Thu.Dec 14, 2023

article thumbnail

Apellis eye drug likely to be rejected in Europe, company says

BioPharma Drive: Drug Pricing

According to Apellis executives, reviewers in Europe are skeptical of the benefits of its geographic atrophy medicine, Syfovre, and appear poised to recommend against approval at a meeting next month.

Drugs 124
article thumbnail

Diverse gut bacteria communities protect against harmful pathogens by nutrient blocking

Science Daily: Pharmacology News

New study demonstrates that diverse communities of resident bacteria can protect the human gut from disease-causing microorganisms. However, this protective effect is lost when only single species of gut bacteria are present. The researchers found that protective communities block the growth of harmful pathogens by consuming nutrients that the pathogen needs.

Disease 121
article thumbnail

Perfume from Extinct Flowers, Thanks to Ancient DNA and Synthetic Biology

PLOS: DNA Science

“Enchant your loved ones with nature’s lost scents, revived through biotechnology and perfume artistry.” When that popped up on Facebook, I was intrigued. So I clicked. “Meet Invisible Woods: a clean, refreshing scent revived from extinct flower DNA ,” beneath an image of “origin flower” Wendlandia angustifolia.

DNA 119
article thumbnail

'Long flu' has emerged as a consequence similar to long COVID

Science Daily: Pharmacology News

New research comparing the viruses that cause the flu and COVID-19 shows that people hospitalized with seasonal influenza also can suffer long-term, negative health effects, especially involving their lungs and airways. The study also found that in the 18 months after infection, patients hospitalized for either COVID-19 or seasonal influenza faced an increased risk of death, hospital readmission, and other health problems.

Hospitals 118
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Using CBD & Other Hemp Products? You're Not Alone, Study Finds

Drugs.com

THURSDAY, Dec. 14, 2023 -- The market for cannabidiol (CBD) and other products derived from the hemp plant is now wide open in the United States, but that could bring danger to consumers, the authors of a new report warn.Many people may not.

article thumbnail

Optimizely Configured Commerce – Customizing Elasticsearch v7 Index

Perficient: Drug Development

The Optimizely configured commerce introduces Elasticsearch v7 for a better search experience. In the dynamic landscape of the Commerce world, there is always room for extended code customization. Furthermore, Optimizely provides explicit steps to customize Elasticsearch v7 indexes. There are a lot of advantages to using Elasticsearch v7. some are Improved Performance Security Enhancements Elasticsearch SQL GeoJSON Support Usability and Developer-Friendly Features In this post, we will go throug

More Trending

article thumbnail

Too Often, Unlocked, Loaded Guns Are Fatal Playthings for America’s Children

Drugs.com

THURSDAY, Dec. 14, 2023 -- A loaded revolver left out on a nightstand, a curious child -- and unimaginable tragedy. Moments like this have occurred in American homes hundreds of times over the past two decades, killing 1,262 children, according to.

98
article thumbnail

NIH research identifies opportunities to improve future HIV vaccine candidates

SCIENMAG: Medicine & Health

WHAT: An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues.

Vaccine 95
article thumbnail

Irregular Sleep Is Tied to a Higher Odds for Dementia

Drugs.com

THURSDAY, Dec. 14, 2023 -- People who maintain a mostly regular sleep pattern could have a lower risk of developing dementia than those whose sleeping and waking times vary wildly, a new study finds.People with the most irregular sleep are 53% more.

98
article thumbnail

Researchers, Coast Salish people analyze 160-year-old indigenous dog pelt in the Smithsonian's collection

Science Daily: Pharmacology News

A new analysis sheds light on the ancestry and genetics of woolly dogs, a now extinct breed of dog that was a fixture of Indigenous Coast Salish communities in the Pacific Northwest for millennia. Anthropologists and biologists analyzed genetic clues preserved in the pelt of 'Mutton,' the only known woolly dog fleece in the world, to pinpoint the genes responsible for their highly sought-after woolly fur.

