Heart of Jovian moon's volcanic rage
Science Daily: Pharmacology News
DECEMBER 13, 2024
A new study points to why, and how, Io became the most volcanic body in the solar system.
Fri.Dec 13, 2024
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Eat Less Meat, More Beans & Lentils for Protein, New USDA Guidelines Say
Drugs.com
DECEMBER 13, 2024
FRIDAY, Dec. 13, 2024 -- Beans, peas and lentils take center stage in newly proposed changes to dietary guidelines for Americans. In a report released this week by an advisory committee to the Agriculture Department, experts suggest that the.
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New device produces critical fertilizer ingredient from thin air, cutting carbon emissions
Science Daily: Pharmacology News
DECEMBER 13, 2024
A new prototype device demonstrates an innovative approach to producing ammonia -- a key component of fertilizer -- that could transform an industry responsible for about one-third of global greenhouse gas emissions.
Reiki May Help Ease the Pain of Cancer Treatment
Drugs.com
DECEMBER 13, 2024
FRIDAY, Dec. 13, 2024 -- The ancient Japanese practice of reiki "energy healing" might help some cancer patients deal with the pain that can come with infusion therapies, new research shows. "Outpatients receiving reiki during infusion reported.
Bridging Innovation & Patient Care: The Growing Role of AI
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Planets form through domino effect
Science Daily: Pharmacology News
DECEMBER 13, 2024
New radio astronomy observations of a planetary system in the process of forming show that once the first planets form close to the central star, these planets can help shepherd the material to form new planets farther out. In this way each planet helps to form the next, like a line of falling dominos each triggering the next in turn.
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Astrophysicists capture astonishing images of gamma-ray flare from supermassive black hole M87
Science Daily: Pharmacology News
DECEMBER 13, 2024
The galaxy M87, located in the Virgo constellation, provided the first-ever photo of a black hole in 2019, when the Event Horizon Telescope captured an image of the supermassive black hole at the galaxy's center. An international research team has now observed a teraelectronvolt gamma-ray flare seven orders of magnitude -- tens of millions of times -- larger than the event horizon, or surface of the black hole itself.
Blood Test Might Alert Doctors to Problem Drinking
Drugs.com
DECEMBER 13, 2024
FRIDAY, Dec. 13, 2024 -- Have you been boozing more often than usual? A new blood test might be able to tell if you’re damaging your liver from too many beers, margaritas or belts of scotch, researchers report. A blood-borne byproduct of.
U.S. Adult Obesity Rate Fell in 2023, as Use of GLP-1 Meds Rose
Drugs.com
DECEMBER 13, 2024
FRIDAY, Dec. 13, 2024 -- The U.S. obesity rate declined for the first time in a decade last year, coinciding with the rise of GLP-1 weight-loss meds, a new study finds. Data on almost 17 million adults nationwide showed the obesity rate -- which.
From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Vault Snack #26 - Using Saved Searches to Automate Screening
Collaborative Drug
DECEMBER 13, 2024
Vault Snack #26 - Using Saved Searches to Automate Screening
In Mouse Studies, New Hope Against a Dangerous Complication of Pregnancy
Drugs.com
DECEMBER 13, 2024
FRIDAY, Dec. 13, 2024 -- The same technology behind COVID vaccines might be able to protect both the mother and child from a dangerous complication of pregnancy. A new mouse study published Dec. 11 in the journal Nature shows that injections based.
Exploring Extended Warheads toward Developing Cysteine-Targeted Covalent Kinase Inhibitors
Covalent Modifiers
DECEMBER 13, 2024
Zheng Zhao and Philip E. Bourne Journal of Chemical Information and Modeling 2024 DOI: 10.1021/acs.jcim.4c00890 In designing covalent kinase inhibitors (CKIs), the inclusion of electrophiles as attacking warheads demands careful choreography, ensuring not only their presence on the scaffold moiety but also their precise interaction with nucleophiles in the binding sites.
Who's Most Likely to Get the Mpox Shot in U.S.?
Drugs.com
DECEMBER 13, 2024
FRIDAY, Dec. 13, 2024 -- When an outbreak of mpox first hit the United States in 2022, a vaccine called Jynneos was available to help protect the most vulnerable population, gay and bisexual men. Now, there's new data showing which individuals in.
How Machine Learning Drives Clinical Trial Efficiency
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Tectorigenin Reduces Dabie bandavirus‐Induced Cytokine Storm by Regulating Toll‐Like Receptor 7/Extracellular Signal–Regulated Kinase Pathway
Chemical Biology and Drug Design
DECEMBER 13, 2024
Tectorigenin could reduce the expression levels of inflammatory cytokines in both DBV-infected THP-1 cells and plasma samples of IFNAR / mice infected with DBV. ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is a severe emerging infectious disease caused by Dabie bandavirus (DBV). Tectorigenin has been demonstrated to exert anti-inflammatory effect.
