill with a key inside Related people Robert Manguso Re
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Your schoolmate who acted like he was better than everyone else has probably shed some of that narcissistic behavior an adult. New research shows people tend to be less narcissistic as they age. Still, those who were more.
BioPharma Drive: Drug Pricing
JULY 11, 2024
The FDA’s decision to turn back the drugmaker’s new insulin product narrows Novo’s lead in the U.S. over Eli Lilly, which has a similar diabetes treatment in late-stage testing.
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Women with uterine fibroids are often told hysterectomy is the best treatment, even though less invasive options are available, a new study finds.More than half (53%) of women with uterine fibroids -- non-cancerous.
Reprocell
JULY 11, 2024
In recent years, artificial intelligence (AI) and machine learning have become integral to the field of pharmacology, revolutionizing how we approach drug discovery, diagnosis, and treatment pathways. As AI's influence grows, so does the necessity for transparency in its decision-making processes. This is where explainable AI comes into play, providing a crucial bridge between advanced computational models and human understanding.
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Loneliness strikes more than a fifth of people worldwide, a new survey warns.In the Gallup survey published Wednesday, 23% of people said they felt lonely "a lot of the previous day." Those experiencing feelings of.
Drug Patent Watch
JULY 11, 2024
Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Anorexia nervosa could be caused by lack of a specific brain chemical, reports a research team that has developed a possible cure for the eating disorder.Mouse studies have revealed that a deficit in acetycholine, a.
Drug Patent Watch
JULY 11, 2024
Annual Drug Patent Expirations for ZORYVE Zoryve is a drug marketed by Arcutis and is included in two NDAs. It is available from one supplier. There are seven patents protecting this drug.
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Support provided by someone who has personally lived with addiction is an effective way to follow-up with ER patients after an opioid overdose, new research shows.Patients who have had a non-fatal overdose are at great.
Drug Patent Watch
JULY 11, 2024
Annual Drug Patent Expirations for AUGTYRO Augtyro is a drug marketed by Bristol and is included in one NDA. It is available from one supplier. There are three patents protecting this drug.
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Nearly 60 illnesses, including 30 hospitalizations, have now been linked to eating Diamond Shruumz edibles, U.S. health officials reported.The U.S. Centers for Disease Control and Prevention noted in an update issued.
Drug Patent Watch
JULY 11, 2024
Annual Drug Patent Expirations for HETLIOZ+LQ Hetlioz Lq is a drug marketed by Vanda Pharms Inc and is included in one NDA. It is available from one supplier.
Drugs.com
JULY 11, 2024
THURSDAY, July 11, 2024 -- Dutch researchers are developing an app to predict how individual cases of Alzheimer's disease will progress.Based on data from nearly 1,000 Alzheimer's patients, they have already developed a prediction model that can.
Drug Patent Watch
JULY 11, 2024
Annual Drug Patent Expirations for HETLIOZ Hetlioz is a drug marketed by Vanda Pharms Inc and is included in two NDAs. It is available from one supplier.
DS in Pharmatics
JULY 11, 2024
What principle does DSI prioritize for continuous improvement for quality management? How do these principles contribute to the advancement of quality management systems? Continuous improvement is an industry expectation.
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