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Texting, Video Gaming Especially Bad for Teen's Sleep: Study

Drugs.com

THURSDAY, Dec. 14, 2023 -- Any type of time spent looking at screens before bed is bad for kids' sleep, but new research shows that "interactive" screen time -- texting and video games, for example -- is especially harmful.The effects of.

article thumbnail

Social distancing was more effective at preventing local COVID-19 transmission than international border closures

SCIENMAG: Medicine & Health

LA JOLLA, CA—Elucidating human contact networks could help predict and prevent the transmission of SARS-CoV-2 and future pandemic threats. A new study from Scripps Research scientists and collaborators points to which public health protocols worked to mitigate the spread of COVID-19—and which ones didn’t.

article thumbnail

More Research Shows the Brain Benefits of Exercise

Drugs.com

THURSDAY, Dec. 12, 2023 -- Regular exercise appears to enhance and even grow crucial areas of the human brain, new research using MRI scans shows. It's long been known that physical activity is a brain-booster, but this international study.

article thumbnail

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

SCIENMAG: Medicine & Health

New York, NY [December 14, 2023]—In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome. Credit: Stein et al.

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

This next generation blue light could potentially promote or hinder sleep on command

Science Daily: Pharmacology News

Blue light from LED lamps and consumer electronics can mess with your sleep because it disrupts production of the natural sleep hormone melatonin. Tinted glasses or displays in night mode can mask, but don't remove, a portion of the disruptive wavelengths. But now, researchers report that they have designed more 'human-centric' LEDs that could potentially enhance drowsiness or alertness on command.

article thumbnail

Finding the source of debilitating, body-wide muscular pain and weakness

SCIENMAG: Medicine & Health

Researchers from Tokyo Medical and Dental University (TMDU) identify the T cells that, when activated, are pathogenic in a subset of idiopathic inflammatory myopathies Credit: Department of Rheumatology, TMDU Researchers from Tokyo Medical and Dental University (TMDU) identify the T cells that, when activated, are pathogenic in a subset of idiopathic inflammatory myopathies Tokyo, Japan […]

article thumbnail

AI study reveals individuality of tongue's surface

Science Daily: Pharmacology News

Artificial Intelligence (AI) and 3D images of the human tongue have revealed that the surface of our tongues are unique to each of us, new findings suggest. The results offer an unprecedented insight into the biological make-up of our tongue's surface and how our sense of taste and touch differ from person to person.

93
article thumbnail

Improving treatment for opioid use disorder

SCIENMAG: Medicine & Health

In the fatal world of opioid use disorder (OUD), pharmacotherapy, or using a prescribed medication to treat drug dependence, has emerged as the gold standard of treatment. Among the trio of FDA-approved medications to treat OUD, buprenorphine is the newest highly effective drug that can suppress and reduce cravings for opioids.

article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Viking dentistry was surprisingly advanced

Science Daily: Pharmacology News

Widespread caries and toothache -- but also some dental work and filing of front teeth. Viking Age teeth from Varnhem bear witness to surprisingly advanced dentistry.

92
article thumbnail

Can an app improve your romantic relationship?

SCIENMAG: Medicine & Health

Half of all marriages in the United States are likely to fail by the time the spouses reach their 50s. Understandably, many couples are looking for ways to avoid becoming part of that statistic, well aware of a divorce’s possible wide-reaching detrimental effects on families, children, personal finances, individual well-being—and direct and indirect costs to society.

84
article thumbnail

Mothers and children have their birthday in the same month more often than you'd think -- and here's why

Science Daily: Pharmacology News

Do you celebrate your birthday in the same month as your mum? If so, you are not alone. The phenomenon occurs more commonly than expected -- a new study of millions of families has revealed.