Newer Drug Imlunestrant Could Be Advance Against Tough-to-Treat Breast Cancers
Drugs.com
DECEMBER 13, 2024
FRIDAY, Dec. 13, 2024 -- An experimental hormone therapy pill has shown promise in extending the lives of women with tough-to-treat advanced breast cancer, a new clinical trial shows. The drug, imlunestrant, improved progression-free survival in.
Discovery of Voreloxin as a Dual‐Selective Stabilizer for c‐Myc/Bcl‐2 G‐Quadruplexes in Leukemia
Chemical Biology and Drug Design
DECEMBER 13, 2024
The stabilization of the G-quadruplex region in the c-Myc and Bcl-2 promoter genes by voreloxin leads to the downregulation of c-Myc and Bcl-2 expression, resulting in apoptosis of leukemia cells. ABSTRACT Overexpression of c-Myc is a key factor in the development of leukemia and other malignancies, highlighting the urgent need for novel drugs to inhibit c-Myc protein levels.
Matt Isbell Inspires Growth in Perficient’s Microsoft Practice
Perficient: Drug Development
DECEMBER 13, 2024
No matter the project, location, or career path, Perficient promises to challenge, champion, and celebrate every colleague on their journey to success. Perficient is a place where great minds and great companies converge to boldly advance business. Our colleagues bring fresh perspectives and innovative ideas to the table that inspire creativity, spark collaboration, and ignite change.
Deliver Fast, Flexible Clinical Trial Insights with Spotfire
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Who Will Pay for Prescription Drugs in 2032: Four Takeaways from the New Government Forecasts (rerun)
Drug Channels
DECEMBER 13, 2024
This week, Im rerunning some popular posts while I prepare for todays Drug Channels Outlook 2025 live video webinar. (If you sign up before 12 p.m. ET, you can attend the live event.) Click here to see the original post. The econowonks at the Centers for Medicare & Medicaid Services (CMS) recently released the latest projections for U.S. spending on healthcare.
New targeted therapies show promise in lung cancer treatment
Drug Target Review
DECEMBER 13, 2024
Lung cancer is the most commonly diagnosed cancer worldwide, representing 12.4 percent of all cases. It is also the leading cause of cancer-related deaths, accounting for 18.7 percent of total cancer fatalities. 1 Lung cancer is primarily classified into two types based on histological examination: Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC).
Up Close and Personal with Scott Myslinki, Director, Manufacturing
Alta Sciences
DECEMBER 13, 2024
Up Close and Personal with Scott Myslinki, Director, Manufacturing nbartlett Fri, 12/13/2024 - 22:48 Scott Myslinski began his career in contract drug manufacturing in 2012 and joined Altasciences in 2014 as a Manufacturing Associate. His knowledge of pharmaceutical manufacturing and proven experience with GMP practices led him to quickly grow within the company, rising to Manufacturing Manager in 2015 before assuming his current role as Director of Manufacturing in 2022.
Where is AI winning in drug discovery? 4 use cases to know
Fierce BioTech
DECEMBER 13, 2024
Even though AI-designed drugs arent yet a household term for FDA-approved, commercially available therapies, they are a reality in clinical development pipelines. | Even though AI-designed drugs arent yet a household term for FDA-approved, commercially available therapies, they are a reality in clinical development pipelines.
Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
A New Normal: Developer Productivity with Amazon Q Developer
Perficient: Drug Development
DECEMBER 13, 2024
Amazon Q was front and center at AWS re:Invent last week. Q Developer is emerging as required tooling for development teams focused on custom development, cloud-native services, and the wide range of legacy modernizations, stack conversions and migrations required of engineers. Q Developer is evolving beyond just code generation and is timing its maturity well alongside the rise of agentic workflows with dedicated agents playing specific roles within a process a familiar metaphor for enterprise
Title: Navigating the Generative AI Journey: A Strategic Roadmap for Healthcare Organizations
Perficient: Drug Development
DECEMBER 13, 2024
Doctor creating artificial intelligence interface 3D rendering Introduction The healthcare industry stands at a transformative crossroads with generative AI (GenAI) poised to revolutionize care delivery, operational efficiency, and patient outcomes. Recent MIT Technology Review research indicates that while 88% of organizations are using or experimenting with GenAI, healthcare organizations face unique challenges in implementation.
Universal Design for Visual Disabilities in Healthcare – Understanding Visual Disabilities -1
Perficient: Drug Development
DECEMBER 13, 2024
Creating a healthcare system that caters to the needs of individuals with visual disabilities is essential for providing inclusive and equitable care. Understanding visual disabilities is the first step towards implementing effective universal design principles in healthcare settings. Here’s a detailed look at visual disabilities and how they impact healthcare access and delivery.
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