83
article thumbnail

SNAP recipients may struggle to meet dietary goals, especially in food deserts

SCIENMAG: Medicine & Health

The Supplemental Nutrition Assistance Program (SNAP) is the nation’s largest nutrition program, helping 41 million participants afford “nutritious food essential to health and well-being.” Credit: University of Notre Dame/Barbara Johnston The Supplemental Nutrition Assistance Program (SNAP) is the nation’s largest nutrition program, helping 41 million participants afford “nutritious food essential to health and well-being.

84
article thumbnail

Astronomers discover first population of binary stripped stars

Science Daily: Pharmacology News

Astronomers have discovered a population of massive stars that have been stripped of their hydrogen envelopes by their companions in binary systems. The findings shed light on the hot helium stars that are believed to be the origins of hydrogen-poor core-collapse supernovae and neutron star mergers.

83
article thumbnail

Mount Sinai receives $1.3 million from the National Institutes of Health to support program that introduces high school students to virus surveillance

SCIENMAG: Medicine & Health

The Icahn School of Medicine at Mount Sinai has received more than $1.3 million from the National Institute of General Medical Sciences of the National Institutes of Health (NIH) to expand the New York City Virus Hunters program.

Virus 82
article thumbnail

Unexpected chemistry reveals cosmic star factories´ secrets

Science Daily: Pharmacology News

Two galaxies in the early universe, which contain extremely productive star factories, have been studied by a team of scientists. Using powerful telescopes to split the galaxies' light into individual colors, the scientists were amazed to discover light from many different molecules -- more than ever before at such distances. Studies like this could revolutionize our understanding of the lives of the most active galaxies when the universe was young, the researchers believe.

article thumbnail

Those Who Fear Serious Illness More Likely to Die Sooner: Study

Drugs.com

THURSDAY, Dec. 14, 2023 -- Having severe hypochondria can prompt hours of needless worrying, but in an ironic twist new research now shows it could also shorten your life.New Swedish research found people diagnosed with an excessive fear of serious.

article thumbnail

Recorded Webinar: Unlocking Potential Hits with an Advanced Deep Learning Methodology

Collaborative Drug

Discover breakthroughs in drug discovery with our recorded webinar. Susana Tomasio of CDD explores deep learning for similarity search in ChEMBL.

Drugs 85
article thumbnail

1 in 3 Men Open to Having More Than One Partner. Women, Not So Much

Drugs.com

THURSDAY, Dec. 14, 2023 -- Being in a marriage or long-term relationship typically includes promises of monogamy, but new research shows a surprising number of folks, mostly men, are open to the idea of having another person in the mix.Fully.

article thumbnail

Reaching for the (invisible) stars

Science Daily: Pharmacology News

Supernovae -- stellar explosions as bright as an entire galaxy -- have fascinated us since time immemorial. Yet, there are more hydrogen-poor supernovae than astrophysicists can explain. Now, scientists may have found the missing precursor star population.

76
article thumbnail

New Moderna cancer vaccine data spurs share rally

BioPharma Drive: Drug Pricing

Shares climbed by double digits after new evidence led to speculation among analysts that Moderna and partner Merck could seek an approval before completing Phase 3 testing.

Vaccine 67
article thumbnail

Can you change a chicken into a frog, a fish or a chameleon?

Science Daily: Pharmacology News

Researchers have developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo.

article thumbnail

Ancient DNA reveals how a chicken virus evolved to become more deadly

SCIENMAG: Medicine & Health

An international team of scientists led by geneticists and disease biologists from the University of Oxford and LMU Munich have used ancient DNA to trace the evolution of Marek’s Disease Virus (MDV). This global pathogen causes fatal infections in unvaccinated chickens and costs the poultry industry over $1 billion per year.

DNA 67
article thumbnail

New patent for Boehringer Ingelheim drug SYNJARDY XR

Drug Patent Watch

Annual Drug Patent Expirations for SYNJARDY+XR Synjardy Xr is a drug marketed by Boehringer Ingelheim and is included in one NDA. It is available from one supplier. There are seven… The post New patent for Boehringer Ingelheim drug SYNJARDY XR appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 59